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The map label for this gene is fruR [H]

Identifier: 28378717

GI number: 28378717

Start: 1888096

End: 1888851

Strand: Direct

Name: fruR [H]

Synonym: lp_2095

Alternate gene names: 28378717

Gene position: 1888096-1888851 (Clockwise)

Preceding gene: 28378715

Following gene: 28378718

Centisome position: 57.07

GC content: 47.49

Gene sequence:

>756_bases
GTGCTTACAGAAGAACGTCAACAGTACATTTTAAATACGATCCGTTTCAAGGGCATTATTAAAATCAAGGACATCTGTTC
TGAAACTCGTTGTTCCGAGTCCACGGCGCGCCGTGACCTCCAACAGCTAGAAGAACAGGGCGAGTTACTCCGCGTGCACG
GTGGTGCGAAGTATATGAACTCACTCCAAGAGGAACCCGCGATGAATGATAAGGTTTCCCGTAACGTTAACGCCAAGGAC
CATATCGCGCAGCAAGCCGTTGCGAACATTCAAGTTGATGACGTCATTTATTTGGATGCTGGGACTTCAACCCTAGCCAT
GATTCACCATTTAAATCCGAGCTACAACTTACGTGTCGTGACTAATGGTGTTGTCCATGCTTCCGCTTTGGCAGACATGG
GCATCCAAACCTACCTGCTTGGTGGCAATTTGAAAGGCACCACCAAAGCCGTGATTGGTCCCGAAGCCGTTAAATCGTTA
GAGGAATACCGATTCAACAAAGTTTTTCTTGGTATCAACGGTGTCCACCCAAAATTCGGGCTCACAACGCCCGACCCCGA
TGAAGCGGTCGTCAAAAAAACCGCAATTCTACAAAGTGAAGAAAGCTTTATCTTAGCTGACAACACTAAGTTCGACCACG
TTTCGTTTGCGCGCGTCGGTGATTTATCCAGTGCAACCATCATCACTGACCAACTCACGCCAAGCGTTGCCGAACAGTAT
CAACCATTAACTACGATTCAGGAGGTTCAATCATGA

Upstream 100 bases:

>100_bases
CGATTTGATGACAGATTTTGGATTATTTTGACGGTTTTTGAAGGTTTTTGTTGCATTTTGACGTTTAAACAGGTATATTA
TTATGCGGAGGGATTTGAAA

Downstream 100 bases:

>100_bases
TTTATACCATTACTGTCAATCCATCAATTGACTACGTGGTGCAACTACCCCAAATGACCCTCGGTAGTGTTAACCGGTTA
GCACACACGGCGAAACTCCC

Product: transcription regulator of fructose operon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLTEERQQYILNTIRFKGIIKIKDICSETRCSESTARRDLQQLEEQGELLRVHGGAKYMNSLQEEPAMNDKVSRNVNAKD
HIAQQAVANIQVDDVIYLDAGTSTLAMIHHLNPSYNLRVVTNGVVHASALADMGIQTYLLGGNLKGTTKAVIGPEAVKSL
EEYRFNKVFLGINGVHPKFGLTTPDPDEAVVKKTAILQSEESFILADNTKFDHVSFARVGDLSSATIITDQLTPSVAEQY
QPLTTIQEVQS

Sequences:

>Translated_251_residues
MLTEERQQYILNTIRFKGIIKIKDICSETRCSESTARRDLQQLEEQGELLRVHGGAKYMNSLQEEPAMNDKVSRNVNAKD
HIAQQAVANIQVDDVIYLDAGTSTLAMIHHLNPSYNLRVVTNGVVHASALADMGIQTYLLGGNLKGTTKAVIGPEAVKSL
EEYRFNKVFLGINGVHPKFGLTTPDPDEAVVKKTAILQSEESFILADNTKFDHVSFARVGDLSSATIITDQLTPSVAEQY
QPLTTIQEVQS
>Mature_251_residues
MLTEERQQYILNTIRFKGIIKIKDICSETRCSESTARRDLQQLEEQGELLRVHGGAKYMNSLQEEPAMNDKVSRNVNAKD
HIAQQAVANIQVDDVIYLDAGTSTLAMIHHLNPSYNLRVVTNGVVHASALADMGIQTYLLGGNLKGTTKAVIGPEAVKSL
EEYRFNKVFLGINGVHPKFGLTTPDPDEAVVKKTAILQSEESFILADNTKFDHVSFARVGDLSSATIITDQLTPSVAEQY
QPLTTIQEVQS

Specific function: Probable Repressor For The Aga Operon For N-Acetyl Galactosamine Transport And Metabolism. [C]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=237, Percent_Identity=29.957805907173, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI226510968, Length=241, Percent_Identity=32.3651452282158, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1789059, Length=233, Percent_Identity=30.4721030042918, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789829, Length=238, Percent_Identity=26.4705882352941, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1787540, Length=227, Percent_Identity=28.6343612334802, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI87082344, Length=232, Percent_Identity=26.2931034482759, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789170, Length=231, Percent_Identity=26.8398268398268, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1788069, Length=234, Percent_Identity=26.9230769230769, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1790753, Length=216, Percent_Identity=28.2407407407407, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787063, Length=234, Percent_Identity=25.6410256410256, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 27700; Mature: 27700

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTEERQQYILNTIRFKGIIKIKDICSETRCSESTARRDLQQLEEQGELLRVHGGAKYMN
CCCHHHHHHHHHHHHHHCEEEHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCHHHHH
SLQEEPAMNDKVSRNVNAKDHIAQQAVANIQVDDVIYLDAGTSTLAMIHHLNPSYNLRVV
HHHHCCCCCCHHHCCCCHHHHHHHHHHHCCEECCEEEEECCCHHEEHEEECCCCCEEEEE
TNGVVHASALADMGIQTYLLGGNLKGTTKAVIGPEAVKSLEEYRFNKVFLGINGVHPKFG
ECCCCHHHHHHHCCCEEEEECCCCCCCCEEEECHHHHHHHHHHCCCEEEEEECCCCCCCC
LTTPDPDEAVVKKTAILQSEESFILADNTKFDHVSFARVGDLSSATIITDQLTPSVAEQY
CCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEHHHHCCCCCCEEEECCCCHHHHHHC
QPLTTIQEVQS
CCHHHHHHHCC
>Mature Secondary Structure
MLTEERQQYILNTIRFKGIIKIKDICSETRCSESTARRDLQQLEEQGELLRVHGGAKYMN
CCCHHHHHHHHHHHHHHCEEEHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCHHHHH
SLQEEPAMNDKVSRNVNAKDHIAQQAVANIQVDDVIYLDAGTSTLAMIHHLNPSYNLRVV
HHHHCCCCCCHHHCCCCHHHHHHHHHHHCCEECCEEEEECCCHHEEHEEECCCCCEEEEE
TNGVVHASALADMGIQTYLLGGNLKGTTKAVIGPEAVKSLEEYRFNKVFLGINGVHPKFG
ECCCCHHHHHHHCCCEEEEECCCCCCCCEEEECHHHHHHHHHHCCCEEEEEECCCCCCCC
LTTPDPDEAVVKKTAILQSEESFILADNTKFDHVSFARVGDLSSATIITDQLTPSVAEQY
CCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCEEHHHHCCCCCCEEEECCCCHHHHHHC
QPLTTIQEVQS
CCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]