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The map label for this gene is pts16ABC [H]

Identifier: 28378719

GI number: 28378719

Start: 1889787

End: 1891754

Strand: Direct

Name: pts16ABC [H]

Synonym: lp_2097

Alternate gene names: 28378719

Gene position: 1889787-1891754 (Clockwise)

Preceding gene: 28378718

Following gene: 28378720

Centisome position: 57.12

GC content: 49.39

Gene sequence:

>1968_bases
ATGGATATCCGCGATTTATTACTAAAAGATGTCATGATCATGGACATGCACGCCACGACCAAGGACGAAGCGATTGATGA
GTTAGTTCATAAATATGCCGAACAAGGTATCATCAATGATGAGGCCCTCTACAAGCAAGACATCATCAAACGGGAAGCCG
AATCAACTACCGGGATTGGCGACGGGATTGCTATGCCCCATGCCAAAGATAAGGCTGTTAACCGGGCAACCGTGATGTTT
GCTAAGAGTAAGGCCGGCGTTGACTTCAACGCGTTAGATGGTCAACCCGTTCATCTTTTCTTCATGATTGCTGCTCCTGA
AGGTGCCAACAACACCCATTTAGCCGCCCTCGCCGCCCTCTCAAGCTTATTGATTGATCCTGAATTGGTCGCTAAACTTA
AGAATGCACAGTCACCTGAAGAAGTTCAACAACTCTTCGGTGATGCCCAGGCTGCTAAGGAAGAAAAGGAAGCCAAAGAT
GCAGCTGCCAAGGCCGAAAAAGAAGCCGCAGCTGCCAGCACCACCACTGACGAAAAACGTCCCTATTTAGTTGGGGTTAC
CGCCTGTCCAAACGGAATCGCCCATACTTACATGGCCGAAGCAGCCTTGATCAAAGCCGGTGAAGCGGCCGGTGTTGACA
TCAAAATCGAAACGAATGGTTCTGAAGGTGTTAAGCACTTATTGACTGCCGATGAAATCGCTCGTGCCGACGGTGTTGTG
ATCGCCGCTGACAAAAAGGTCAAGATGGCCCGTTTTGATGGTAAGCACCTGGTTAACCGTCCCGTTACTGACGGGATCAA
CAACGCCGATCAATTAGTTCAAGAAGCCTTGAGCGGTAAAGCTCCTGTCTATCACGATGCTGATGGTGGTGCTGCGGATG
ACGATGAAGGTGGCAGCGCTAATGGTAGCGTTTGGGGTGAAGTTTACAAAGACCTCATGAACGGGATTTCCCACATGTTG
CCATTCGTTGTTGGTGGTGGGATCTTAATGGCCCTCTCCTTCATTATTGAGCAATTCGTTGGTAGTAAGAGCTTAGCCTT
TACCTTCTTCAACCAAGCTGGTAACATGGCTTTCGCCTTCATGGTACCTGTTTTAGCCGGTTACATCGCCGAATCAATTG
GTGATCGTCCTGCTTTGATGCCCGGGTTCGTTGGTGGGTTCATGGCCACGGTTTACACTGGCGCTTACGGTGGTGTTTAC
ACGGCCTCCATTACCGCCAATGCTAAGAGTCCCGCTGGTTTCTTAGGTGGTTTAGCCGCTGGTTTCTTAGCCGGTTATAT
TACTGTTTGGATGAAGAAGTGGACCAAGAACATGCCACAATCCTTAGACGGGATGAAGCCAATGCTGATCTTCCCAATTC
TGGGCTTATTGATTATTGCTGCGCTAATGTTCTTCGTTGTTAACCCAATCTTCTCAGTTATCAACGCCTGGATTACCCAC
TTCCTAAACTCAATGGGTACTGGTAATGCCGTTCTCCTCGGGCTTGTCCTCGGTGGTATGATGTCGATCGATATGGGTGG
TCCTTTCAACAAGGCCGCTTACGTCTTCGCAACTGGTGCCTTTACCGCAACTGGACATGGGAACTTAATGGCCGCTGTTA
TGGCTGGTGGGATGGTTCCACCATTGGCAACTGCGATTGCAACTGCCTTCTGGCCAAAGAAGTTTACGGATGACGAACGT
AAAGCTGGTATCTCTAACTGGTTACTTGGTATTTCCTTCATTACTGAAGGTGCCATTCCATTCGCCACAGCTGACCCATT
GCACGTTATCGGTTCAAGTGTGATTGGTGCTGCCATCGCCGGTGGTTTAACTCAACTTTGGGGCGTTGCCGTCCCTGCTC
CTCATGGTGGCCTCTGGGTCTCATTACTCGCCACGAATATCTGGGGCTACATCGGTGCCACAATTATCGGTGCCGTTATC
GCTGGGGTTATCCTTGGTCTCTGGAAACCAGCTAAAGCTTCTAAATAA

Upstream 100 bases:

>100_bases
CTTCTCAGAAGACATTGCGACCCGCGCCAAGATCGATGAAATTTTGCCACTCATTAACATTGAAAAACTCGCTCACTAAA
GAAAGGACTGTTAACTAAAC

Downstream 100 bases:

>100_bases
TGTGATATCTAAAAAGACGATCAAATTGATCGTCTTTTTTTGTTTTCAAAATTAACGAATCAGCCGTCTAACCCCGCAAT
AAAACGGGTATAATGAAAGT

Product: fructose PTS, EIIABC

Products: NA

Alternate protein names: EIIABC-Fru; Fructose-specific phosphotransferase enzyme IIA component; EII-Fru; PTS system fructose-specific EIIA component; Fructose-specific phosphotransferase enzyme IIB component; EIII-Fru; PTS system fructose-specific EIIB component; Fructose permease IIC component; PTS system fructose-specific EIIC component [H]

Number of amino acids: Translated: 655; Mature: 655

Protein sequence:

>655_residues
MDIRDLLLKDVMIMDMHATTKDEAIDELVHKYAEQGIINDEALYKQDIIKREAESTTGIGDGIAMPHAKDKAVNRATVMF
AKSKAGVDFNALDGQPVHLFFMIAAPEGANNTHLAALAALSSLLIDPELVAKLKNAQSPEEVQQLFGDAQAAKEEKEAKD
AAAKAEKEAAAASTTTDEKRPYLVGVTACPNGIAHTYMAEAALIKAGEAAGVDIKIETNGSEGVKHLLTADEIARADGVV
IAADKKVKMARFDGKHLVNRPVTDGINNADQLVQEALSGKAPVYHDADGGAADDDEGGSANGSVWGEVYKDLMNGISHML
PFVVGGGILMALSFIIEQFVGSKSLAFTFFNQAGNMAFAFMVPVLAGYIAESIGDRPALMPGFVGGFMATVYTGAYGGVY
TASITANAKSPAGFLGGLAAGFLAGYITVWMKKWTKNMPQSLDGMKPMLIFPILGLLIIAALMFFVVNPIFSVINAWITH
FLNSMGTGNAVLLGLVLGGMMSIDMGGPFNKAAYVFATGAFTATGHGNLMAAVMAGGMVPPLATAIATAFWPKKFTDDER
KAGISNWLLGISFITEGAIPFATADPLHVIGSSVIGAAIAGGLTQLWGVAVPAPHGGLWVSLLATNIWGYIGATIIGAVI
AGVILGLWKPAKASK

Sequences:

>Translated_655_residues
MDIRDLLLKDVMIMDMHATTKDEAIDELVHKYAEQGIINDEALYKQDIIKREAESTTGIGDGIAMPHAKDKAVNRATVMF
AKSKAGVDFNALDGQPVHLFFMIAAPEGANNTHLAALAALSSLLIDPELVAKLKNAQSPEEVQQLFGDAQAAKEEKEAKD
AAAKAEKEAAAASTTTDEKRPYLVGVTACPNGIAHTYMAEAALIKAGEAAGVDIKIETNGSEGVKHLLTADEIARADGVV
IAADKKVKMARFDGKHLVNRPVTDGINNADQLVQEALSGKAPVYHDADGGAADDDEGGSANGSVWGEVYKDLMNGISHML
PFVVGGGILMALSFIIEQFVGSKSLAFTFFNQAGNMAFAFMVPVLAGYIAESIGDRPALMPGFVGGFMATVYTGAYGGVY
TASITANAKSPAGFLGGLAAGFLAGYITVWMKKWTKNMPQSLDGMKPMLIFPILGLLIIAALMFFVVNPIFSVINAWITH
FLNSMGTGNAVLLGLVLGGMMSIDMGGPFNKAAYVFATGAFTATGHGNLMAAVMAGGMVPPLATAIATAFWPKKFTDDER
KAGISNWLLGISFITEGAIPFATADPLHVIGSSVIGAAIAGGLTQLWGVAVPAPHGGLWVSLLATNIWGYIGATIIGAVI
AGVILGLWKPAKASK
>Mature_655_residues
MDIRDLLLKDVMIMDMHATTKDEAIDELVHKYAEQGIINDEALYKQDIIKREAESTTGIGDGIAMPHAKDKAVNRATVMF
AKSKAGVDFNALDGQPVHLFFMIAAPEGANNTHLAALAALSSLLIDPELVAKLKNAQSPEEVQQLFGDAQAAKEEKEAKD
AAAKAEKEAAAASTTTDEKRPYLVGVTACPNGIAHTYMAEAALIKAGEAAGVDIKIETNGSEGVKHLLTADEIARADGVV
IAADKKVKMARFDGKHLVNRPVTDGINNADQLVQEALSGKAPVYHDADGGAADDDEGGSANGSVWGEVYKDLMNGISHML
PFVVGGGILMALSFIIEQFVGSKSLAFTFFNQAGNMAFAFMVPVLAGYIAESIGDRPALMPGFVGGFMATVYTGAYGGVY
TASITANAKSPAGFLGGLAAGFLAGYITVWMKKWTKNMPQSLDGMKPMLIFPILGLLIIAALMFFVVNPIFSVINAWITH
FLNSMGTGNAVLLGLVLGGMMSIDMGGPFNKAAYVFATGAFTATGHGNLMAAVMAGGMVPPLATAIATAFWPKKFTDDER
KAGISNWLLGISFITEGAIPFATADPLHVIGSSVIGAAIAGGLTQLWGVAVPAPHGGLWVSLLATNIWGYIGATIIGAVI
AGVILGLWKPAKASK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1299

COG function: function code G; Phosphotransferase system, fructose-specific IIC component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788492, Length=472, Percent_Identity=40.8898305084746, Blast_Score=332, Evalue=6e-92,
Organism=Escherichia coli, GI1786951, Length=671, Percent_Identity=32.6378539493294, Blast_Score=330, Evalue=1e-91,
Organism=Escherichia coli, GI87082348, Length=456, Percent_Identity=32.4561403508772, Blast_Score=224, Evalue=2e-59,
Organism=Escherichia coli, GI1790386, Length=329, Percent_Identity=34.9544072948328, Blast_Score=156, Evalue=3e-39,
Organism=Escherichia coli, GI1788729, Length=395, Percent_Identity=29.873417721519, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI1789597, Length=141, Percent_Identity=31.9148936170213, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790387, Length=94, Percent_Identity=42.5531914893617, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788730, Length=94, Percent_Identity=37.2340425531915, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI2367327, Length=107, Percent_Identity=26.1682242990654, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR003352
- InterPro:   IPR013014
- InterPro:   IPR004715
- InterPro:   IPR003353
- InterPro:   IPR006327 [H]

Pfam domain/function: PF00359 PTS_EIIA_2; PF02378 PTS_EIIC; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 68565; Mature: 68565

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00372 PTS_EIIA_TYPE_2_HIS ; PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2 ; PS51104 PTS_EIIC_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIRDLLLKDVMIMDMHATTKDEAIDELVHKYAEQGIINDEALYKQDIIKREAESTTGIG
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
DGIAMPHAKDKAVNRATVMFAKSKAGVDFNALDGQPVHLFFMIAAPEGANNTHLAALAAL
CCCCCCCCHHHHCCHHEEEEEECCCCCCEECCCCCCEEEEEEEECCCCCCCHHHHHHHHH
SSLLIDPELVAKLKNAQSPEEVQQLFGDAQAAKEEKEAKDAAAKAEKEAAAASTTTDEKR
HHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PYLVGVTACPNGIAHTYMAEAALIKAGEAAGVDIKIETNGSEGVKHLLTADEIARADGVV
CEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEE
IAADKKVKMARFDGKHLVNRPVTDGINNADQLVQEALSGKAPVYHDADGGAADDDEGGSA
EEECCCEEEHHCCCHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCC
NGSVWGEVYKDLMNGISHMLPFVVGGGILMALSFIIEQFVGSKSLAFTFFNQAGNMAFAF
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
MVPVLAGYIAESIGDRPALMPGFVGGFMATVYTGAYGGVYTASITANAKSPAGFLGGLAA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHH
GFLAGYITVWMKKWTKNMPQSLDGMKPMLIFPILGLLIIAALMFFVVNPIFSVINAWITH
HHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLNSMGTGNAVLLGLVLGGMMSIDMGGPFNKAAYVFATGAFTATGHGNLMAAVMAGGMVP
HHHHCCCCHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCEEECCCCHHHHHHHHCCCCH
PLATAIATAFWPKKFTDDERKAGISNWLLGISFITEGAIPFATADPLHVIGSSVIGAAIA
HHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
GGLTQLWGVAVPAPHGGLWVSLLATNIWGYIGATIIGAVIAGVILGLWKPAKASK
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MDIRDLLLKDVMIMDMHATTKDEAIDELVHKYAEQGIINDEALYKQDIIKREAESTTGIG
CCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCC
DGIAMPHAKDKAVNRATVMFAKSKAGVDFNALDGQPVHLFFMIAAPEGANNTHLAALAAL
CCCCCCCCHHHHCCHHEEEEEECCCCCCEECCCCCCEEEEEEEECCCCCCCHHHHHHHHH
SSLLIDPELVAKLKNAQSPEEVQQLFGDAQAAKEEKEAKDAAAKAEKEAAAASTTTDEKR
HHHHCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PYLVGVTACPNGIAHTYMAEAALIKAGEAAGVDIKIETNGSEGVKHLLTADEIARADGVV
CEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEE
IAADKKVKMARFDGKHLVNRPVTDGINNADQLVQEALSGKAPVYHDADGGAADDDEGGSA
EEECCCEEEHHCCCHHHCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCC
NGSVWGEVYKDLMNGISHMLPFVVGGGILMALSFIIEQFVGSKSLAFTFFNQAGNMAFAF
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHH
MVPVLAGYIAESIGDRPALMPGFVGGFMATVYTGAYGGVYTASITANAKSPAGFLGGLAA
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHH
GFLAGYITVWMKKWTKNMPQSLDGMKPMLIFPILGLLIIAALMFFVVNPIFSVINAWITH
HHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FLNSMGTGNAVLLGLVLGGMMSIDMGGPFNKAAYVFATGAFTATGHGNLMAAVMAGGMVP
HHHHCCCCHHHHHHHHHHHHHEECCCCCCCCCEEEEEECCEEECCCCHHHHHHHHCCCCH
PLATAIATAFWPKKFTDDERKAGISNWLLGISFITEGAIPFATADPLHVIGSSVIGAAIA
HHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHH
GGLTQLWGVAVPAPHGGLWVSLLATNIWGYIGATIIGAVIAGVILGLWKPAKASK
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]