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The map label for this gene is ybhD [H]

Identifier: 28378514

GI number: 28378514

Start: 1678248

End: 1679177

Strand: Direct

Name: ybhD [H]

Synonym: lp_1857

Alternate gene names: 28378514

Gene position: 1678248-1679177 (Clockwise)

Preceding gene: 28378502

Following gene: 28378551

Centisome position: 50.73

GC content: 44.41

Gene sequence:

>930_bases
ATGCGTATTCAACAATTGCGCTACTTAGAAAAAATTGCCACGACTGGCTCGATCAACGAGGCGGCCAAACAGTTATTTAT
CAGCCAACCCTCATTATCCCAAGCAATGAAAGAACTCGAAAAGGAATATCAAGTACAGCTGTTTTATCGTCATAAAACGG
GGATCACTTTGACGGATGCGGGCCGTGAATTCATTAACTATTCTCGCAGTGTCCTCGACCAAGTTAATTTACTCAACGAA
CATTTTGGTCAGGGAACCGTTCGCAAGCGTATCTTTAGTGTCTCTGCGCAACACTATGCGTTTGTCGTGAACGCCTTTGT
CGAATTAGTCAAGGAAATTGGTGGCGATACCTATCAGTTCACATTACGCGAGACTGAAACGGCCAACGTGCTCAATGACG
TTCAGACTTTGAAAAGCGAGCTCGGCGTCATTTATCTTAATAAGTTCAATCAGACCGTGCTTAGCCGTTTGATTGCTGAC
AAAGACTTAAGCTTCGTACCGCTATTCGAGGCTCGCCCGCATGTTTTCGTCGGTCGTGATAACCCATTAACGCACAAGCA
AGACCTGACTTTGGATGACCTACGAGACTATCCCTACCTCTCTTATGAGCAAGGCGATACGAGTTCCTTTTATTTTGCAG
AAGAAATCCTCAGTACGCTACCTCATAAAAAGCATATCCGCATCAGTGATCGGGCAACGATCTTCAACTTGATGGTGGGT
TTAAACGGCTATACGATCAGTTCAGGCATCATCAGCAGCGAACTCAATGACGAAAAAATTGTGGCGATTCCACTAAAAGT
GGATGATGCAATGACCCTTGGATACCTGCGCCATAAGAAAATCGAATTGAGCGCTACGGCCCAGCGCTATTTGACACTAT
TGAAACAGCACATTCAAGGATATGGCTTTGACGTTTTTAATGATAATTGA

Upstream 100 bases:

>100_bases
TAGGCAATACCTATAACCTAAATAATTTATTCAATCACACCAGCTACAATCATGCGTTAATTAGATACTGAAACCAGACA
TTTCTCAGGAGGTGTACTTA

Downstream 100 bases:

>100_bases
CTGATCGACACATGCCGTGACTGAATTAATTTTTTGTTAACAGCATACAGTAGCGGGTTGTTTTTTGCAATTTTGATCAA
GGCCTTAATGTCCAAACCAC

Product: transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MRIQQLRYLEKIATTGSINEAAKQLFISQPSLSQAMKELEKEYQVQLFYRHKTGITLTDAGREFINYSRSVLDQVNLLNE
HFGQGTVRKRIFSVSAQHYAFVVNAFVELVKEIGGDTYQFTLRETETANVLNDVQTLKSELGVIYLNKFNQTVLSRLIAD
KDLSFVPLFEARPHVFVGRDNPLTHKQDLTLDDLRDYPYLSYEQGDTSSFYFAEEILSTLPHKKHIRISDRATIFNLMVG
LNGYTISSGIISSELNDEKIVAIPLKVDDAMTLGYLRHKKIELSATAQRYLTLLKQHIQGYGFDVFNDN

Sequences:

>Translated_309_residues
MRIQQLRYLEKIATTGSINEAAKQLFISQPSLSQAMKELEKEYQVQLFYRHKTGITLTDAGREFINYSRSVLDQVNLLNE
HFGQGTVRKRIFSVSAQHYAFVVNAFVELVKEIGGDTYQFTLRETETANVLNDVQTLKSELGVIYLNKFNQTVLSRLIAD
KDLSFVPLFEARPHVFVGRDNPLTHKQDLTLDDLRDYPYLSYEQGDTSSFYFAEEILSTLPHKKHIRISDRATIFNLMVG
LNGYTISSGIISSELNDEKIVAIPLKVDDAMTLGYLRHKKIELSATAQRYLTLLKQHIQGYGFDVFNDN
>Mature_309_residues
MRIQQLRYLEKIATTGSINEAAKQLFISQPSLSQAMKELEKEYQVQLFYRHKTGITLTDAGREFINYSRSVLDQVNLLNE
HFGQGTVRKRIFSVSAQHYAFVVNAFVELVKEIGGDTYQFTLRETETANVLNDVQTLKSELGVIYLNKFNQTVLSRLIAD
KDLSFVPLFEARPHVFVGRDNPLTHKQDLTLDDLRDYPYLSYEQGDTSSFYFAEEILSTLPHKKHIRISDRATIFNLMVG
LNGYTISSGIISSELNDEKIVAIPLKVDDAMTLGYLRHKKIELSATAQRYLTLLKQHIQGYGFDVFNDN

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI145693105, Length=295, Percent_Identity=26.1016949152542, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787530, Length=219, Percent_Identity=26.4840182648402, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788296, Length=219, Percent_Identity=26.9406392694064, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787601, Length=84, Percent_Identity=38.0952380952381, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788297, Length=203, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787879, Length=300, Percent_Identity=24, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1789506, Length=279, Percent_Identity=22.5806451612903, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788887, Length=304, Percent_Identity=22.6973684210526, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35375; Mature: 35375

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIQQLRYLEKIATTGSINEAAKQLFISQPSLSQAMKELEKEYQVQLFYRHKTGITLTDA
CCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEEEECCCEEEECC
GREFINYSRSVLDQVNLLNEHFGQGTVRKRIFSVSAQHYAFVVNAFVELVKEIGGDTYQF
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
TLRETETANVLNDVQTLKSELGVIYLNKFNQTVLSRLIADKDLSFVPLFEARPHVFVGRD
EEECCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECC
NPLTHKQDLTLDDLRDYPYLSYEQGDTSSFYFAEEILSTLPHKKHIRISDRATIFNLMVG
CCCCCCCCCCHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHC
LNGYTISSGIISSELNDEKIVAIPLKVDDAMTLGYLRHKKIELSATAQRYLTLLKQHIQG
CCCEEEECCCHHCCCCCCEEEEEEEECCCHHHHHHHHHCEEEHHHHHHHHHHHHHHHHHC
YGFDVFNDN
CCCEEECCC
>Mature Secondary Structure
MRIQQLRYLEKIATTGSINEAAKQLFISQPSLSQAMKELEKEYQVQLFYRHKTGITLTDA
CCHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHEEEEEEEECCCEEEECC
GREFINYSRSVLDQVNLLNEHFGQGTVRKRIFSVSAQHYAFVVNAFVELVKEIGGDTYQF
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
TLRETETANVLNDVQTLKSELGVIYLNKFNQTVLSRLIADKDLSFVPLFEARPHVFVGRD
EEECCHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHCCCCCEEEEECCCCCEEEECC
NPLTHKQDLTLDDLRDYPYLSYEQGDTSSFYFAEEILSTLPHKKHIRISDRATIFNLMVG
CCCCCCCCCCHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHC
LNGYTISSGIISSELNDEKIVAIPLKVDDAMTLGYLRHKKIELSATAQRYLTLLKQHIQG
CCCEEEECCCHHCCCCCCEEEEEEEECCCHHHHHHHHHCEEEHHHHHHHHHHHHHHHHHC
YGFDVFNDN
CCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]