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The map label for this gene is plsY

Identifier: 28378502

GI number: 28378502

Start: 1665238

End: 1665864

Strand: Direct

Name: plsY

Synonym: lp_1842

Alternate gene names: 28378502

Gene position: 1665238-1665864 (Clockwise)

Preceding gene: 28378495

Following gene: 28378514

Centisome position: 50.34

GC content: 44.02

Gene sequence:

>627_bases
TTGAAAATAATAATTATGCTGATCATCGCCTACTTAATTGGCGCGATTCCTTCGGGTGTCATTATTGGCAAGTTTTTCTT
TCACACTGATATTCGTCAAGCAGGTAGCGGTAATATCGGAACTACCAACACGTACCGGGTCCTAGGCCCGACCGCTGGGA
CAATTGTCATGGTGATGGATATTCTAAAAGGCACCATCGCAGCACTACAACCGACCTTGCTATTTCATATGAATAACCGG
TATACCTTATTGATTGGACTAGCAGCTATTTTAGGACATACTTTCTCAATTTACATCGGCTTTAAAGGTGGTAAGGCCGT
TGCCACGAGTGCTGGGATCTTATTGGCCTACAACTGGGAGTTCTTCTTAATTGCTAGTGCCATCATGTTATTATTGGTTT
ACACGACCAGTATGGTCAGTGTTGCTAGTATGACGGCTTTTCCAATCGTCACGTTGATTGCAATTTTTTACTATCAGGAT
TGGTTGCTATCACTCGTGGCCTTTGCATTGACCCTCTTCATCTTCTATCGGCACCGCAGTAATATTGCACGTATCAAAAA
CGGGACCGAATCATTGGTACACTTCGGACTTGGTTGGCGACGTCAGCAACGGGCTAACCGCAAATAA

Upstream 100 bases:

>100_bases
TAATTTGACACGCAATCATCATTTTTTAAACTAATTAATCCCCACAATCTTAAAAAGAATGCTAAAATATTGAGTGATTC
TATTGCAGGAGGAACCAACT

Downstream 100 bases:

>100_bases
TTATGTTACTTTCAAGACCATTTCATTACTGAGTGGTCTTTTTATTTAGGAACGGGTAAGCTTTGGTGCTGGGTTTGTAT
TTTTTGTTTCTAGTTAAAGT

Product: membrane protein

Products: NA

Alternate protein names: Acyl-PO4 G3P acyltransferase; Acyl-phosphate--glycerol-3-phosphate acyltransferase; G3P acyltransferase; GPAT; Lysophosphatidic acid synthase; LPA synthase

Number of amino acids: Translated: 208; Mature: 208

Protein sequence:

>208_residues
MKIIIMLIIAYLIGAIPSGVIIGKFFFHTDIRQAGSGNIGTTNTYRVLGPTAGTIVMVMDILKGTIAALQPTLLFHMNNR
YTLLIGLAAILGHTFSIYIGFKGGKAVATSAGILLAYNWEFFLIASAIMLLLVYTTSMVSVASMTAFPIVTLIAIFYYQD
WLLSLVAFALTLFIFYRHRSNIARIKNGTESLVHFGLGWRRQQRANRK

Sequences:

>Translated_208_residues
MKIIIMLIIAYLIGAIPSGVIIGKFFFHTDIRQAGSGNIGTTNTYRVLGPTAGTIVMVMDILKGTIAALQPTLLFHMNNR
YTLLIGLAAILGHTFSIYIGFKGGKAVATSAGILLAYNWEFFLIASAIMLLLVYTTSMVSVASMTAFPIVTLIAIFYYQD
WLLSLVAFALTLFIFYRHRSNIARIKNGTESLVHFGLGWRRQQRANRK
>Mature_208_residues
MKIIIMLIIAYLIGAIPSGVIIGKFFFHTDIRQAGSGNIGTTNTYRVLGPTAGTIVMVMDILKGTIAALQPTLLFHMNNR
YTLLIGLAAILGHTFSIYIGFKGGKAVATSAGILLAYNWEFFLIASAIMLLLVYTTSMVSVASMTAFPIVTLIAIFYYQD
WLLSLVAFALTLFIFYRHRSNIARIKNGTESLVHFGLGWRRQQRANRK

Specific function: Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP

COG id: COG0344

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the plsY family

Homologues:

Organism=Escherichia coli, GI1789439, Length=206, Percent_Identity=32.0388349514563, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PLSY_LACPL (Q88W28)

Other databases:

- EMBL:   AL935257
- RefSeq:   NP_785394.1
- GeneID:   1062227
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_1842
- NMPDR:   fig|220668.1.peg.1528
- HOGENOM:   HBG734487
- OMA:   SRIGEKK
- ProtClustDB:   PRK14392
- BioCyc:   LPLA220668:LP_1842-MONOMER
- HAMAP:   MF_01043
- InterPro:   IPR003811
- TIGRFAMs:   TIGR00023

Pfam domain/function: PF02660 DUF205

EC number: NA

Molecular weight: Translated: 23017; Mature: 23017

Theoretical pI: Translated: 10.77; Mature: 10.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xe7010d0)-; HASH(0xdb03504)-; HASH(0xe2fdda0)-; HASH(0xc6f9c0c)-; HASH(0xf0b2184)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIIMLIIAYLIGAIPSGVIIGKFFFHTDIRQAGSGNIGTTNTYRVLGPTAGTIVMVMD
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHH
ILKGTIAALQPTLLFHMNNRYTLLIGLAAILGHTFSIYIGFKGGKAVATSAGILLAYNWE
HHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCEEEEEEEECCCCEEEECCCEEEEECCH
FFLIASAIMLLLVYTTSMVSVASMTAFPIVTLIAIFYYQDWLLSLVAFALTLFIFYRHRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NIARIKNGTESLVHFGLGWRRQQRANRK
CHHHHCCCHHHHHHHCCCHHHHHHCCCH
>Mature Secondary Structure
MKIIIMLIIAYLIGAIPSGVIIGKFFFHTDIRQAGSGNIGTTNTYRVLGPTAGTIVMVMD
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHH
ILKGTIAALQPTLLFHMNNRYTLLIGLAAILGHTFSIYIGFKGGKAVATSAGILLAYNWE
HHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCEEEEEEEECCCCEEEECCCEEEEECCH
FFLIASAIMLLLVYTTSMVSVASMTAFPIVTLIAIFYYQDWLLSLVAFALTLFIFYRHRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
NIARIKNGTESLVHFGLGWRRQQRANRK
CHHHHCCCHHHHHHHCCCHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12566566