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The map label for this gene is secA

Identifier: 28377599

GI number: 28377599

Start: 675572

End: 677935

Strand: Direct

Name: secA

Synonym: lp_0739

Alternate gene names: 28377599

Gene position: 675572-677935 (Clockwise)

Preceding gene: 28377598

Following gene: 28377600

Centisome position: 20.42

GC content: 45.9

Gene sequence:

>2364_bases
ATGGCCAACATTTTAAAACGCTGGGTTGAAAGCGACAAGCGGACTATTCGGCGTCTGGATAAGATTGCTAATAAAGTTGA
AGCTTATGCCGACGAATACGGCAAGTTAAGTGATGCTGACTTGCAAGCGAAGACCCCAGAATTTCGTGAACGGTACAAGG
AGGGCGAATCGCTCGACGATTTGCTGCCCGAAGCATTTGCAACGGCGCGTGAAGGTGCGAAGCGGGTACTTGGTTTATAC
CCATTCCACGTTCAAATCCTCGGTGGAATTGTTTTGCATCAAGGTGACATTGCTGAAATGAAGACTGGTGAAGGGAAGAC
CTTAACGGCCACTATGCCAGTTTATTTGAATGCCATCTCTGGTAAGGGTGTTCACGTTGTAACAGTTAATGAATACTTAT
CAGCGCGTGATGCGACTGAAATGGGTGAACTGTATAACTGGTTAGGGATGAGCGTCGGAATCAACGGGGCTGAAAAGTCG
CCTGAAGAAAAACGTGCCGCTTATAACGCCGATATTACTTATTCGACGAACGGTGAAATTGGGTTCGATTACTTACGTGA
TAACATGGTGGTCTACCGTGAAGACATGGTGCAACGACCACTTAATTTTGCCATCATTGATGAAGTTGACTCAATCTTAA
TTGATGAAGCCCGGACACCGTTGATCATTTCTGGTCAATCAGAAGGTACAACGGGAATGTATAAGCGGGCTGACCGTTTT
GCTAAGACGTTGACGAAGGATGAAGATTACAAGGTTGACTTGGAATCTAAGACGGTCGCATTATTAGACGAAGGGATTCG
GAAGGCTGAAAAATACTTTGGCTTGGAAAACCTTTACGATACTGATAATACGGCGTTGAACCATTACTTGGATGAAGCTT
TGCGTGCGAACTACATCATGTTGAAAGATAAAGACTACGTGATTTCAGACGGTCAGGCGTTGATCGTTGATTCCTTTACG
GGGCGGATCATGGATGGTCGGCGCTTCTCAGACGGGTTACACCAAGCAATTGAAGCTAAGGAACACGTTGAGATTCAAGA
AGAAACCAAGACGATGGCGAATATCACGTACCAAAACTTATTCCGGATGTACAAAAAGTTATCTGGGATGACTGGGACGG
CCAAGACGGAACAAGAAGAATTCCGCGAAATCTATAACATGGAAGTTATTACGATTCCAACAAACCGCCCGATGATTCGT
GATGACCGTTCAGATTTGCTTTACCCAACGTTACAAAGCAAATTCAACGCGGTCGTTAAAGAAATCAAACAACTCCATGA
AAAGGGCCAACCAATGTTAATTGGGACCGTTGCCGTGGAAACGTCAGAATACTTGTCGCATCGCTTGGATGAGGAAAACA
TTCCGCACGTGGTCTTGAACGCCAAGAACCATGCGAAGGAAGCTGACATTGTTGCAAACGCCGGTCAACGTGGTGCGGTT
ACCATTGCCACCAACATGGCTGGTCGGGGGACCGATATCAAGTTGGGACCTGGTGTCAAAGAAGTCGGGGGGCTCGCCGT
TATTGGGACTGAACGTCATGAGTCCCGCCGGATTGATAACCAATTGCGGGGCCGTGCTGGTCGACAAGGTGATCCTGGTA
TGTCACAATTCTACCTCTCACTTGAAGACGATTTGATGCTACGGTTCGGTTCAGAACGAATCAAGAACTTCCTGCAACGG
ATGAATGTTGAAGATGATGATGCGGTTATTCAATCACGGATGATTACTCGACAGGTTGAGTCCGCTCAAAAACGGGTTGA
AGGGAACAACTATGACTCCCGGAAGAACGTTTTACAATATGATGATGTTATGCGGGCTCAACGTGAAGTGATTTACGGCG
AGCGGCAACAAGTCATTATGGAAGAAAAATCTTTGAAGCCCGTTATCATGCCAATGATCAAGCGGACCGTTGAACGGACC
GTTCAGTTACACATGCAAGGCGATGCCAAGGACTGGGATTTAGATGCAGTTGTTGACTTTGCCCAAGCTGCTATGGTGAA
GGAAGATTCAATTAGTGTGGCTGACTTGAAAGGTAAGTCGCCAGCAGAGGTTGAAGCTTACTTGATGGACCGGGTCGATA
AGATTTATGCGGACAAGGCTAAACAGCTTTACGATGCGGGTCAGATGCTAGAATTTGAAAAAGTCGTTATTCTGCGAGTG
GTCGATTCTCATTGGACGGATCACATTGATGCGATGGATCAATTACGGCAATCGATCGGTTTACGGGGCTATGGTCAATT
GAATCCGTTAGTTGAATATCAACGAGACGGTTACCAGATGTTTGAAGAAATGGTTGCGGATATTGATTATGATACGACGC
GACTCTTCATGAAGTCTGAAATTCGCCAAAATATTCAACGTTAA

Upstream 100 bases:

>100_bases
TCATTGCTAGTAAATAATGGTAAAATGACAGATGGTATTTTATTTTGAAATGGACAATTGAAATTAAAATTAAGATTAAT
TATTTGGAGAGGATACGTAA

Downstream 100 bases:

>100_bases
AATTTAACGTTAGTGCTAGCGAGTCTAAGACTAAGGTCTTAGGCTCGTTTTACAGTTAAACCAGATATTAAATAATTAAT
AAATAAGTTGAAAGAAGGGT

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 787; Mature: 786

Protein sequence:

>787_residues
MANILKRWVESDKRTIRRLDKIANKVEAYADEYGKLSDADLQAKTPEFRERYKEGESLDDLLPEAFATAREGAKRVLGLY
PFHVQILGGIVLHQGDIAEMKTGEGKTLTATMPVYLNAISGKGVHVVTVNEYLSARDATEMGELYNWLGMSVGINGAEKS
PEEKRAAYNADITYSTNGEIGFDYLRDNMVVYREDMVQRPLNFAIIDEVDSILIDEARTPLIISGQSEGTTGMYKRADRF
AKTLTKDEDYKVDLESKTVALLDEGIRKAEKYFGLENLYDTDNTALNHYLDEALRANYIMLKDKDYVISDGQALIVDSFT
GRIMDGRRFSDGLHQAIEAKEHVEIQEETKTMANITYQNLFRMYKKLSGMTGTAKTEQEEFREIYNMEVITIPTNRPMIR
DDRSDLLYPTLQSKFNAVVKEIKQLHEKGQPMLIGTVAVETSEYLSHRLDEENIPHVVLNAKNHAKEADIVANAGQRGAV
TIATNMAGRGTDIKLGPGVKEVGGLAVIGTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMLRFGSERIKNFLQR
MNVEDDDAVIQSRMITRQVESAQKRVEGNNYDSRKNVLQYDDVMRAQREVIYGERQQVIMEEKSLKPVIMPMIKRTVERT
VQLHMQGDAKDWDLDAVVDFAQAAMVKEDSISVADLKGKSPAEVEAYLMDRVDKIYADKAKQLYDAGQMLEFEKVVILRV
VDSHWTDHIDAMDQLRQSIGLRGYGQLNPLVEYQRDGYQMFEEMVADIDYDTTRLFMKSEIRQNIQR

Sequences:

>Translated_787_residues
MANILKRWVESDKRTIRRLDKIANKVEAYADEYGKLSDADLQAKTPEFRERYKEGESLDDLLPEAFATAREGAKRVLGLY
PFHVQILGGIVLHQGDIAEMKTGEGKTLTATMPVYLNAISGKGVHVVTVNEYLSARDATEMGELYNWLGMSVGINGAEKS
PEEKRAAYNADITYSTNGEIGFDYLRDNMVVYREDMVQRPLNFAIIDEVDSILIDEARTPLIISGQSEGTTGMYKRADRF
AKTLTKDEDYKVDLESKTVALLDEGIRKAEKYFGLENLYDTDNTALNHYLDEALRANYIMLKDKDYVISDGQALIVDSFT
GRIMDGRRFSDGLHQAIEAKEHVEIQEETKTMANITYQNLFRMYKKLSGMTGTAKTEQEEFREIYNMEVITIPTNRPMIR
DDRSDLLYPTLQSKFNAVVKEIKQLHEKGQPMLIGTVAVETSEYLSHRLDEENIPHVVLNAKNHAKEADIVANAGQRGAV
TIATNMAGRGTDIKLGPGVKEVGGLAVIGTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMLRFGSERIKNFLQR
MNVEDDDAVIQSRMITRQVESAQKRVEGNNYDSRKNVLQYDDVMRAQREVIYGERQQVIMEEKSLKPVIMPMIKRTVERT
VQLHMQGDAKDWDLDAVVDFAQAAMVKEDSISVADLKGKSPAEVEAYLMDRVDKIYADKAKQLYDAGQMLEFEKVVILRV
VDSHWTDHIDAMDQLRQSIGLRGYGQLNPLVEYQRDGYQMFEEMVADIDYDTTRLFMKSEIRQNIQR
>Mature_786_residues
ANILKRWVESDKRTIRRLDKIANKVEAYADEYGKLSDADLQAKTPEFRERYKEGESLDDLLPEAFATAREGAKRVLGLYP
FHVQILGGIVLHQGDIAEMKTGEGKTLTATMPVYLNAISGKGVHVVTVNEYLSARDATEMGELYNWLGMSVGINGAEKSP
EEKRAAYNADITYSTNGEIGFDYLRDNMVVYREDMVQRPLNFAIIDEVDSILIDEARTPLIISGQSEGTTGMYKRADRFA
KTLTKDEDYKVDLESKTVALLDEGIRKAEKYFGLENLYDTDNTALNHYLDEALRANYIMLKDKDYVISDGQALIVDSFTG
RIMDGRRFSDGLHQAIEAKEHVEIQEETKTMANITYQNLFRMYKKLSGMTGTAKTEQEEFREIYNMEVITIPTNRPMIRD
DRSDLLYPTLQSKFNAVVKEIKQLHEKGQPMLIGTVAVETSEYLSHRLDEENIPHVVLNAKNHAKEADIVANAGQRGAVT
IATNMAGRGTDIKLGPGVKEVGGLAVIGTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMLRFGSERIKNFLQRM
NVEDDDAVIQSRMITRQVESAQKRVEGNNYDSRKNVLQYDDVMRAQREVIYGERQQVIMEEKSLKPVIMPMIKRTVERTV
QLHMQGDAKDWDLDAVVDFAQAAMVKEDSISVADLKGKSPAEVEAYLMDRVDKIYADKAKQLYDAGQMLEFEKVVILRVV
DSHWTDHIDAMDQLRQSIGLRGYGQLNPLVEYQRDGYQMFEEMVADIDYDTTRLFMKSEIRQNIQR

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=825, Percent_Identity=45.9393939393939, Blast_Score=696, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_LACPL (Q88YL7)

Other databases:

- EMBL:   AL935254
- RefSeq:   NP_784491.1
- HSSP:   P28366
- ProteinModelPortal:   Q88YL7
- SMR:   Q88YL7
- GeneID:   1063458
- GenomeReviews:   AL935263_GR
- KEGG:   lpl:lp_0739
- NMPDR:   fig|220668.1.peg.625
- HOGENOM:   HBG284200
- OMA:   GGMVLHD
- ProtClustDB:   PRK12906
- BioCyc:   LPLA220668:LP_0739-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 89560; Mature: 89429

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANILKRWVESDKRTIRRLDKIANKVEAYADEYGKLSDADLQAKTPEFRERYKEGESLDD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHH
LLPEAFATAREGAKRVLGLYPFHVQILGGIVLHQGDIAEMKTGEGKTLTATMPVYLNAIS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCHHHCCCCCCCEEEEECCEEEEEEC
GKGVHVVTVNEYLSARDATEMGELYNWLGMSVGINGAEKSPEEKRAAYNADITYSTNGEI
CCCEEEEEHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEEEECCCCC
GFDYLRDNMVVYREDMVQRPLNFAIIDEVDSILIDEARTPLIISGQSEGTTGMYKRADRF
CHHHHHCCEEEEEHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH
AKTLTKDEDYKVDLESKTVALLDEGIRKAEKYFGLENLYDTDNTALNHYLDEALRANYIM
HHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCEEE
LKDKDYVISDGQALIVDSFTGRIMDGRRFSDGLHQAIEAKEHVEIQEETKTMANITYQNL
EECCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
FRMYKKLSGMTGTAKTEQEEFREIYNMEVITIPTNRPMIRDDRSDLLYPTLQSKFNAVVK
HHHHHHHCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCHHCHHHHHHHHHHHHH
EIKQLHEKGQPMLIGTVAVETSEYLSHRLDEENIPHVVLNAKNHAKEADIVANAGQRGAV
HHHHHHHCCCCEEEEEEEECHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHCCCCCCEE
TIATNMAGRGTDIKLGPGVKEVGGLAVIGTERHESRRIDNQLRGRAGRQGDPGMSQFYLS
EEEECCCCCCCCEEECCCHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHEEEE
LEDDLMLRFGSERIKNFLQRMNVEDDDAVIQSRMITRQVESAQKRVEGNNYDSRKNVLQY
CCHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
DDVMRAQREVIYGERQQVIMEEKSLKPVIMPMIKRTVERTVQLHMQGDAKDWDLDAVVDF
HHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHH
AQAAMVKEDSISVADLKGKSPAEVEAYLMDRVDKIYADKAKQLYDAGQMLEFEKVVILRV
HHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHH
VDSHWTDHIDAMDQLRQSIGLRGYGQLNPLVEYQRDGYQMFEEMVADIDYDTTRLFMKSE
HHHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IRQNIQR
HHHHHCC
>Mature Secondary Structure 
ANILKRWVESDKRTIRRLDKIANKVEAYADEYGKLSDADLQAKTPEFRERYKEGESLDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHH
LLPEAFATAREGAKRVLGLYPFHVQILGGIVLHQGDIAEMKTGEGKTLTATMPVYLNAIS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEECCCHHHCCCCCCCEEEEECCEEEEEEC
GKGVHVVTVNEYLSARDATEMGELYNWLGMSVGINGAEKSPEEKRAAYNADITYSTNGEI
CCCEEEEEHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCEEEECCCCC
GFDYLRDNMVVYREDMVQRPLNFAIIDEVDSILIDEARTPLIISGQSEGTTGMYKRADRF
CHHHHHCCEEEEEHHHHHCCCCEEEHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHH
AKTLTKDEDYKVDLESKTVALLDEGIRKAEKYFGLENLYDTDNTALNHYLDEALRANYIM
HHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHCCEEE
LKDKDYVISDGQALIVDSFTGRIMDGRRFSDGLHQAIEAKEHVEIQEETKTMANITYQNL
EECCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
FRMYKKLSGMTGTAKTEQEEFREIYNMEVITIPTNRPMIRDDRSDLLYPTLQSKFNAVVK
HHHHHHHCCCCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCHHCHHHHHHHHHHHHH
EIKQLHEKGQPMLIGTVAVETSEYLSHRLDEENIPHVVLNAKNHAKEADIVANAGQRGAV
HHHHHHHCCCCEEEEEEEECHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHCCCCCCEE
TIATNMAGRGTDIKLGPGVKEVGGLAVIGTERHESRRIDNQLRGRAGRQGDPGMSQFYLS
EEEECCCCCCCCEEECCCHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCHHHEEEE
LEDDLMLRFGSERIKNFLQRMNVEDDDAVIQSRMITRQVESAQKRVEGNNYDSRKNVLQY
CCHHHHHHHCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
DDVMRAQREVIYGERQQVIMEEKSLKPVIMPMIKRTVERTVQLHMQGDAKDWDLDAVVDF
HHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHEEEECCCCCCCCHHHHHHH
AQAAMVKEDSISVADLKGKSPAEVEAYLMDRVDKIYADKAKQLYDAGQMLEFEKVVILRV
HHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHH
VDSHWTDHIDAMDQLRQSIGLRGYGQLNPLVEYQRDGYQMFEEMVADIDYDTTRLFMKSE
HHHHCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
IRQNIQR
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12566566