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The map label for this gene is tadA [H]

Identifier: 28377565

GI number: 28377565

Start: 641949

End: 642455

Strand: Direct

Name: tadA [H]

Synonym: lp_0696

Alternate gene names: 28377565

Gene position: 641949-642455 (Clockwise)

Preceding gene: 28377564

Following gene: 28377566

Centisome position: 19.4

GC content: 48.72

Gene sequence:

>507_bases
GTGACGGAACCAACAGCGGAAGACTGGATGCAAGAAGCATTACATGAAGCGCGGATGGCCTACTTAATTGGCGAAGTGCC
GATTGGGGCCGTGATCGTTCACCAGGGTGAAATTATTGGCCGTGGTCACAATTTACGGGAGCATGGTCAGGATGCAACGA
TGCACGCGGAAATTATTGCGATTCAGGAAGCTTGCGAATATTTGCATAGTTGGCGATTAGCCGATTGTCAGCTATATGTC
ACCTTGGAACCATGTTTGATGTGTAGTGGGGCTATTATTAATGCACGGCTACCTGAACTCTACTTTGGTGCCCGTGATCC
CAAGGCTGGCGCCGTTCGTAGTTTGTATCAGGTGATGGATGATACCCGGTTAAATCATCAAGTAACGGTTCATGAACGCA
TCTTGGCACGTCCGGCCGGCGAGATGTTGGAAAACTTCTTCCGTGGGATTCGTAAACGGAAAAAGGCGGCTAAAAAAGCA
CGACGTGAAGCTGCTGAAAAAAATTAG

Upstream 100 bases:

>100_bases
CATCTGCGAAGAAATTGATGCAAACGACCTTTGGTAATTGTCAGGTGATTAAGAAGGACAAAGGGTATTACATCCTACAA
AGTGTAAAGGAGGGATAGTC

Downstream 100 bases:

>100_bases
GCCGATGGCTGGTAATTGTGGCGCAAATCATGTATTATAGTATTTGCCGCAAGGCCAAAAGGCAAGGGTGGATTTACGAA
TCGTGTCAGGTCCGGAAGGA

Product: cytosine/adenosine deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MTEPTAEDWMQEALHEARMAYLIGEVPIGAVIVHQGEIIGRGHNLREHGQDATMHAEIIAIQEACEYLHSWRLADCQLYV
TLEPCLMCSGAIINARLPELYFGARDPKAGAVRSLYQVMDDTRLNHQVTVHERILARPAGEMLENFFRGIRKRKKAAKKA
RREAAEKN

Sequences:

>Translated_168_residues
MTEPTAEDWMQEALHEARMAYLIGEVPIGAVIVHQGEIIGRGHNLREHGQDATMHAEIIAIQEACEYLHSWRLADCQLYV
TLEPCLMCSGAIINARLPELYFGARDPKAGAVRSLYQVMDDTRLNHQVTVHERILARPAGEMLENFFRGIRKRKKAAKKA
RREAAEKN
>Mature_167_residues
TEPTAEDWMQEALHEARMAYLIGEVPIGAVIVHQGEIIGRGHNLREHGQDATMHAEIIAIQEACEYLHSWRLADCQLYVT
LEPCLMCSGAIINARLPELYFGARDPKAGAVRSLYQVMDDTRLNHQVTVHERILARPAGEMLENFFRGIRKRKKAAKKAR
REAAEKN

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=169, Percent_Identity=28.9940828402367, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI145693172, Length=160, Percent_Identity=45, Blast_Score=135, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17554608, Length=106, Percent_Identity=38.6792452830189, Blast_Score=86, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17541138, Length=155, Percent_Identity=34.8387096774194, Blast_Score=84, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17555996, Length=136, Percent_Identity=33.8235294117647, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325319, Length=109, Percent_Identity=39.4495412844037, Blast_Score=75, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355527, Length=147, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 19046; Mature: 18915

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEPTAEDWMQEALHEARMAYLIGEVPIGAVIVHQGEIIGRGHNLREHGQDATMHAEIIA
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCCHHHCCCCCHHHHHHHH
IQEACEYLHSWRLADCQLYVTLEPCLMCSGAIINARLPELYFGARDPKAGAVRSLYQVMD
HHHHHHHHHCCCCCCEEEEEEECHHHHHCCCHHCCCCCHHHCCCCCCCHHHHHHHHHHHH
DTRLNHQVTVHERILARPAGEMLENFFRGIRKRKKAAKKARREAAEKN
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEPTAEDWMQEALHEARMAYLIGEVPIGAVIVHQGEIIGRGHNLREHGQDATMHAEIIA
CCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCCCHHHCCCCCHHHHHHHH
IQEACEYLHSWRLADCQLYVTLEPCLMCSGAIINARLPELYFGARDPKAGAVRSLYQVMD
HHHHHHHHHCCCCCCEEEEEEECHHHHHCCCHHCCCCCHHHCCCCCCCHHHHHHHHHHHH
DTRLNHQVTVHERILARPAGEMLENFFRGIRKRKKAAKKARREAAEKN
CCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]