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The map label for this gene is radA [H]

Identifier: 28377483

GI number: 28377483

Start: 576649

End: 578028

Strand: Direct

Name: radA [H]

Synonym: lp_0606

Alternate gene names: 28377483

Gene position: 576649-578028 (Clockwise)

Preceding gene: 28377482

Following gene: 28377484

Centisome position: 17.43

GC content: 46.67

Gene sequence:

>1380_bases
GTGGCAAAAGCAAAAACTCAGTTTGTTTGTTCTAACTGTGGTTATTCAACACCGCGATATTTAGGACGGTGTCCGAACTG
TGGTGAATGGAATACACTAACTGAAGAACATTTTGATACAAAACCGGACCGCAAGTCGCGGGTGAGCTTTGCGGGTAAGT
CGGCTAAGCCACAACGACTCAAAGAAGTGTCGCTGACTAAGACACCGCGTGTCAAGACTAAGCTGAAAGAGTTCAACCGG
GTCTTAGGTGGCGGTGTTGTGCCAGGTTCACTAGTTTTGATCGGTGGTGATCCAGGTATTGGTAAGTCAACGTTACTACT
GCAAGTTTCGGGGCAATTGGCCGAGACGGGTGGTTCCGTACTATACGTGACTGGTGAAGAAAGTGCCTCCCAAGTGAAGA
TGCGGGCGGACCGGCTGGCTGTTAGCAGTGAAGACTTTTATCTTTATCCTGAGACTGATATGTCGAATATTCGTTCAACG
ATTGAATCGACGCATCCAGAATTTGTGGTCATTGATTCGGTACAAACGATGCAAGAACCTGATATGGACTCTGCGATTGG
TTCAGTATCACAAATCCGTGAAATTACGGCTGAACTACTGCAAATTGCGAAGACTAACGGCATTACCATTTTTATTGTGG
GCCATGTGACTAAGGGTGGTGCCATTGCGGGGCCTAAGATCTTAGAACATATGGTTGATACCGTTTTGTACTTTGAAGGT
GATTTACATCATACGTACCGCATTTTACGGGCAGTCAAGAATCGATTCGGGTCAACGAATGAACTGGGAATATTTGAGAT
GCGGACGGGCGGTTTGTATGAAGTGGCCAATCCGTCAGAGATCTTCTTGGAAGAACGTCTGAAGGATGCTACGGGTTCCG
CCATCGTTGTTTCAATGGAAGGAACACGACCAATCTTAGTAGAAGTTCAAGCGCTGGTAACGCCAACGGTCTTTGGTAAT
GCGAAGCGGACCGCAAGTGGCTTGGATCATAATCGAGTCTCCTTGATTATGGCAGTGTTGGAAAAACGGGCGAGTCTAAT
GCTTCAGAACCAGGACGCGTATTTGAAAGCGGCCGGTGGCGTTAAGTTAGATGAACCGGCGATTGACTTAGCTATTGCGG
TCAGTGTGGCTTCTAGTTATCGTGACCAGCAGACTCGTCCGAGTGACTGTTTTGTTGGTGAAGTCGGTTTGACTGGTGAG
ATTCGGCGGGTCAACCGGATTGAATCACGAGTTGGTGAGGCGGCTAAGCTAGGTTTTAAACGTATCTTTATTCCTAAGAA
TAATCTGCAAGGTTGGGATATCCCAACTGGAATCGAAGTAATTGGAGTTGCCACGCTAAAAGAAGCGCTCCAATTAGCAT
TACAACAACCAAATTATTAA

Upstream 100 bases:

>100_bases
ATGACTCATGACAGTGTGACGCGGATGAAGTAATTATTTTAGAAATTCCAATACCCAACATTAAATTGATATGTTGGCGG
AGAAATGGAGACGTGTGTAC

Downstream 100 bases:

>100_bases
AAAGGGGCTGATGCCATGAAGAAGTTAACGGTGCGACTAGTATTTATTGTCGTCGGGGGTACGTTAGGACTAACTTACCT
GCCGTTCTTGTGGACGACAA

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MAKAKTQFVCSNCGYSTPRYLGRCPNCGEWNTLTEEHFDTKPDRKSRVSFAGKSAKPQRLKEVSLTKTPRVKTKLKEFNR
VLGGGVVPGSLVLIGGDPGIGKSTLLLQVSGQLAETGGSVLYVTGEESASQVKMRADRLAVSSEDFYLYPETDMSNIRST
IESTHPEFVVIDSVQTMQEPDMDSAIGSVSQIREITAELLQIAKTNGITIFIVGHVTKGGAIAGPKILEHMVDTVLYFEG
DLHHTYRILRAVKNRFGSTNELGIFEMRTGGLYEVANPSEIFLEERLKDATGSAIVVSMEGTRPILVEVQALVTPTVFGN
AKRTASGLDHNRVSLIMAVLEKRASLMLQNQDAYLKAAGGVKLDEPAIDLAIAVSVASSYRDQQTRPSDCFVGEVGLTGE
IRRVNRIESRVGEAAKLGFKRIFIPKNNLQGWDIPTGIEVIGVATLKEALQLALQQPNY

Sequences:

>Translated_459_residues
MAKAKTQFVCSNCGYSTPRYLGRCPNCGEWNTLTEEHFDTKPDRKSRVSFAGKSAKPQRLKEVSLTKTPRVKTKLKEFNR
VLGGGVVPGSLVLIGGDPGIGKSTLLLQVSGQLAETGGSVLYVTGEESASQVKMRADRLAVSSEDFYLYPETDMSNIRST
IESTHPEFVVIDSVQTMQEPDMDSAIGSVSQIREITAELLQIAKTNGITIFIVGHVTKGGAIAGPKILEHMVDTVLYFEG
DLHHTYRILRAVKNRFGSTNELGIFEMRTGGLYEVANPSEIFLEERLKDATGSAIVVSMEGTRPILVEVQALVTPTVFGN
AKRTASGLDHNRVSLIMAVLEKRASLMLQNQDAYLKAAGGVKLDEPAIDLAIAVSVASSYRDQQTRPSDCFVGEVGLTGE
IRRVNRIESRVGEAAKLGFKRIFIPKNNLQGWDIPTGIEVIGVATLKEALQLALQQPNY
>Mature_458_residues
AKAKTQFVCSNCGYSTPRYLGRCPNCGEWNTLTEEHFDTKPDRKSRVSFAGKSAKPQRLKEVSLTKTPRVKTKLKEFNRV
LGGGVVPGSLVLIGGDPGIGKSTLLLQVSGQLAETGGSVLYVTGEESASQVKMRADRLAVSSEDFYLYPETDMSNIRSTI
ESTHPEFVVIDSVQTMQEPDMDSAIGSVSQIREITAELLQIAKTNGITIFIVGHVTKGGAIAGPKILEHMVDTVLYFEGD
LHHTYRILRAVKNRFGSTNELGIFEMRTGGLYEVANPSEIFLEERLKDATGSAIVVSMEGTRPILVEVQALVTPTVFGNA
KRTASGLDHNRVSLIMAVLEKRASLMLQNQDAYLKAAGGVKLDEPAIDLAIAVSVASSYRDQQTRPSDCFVGEVGLTGEI
RRVNRIESRVGEAAKLGFKRIFIPKNNLQGWDIPTGIEVIGVATLKEALQLALQQPNY

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=459, Percent_Identity=47.276688453159, Blast_Score=410, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 50020; Mature: 49889

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAKTQFVCSNCGYSTPRYLGRCPNCGEWNTLTEEHFDTKPDRKSRVSFAGKSAKPQRL
CCCCCCHHHCCCCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHEECCCCCCHHHH
KEVSLTKTPRVKTKLKEFNRVLGGGVVPGSLVLIGGDPGIGKSTLLLQVSGQLAETGGSV
HHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEEECCCHHHCCCCE
LYVTGEESASQVKMRADRLAVSSEDFYLYPETDMSNIRSTIESTHPEFVVIDSVQTMQEP
EEEECCCCHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHCCCCEEEECCHHHHCCC
DMDSAIGSVSQIREITAELLQIAKTNGITIFIVGHVTKGGAIAGPKILEHMVDTVLYFEG
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCC
DLHHTYRILRAVKNRFGSTNELGIFEMRTGGLYEVANPSEIFLEERLKDATGSAIVVSME
CHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHCCCCCEEEEEEC
GTRPILVEVQALVTPTVFGNAKRTASGLDHNRVSLIMAVLEKRASLMLQNQDAYLKAAGG
CCCCEEEEEEHHHCCHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEECCC
VKLDEPAIDLAIAVSVASSYRDQQTRPSDCFVGEVGLTGEIRRVNRIESRVGEAAKLGFK
CEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHCCEE
RIFIPKNNLQGWDIPTGIEVIGVATLKEALQLALQQPNY
EEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AKAKTQFVCSNCGYSTPRYLGRCPNCGEWNTLTEEHFDTKPDRKSRVSFAGKSAKPQRL
CCCCCHHHCCCCCCCCHHHHCCCCCCCCCCCCCHHHCCCCCCHHHHHEECCCCCCHHHH
KEVSLTKTPRVKTKLKEFNRVLGGGVVPGSLVLIGGDPGIGKSTLLLQVSGQLAETGGSV
HHCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCEEEEEECCCHHHCCCCE
LYVTGEESASQVKMRADRLAVSSEDFYLYPETDMSNIRSTIESTHPEFVVIDSVQTMQEP
EEEECCCCHHHHHHHHHHHEECCCCEEEECCCCHHHHHHHHHHCCCCEEEECCHHHHCCC
DMDSAIGSVSQIREITAELLQIAKTNGITIFIVGHVTKGGAIAGPKILEHMVDTVLYFEG
CHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHHCCC
DLHHTYRILRAVKNRFGSTNELGIFEMRTGGLYEVANPSEIFLEERLKDATGSAIVVSME
CHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEECCCHHHHHHHHHHCCCCCEEEEEEC
GTRPILVEVQALVTPTVFGNAKRTASGLDHNRVSLIMAVLEKRASLMLQNQDAYLKAAGG
CCCCEEEEEEHHHCCHHCCCCHHHHCCCCCHHHHHHHHHHHHHHHHEECCCCCEEEECCC
VKLDEPAIDLAIAVSVASSYRDQQTRPSDCFVGEVGLTGEIRRVNRIESRVGEAAKLGFK
CEECCCHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHCHHHHCCEE
RIFIPKNNLQGWDIPTGIEVIGVATLKEALQLALQQPNY
EEEEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]