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The map label for this gene is fkpB [C]

Identifier: 239618113

GI number: 239618113

Start: 1876334

End: 1876762

Strand: Reverse

Name: fkpB [C]

Synonym: Kole_1745

Alternate gene names: 239618113

Gene position: 1876762-1876334 (Counterclockwise)

Preceding gene: 239618114

Following gene: 239618111

Centisome position: 81.52

GC content: 44.99

Gene sequence:

>429_bases
ATGCCAGAAGCAAAAAAGGGCGACACCGTAAAAGTACATTATACCGGAAGATTCGAGGACGGAGAGATCTTTGATTCCTC
CACTGGAAAAGAGCCGTTAGAATTCACCATCGGTAAAGGAGAGGTAATTCCCGGATTTGAAGAAGCGATCATAGGAATGA
ATACAGGGGAATCGAAGACAGTAAAAATTCCACCGGAAAAAGCTTATGGTCCTCGATACGATGAACTCGTTTTGACGGTT
GAACGTTCACGTTTTCCGGATGATATGGAGCCACAGTTAGGTCAACAACTTCAGTTGAGACAACCGGATGGCAGAACCTT
CATAGTAACCATCACCGACATCAACGAAACAGCGGTAACGCTCGATGCGAACCACCCACTAGCGGGAAAAGATCTCGTAT
TTGAAATCAACCTCATAGAGATCGTTTGA

Upstream 100 bases:

>100_bases
TTTATGTTGGAAATTTTACGTCTTTTATGAAGTTTGCTGGTATAATGAAAAGGTACCTGTGCGGTCAGGTATTAAATTGT
GATATCGAAAGGAGAAAACT

Downstream 100 bases:

>100_bases
AATGAACGACAACAGCAAAGCTCTGCCCGGGAATCCCCCGGCAGAGCTTTGTTATTTGTCAAAGGTCAAAATAAAGCTGG
TATTCCGCGGGACTTGGCAC

Product: peptidylprolyl isomerase FKBP-type

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MPEAKKGDTVKVHYTGRFEDGEIFDSSTGKEPLEFTIGKGEVIPGFEEAIIGMNTGESKTVKIPPEKAYGPRYDELVLTV
ERSRFPDDMEPQLGQQLQLRQPDGRTFIVTITDINETAVTLDANHPLAGKDLVFEINLIEIV

Sequences:

>Translated_142_residues
MPEAKKGDTVKVHYTGRFEDGEIFDSSTGKEPLEFTIGKGEVIPGFEEAIIGMNTGESKTVKIPPEKAYGPRYDELVLTV
ERSRFPDDMEPQLGQQLQLRQPDGRTFIVTITDINETAVTLDANHPLAGKDLVFEINLIEIV
>Mature_141_residues
PEAKKGDTVKVHYTGRFEDGEIFDSSTGKEPLEFTIGKGEVIPGFEEAIIGMNTGESKTVKIPPEKAYGPRYDELVLTVE
RSRFPDDMEPQLGQQLQLRQPDGRTFIVTITDINETAVTLDANHPLAGKDLVFEINLIEIV

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=71, Percent_Identity=43.6619718309859, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI17149844, Length=71, Percent_Identity=43.6619718309859, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI17149842, Length=71, Percent_Identity=43.6619718309859, Blast_Score=70, Evalue=7e-13,
Organism=Homo sapiens, GI7706131, Length=66, Percent_Identity=43.9393939393939, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI219842220, Length=69, Percent_Identity=43.4782608695652, Blast_Score=67, Evalue=4e-12,
Organism=Homo sapiens, GI17149836, Length=86, Percent_Identity=43.0232558139535, Blast_Score=66, Evalue=1e-11,
Organism=Homo sapiens, GI4503725, Length=86, Percent_Identity=43.0232558139535, Blast_Score=66, Evalue=1e-11,
Organism=Homo sapiens, GI33469985, Length=68, Percent_Identity=44.1176470588235, Blast_Score=65, Evalue=2e-11,
Organism=Homo sapiens, GI4503727, Length=76, Percent_Identity=40.7894736842105, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786211, Length=138, Percent_Identity=30.4347826086957, Blast_Score=79, Evalue=1e-16,
Organism=Escherichia coli, GI1789748, Length=134, Percent_Identity=35.0746268656716, Blast_Score=67, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17540882, Length=71, Percent_Identity=43.6619718309859, Blast_Score=68, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320727, Length=72, Percent_Identity=45.8333333333333, Blast_Score=67, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323566, Length=69, Percent_Identity=39.1304347826087, Blast_Score=64, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323482, Length=69, Percent_Identity=40.5797101449275, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324194, Length=69, Percent_Identity=44.9275362318841, Blast_Score=61, Evalue=6e-11,
Organism=Drosophila melanogaster, GI21356629, Length=65, Percent_Identity=47.6923076923077, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24655568, Length=69, Percent_Identity=46.3768115942029, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 15792; Mature: 15661

Theoretical pI: Translated: 4.31; Mature: 4.31

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEAKKGDTVKVHYTGRFEDGEIFDSSTGKEPLEFTIGKGEVIPGFEEAIIGMNTGESKT
CCCCCCCCEEEEEEECCCCCCCEECCCCCCCCEEEEECCCCCCCCHHHEEEECCCCCCCE
VKIPPEKAYGPRYDELVLTVERSRFPDDMEPQLGQQLQLRQPDGRTFIVTITDINETAVT
EECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCEEEE
LDANHPLAGKDLVFEINLIEIV
EECCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
PEAKKGDTVKVHYTGRFEDGEIFDSSTGKEPLEFTIGKGEVIPGFEEAIIGMNTGESKT
CCCCCCCEEEEEEECCCCCCCEECCCCCCCCEEEEECCCCCCCCHHHEEEECCCCCCCE
VKIPPEKAYGPRYDELVLTVERSRFPDDMEPQLGQQLQLRQPDGRTFIVTITDINETAVT
EECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCEEEEEEEECCCEEEE
LDANHPLAGKDLVFEINLIEIV
EECCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]