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The map label for this gene is yacO [H]

Identifier: 239617976

GI number: 239617976

Start: 1721065

End: 1721817

Strand: Reverse

Name: yacO [H]

Synonym: Kole_1604

Alternate gene names: 239617976

Gene position: 1721817-1721065 (Counterclockwise)

Preceding gene: 239617977

Following gene: 239617975

Centisome position: 74.79

GC content: 43.16

Gene sequence:

>753_bases
ATGTATCTTCATGGAAGAAATGTGCTGAGAGAGATTCTAAAACTTGAACCAAAAAAACTGAAAATAAAAAAGGTCCTCTT
TACGGATCAGAAAAATGTTGACAGGGAGCTCGAGGAGTTGAAAGAACATACAGCTAAAAAAGGTTACAGAATGGAAGTCG
TCCCTCCTGAAAAACTCTTCAACCTCTCCCGCGAAAAGAAACATCAGGGCGTTGTGATAAACCTCAAAGAATTCCCTTAC
ACCTCTTTAGAAACACTTCTAGATAAAATTATGGAAAAAAAGCGCTCCTTACTGGTTCTTCTGGATAGAATTCAAGACCC
TCACAATCTTGGAGCGATAATTCGAAGTTCTGTAGCCGCCGGTGCCGATGGCGTAATCATAACGGAAAAGGCGTCGGTAG
AGGTAACACCGGCTGTGGTAAAAGTTTCCACAGGCCTGGTTTTCAGGATTCCTATCGTTCGCGTGGTCAACATGGCGCGA
ACAATTGAAACCTTAAAGGAAGAGGGATTTTGGACTTATGCTGCTACAATGGAAGGAGAGCCTTACTACTCGGTGAGTTT
CACTGACAAAGCCGCTTTGATCTTTGGTAACGAAGGCAAAGGGATAAGACACCTGGTTAAAAAGAAAAGTGATTACCTCG
TTTCTATCCCAATGTGTGAGGGTATCGACTCGCTGAATGTTGCCGCTTCAGCAGCAATAATGCTTTTCGAGTATCGAAGG
CAATGGGCTTTGAGAGAAGGTGTGAATCCATGA

Upstream 100 bases:

>100_bases
AACTATAAATGTGCTACCGCCCTGGAAGCCCTCGTTGGGTATCTCTTTTTGAAAGGCCGGTATCGTCGTCTGGAGGAACT
TCTGGAAAAGGTGGAAAATG

Downstream 100 bases:

>100_bases
AAATACATGAATTACCTCAGGAAGTGATTTTGAAGATCGCGGCAGGTGAGGTTGTTACCGGTTGTTTCTCAGTGGTAAAG
GAGCTTGTGGAAAACGCTCT

Product: RNA methyltransferase, TrmH family, group 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MYLHGRNVLREILKLEPKKLKIKKVLFTDQKNVDRELEELKEHTAKKGYRMEVVPPEKLFNLSREKKHQGVVINLKEFPY
TSLETLLDKIMEKKRSLLVLLDRIQDPHNLGAIIRSSVAAGADGVIITEKASVEVTPAVVKVSTGLVFRIPIVRVVNMAR
TIETLKEEGFWTYAATMEGEPYYSVSFTDKAALIFGNEGKGIRHLVKKKSDYLVSIPMCEGIDSLNVAASAAIMLFEYRR
QWALREGVNP

Sequences:

>Translated_250_residues
MYLHGRNVLREILKLEPKKLKIKKVLFTDQKNVDRELEELKEHTAKKGYRMEVVPPEKLFNLSREKKHQGVVINLKEFPY
TSLETLLDKIMEKKRSLLVLLDRIQDPHNLGAIIRSSVAAGADGVIITEKASVEVTPAVVKVSTGLVFRIPIVRVVNMAR
TIETLKEEGFWTYAATMEGEPYYSVSFTDKAALIFGNEGKGIRHLVKKKSDYLVSIPMCEGIDSLNVAASAAIMLFEYRR
QWALREGVNP
>Mature_250_residues
MYLHGRNVLREILKLEPKKLKIKKVLFTDQKNVDRELEELKEHTAKKGYRMEVVPPEKLFNLSREKKHQGVVINLKEFPY
TSLETLLDKIMEKKRSLLVLLDRIQDPHNLGAIIRSSVAAGADGVIITEKASVEVTPAVVKVSTGLVFRIPIVRVVNMAR
TIETLKEEGFWTYAATMEGEPYYSVSFTDKAALIFGNEGKGIRHLVKKKSDYLVSIPMCEGIDSLNVAASAAIMLFEYRR
QWALREGVNP

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=203, Percent_Identity=28.0788177339901, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1790623, Length=240, Percent_Identity=31.6666666666667, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1788935, Length=241, Percent_Identity=23.2365145228216, Blast_Score=71, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17555908, Length=227, Percent_Identity=23.3480176211454, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324775, Length=184, Percent_Identity=32.0652173913043, Blast_Score=83, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 28355; Mature: 28355

Theoretical pI: Translated: 9.92; Mature: 9.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLHGRNVLREILKLEPKKLKIKKVLFTDQKNVDRELEELKEHTAKKGYRMEVVPPEKLF
CCCCHHHHHHHHHHCCCCCEEEEHHEECCCCCHHHHHHHHHHHHHHCCCEEEECCHHHHH
NLSREKKHQGVVINLKEFPYTSLETLLDKIMEKKRSLLVLLDRIQDPHNLGAIIRSSVAA
CCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
GADGVIITEKASVEVTPAVVKVSTGLVFRIPIVRVVNMARTIETLKEEGFWTYAATMEGE
CCCCEEEEECCCEEECCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
PYYSVSFTDKAALIFGNEGKGIRHLVKKKSDYLVSIPMCEGIDSLNVAASAAIMLFEYRR
CEEEEEECCCEEEEECCCCCHHHHHHHCCCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHH
QWALREGVNP
HHHHHCCCCC
>Mature Secondary Structure
MYLHGRNVLREILKLEPKKLKIKKVLFTDQKNVDRELEELKEHTAKKGYRMEVVPPEKLF
CCCCHHHHHHHHHHCCCCCEEEEHHEECCCCCHHHHHHHHHHHHHHCCCEEEECCHHHHH
NLSREKKHQGVVINLKEFPYTSLETLLDKIMEKKRSLLVLLDRIQDPHNLGAIIRSSVAA
CCCHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
GADGVIITEKASVEVTPAVVKVSTGLVFRIPIVRVVNMARTIETLKEEGFWTYAATMEGE
CCCCEEEEECCCEEECCEEEEEECCEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEECCC
PYYSVSFTDKAALIFGNEGKGIRHLVKKKSDYLVSIPMCEGIDSLNVAASAAIMLFEYRR
CEEEEEECCCEEEEECCCCCHHHHHHHCCCCCEEEEHHHCCCCCHHHHHHHHHHHHHHHH
QWALREGVNP
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]