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The map label for this gene is appB [H]

Identifier: 239617921

GI number: 239617921

Start: 1660580

End: 1661614

Strand: Reverse

Name: appB [H]

Synonym: Kole_1549

Alternate gene names: 239617921

Gene position: 1661614-1660580 (Counterclockwise)

Preceding gene: 239617922

Following gene: 239617920

Centisome position: 72.18

GC content: 47.15

Gene sequence:

>1035_bases
GTGACCGCGTACATCATAAGAAGGTTGCTTTTGCTTCCTTTGATTCTAATTGGTGTAACACTCATCATTTTCGCGATGAT
CTGGGCCCTGGGCCCCGAACGTCTTCTCGCATCTTACGTTAAGAGCCCAGAAGCCTTAAAAACCCCTGATGCCGCCCAGA
GGTTAATCCGCAAATACGGGCTCGATCAGCCAATGCCTGTAATGTACGCTAAATGGCTCTGGAATGTTGTAAGAGGCGAT
ATGGGCTATTCCCTTGTCGGGAAAGAACCGGTTGCAAAAGCGATAGCTGAAAGATTCACTTACACCTTTGAACTGGCTAT
ATACGCCTTTATTCCGGTAGTCCTTGTAGCAATCTCTCTGGGGGTGATTTCAGCAGTAAACCACAACAAATTCATAGACC
AATTTATAAGGGTATTCGCCCTTATAGGTTGGTCTCTCCCGGATTTTGTTTTCGGGTTGCTGCTACTGTGGATTTTCTAT
GCGAAACTGGGGTGGTTCCCACCAGGCATGGTAAGCCCGGAATATGACCTTGTTATGCGAAGCGCCGAATGGCACACAAT
AACCCATATGCCAACCTTTGATGCACTGCTCAATGGGCGTTTTGACGTCTTTTTGGATGCTCTGAGGCATATGATCCTTC
CGGTGATCACCCTGGCATATCTCTGGTGGGCGTATCTGTTGAGAATAACCCGTTCCAGTATGCTTGAGGTACTGAGAAAG
GATTACATAAGAACTGCAAGGGCAAAGGGGGTTCCAGAAAAAATAGTCATAAACAAGCACGCCAAAAGAAACGCCCTCAT
TCCCGTTGTTACCGTCGCGGGAGGTACAGTCATAGGATTACTTTCCGGAACTGTTATCATAGAGTCAGTTTACAGCAGAT
CCGGAATCGGCCGCTTCCTCGCTGATGCAGCTACTCAATTGGATTACTGGTCTATCATCGGTGGTGCGTTGTTCTTCTCA
TTCTTGCTAGTCATCGGTAACTTAATCGTCGACGTAAGCTACGCAATCATCGATCCCAGAATCAGGTTACAGTGA

Upstream 100 bases:

>100_bases
TTTGTTAACCCTGGCCTCTTTTATCTTTTTCTTTCCTCATGTATAATTTAATTAGTTTCTTAAATCTCAAATTTTTTTAT
GCCGAAGGAGTGATACACAG

Downstream 100 bases:

>100_bases
GGGGGTTGTGCTGATGTCTGAAAGAAAGAGAAAAAGTGATTTTCAAAAGATGATGAAGAAATTCTGGACCAACGGGACAG
CCGTTCTTGGCGCATCTCTG

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTAYIIRRLLLLPLILIGVTLIIFAMIWALGPERLLASYVKSPEALKTPDAAQRLIRKYGLDQPMPVMYAKWLWNVVRGD
MGYSLVGKEPVAKAIAERFTYTFELAIYAFIPVVLVAISLGVISAVNHNKFIDQFIRVFALIGWSLPDFVFGLLLLWIFY
AKLGWFPPGMVSPEYDLVMRSAEWHTITHMPTFDALLNGRFDVFLDALRHMILPVITLAYLWWAYLLRITRSSMLEVLRK
DYIRTARAKGVPEKIVINKHAKRNALIPVVTVAGGTVIGLLSGTVIIESVYSRSGIGRFLADAATQLDYWSIIGGALFFS
FLLVIGNLIVDVSYAIIDPRIRLQ

Sequences:

>Translated_344_residues
MTAYIIRRLLLLPLILIGVTLIIFAMIWALGPERLLASYVKSPEALKTPDAAQRLIRKYGLDQPMPVMYAKWLWNVVRGD
MGYSLVGKEPVAKAIAERFTYTFELAIYAFIPVVLVAISLGVISAVNHNKFIDQFIRVFALIGWSLPDFVFGLLLLWIFY
AKLGWFPPGMVSPEYDLVMRSAEWHTITHMPTFDALLNGRFDVFLDALRHMILPVITLAYLWWAYLLRITRSSMLEVLRK
DYIRTARAKGVPEKIVINKHAKRNALIPVVTVAGGTVIGLLSGTVIIESVYSRSGIGRFLADAATQLDYWSIIGGALFFS
FLLVIGNLIVDVSYAIIDPRIRLQ
>Mature_343_residues
TAYIIRRLLLLPLILIGVTLIIFAMIWALGPERLLASYVKSPEALKTPDAAQRLIRKYGLDQPMPVMYAKWLWNVVRGDM
GYSLVGKEPVAKAIAERFTYTFELAIYAFIPVVLVAISLGVISAVNHNKFIDQFIRVFALIGWSLPDFVFGLLLLWIFYA
KLGWFPPGMVSPEYDLVMRSAEWHTITHMPTFDALLNGRFDVFLDALRHMILPVITLAYLWWAYLLRITRSSMLEVLRKD
YIRTARAKGVPEKIVINKHAKRNALIPVVTVAGGTVIGLLSGTVIIESVYSRSGIGRFLADAATQLDYWSIIGGALFFSF
LLVIGNLIVDVSYAIIDPRIRLQ

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=343, Percent_Identity=37.9008746355685, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787053, Length=346, Percent_Identity=36.1271676300578, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1787497, Length=344, Percent_Identity=32.8488372093023, Blast_Score=164, Evalue=9e-42,
Organism=Escherichia coli, GI1787761, Length=342, Percent_Identity=37.4269005847953, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1789888, Length=342, Percent_Identity=30.4093567251462, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787550, Length=271, Percent_Identity=34.3173431734317, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788504, Length=301, Percent_Identity=30.5647840531561, Blast_Score=140, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 38807; Mature: 38676

Theoretical pI: Translated: 10.04; Mature: 10.04

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAYIIRRLLLLPLILIGVTLIIFAMIWALGPERLLASYVKSPEALKTPDAAQRLIRKYG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
LDQPMPVMYAKWLWNVVRGDMGYSLVGKEPVAKAIAERFTYTFELAIYAFIPVVLVAISL
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVISAVNHNKFIDQFIRVFALIGWSLPDFVFGLLLLWIFYAKLGWFPPGMVSPEYDLVMR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEE
SAEWHTITHMPTFDALLNGRFDVFLDALRHMILPVITLAYLWWAYLLRITRSSMLEVLRK
CCCCCEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYIRTARAKGVPEKIVINKHAKRNALIPVVTVAGGTVIGLLSGTVIIESVYSRSGIGRFL
HHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHH
ADAATQLDYWSIIGGALFFSFLLVIGNLIVDVSYAIIDPRIRLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TAYIIRRLLLLPLILIGVTLIIFAMIWALGPERLLASYVKSPEALKTPDAAQRLIRKYG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
LDQPMPVMYAKWLWNVVRGDMGYSLVGKEPVAKAIAERFTYTFELAIYAFIPVVLVAISL
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVISAVNHNKFIDQFIRVFALIGWSLPDFVFGLLLLWIFYAKLGWFPPGMVSPEYDLVMR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEE
SAEWHTITHMPTFDALLNGRFDVFLDALRHMILPVITLAYLWWAYLLRITRSSMLEVLRK
CCCCCEEECCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DYIRTARAKGVPEKIVINKHAKRNALIPVVTVAGGTVIGLLSGTVIIESVYSRSGIGRFL
HHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHHHH
ADAATQLDYWSIIGGALFFSFLLVIGNLIVDVSYAIIDPRIRLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]