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The map label for this gene is dppA [H]

Identifier: 239617922

GI number: 239617922

Start: 1661754

End: 1663592

Strand: Reverse

Name: dppA [H]

Synonym: Kole_1550

Alternate gene names: 239617922

Gene position: 1663592-1661754 (Counterclockwise)

Preceding gene: 239617923

Following gene: 239617921

Centisome position: 72.26

GC content: 47.91

Gene sequence:

>1839_bases
GTGAGGAAAGCATTTTTGCTTACACTCGCAGTTCTTTTGGTTGCGATCGTCGGTCTCGCCGAAGTCAAGAATCCCGACAC
ATTCATTACACTGACCATCGGTGAGCCTGAAACGCTCGATCCACATTATTGTTATGAAACCGCTGGCGGAGGAGTCATCC
TTAACGTTTATGATAACCTTATAAAGTACAAAGGTGACTCAGTTACTGAATTTGAACCCATGATCGCCACGGAAGTACCG
TCTATCGAAAACGGTCTCATTCAGGATGGCGGTACAAAGTACATATTCCCGATAAGAAAAGGCATCAAGTTCCACACAGG
TAGAGAACTCACACCTTACGATGTCGAGTACAGTTTTGAAAGAGGTATCCTCTTTGATCCTGCTGGAGGACCAATGTGGA
TGATCATCGAGGCCCTTTCCGGTGGGGATTACCAGTGTCTCGAAGACTGGTTCGAGGCTTACGCTGGCATGCCCTACTCC
GAGGCTGTAGATGAGAATAGAGAACCAACCTCTGAAGAGGCAAAGGCAAAGCTCATCGCTTTCTACAACGAAGTCATCGA
TCCTCTGGTTGAGGTCGAAGGCGATAACGTTATATTTACACTTCACGCTCCATTTGCACCGTTCATGTGGATAATCTCCC
ACTATGCCGGTTGGAGCGCCGTTCTTGATTCTGAATGGGCAAAGGCCAACGGTACCTGGGACGGAAATGCCGACGGTTGG
TGGAAATGGCATGACCTCCAGCCTGAAGAAACCCCACTGCATTCTGCTGAAGCCGGTTCCGGTCCATTCAAGCTCGTCGA
ATGGGATCGTGCACAACAGAAGGTTATCCTCGAAAGATATGACGAATACTGGAGAGGTCCCGCCAAGCTAAAGACAGTCA
TCATCTGGGGTATCGACGAATACTCCACCAGAAAAGCCATGCTTGAGGCTGGAGACGCTGATATGGTCTATGTCCCTGCA
CAATACAGGGATCAGGTTATAAATCTCCCCGGTGTCAGGGTTATTGAAGGATACCCAACATCCGTCATCGCTTCCCTCCA
CTTTAACTGGGAAGTCAGGGAAGGCAGTGAATACGTCGGAAGCGGAAAACTCGACGGAAATGGTATACCGCTTAACTTCT
TCAGCGATGTGCATGTTAGAAAGGCATTTGCATACTGTTACAATGGTGAAGTATTCATAAACGAGGTTCTCAATGGACTC
GGTAAGCTTGTTCCGACCGACCTCCCCGAAGGCTACTTAGGATTCGATCCTACGCTTCCGGTGCCCGAGTTCAACTTGCA
AAAAGCCACTGAAGAATTCAAGAAAGCCTTCAACGGAGAACTCTGGAAGAAAGGGTTCAAACTCACACTTCTTTACAACA
CCGGTAACGAAGCCAGACAAACAGCCGCTGAAATGCTGAAATTCTTCATCGAATCCATCAATCCTAAGTTCAAGATTGAG
GTTCAGGGTGTCCAGTGGCCGACCTACCTGAAGGCTCAGAGAGCGGGTTACATGCCTGCATTCATAATCGGATGGCTTGC
CGACTATCCTGATCCACACAACTTCATAGCGACCTACTACTCCACGAAGGGTGTTTACGCTTCCAGACAGGGTAAACCCT
TCCTTGAATTCGCTGAAAAATACCTGGATCCTCTCATATTCCAGGCTGTTAAGGAGATCGATCCGAAGAAACGTGAAGAA
CTCTACATAAAAGTTCAGAAGATCGTTATCGAAAATGCTGTTGGTGTTCCTCTCTACATGCCTCTCGGATTCCACGTAGA
GAGAACCTGGGTCAAAGGCTGGTATCCACATCCGTTGAGATCTGGTGCCAATTACTACGAACTCTCCAAGGAAGAATAA

Upstream 100 bases:

>100_bases
GTAAAGAGCAAGATGATCATCATCATGAAGTTTTGAATTTGAAGGACAATGCGATATAATACCTATGGTGTCAATCAACT
TTGTATAAGGGGGTGTTGTT

Downstream 100 bases:

>100_bases
TAAGCAAATCTTCAAGTAATTTCACTTTAGAGGCCAGGGTTTGTTAACCCTGGCCTCTTTTATCTTTTTCTTTCCTCATG
TATAATTTAATTAGTTTCTT

Product: extracellular solute-binding protein family 5

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 612; Mature: 612

Protein sequence:

>612_residues
MRKAFLLTLAVLLVAIVGLAEVKNPDTFITLTIGEPETLDPHYCYETAGGGVILNVYDNLIKYKGDSVTEFEPMIATEVP
SIENGLIQDGGTKYIFPIRKGIKFHTGRELTPYDVEYSFERGILFDPAGGPMWMIIEALSGGDYQCLEDWFEAYAGMPYS
EAVDENREPTSEEAKAKLIAFYNEVIDPLVEVEGDNVIFTLHAPFAPFMWIISHYAGWSAVLDSEWAKANGTWDGNADGW
WKWHDLQPEETPLHSAEAGSGPFKLVEWDRAQQKVILERYDEYWRGPAKLKTVIIWGIDEYSTRKAMLEAGDADMVYVPA
QYRDQVINLPGVRVIEGYPTSVIASLHFNWEVREGSEYVGSGKLDGNGIPLNFFSDVHVRKAFAYCYNGEVFINEVLNGL
GKLVPTDLPEGYLGFDPTLPVPEFNLQKATEEFKKAFNGELWKKGFKLTLLYNTGNEARQTAAEMLKFFIESINPKFKIE
VQGVQWPTYLKAQRAGYMPAFIIGWLADYPDPHNFIATYYSTKGVYASRQGKPFLEFAEKYLDPLIFQAVKEIDPKKREE
LYIKVQKIVIENAVGVPLYMPLGFHVERTWVKGWYPHPLRSGANYYELSKEE

Sequences:

>Translated_612_residues
MRKAFLLTLAVLLVAIVGLAEVKNPDTFITLTIGEPETLDPHYCYETAGGGVILNVYDNLIKYKGDSVTEFEPMIATEVP
SIENGLIQDGGTKYIFPIRKGIKFHTGRELTPYDVEYSFERGILFDPAGGPMWMIIEALSGGDYQCLEDWFEAYAGMPYS
EAVDENREPTSEEAKAKLIAFYNEVIDPLVEVEGDNVIFTLHAPFAPFMWIISHYAGWSAVLDSEWAKANGTWDGNADGW
WKWHDLQPEETPLHSAEAGSGPFKLVEWDRAQQKVILERYDEYWRGPAKLKTVIIWGIDEYSTRKAMLEAGDADMVYVPA
QYRDQVINLPGVRVIEGYPTSVIASLHFNWEVREGSEYVGSGKLDGNGIPLNFFSDVHVRKAFAYCYNGEVFINEVLNGL
GKLVPTDLPEGYLGFDPTLPVPEFNLQKATEEFKKAFNGELWKKGFKLTLLYNTGNEARQTAAEMLKFFIESINPKFKIE
VQGVQWPTYLKAQRAGYMPAFIIGWLADYPDPHNFIATYYSTKGVYASRQGKPFLEFAEKYLDPLIFQAVKEIDPKKREE
LYIKVQKIVIENAVGVPLYMPLGFHVERTWVKGWYPHPLRSGANYYELSKEE
>Mature_612_residues
MRKAFLLTLAVLLVAIVGLAEVKNPDTFITLTIGEPETLDPHYCYETAGGGVILNVYDNLIKYKGDSVTEFEPMIATEVP
SIENGLIQDGGTKYIFPIRKGIKFHTGRELTPYDVEYSFERGILFDPAGGPMWMIIEALSGGDYQCLEDWFEAYAGMPYS
EAVDENREPTSEEAKAKLIAFYNEVIDPLVEVEGDNVIFTLHAPFAPFMWIISHYAGWSAVLDSEWAKANGTWDGNADGW
WKWHDLQPEETPLHSAEAGSGPFKLVEWDRAQQKVILERYDEYWRGPAKLKTVIIWGIDEYSTRKAMLEAGDADMVYVPA
QYRDQVINLPGVRVIEGYPTSVIASLHFNWEVREGSEYVGSGKLDGNGIPLNFFSDVHVRKAFAYCYNGEVFINEVLNGL
GKLVPTDLPEGYLGFDPTLPVPEFNLQKATEEFKKAFNGELWKKGFKLTLLYNTGNEARQTAAEMLKFFIESINPKFKIE
VQGVQWPTYLKAQRAGYMPAFIIGWLADYPDPHNFIATYYSTKGVYASRQGKPFLEFAEKYLDPLIFQAVKEIDPKKREE
LYIKVQKIVIENAVGVPLYMPLGFHVERTWVKGWYPHPLRSGANYYELSKEE

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=630, Percent_Identity=25.3968253968254, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI1787762, Length=598, Percent_Identity=23.9130434782609, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI87081878, Length=609, Percent_Identity=21.0180623973727, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787551, Length=583, Percent_Identity=21.0977701543739, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787495, Length=232, Percent_Identity=25, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 69495; Mature: 69495

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKAFLLTLAVLLVAIVGLAEVKNPDTFITLTIGEPETLDPHYCYETAGGGVILNVYDNL
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHEECCCCCEEEEEHHHH
IKYKGDSVTEFEPMIATEVPSIENGLIQDGGTKYIFPIRKGIKFHTGRELTPYDVEYSFE
HHCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCCCCCCCEEEEC
RGILFDPAGGPMWMIIEALSGGDYQCLEDWFEAYAGMPYSEAVDENREPTSEEAKAKLIA
CCEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHH
FYNEVIDPLVEVEGDNVIFTLHAPFAPFMWIISHYAGWSAVLDSEWAKANGTWDGNADGW
HHHHHHHHHHEECCCCEEEEEECCHHHHHHHHHHHCCHHHHHCCCHHCCCCCCCCCCCCE
WKWHDLQPEETPLHSAEAGSGPFKLVEWDRAQQKVILERYDEYWRGPAKLKTVIIWGIDE
EEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
YSTRKAMLEAGDADMVYVPAQYRDQVINLPGVRVIEGYPTSVIASLHFNWEVREGSEYVG
HHHHHHHHHCCCCCEEEECHHHHHHEECCCCEEEECCCCCEEEEEEEEEEEECCCCCCCC
SGKLDGNGIPLNFFSDVHVRKAFAYCYNGEVFINEVLNGLGKLVPTDLPEGYLGFDPTLP
CCCCCCCCCCEECCCCHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VPEFNLQKATEEFKKAFNGELWKKGFKLTLLYNTGNEARQTAAEMLKFFIESINPKFKIE
CCCCCHHHHHHHHHHHHCCHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEE
VQGVQWPTYLKAQRAGYMPAFIIGWLADYPDPHNFIATYYSTKGVYASRQGKPFLEFAEK
EECCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCEEECCCCCHHHHHHHH
YLDPLIFQAVKEIDPKKREELYIKVQKIVIENAVGVPLYMPLGFHVERTWVKGWYPHPLR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEHEECCCCCCHHH
SGANYYELSKEE
CCCCEEECCCCC
>Mature Secondary Structure
MRKAFLLTLAVLLVAIVGLAEVKNPDTFITLTIGEPETLDPHYCYETAGGGVILNVYDNL
CCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCHHEECCCCCEEEEEHHHH
IKYKGDSVTEFEPMIATEVPSIENGLIQDGGTKYIFPIRKGIKFHTGRELTPYDVEYSFE
HHCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEECCCCEECCCCCCCCCCCEEEEC
RGILFDPAGGPMWMIIEALSGGDYQCLEDWFEAYAGMPYSEAVDENREPTSEEAKAKLIA
CCEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHH
FYNEVIDPLVEVEGDNVIFTLHAPFAPFMWIISHYAGWSAVLDSEWAKANGTWDGNADGW
HHHHHHHHHHEECCCCEEEEEECCHHHHHHHHHHHCCHHHHHCCCHHCCCCCCCCCCCCE
WKWHDLQPEETPLHSAEAGSGPFKLVEWDRAQQKVILERYDEYWRGPAKLKTVIIWGIDE
EEECCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCC
YSTRKAMLEAGDADMVYVPAQYRDQVINLPGVRVIEGYPTSVIASLHFNWEVREGSEYVG
HHHHHHHHHCCCCCEEEECHHHHHHEECCCCEEEECCCCCEEEEEEEEEEEECCCCCCCC
SGKLDGNGIPLNFFSDVHVRKAFAYCYNGEVFINEVLNGLGKLVPTDLPEGYLGFDPTLP
CCCCCCCCCCEECCCCHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCC
VPEFNLQKATEEFKKAFNGELWKKGFKLTLLYNTGNEARQTAAEMLKFFIESINPKFKIE
CCCCCHHHHHHHHHHHHCCHHHHCCEEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEE
VQGVQWPTYLKAQRAGYMPAFIIGWLADYPDPHNFIATYYSTKGVYASRQGKPFLEFAEK
EECCCCCHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCEEECCCCCHHHHHHHH
YLDPLIFQAVKEIDPKKREELYIKVQKIVIENAVGVPLYMPLGFHVERTWVKGWYPHPLR
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEHEECCCCCCHHH
SGANYYELSKEE
CCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]