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The map label for this gene is appC [H]

Identifier: 239617920

GI number: 239617920

Start: 1659682

End: 1660566

Strand: Reverse

Name: appC [H]

Synonym: Kole_1548

Alternate gene names: 239617920

Gene position: 1660566-1659682 (Counterclockwise)

Preceding gene: 239617921

Following gene: 239617919

Centisome position: 72.13

GC content: 47.68

Gene sequence:

>885_bases
ATGTCTGAAAGAAAGAGAAAAAGTGATTTTCAAAAGATGATGAAGAAATTCTGGACCAACGGGACAGCCGTTCTTGGCGC
ATCTCTGCTCATATTCTTCATAATCGTGGCTATCTTCGCTCCCAAAATCGCTGGGACCAATCCAACAGGTGATAATTACC
AGATGCCCCGGGTTGCGTGGACATCGCGACCCATCGCACCAAGTTCCGAACATCCCTTCGGGGTGATCGGTGGAAGAGAT
ATTTTCTATGGAGTCGTCTGGGGAACGCGCACTGCTTTTAGACTCGGCCTCACCGTTGCCGGTCTGGCAACCCTTATCGG
TATCTTCGTTGGTTCGATTTCAGCATATTTTGGAGGCTGGGTTGATGAAATATTGATGAGAATCGTTGATATATTCATGT
CAATCCCCTTCCTGGTTGCCGCAATGGTTCTGACAACTATACTCGGAAAAGGTCTGGATAAAGTGATGGTAGCACTTGTC
GCTTTTGGTTGGATGGCCACCGCCAGGCTCATAAGGGGTAACATCCTTCAGGCACGTGAAGAACAATATGTCCTTGCCGC
ACGCGCTCTCGGCCAAAAGGATTGGCTGATTATCGTTAAACATATTCTCCCGAATACTATTTTTCCGGTCGTCGTTCAGA
TGTCAATGAGAATGGGATCATACGTTATTACTGCCGCTGCACTCAGCTTCCTTGGTGTTGGTGCTGAACCTGGCTACGCA
GATTGGGGTACCATACTGAGTTATTCCAGAAACTGGATGACCATGTTAGACCAATCATGGTTTGCAATTGTGTTCCCCGG
TATCGCCATGGTCTTATTCGTTCTCGCGTGGAACCTTGTTGGCGATGCTTTGAGAGACATCTTCGACCCGAGATTGAGAA
GTTAA

Upstream 100 bases:

>100_bases
TTGTTCTTCTCATTCTTGCTAGTCATCGGTAACTTAATCGTCGACGTAAGCTACGCAATCATCGATCCCAGAATCAGGTT
ACAGTGAGGGGGTTGTGCTG

Downstream 100 bases:

>100_bases
GGGGGTTCAAAAGTGGAGAAAAAACCTGTTCTCGAAGTGAAAAATCTAAGAACCTATTTCCATACAGATGACGGTATCGT
TAAAGCCGTTGACGGAGTCA

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSERKRKSDFQKMMKKFWTNGTAVLGASLLIFFIIVAIFAPKIAGTNPTGDNYQMPRVAWTSRPIAPSSEHPFGVIGGRD
IFYGVVWGTRTAFRLGLTVAGLATLIGIFVGSISAYFGGWVDEILMRIVDIFMSIPFLVAAMVLTTILGKGLDKVMVALV
AFGWMATARLIRGNILQAREEQYVLAARALGQKDWLIIVKHILPNTIFPVVVQMSMRMGSYVITAAALSFLGVGAEPGYA
DWGTILSYSRNWMTMLDQSWFAIVFPGIAMVLFVLAWNLVGDALRDIFDPRLRS

Sequences:

>Translated_294_residues
MSERKRKSDFQKMMKKFWTNGTAVLGASLLIFFIIVAIFAPKIAGTNPTGDNYQMPRVAWTSRPIAPSSEHPFGVIGGRD
IFYGVVWGTRTAFRLGLTVAGLATLIGIFVGSISAYFGGWVDEILMRIVDIFMSIPFLVAAMVLTTILGKGLDKVMVALV
AFGWMATARLIRGNILQAREEQYVLAARALGQKDWLIIVKHILPNTIFPVVVQMSMRMGSYVITAAALSFLGVGAEPGYA
DWGTILSYSRNWMTMLDQSWFAIVFPGIAMVLFVLAWNLVGDALRDIFDPRLRS
>Mature_293_residues
SERKRKSDFQKMMKKFWTNGTAVLGASLLIFFIIVAIFAPKIAGTNPTGDNYQMPRVAWTSRPIAPSSEHPFGVIGGRDI
FYGVVWGTRTAFRLGLTVAGLATLIGIFVGSISAYFGGWVDEILMRIVDIFMSIPFLVAAMVLTTILGKGLDKVMVALVA
FGWMATARLIRGNILQAREEQYVLAARALGQKDWLIIVKHILPNTIFPVVVQMSMRMGSYVITAAALSFLGVGAEPGYAD
WGTILSYSRNWMTMLDQSWFAIVFPGIAMVLFVLAWNLVGDALRDIFDPRLRS

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=288, Percent_Identity=35.4166666666667, Blast_Score=181, Evalue=6e-47,
Organism=Escherichia coli, GI1787760, Length=290, Percent_Identity=35.1724137931034, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789964, Length=288, Percent_Identity=34.375, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789889, Length=234, Percent_Identity=32.4786324786325, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787498, Length=294, Percent_Identity=30.952380952381, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1788505, Length=230, Percent_Identity=29.5652173913043, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787549, Length=296, Percent_Identity=25.3378378378378, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32500; Mature: 32369

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSERKRKSDFQKMMKKFWTNGTAVLGASLLIFFIIVAIFAPKIAGTNPTGDNYQMPRVAW
CCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
TSRPIAPSSEHPFGVIGGRDIFYGVVWGTRTAFRLGLTVAGLATLIGIFVGSISAYFGGW
CCCCCCCCCCCCEEEECCCHHHEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDEILMRIVDIFMSIPFLVAAMVLTTILGKGLDKVMVALVAFGWMATARLIRGNILQARE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQYVLAARALGQKDWLIIVKHILPNTIFPVVVQMSMRMGSYVITAAALSFLGVGAEPGYA
HHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DWGTILSYSRNWMTMLDQSWFAIVFPGIAMVLFVLAWNLVGDALRDIFDPRLRS
HHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SERKRKSDFQKMMKKFWTNGTAVLGASLLIFFIIVAIFAPKIAGTNPTGDNYQMPRVAW
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEE
TSRPIAPSSEHPFGVIGGRDIFYGVVWGTRTAFRLGLTVAGLATLIGIFVGSISAYFGGW
CCCCCCCCCCCCEEEECCCHHHEEHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDEILMRIVDIFMSIPFLVAAMVLTTILGKGLDKVMVALVAFGWMATARLIRGNILQARE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQYVLAARALGQKDWLIIVKHILPNTIFPVVVQMSMRMGSYVITAAALSFLGVGAEPGYA
HHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
DWGTILSYSRNWMTMLDQSWFAIVFPGIAMVLFVLAWNLVGDALRDIFDPRLRS
HHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]