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The map label for this gene is argD [H]

Identifier: 239616507

GI number: 239616507

Start: 111948

End: 113147

Strand: Direct

Name: argD [H]

Synonym: Kole_0097

Alternate gene names: 239616507

Gene position: 111948-113147 (Clockwise)

Preceding gene: 239616506

Following gene: 239616508

Centisome position: 4.86

GC content: 40.33

Gene sequence:

>1200_bases
ATGAATGGTATGAATTATCTGATGAATACCTACAATAGATTTCCTGTGGTATTTGATCACGGTGAAGGTGCCCGGATCTG
GGATAAAAATGGAAAATCTTACCTTGATTTCACATCAGGAATAGCGGTTAATGTGCTTGGCCATTCACACCCAAAGCTCG
TAGAAACGATAAAAACTCAAGCTGAAAAGTTGATCCACTGTTCGAATTTATACTGGACAGAACCACAAATTGAGCTTGCA
AAGCTGTTAGGAGAAAATACTTTGAAGGGGAAAGTATTCTTTGTGAACAGCGGTACAGAAGCCAACGAAACCGCAATTAA
GATTGCACGAAAATACGGAAAGAAAAAGGATAAAAATAAGTATAAGATTCTATCTGCCCATGATTCTTTCCATGGAAGAA
CTTTAGGGTCGTTGACAGCAACGGGACAACCAAAATACCAGGAAGATTTCAAACCTCTTGTTGATGGCTTCGATTATTTT
GAATTCAACAACATCGATTCCCTGAAACAGAAGATATCTAATGAAGTGTGTGCTGTGATTTTAGAGCCCGTTCAAGGGGA
AAGTGGGATCATTCCAGCTACAAAAGATTTCTTAGAAGCTGTAAGAAAATTGTGCAATGAATATGAAACGCTTTTGATTT
TCGATGAAGTGCAATGTGGAATGGGAAGAACCGGGAAACTCTTTGCCTACCAAAGATACGGTGTAGATCCAGATATTCTA
ACGGTTGCGAAAGGACTAGGCGGTGGTGTCCCGATCGGAGCGGTTGTTGTGAATAAAAAAGCTGATATTCTGGAACCCGG
CGACCACGGCTCAACATTCGGAGGAAATCCACTCGCTTGCAGTGCAGGAGTAACCGTTATGAGAGAGATACTGGAAAATA
ATCTTCTTGAACAAGTGGAAAAACTGGGAATTTATTTGAAGAAAAAACTCGAAAACCTGAAAGAAAAATTTCCAGAACAC
GTGAAAGAGACGAGAGGTATAGGGTTAATGCTGGGAATGGAACTGAAGGAAATTTCTGCAAAAGATTTTGCAAAAAAGTG
TTTTGAGAAAGGATTGTTACTTGTTCCAGCAGGAAACAACACTGTGAGATTCTTACCACCGTTCGTTATCACGGAAGACG
ATATAGATCAAGCTCTGGAAATCGTTAAAGAATGTTTTAGCGAGTTCGAGAACCGAGAATCGAGATCCGAGACCCGGTAA

Upstream 100 bases:

>100_bases
GCGTTCACATAATAAATGGTGGGGTGGAACATGCCTTACTACTCGAGATTTTCAGCAAAGAAGGAATTGGAACTATGATA
AAGAACCTGGAGGTGTGAGA

Downstream 100 bases:

>100_bases
GCACGACTTCGTTGCAGGTGAGCCCGGCTTCGCCGGGGGTACGCCCAGAAAAATCGACACGCGATTTTTCTGGCGGTGCA
AACTGCTTCGTAGTTGTTAT

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNGMNYLMNTYNRFPVVFDHGEGARIWDKNGKSYLDFTSGIAVNVLGHSHPKLVETIKTQAEKLIHCSNLYWTEPQIELA
KLLGENTLKGKVFFVNSGTEANETAIKIARKYGKKKDKNKYKILSAHDSFHGRTLGSLTATGQPKYQEDFKPLVDGFDYF
EFNNIDSLKQKISNEVCAVILEPVQGESGIIPATKDFLEAVRKLCNEYETLLIFDEVQCGMGRTGKLFAYQRYGVDPDIL
TVAKGLGGGVPIGAVVVNKKADILEPGDHGSTFGGNPLACSAGVTVMREILENNLLEQVEKLGIYLKKKLENLKEKFPEH
VKETRGIGLMLGMELKEISAKDFAKKCFEKGLLLVPAGNNTVRFLPPFVITEDDIDQALEIVKECFSEFENRESRSETR

Sequences:

>Translated_399_residues
MNGMNYLMNTYNRFPVVFDHGEGARIWDKNGKSYLDFTSGIAVNVLGHSHPKLVETIKTQAEKLIHCSNLYWTEPQIELA
KLLGENTLKGKVFFVNSGTEANETAIKIARKYGKKKDKNKYKILSAHDSFHGRTLGSLTATGQPKYQEDFKPLVDGFDYF
EFNNIDSLKQKISNEVCAVILEPVQGESGIIPATKDFLEAVRKLCNEYETLLIFDEVQCGMGRTGKLFAYQRYGVDPDIL
TVAKGLGGGVPIGAVVVNKKADILEPGDHGSTFGGNPLACSAGVTVMREILENNLLEQVEKLGIYLKKKLENLKEKFPEH
VKETRGIGLMLGMELKEISAKDFAKKCFEKGLLLVPAGNNTVRFLPPFVITEDDIDQALEIVKECFSEFENRESRSETR
>Mature_399_residues
MNGMNYLMNTYNRFPVVFDHGEGARIWDKNGKSYLDFTSGIAVNVLGHSHPKLVETIKTQAEKLIHCSNLYWTEPQIELA
KLLGENTLKGKVFFVNSGTEANETAIKIARKYGKKKDKNKYKILSAHDSFHGRTLGSLTATGQPKYQEDFKPLVDGFDYF
EFNNIDSLKQKISNEVCAVILEPVQGESGIIPATKDFLEAVRKLCNEYETLLIFDEVQCGMGRTGKLFAYQRYGVDPDIL
TVAKGLGGGVPIGAVVVNKKADILEPGDHGSTFGGNPLACSAGVTVMREILENNLLEQVEKLGIYLKKKLENLKEKFPEH
VKETRGIGLMLGMELKEISAKDFAKKCFEKGLLLVPAGNNTVRFLPPFVITEDDIDQALEIVKECFSEFENRESRSETR

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=393, Percent_Identity=35.6234096692112, Blast_Score=258, Evalue=7e-69,
Organism=Homo sapiens, GI284507298, Length=304, Percent_Identity=37.171052631579, Blast_Score=211, Evalue=1e-54,
Organism=Homo sapiens, GI13994255, Length=450, Percent_Identity=30.6666666666667, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI37574042, Length=423, Percent_Identity=29.3144208037825, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI226442709, Length=392, Percent_Identity=29.5918367346939, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24119277, Length=426, Percent_Identity=26.056338028169, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI226442705, Length=423, Percent_Identity=28.6052009456265, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI188536080, Length=448, Percent_Identity=23.6607142857143, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI38679950, Length=448, Percent_Identity=23.6607142857143, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI38679946, Length=448, Percent_Identity=23.6607142857143, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1789759, Length=365, Percent_Identity=44.3835616438356, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1788044, Length=394, Percent_Identity=41.1167512690355, Blast_Score=330, Evalue=1e-91,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=37.0843989769821, Blast_Score=246, Evalue=2e-66,
Organism=Escherichia coli, GI1789016, Length=406, Percent_Identity=35.2216748768473, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI1787560, Length=399, Percent_Identity=33.0827067669173, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1786349, Length=320, Percent_Identity=30, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1786991, Length=412, Percent_Identity=28.1553398058252, Blast_Score=137, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25144271, Length=391, Percent_Identity=33.2480818414322, Blast_Score=233, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=439, Percent_Identity=31.6628701594533, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI25144274, Length=296, Percent_Identity=32.7702702702703, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=417, Percent_Identity=30.4556354916067, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17541228, Length=435, Percent_Identity=25.2873563218391, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71981843, Length=164, Percent_Identity=30.4878048780488, Blast_Score=95, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6324432, Length=391, Percent_Identity=40.920716112532, Blast_Score=300, Evalue=3e-82,
Organism=Saccharomyces cerevisiae, GI6323470, Length=406, Percent_Identity=33.9901477832512, Blast_Score=231, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6324386, Length=453, Percent_Identity=29.3598233995585, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6321456, Length=359, Percent_Identity=28.133704735376, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21357415, Length=390, Percent_Identity=36.6666666666667, Blast_Score=261, Evalue=8e-70,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=30.6122448979592, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI28574759, Length=433, Percent_Identity=30.715935334873, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21356575, Length=425, Percent_Identity=27.0588235294118, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI281366494, Length=413, Percent_Identity=26.3922518159806, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24667139, Length=413, Percent_Identity=26.3922518159806, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24667143, Length=413, Percent_Identity=26.3922518159806, Blast_Score=99, Evalue=4e-21,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 44544; Mature: 44544

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS00600 AA_TRANSFER_CLASS_3 ; PS00878 ODR_DC_2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGMNYLMNTYNRFPVVFDHGEGARIWDKNGKSYLDFTSGIAVNVLGHSHPKLVETIKTQ
CCCHHHHHHHHCCCCEEEECCCCCEEECCCCCEEEEECCCCEEEECCCCCHHHHHHHHHH
AEKLIHCSNLYWTEPQIELAKLLGENTLKGKVFFVNSGTEANETAIKIARKYGKKKDKNK
HHHHHHHCCCEECCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
YKILSAHDSFHGRTLGSLTATGQPKYQEDFKPLVDGFDYFEFNNIDSLKQKISNEVCAVI
EEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEHH
LEPVQGESGIIPATKDFLEAVRKLCNEYETLLIFDEVQCGMGRTGKLFAYQRYGVDPDIL
EECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCEEEEEECCCCHHHH
TVAKGLGGGVPIGAVVVNKKADILEPGDHGSTFGGNPLACSAGVTVMREILENNLLEQVE
HHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KLGIYLKKKLENLKEKFPEHVKETRGIGLMLGMELKEISAKDFAKKCFEKGLLLVPAGNN
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCEEEEECCCC
TVRFLPPFVITEDDIDQALEIVKECFSEFENRESRSETR
EEEECCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MNGMNYLMNTYNRFPVVFDHGEGARIWDKNGKSYLDFTSGIAVNVLGHSHPKLVETIKTQ
CCCHHHHHHHHCCCCEEEECCCCCEEECCCCCEEEEECCCCEEEECCCCCHHHHHHHHHH
AEKLIHCSNLYWTEPQIELAKLLGENTLKGKVFFVNSGTEANETAIKIARKYGKKKDKNK
HHHHHHHCCCEECCCHHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCC
YKILSAHDSFHGRTLGSLTATGQPKYQEDFKPLVDGFDYFEFNNIDSLKQKISNEVCAVI
EEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEHH
LEPVQGESGIIPATKDFLEAVRKLCNEYETLLIFDEVQCGMGRTGKLFAYQRYGVDPDIL
EECCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEECHHCCCCCCCCEEEEEECCCCHHHH
TVAKGLGGGVPIGAVVVNKKADILEPGDHGSTFGGNPLACSAGVTVMREILENNLLEQVE
HHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
KLGIYLKKKLENLKEKFPEHVKETRGIGLMLGMELKEISAKDFAKKCFEKGLLLVPAGNN
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCEEEEECCCC
TVRFLPPFVITEDDIDQALEIVKECFSEFENRESRSETR
EEEECCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]