Click here to switch to the map view.

The map label for this gene is argB

Identifier: 239616506

GI number: 239616506

Start: 111097

End: 111945

Strand: Direct

Name: argB

Synonym: Kole_0096

Alternate gene names: 239616506

Gene position: 111097-111945 (Clockwise)

Preceding gene: 239616505

Following gene: 239616507

Centisome position: 4.83

GC content: 39.69

Gene sequence:

>849_bases
GTGAAGCGTGAAACTGTTCAGGTACTCCTTGAAGCGCTTCCATACATAAAGGAATTCCACGGAAAAACCTTTGTGATAAA
GTTCGGTGGAAGTGCCATGAAAAATGAAAATGCAAAAGAAGCGTTCATAAAGGATCTGGTTCTTTTAAAATACACCGGCA
TAAATCCCGTAATAGTTCATGGCGGTGGTTCTGAAATAAGCAGTCTCATGAACCAACTTGGAATAGAACCAGTTTTCAAA
AACGGGTACAGGATCACCGATGAGAAAACAATGGAAATAGTCGAGATGGTACTCGTTGGGAAGGTTAATAAAGACATAGT
CATGAATATAAATCTTCATGGTGGAAAAGCGATCGGTGTATGTGGCAAAGATGGTGAGCTTCTACTTGCAGAGAAAGAAA
CGAAATATGGGGATATAGGTTATGTTGGAAAAGTAAAAAAAGTGGATACCACTCTAATAAAAGGGCTTCTGGTGGAAGGC
TACATTCCTGTGATAGCTCCCATTGGCTTTGGAGAAGATGGGACTTCGTACAACATCAATGCAGATATTGTCGCTGCTGA
AATAGCAAAAAGTTTGGAAGTTGAAAAATTGGTTCTTCTGACAGATGTAGATGGTGTTTTTAAAGATGGAAAGTTGTTAC
CCATTCTATCATCAAAAGAAGCTGAGGATTTAATCGAAAAAAATATTGTGAAAGGCGGCATGATTCCAAAACTCCAGTGT
GCAATCTCAGCTGTGAACAGCGGTGTCAAAAGCGTTCACATAATAAATGGTGGGGTGGAACATGCCTTACTACTCGAGAT
TTTCAGCAAAGAAGGAATTGGAACTATGATAAAGAACCTGGAGGTGTGA

Upstream 100 bases:

>100_bases
TAAGATTGATACTCGACATGAAACAGGGTAATGGTGAAGCAACAGCCTGGGGAAGCGATCTGACTGAAAAATATGTGGAG
ATAAACGGGAGGTACAGAAC

Downstream 100 bases:

>100_bases
GAATGAATGGTATGAATTATCTGATGAATACCTACAATAGATTTCCTGTGGTATTTGATCACGGTGAAGGTGCCCGGATC
TGGGATAAAAATGGAAAATC

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MKRETVQVLLEALPYIKEFHGKTFVIKFGGSAMKNENAKEAFIKDLVLLKYTGINPVIVHGGGSEISSLMNQLGIEPVFK
NGYRITDEKTMEIVEMVLVGKVNKDIVMNINLHGGKAIGVCGKDGELLLAEKETKYGDIGYVGKVKKVDTTLIKGLLVEG
YIPVIAPIGFGEDGTSYNINADIVAAEIAKSLEVEKLVLLTDVDGVFKDGKLLPILSSKEAEDLIEKNIVKGGMIPKLQC
AISAVNSGVKSVHIINGGVEHALLLEIFSKEGIGTMIKNLEV

Sequences:

>Translated_282_residues
MKRETVQVLLEALPYIKEFHGKTFVIKFGGSAMKNENAKEAFIKDLVLLKYTGINPVIVHGGGSEISSLMNQLGIEPVFK
NGYRITDEKTMEIVEMVLVGKVNKDIVMNINLHGGKAIGVCGKDGELLLAEKETKYGDIGYVGKVKKVDTTLIKGLLVEG
YIPVIAPIGFGEDGTSYNINADIVAAEIAKSLEVEKLVLLTDVDGVFKDGKLLPILSSKEAEDLIEKNIVKGGMIPKLQC
AISAVNSGVKSVHIINGGVEHALLLEIFSKEGIGTMIKNLEV
>Mature_282_residues
MKRETVQVLLEALPYIKEFHGKTFVIKFGGSAMKNENAKEAFIKDLVLLKYTGINPVIVHGGGSEISSLMNQLGIEPVFK
NGYRITDEKTMEIVEMVLVGKVNKDIVMNINLHGGKAIGVCGKDGELLLAEKETKYGDIGYVGKVKKVDTTLIKGLLVEG
YIPVIAPIGFGEDGTSYNINADIVAAEIAKSLEVEKLVLLTDVDGVFKDGKLLPILSSKEAEDLIEKNIVKGGMIPKLQC
AISAVNSGVKSVHIINGGVEHALLLEIFSKEGIGTMIKNLEV

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=289, Percent_Identity=30.7958477508651, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI145693208, Length=258, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320913, Length=283, Percent_Identity=29.6819787985866, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_KOSOT (C5CHW9)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002939828.1
- GeneID:   7967514
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_0096
- ProtClustDB:   PRK00942
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 30436; Mature: 30436

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: NA

Important sites: BINDING 84-84 BINDING 178-178

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRETVQVLLEALPYIKEFHGKTFVIKFGGSAMKNENAKEAFIKDLVLLKYTGINPVIVH
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHEEEECCCCEEEEE
GGGSEISSLMNQLGIEPVFKNGYRITDEKTMEIVEMVLVGKVNKDIVMNINLHGGKAIGV
CCCHHHHHHHHHHCCCEECCCCEEECCHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEE
CGKDGELLLAEKETKYGDIGYVGKVKKVDTTLIKGLLVEGYIPVIAPIGFGEDGTSYNIN
ECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECC
ADIVAAEIAKSLEVEKLVLLTDVDGVFKDGKLLPILSSKEAEDLIEKNIVKGGMIPKLQC
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHH
AISAVNSGVKSVHIINGGVEHALLLEIFSKEGIGTMIKNLEV
HHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MKRETVQVLLEALPYIKEFHGKTFVIKFGGSAMKNENAKEAFIKDLVLLKYTGINPVIVH
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHEEEECCCCEEEEE
GGGSEISSLMNQLGIEPVFKNGYRITDEKTMEIVEMVLVGKVNKDIVMNINLHGGKAIGV
CCCHHHHHHHHHHCCCEECCCCEEECCHHHHHHHHHHHHCCCCCCEEEEEEECCCCEEEE
CGKDGELLLAEKETKYGDIGYVGKVKKVDTTLIKGLLVEGYIPVIAPIGFGEDGTSYNIN
ECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEECC
ADIVAAEIAKSLEVEKLVLLTDVDGVFKDGKLLPILSSKEAEDLIEKNIVKGGMIPKLQC
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHH
AISAVNSGVKSVHIINGGVEHALLLEIFSKEGIGTMIKNLEV
HHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA