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The map label for this gene is ddl [H]

Identifier: 238925027

GI number: 238925027

Start: 2556876

End: 2557874

Strand: Direct

Name: ddl [H]

Synonym: EUBREC_2678

Alternate gene names: 238925027

Gene position: 2556876-2557874 (Clockwise)

Preceding gene: 238925026

Following gene: 238925030

Centisome position: 74.12

GC content: 28.73

Gene sequence:

>999_bases
ATGAAATTTTTGATTATATGTGATTATCGCGAAAATTTTGTTGATTATTCCCGAGCTAATACAAATAAAATGTATAATGA
TCATCCGAGCCAAAAAAATATAACGGAAATAATGGATGCAATCAAATCCTTGGGATACAATTGTGATTATTTCGGAGGTA
TTCCTGAATTGATTCACGCAATTGATACAAATCAAAGCTTTGATGATAGTATTTTTTTAAATTTTTCAGATGGAATGGAT
GAGGATTATAGCCGTATACAGGCTCCTGCATTATTAGAGATATTAAATGTTCCATATAGTGGTTCAGGTGTGTTCCCATC
TGCATTAATGAATAATAAGCACTTTTGTAAAAAAGCATTACTAAACTTAGGAATCAGAATGCCTAAATCTTGTATTGTAA
ATCATGATTTTCCACTTAATTGTGCTCAATTAAGAAAATGGAAATATCCTTTATTTGTAAAACCAAATTGTGAAGGCTCA
TCTTTGGGTATTTCGAATGACTGTGTTTGCCATACAATTGATGAAGTAATCAAAAAATGTAACAAATTGCTCATGGACTT
TCAAGAAATTATCATAGAAGAATATGTTGAAGGTATTGATGTAACAAATTATTTGATTGGAAATAATGCTTCATATTATA
TAAATAGCATTGTTACCGCTAAATTATTTGATGAATCTTCTTATGCAATTTATGGTATTAACGAAAAACAAAATAAACTT
AGAACTTTGTTTATAGATGATGAATATATTCCAACTAATTTAGTTGAGGCTATTAAAAGGCAATCAATTTTAATAGCCCA
AACATTAGGTGTTCATGATATATGCCGTATTGATTATCGTGTGAATGTTTCAAAACAAGAATTTGATTTTATTGAAATAA
ACTCCGCACCACGTTTCAGTAGCACAAGTGAAATTGGATTTATTGCACAAAAAAACAATATTCTATTTTCTAAAATGGTT
CAATATTATTTAACTACTGTTCTTGATCGATTAACATGA

Upstream 100 bases:

>100_bases
ATCACTAAGTTGGTGGATTGTAATTGATGGATAATAGATGATTATCTTTCATGTTACGTACTATTTTCTTTTTTAACAAA
CTAATTACGAAAGGTTTTTT

Downstream 100 bases:

>100_bases
ATTAATCATGCGCGTACACTAAAAACCAAGGTTCGAAGTACAATGTATTTGAACATTGTTCCTTGGGGCGTGGTATCGGA
TTATTATTCGAGTTATTATT

Product: D-ala D-alanine ligase

Products: NA

Alternate protein names: D-Ala-D-Ala ligase; D-alanylalanine synthetase [H]

Number of amino acids: Translated: 332; Mature: 332

Protein sequence:

>332_residues
MKFLIICDYRENFVDYSRANTNKMYNDHPSQKNITEIMDAIKSLGYNCDYFGGIPELIHAIDTNQSFDDSIFLNFSDGMD
EDYSRIQAPALLEILNVPYSGSGVFPSALMNNKHFCKKALLNLGIRMPKSCIVNHDFPLNCAQLRKWKYPLFVKPNCEGS
SLGISNDCVCHTIDEVIKKCNKLLMDFQEIIIEEYVEGIDVTNYLIGNNASYYINSIVTAKLFDESSYAIYGINEKQNKL
RTLFIDDEYIPTNLVEAIKRQSILIAQTLGVHDICRIDYRVNVSKQEFDFIEINSAPRFSSTSEIGFIAQKNNILFSKMV
QYYLTTVLDRLT

Sequences:

>Translated_332_residues
MKFLIICDYRENFVDYSRANTNKMYNDHPSQKNITEIMDAIKSLGYNCDYFGGIPELIHAIDTNQSFDDSIFLNFSDGMD
EDYSRIQAPALLEILNVPYSGSGVFPSALMNNKHFCKKALLNLGIRMPKSCIVNHDFPLNCAQLRKWKYPLFVKPNCEGS
SLGISNDCVCHTIDEVIKKCNKLLMDFQEIIIEEYVEGIDVTNYLIGNNASYYINSIVTAKLFDESSYAIYGINEKQNKL
RTLFIDDEYIPTNLVEAIKRQSILIAQTLGVHDICRIDYRVNVSKQEFDFIEINSAPRFSSTSEIGFIAQKNNILFSKMV
QYYLTTVLDRLT
>Mature_332_residues
MKFLIICDYRENFVDYSRANTNKMYNDHPSQKNITEIMDAIKSLGYNCDYFGGIPELIHAIDTNQSFDDSIFLNFSDGMD
EDYSRIQAPALLEILNVPYSGSGVFPSALMNNKHFCKKALLNLGIRMPKSCIVNHDFPLNCAQLRKWKYPLFVKPNCEGS
SLGISNDCVCHTIDEVIKKCNKLLMDFQEIIIEEYVEGIDVTNYLIGNNASYYINSIVTAKLFDESSYAIYGINEKQNKL
RTLFIDDEYIPTNLVEAIKRQSILIAQTLGVHDICRIDYRVNVSKQEFDFIEINSAPRFSSTSEIGFIAQKNNILFSKMV
QYYLTTVLDRLT

Specific function: Cell wall formation [H]

COG id: COG1181

COG function: function code M; D-alanine-D-alanine ligase and related ATP-grasp enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR000291
- InterPro:   IPR005905
- InterPro:   IPR011095
- InterPro:   IPR011127
- InterPro:   IPR013817
- InterPro:   IPR016185 [H]

Pfam domain/function: PF07478 Dala_Dala_lig_C; PF01820 Dala_Dala_lig_N [H]

EC number: =6.3.2.4 [H]

Molecular weight: Translated: 38046; Mature: 38046

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFLIICDYRENFVDYSRANTNKMYNDHPSQKNITEIMDAIKSLGYNCDYFGGIPELIHA
CEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHH
IDTNQSFDDSIFLNFSDGMDEDYSRIQAPALLEILNVPYSGSGVFPSALMNNKHFCKKAL
HCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHH
LNLGIRMPKSCIVNHDFPLNCAQLRKWKYPLFVKPNCEGSSLGISNDCVCHTIDEVIKKC
HHCCCCCCHHHEECCCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
NKLLMDFQEIIIEEYVEGIDVTNYLIGNNASYYINSIVTAKLFDESSYAIYGINEKQNKL
HHHHHHHHHHHHHHHHCCCCHHHEEECCCCCEEHHHHEEEEEECCCCEEEEECCCCCCCE
RTLFIDDEYIPTNLVEAIKRQSILIAQTLGVHDICRIDYRVNVSKQEFDFIEINSAPRFS
EEEEECCCCCCHHHHHHHHHCCEEEEHHCCCHHEEEEEEEECCCCCCCCEEEECCCCCCC
STSEIGFIAQKNNILFSKMVQYYLTTVLDRLT
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFLIICDYRENFVDYSRANTNKMYNDHPSQKNITEIMDAIKSLGYNCDYFGGIPELIHA
CEEEEEECCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHH
IDTNQSFDDSIFLNFSDGMDEDYSRIQAPALLEILNVPYSGSGVFPSALMNNKHFCKKAL
HCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHH
LNLGIRMPKSCIVNHDFPLNCAQLRKWKYPLFVKPNCEGSSLGISNDCVCHTIDEVIKKC
HHCCCCCCHHHEECCCCCCCHHHHHHCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHH
NKLLMDFQEIIIEEYVEGIDVTNYLIGNNASYYINSIVTAKLFDESSYAIYGINEKQNKL
HHHHHHHHHHHHHHHHCCCCHHHEEECCCCCEEHHHHEEEEEECCCCEEEEECCCCCCCE
RTLFIDDEYIPTNLVEAIKRQSILIAQTLGVHDICRIDYRVNVSKQEFDFIEINSAPRFS
EEEEECCCCCCHHHHHHHHHCCEEEEHHCCCHHEEEEEEEECCCCCCCCEEEECCCCCCC
STSEIGFIAQKNNILFSKMVQYYLTTVLDRLT
CCCCEEEEEECCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]