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The map label for this gene is xerC

Identifier: 238925026

GI number: 238925026

Start: 2555841

End: 2556761

Strand: Direct

Name: xerC

Synonym: EUBREC_2677

Alternate gene names: 238925026

Gene position: 2555841-2556761 (Clockwise)

Preceding gene: 238925024

Following gene: 238925027

Centisome position: 74.09

GC content: 31.16

Gene sequence:

>921_bases
ATGAATAACTTACAAACACACATAAGCAGCTATTTAGAATACTGTCTGGCTCAAAAAAGGCTTGATGAAAAGACTATAAA
AGCCTACAGAATTGATCTTATTCAATTTTATAATGAAATATCAATATCAGACCCTTGTAAGATTGCATCCTATGATTTAG
AAAAATATATAGAAAAAATGCATCTAAAATACAAGCCGAAATCTGTCAGGCGGAAAATTGCATCAATTAAAGCTTTTTTT
CATTATTTAGAATACAAAAACATAATACTGCAAAATCCATTTAATAAAATACAAATTCATTTTCGAGAACCGGTAATCCT
CCCCAAAACAATCCCTCTCTATATAGTGGAAAAATTCTTATTTACTATATATAAACAACGTTCTGCCGCCAAAACTAATT
ATCAAAAAAGAAATGCCTTACGCGATGCTGCTATTGTTGAGCTGCTATTCTCCACAGGAATACGAATCTCAGAACTATGT
AATCTTAAAATCAGTGATGTAAACCTAATTGATGGTGTCATCTTAATATACGGAAAAGGAAGCAAAGAAAGAATTCTGCA
AATTGGAAATAGTTCCGTACTTAATATTTTGAAAGAATATAAAAACGACTTCTACAATGAAATCGTACAGTGTAATCACT
TTTTTTCCAGTCAATCCGGAAAACCATTATCAGATCAGTCTGTTCGTCGAATGATAAATAAATATGCCTCTCTCTCATCT
ATTGATTTACATATAACACCTCATATGTTCAGACACACTTTCGCCACAAGCCTTCTAGAAGCTGATGTTGATATTCGGTA
TATTCAAGAAATGCTTGGGCATAGTTCAATTAATATCACTCAAATCTATACTCATGTAGCAGTCTCAAAGCAAAAAGATA
TTCTAATAAACAAACATCCTAGAAAAGATTTTCATTTTTAA

Upstream 100 bases:

>100_bases
ATAGTACCGCTTTTTTAATAAAAGTAAACATTCTTTATGTCAATATAATTATAATAGTATAATAATCACTAATATCAAAT
TATCAAAAGGAGATTCTACT

Downstream 100 bases:

>100_bases
TTATTATACAATCCATCACTAAGTTGGTGGATTGTAATTGATGGATAATAGATGATTATCTTTCATGTTACGTACTATTT
TCTTTTTTAACAAACTAATT

Product: integrase/recombinase-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MNNLQTHISSYLEYCLAQKRLDEKTIKAYRIDLIQFYNEISISDPCKIASYDLEKYIEKMHLKYKPKSVRRKIASIKAFF
HYLEYKNIILQNPFNKIQIHFREPVILPKTIPLYIVEKFLFTIYKQRSAAKTNYQKRNALRDAAIVELLFSTGIRISELC
NLKISDVNLIDGVILIYGKGSKERILQIGNSSVLNILKEYKNDFYNEIVQCNHFFSSQSGKPLSDQSVRRMINKYASLSS
IDLHITPHMFRHTFATSLLEADVDIRYIQEMLGHSSINITQIYTHVAVSKQKDILINKHPRKDFHF

Sequences:

>Translated_306_residues
MNNLQTHISSYLEYCLAQKRLDEKTIKAYRIDLIQFYNEISISDPCKIASYDLEKYIEKMHLKYKPKSVRRKIASIKAFF
HYLEYKNIILQNPFNKIQIHFREPVILPKTIPLYIVEKFLFTIYKQRSAAKTNYQKRNALRDAAIVELLFSTGIRISELC
NLKISDVNLIDGVILIYGKGSKERILQIGNSSVLNILKEYKNDFYNEIVQCNHFFSSQSGKPLSDQSVRRMINKYASLSS
IDLHITPHMFRHTFATSLLEADVDIRYIQEMLGHSSINITQIYTHVAVSKQKDILINKHPRKDFHF
>Mature_306_residues
MNNLQTHISSYLEYCLAQKRLDEKTIKAYRIDLIQFYNEISISDPCKIASYDLEKYIEKMHLKYKPKSVRRKIASIKAFF
HYLEYKNIILQNPFNKIQIHFREPVILPKTIPLYIVEKFLFTIYKQRSAAKTNYQKRNALRDAAIVELLFSTGIRISELC
NLKISDVNLIDGVILIYGKGSKERILQIGNSSVLNILKEYKNDFYNEIVQCNHFFSSQSGKPLSDQSVRRMINKYASLSS
IDLHITPHMFRHTFATSLLEADVDIRYIQEMLGHSSINITQIYTHVAVSKQKDILINKHPRKDFHF

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily

Homologues:

Organism=Escherichia coli, GI1789261, Length=301, Percent_Identity=32.2259136212625, Blast_Score=151, Evalue=6e-38,
Organism=Escherichia coli, GI1790244, Length=307, Percent_Identity=28.3387622149837, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790767, Length=155, Percent_Identity=30.9677419354839, Blast_Score=71, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XERC_EUBR3 (C4ZGY6)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002938542.1
- GeneID:   7964860
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_2677
- ProtClustDB:   CLSK2507693
- GO:   GO:0005737
- HAMAP:   MF_01808
- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- Gene3D:   G3DSA:1.10.150.130
- Gene3D:   G3DSA:1.10.443.10

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase; SSF56349 DNA_brk_join_enz; SSF47823 L_intgrse_like_N

EC number: NA

Molecular weight: Translated: 35862; Mature: 35862

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: ACT_SITE 155-155 ACT_SITE 179-179 ACT_SITE 248-248 ACT_SITE 251-251 ACT_SITE 274-274 ACT_SITE 283-283

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLQTHISSYLEYCLAQKRLDEKTIKAYRIDLIQFYNEISISDPCKIASYDLEKYIEKM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
HLKYKPKSVRRKIASIKAFFHYLEYKNIILQNPFNKIQIHFREPVILPKTIPLYIVEKFL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEECCCCHHHHHHHHHH
FTIYKQRSAAKTNYQKRNALRDAAIVELLFSTGIRISELCNLKISDVNLIDGVILIYGKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEECCEEEECCEEEEEECC
SKERILQIGNSSVLNILKEYKNDFYNEIVQCNHFFSSQSGKPLSDQSVRRMINKYASLSS
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
IDLHITPHMFRHTFATSLLEADVDIRYIQEMLGHSSINITQIYTHVAVSKQKDILINKHP
EEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECCCC
RKDFHF
CCCCCC
>Mature Secondary Structure
MNNLQTHISSYLEYCLAQKRLDEKTIKAYRIDLIQFYNEISISDPCKIASYDLEKYIEKM
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
HLKYKPKSVRRKIASIKAFFHYLEYKNIILQNPFNKIQIHFREPVILPKTIPLYIVEKFL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEECCCCHHHHHHHHHH
FTIYKQRSAAKTNYQKRNALRDAAIVELLFSTGIRISELCNLKISDVNLIDGVILIYGKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCEECCEEEECCEEEEEECC
SKERILQIGNSSVLNILKEYKNDFYNEIVQCNHFFSSQSGKPLSDQSVRRMINKYASLSS
CHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCC
IDLHITPHMFRHTFATSLLEADVDIRYIQEMLGHSSINITQIYTHVAVSKQKDILINKHP
EEEEECHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCEEECCCC
RKDFHF
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA