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The map label for this gene is yfjD [H]

Identifier: 238924896

GI number: 238924896

Start: 2420107

End: 2421276

Strand: Direct

Name: yfjD [H]

Synonym: EUBREC_2547

Alternate gene names: 238924896

Gene position: 2420107-2421276 (Clockwise)

Preceding gene: 238924894

Following gene: 238924910

Centisome position: 70.15

GC content: 44.44

Gene sequence:

>1170_bases
ATGAGAACCCTGGCTGAGGCTGGCAACACAAAAGCCAAAAAGGTGCTCAAGGTGACTGAGAACTCTCCAAAGATGCTCTC
AGCCATCCTTATCGGCAACAACATCGTAAATCTTTCAGCATCATCGCTCACCACCTCGCTTGCCATCAAGCTGTTTGGCA
GCGTCGGAGCAGGTGTCGCAACCGGAATACTTACATTCCTCATACTGATCTTCGGAGAGGTCTCTCCGAAGACACTTGCG
ACCATAAAGGCTGACAAGATTTCACTCTCAATCGCAGGCTTTATATCAGTGCTCATGGTAGTGCTGACACCTGTAATATT
TATCATCAACAAGCTTTCACTCGGGGTCATTTTCCTCTTTGGAATAAGACAGAGCGATGCCAAACGCGTCATGACCGAGG
AGGAGCTTCGTACAATCGTTGATGTAGGACAGGAGGACGGTGTCATCGAGGATGAAGAGCGTGATATGATTCACAATGTA
TTCGATTTTGGAGATGCCGAGGCCAAGGAGGTCATGGTTCCGCGTATTGATATGACGTTTGTCCATGTTGATTCTACTTA
TGATGATTTGATTTCCATATTCAGAGAGGATAAATTCACCAGACTCCCTGTGTATGACGAAAGCACTGACAACGTAATCG
GTATCGTAAATGTGAAGGATCTGCTACTCCTTAAGGATGAGGATAAAGAGCATTTTTCCATCAAAAATATCATGCGTGAG
CCTTACTTTACATATGAGCACAAGAATACAGCGAATCTTTTTCTCGAGATGCGCGAATCATCTATATCGCTTGCCATTGT
CTTAGATGAATACGGTGTCACAGCCGGACTCATCACACTTGAGGATCTCTTAGAGGAGATAGTCGGTGAGATTCGTGATG
AATACGACTCTGACGAGCAGGATGATATCACAAGAATAAATGACTACGAATACATAGTTCTTGGCTCTGCAAATCTCGAG
GATGTAAGCGATGAGCTTGGTCTGCACCTCGAATCAGACGACTATGACACAATCGGCGGCTACTGCCTTGAAAAGCTTGA
CCACCTGCCTGAAAAAAATGAAATAATCATCACTGATGACAATATCCTTCTCCGCATAGAGGCTGTTGATAAAAACCGAA
TCGAAAAGGTCTATATCAAATTGCCAAAGCCTGCCGAAGAAGAGAATTAA

Upstream 100 bases:

>100_bases
TGACGACATATCGCAGATTATATTCTTATTAATACTATTAGCACTCTCCGCATTTTTTTCATCTTCGGAGACCGCTCTTA
CTACCGTAAACAAAATACGT

Downstream 100 bases:

>100_bases
ATTCAGGATCGTTTAACCAGCGGGAGTTCTCCATGAGACCTCCTGCTTTATTTTTGCTGTAATACAAATACCATTCTTCA
TACGCTAGTTATCCTCCATT

Product: putative hemolysin-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MRTLAEAGNTKAKKVLKVTENSPKMLSAILIGNNIVNLSASSLTTSLAIKLFGSVGAGVATGILTFLILIFGEVSPKTLA
TIKADKISLSIAGFISVLMVVLTPVIFIINKLSLGVIFLFGIRQSDAKRVMTEEELRTIVDVGQEDGVIEDEERDMIHNV
FDFGDAEAKEVMVPRIDMTFVHVDSTYDDLISIFREDKFTRLPVYDESTDNVIGIVNVKDLLLLKDEDKEHFSIKNIMRE
PYFTYEHKNTANLFLEMRESSISLAIVLDEYGVTAGLITLEDLLEEIVGEIRDEYDSDEQDDITRINDYEYIVLGSANLE
DVSDELGLHLESDDYDTIGGYCLEKLDHLPEKNEIIITDDNILLRIEAVDKNRIEKVYIKLPKPAEEEN

Sequences:

>Translated_389_residues
MRTLAEAGNTKAKKVLKVTENSPKMLSAILIGNNIVNLSASSLTTSLAIKLFGSVGAGVATGILTFLILIFGEVSPKTLA
TIKADKISLSIAGFISVLMVVLTPVIFIINKLSLGVIFLFGIRQSDAKRVMTEEELRTIVDVGQEDGVIEDEERDMIHNV
FDFGDAEAKEVMVPRIDMTFVHVDSTYDDLISIFREDKFTRLPVYDESTDNVIGIVNVKDLLLLKDEDKEHFSIKNIMRE
PYFTYEHKNTANLFLEMRESSISLAIVLDEYGVTAGLITLEDLLEEIVGEIRDEYDSDEQDDITRINDYEYIVLGSANLE
DVSDELGLHLESDDYDTIGGYCLEKLDHLPEKNEIIITDDNILLRIEAVDKNRIEKVYIKLPKPAEEEN
>Mature_389_residues
MRTLAEAGNTKAKKVLKVTENSPKMLSAILIGNNIVNLSASSLTTSLAIKLFGSVGAGVATGILTFLILIFGEVSPKTLA
TIKADKISLSIAGFISVLMVVLTPVIFIINKLSLGVIFLFGIRQSDAKRVMTEEELRTIVDVGQEDGVIEDEERDMIHNV
FDFGDAEAKEVMVPRIDMTFVHVDSTYDDLISIFREDKFTRLPVYDESTDNVIGIVNVKDLLLLKDEDKEHFSIKNIMRE
PYFTYEHKNTANLFLEMRESSISLAIVLDEYGVTAGLITLEDLLEEIVGEIRDEYDSDEQDDITRINDYEYIVLGSANLE
DVSDELGLHLESDDYDTIGGYCLEKLDHLPEKNEIIITDDNILLRIEAVDKNRIEKVYIKLPKPAEEEN

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=354, Percent_Identity=30.5084745762712, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI94681046, Length=313, Percent_Identity=26.517571884984, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI40068055, Length=313, Percent_Identity=24.9201277955272, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI40068053, Length=313, Percent_Identity=24.9201277955272, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI145693175, Length=354, Percent_Identity=30.225988700565, Blast_Score=198, Evalue=6e-52,
Organism=Escherichia coli, GI1786879, Length=250, Percent_Identity=34.8, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790664, Length=378, Percent_Identity=21.957671957672, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI87082033, Length=268, Percent_Identity=26.865671641791, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788119, Length=246, Percent_Identity=28.4552845528455, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71980512, Length=315, Percent_Identity=24.7619047619048, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17539402, Length=302, Percent_Identity=27.4834437086093, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324512, Length=314, Percent_Identity=25.4777070063694, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 43606; Mature: 43606

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTLAEAGNTKAKKVLKVTENSPKMLSAILIGNNIVNLSASSLTTSLAIKLFGSVGAGVA
CCCCHHCCCHHHHHEEEECCCCHHHEEEEEECCCEEEEEHHHHHHHHHHHHHHCCCCHHH
TGILTFLILIFGEVSPKTLATIKADKISLSIAGFISVLMVVLTPVIFIINKLSLGVIFLF
HHHHHHHHHHHCCCCCCEEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
GIRQSDAKRVMTEEELRTIVDVGQEDGVIEDEERDMIHNVFDFGDAEAKEVMVPRIDMTF
ECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHEECCEEEEEE
VHVDSTYDDLISIFREDKFTRLPVYDESTDNVIGIVNVKDLLLLKDEDKEHFSIKNIMRE
EEECCCHHHHHHHHHCCCCEECCCCCCCCCCEEEEEEHEEEEEEECCCCHHHHHHHHHHC
PYFTYEHKNTANLFLEMRESSISLAIVLDEYGVTAGLITLEDLLEEIVGEIRDEYDSDEQ
CCEEECCCCHHHHEEEEECCCEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCCCC
DDITRINDYEYIVLGSANLEDVSDELGLHLESDDYDTIGGYCLEKLDHLPEKNEIIITDD
CCCEEECCEEEEEEECCCHHHHHHHHCCEECCCCCCHHHHHHHHHHHCCCCCCEEEEECC
NILLRIEAVDKNRIEKVYIKLPKPAEEEN
CEEEEEEECCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MRTLAEAGNTKAKKVLKVTENSPKMLSAILIGNNIVNLSASSLTTSLAIKLFGSVGAGVA
CCCCHHCCCHHHHHEEEECCCCHHHEEEEEECCCEEEEEHHHHHHHHHHHHHHCCCCHHH
TGILTFLILIFGEVSPKTLATIKADKISLSIAGFISVLMVVLTPVIFIINKLSLGVIFLF
HHHHHHHHHHHCCCCCCEEEEEEECCEEEHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEE
GIRQSDAKRVMTEEELRTIVDVGQEDGVIEDEERDMIHNVFDFGDAEAKEVMVPRIDMTF
ECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCHHEECCEEEEEE
VHVDSTYDDLISIFREDKFTRLPVYDESTDNVIGIVNVKDLLLLKDEDKEHFSIKNIMRE
EEECCCHHHHHHHHHCCCCEECCCCCCCCCCEEEEEEHEEEEEEECCCCHHHHHHHHHHC
PYFTYEHKNTANLFLEMRESSISLAIVLDEYGVTAGLITLEDLLEEIVGEIRDEYDSDEQ
CCEEECCCCHHHHEEEEECCCEEEEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCCCCC
DDITRINDYEYIVLGSANLEDVSDELGLHLESDDYDTIGGYCLEKLDHLPEKNEIIITDD
CCCEEECCEEEEEEECCCHHHHHHHHCCEECCCCCCHHHHHHHHHHHCCCCCCEEEEECC
NILLRIEAVDKNRIEKVYIKLPKPAEEEN
CEEEEEEECCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 3045760 [H]