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The map label for this gene is tcp [H]

Identifier: 238921589

GI number: 238921589

Start: 3628372

End: 3629949

Strand: Reverse

Name: tcp [H]

Synonym: NT01EI_3742

Alternate gene names: 238921589

Gene position: 3629949-3628372 (Counterclockwise)

Preceding gene: 238921590

Following gene: 238921586

Centisome position: 95.22

GC content: 62.67

Gene sequence:

>1578_bases
ATGTTTAAAAACGTCAGGGTTATCACGGGAATTATCGTCTTATTGGCCATATTTATCCTGCTGCAGGGAGTTTCCGGGCG
TCTATTTTATATGGCGATCGCGCAGGATCGGGGTAACTTCTCGCAGTCACGGGCGCTGAGCTATCAGCAGGAGCAGTTGG
CCGATGGCTGGCAGACGCTGGTGATGACGCGAGTGACCATTAACCGTGTCGCGATTCGTTACCTGAAGCAGCAAAATGCC
GGGGTGGCACAGCTTGAAATCGGCTCGCTGCTGAATGCGGCGAATGCTTCGCTGGACAGCGCCGAAGGCTACTTCAAAAA
CTATCGTGCCGCGCCGCGGCTGCCTGGGCAGGACGCTGCGTTAGCGGCGGAGGTTGAGCATCGCTTCACGGCGTTGTATC
GCCTGCTGCGCGATTCATCGCACTACCTGCGCGCCGGCGACTATCCGGCTTACGGCAAGCTGGAGACCCAGGAGGCGCAG
GAGGCCATGGCGAAGATTTATGCCCAGTGGCGCGCCCAGAATCATGGCCTGTTGCAGCAGGGGATCGACGCCAACCAGCG
CAGCTTTGGGCGTATGGTGTGGACGTTGGCCGGGATCGCGCTGGCGGTTGTGCTGTTAATCATCCTGGCCGGGGTGGCGG
CGCGAGGGATCCTGCTGCGGCCGCTGGCCCAGCTGCACGCGCATTTGCGTCGTCTGACCGCCGGCGATCTGTCGGCGACG
CTGGCGGGCGGGCGCAACGAGCTGGGGAGCCTGGCGCACAGCATCAGTGAAATGCAGCAGGCGCTGATTTCGATCGTCGG
ACAGGTGCGCAACGGCGCCGATACACTGCTGCACGGCAGCAGTGACATTACCGTCGGCAATGCGGATCTATCGTCGCGTA
CCGAGCAGCAGGCGGCCGCTCTGGAGGAGACAGCGGCCAGCATGGAGCAGTTAACGGCTACGGTGCGCCAGAATGCCGAT
AACGCCCGCCAGGCCAGCCAGCTGGCCAGCAGCGCCTCTGCGACGGCGAATCAGGGCGGAGCGGTGGTCGGCCAGGTCGT
CACAGCGATGGACGAGATCGCCGACAGCTCACGTAAAATTGCCAGCATTACCGGGGTGATTGACTCTATTGCTTTCCAGA
CCAATATATTGGCGCTTAATGCGGCAGTAGAGTCGGCGCGCGCCGGAGAGCAGGGGCGAGGCTTTGCCGTGGTGGCCGGT
GAGGTGCGCAGTCTGGCTCAGCGCAGCGCCCAGGCGGCGCGTGAGATTCGTACGTTGATCGAGGATTCGGTACGGCGTAT
CGATACCGGCTCCCAGCAGGCGACGCAGGCAGGAGAGACGATGCAGTCGGTGGTTGGTGCTGCCCAGCGGGTCACCGGAA
TTATTGCCGAGATCGCGGCGGCCTCTGACGAACAGAGTCAGGGGATCGCTCAGGTAAGTCAGGCGGTGAGTGAGATGGAG
CAGGTGACCCAGCAGAACGCTGCGCTGGTGCAGCAGTCCGCCGCGTCCGCCACATCGCTGGAGGAGCGGGCCTGCAGCCT
GTCCCAGGCGGTTGCCCTATTTACATTGCCAGAGAGTCAGGCGTCGCGCCCGGCATAA

Upstream 100 bases:

>100_bases
GTCGAGCGTATATTTATGTGACTAATATCGCGAATTTTCCAACGCCCCTGCCGATATATCCTTATTAGATACATACCATT
AAAGCACTTAGGAAAACGGC

Downstream 100 bases:

>100_bases
GCGTGCCAACGCCATACGGGCCGGCGAGGGCTGGCCCGTAGCGTGACATCGGGTTAACGCATGGTAACAAACTCTTCAGA
GGCCGTCGGATGGATGGCCA

Product: methyl-accepting chemotaxis protein I

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MFKNVRVITGIIVLLAIFILLQGVSGRLFYMAIAQDRGNFSQSRALSYQQEQLADGWQTLVMTRVTINRVAIRYLKQQNA
GVAQLEIGSLLNAANASLDSAEGYFKNYRAAPRLPGQDAALAAEVEHRFTALYRLLRDSSHYLRAGDYPAYGKLETQEAQ
EAMAKIYAQWRAQNHGLLQQGIDANQRSFGRMVWTLAGIALAVVLLIILAGVAARGILLRPLAQLHAHLRRLTAGDLSAT
LAGGRNELGSLAHSISEMQQALISIVGQVRNGADTLLHGSSDITVGNADLSSRTEQQAAALEETAASMEQLTATVRQNAD
NARQASQLASSASATANQGGAVVGQVVTAMDEIADSSRKIASITGVIDSIAFQTNILALNAAVESARAGEQGRGFAVVAG
EVRSLAQRSAQAAREIRTLIEDSVRRIDTGSQQATQAGETMQSVVGAAQRVTGIIAEIAAASDEQSQGIAQVSQAVSEME
QVTQQNAALVQQSAASATSLEERACSLSQAVALFTLPESQASRPA

Sequences:

>Translated_525_residues
MFKNVRVITGIIVLLAIFILLQGVSGRLFYMAIAQDRGNFSQSRALSYQQEQLADGWQTLVMTRVTINRVAIRYLKQQNA
GVAQLEIGSLLNAANASLDSAEGYFKNYRAAPRLPGQDAALAAEVEHRFTALYRLLRDSSHYLRAGDYPAYGKLETQEAQ
EAMAKIYAQWRAQNHGLLQQGIDANQRSFGRMVWTLAGIALAVVLLIILAGVAARGILLRPLAQLHAHLRRLTAGDLSAT
LAGGRNELGSLAHSISEMQQALISIVGQVRNGADTLLHGSSDITVGNADLSSRTEQQAAALEETAASMEQLTATVRQNAD
NARQASQLASSASATANQGGAVVGQVVTAMDEIADSSRKIASITGVIDSIAFQTNILALNAAVESARAGEQGRGFAVVAG
EVRSLAQRSAQAAREIRTLIEDSVRRIDTGSQQATQAGETMQSVVGAAQRVTGIIAEIAAASDEQSQGIAQVSQAVSEME
QVTQQNAALVQQSAASATSLEERACSLSQAVALFTLPESQASRPA
>Mature_525_residues
MFKNVRVITGIIVLLAIFILLQGVSGRLFYMAIAQDRGNFSQSRALSYQQEQLADGWQTLVMTRVTINRVAIRYLKQQNA
GVAQLEIGSLLNAANASLDSAEGYFKNYRAAPRLPGQDAALAAEVEHRFTALYRLLRDSSHYLRAGDYPAYGKLETQEAQ
EAMAKIYAQWRAQNHGLLQQGIDANQRSFGRMVWTLAGIALAVVLLIILAGVAARGILLRPLAQLHAHLRRLTAGDLSAT
LAGGRNELGSLAHSISEMQQALISIVGQVRNGADTLLHGSSDITVGNADLSSRTEQQAAALEETAASMEQLTATVRQNAD
NARQASQLASSASATANQGGAVVGQVVTAMDEIADSSRKIASITGVIDSIAFQTNILALNAAVESARAGEQGRGFAVVAG
EVRSLAQRSAQAAREIRTLIEDSVRRIDTGSQQATQAGETMQSVVGAAQRVTGIIAEIAAASDEQSQGIAQVSQAVSEME
QVTQQNAALVQQSAASATSLEERACSLSQAVALFTLPESQASRPA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=521, Percent_Identity=49.9040307101727, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1788195, Length=538, Percent_Identity=50.5576208178439, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1787690, Length=432, Percent_Identity=48.8425925925926, Blast_Score=343, Evalue=1e-95,
Organism=Escherichia coli, GI1788194, Length=530, Percent_Identity=41.3207547169811, Blast_Score=339, Evalue=3e-94,
Organism=Escherichia coli, GI1789453, Length=509, Percent_Identity=32.6129666011788, Blast_Score=221, Evalue=1e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 55707; Mature: 55707

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50885 HAMP ; PS00538 CHEMOTAXIS_TRANSDUC_1 ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNVRVITGIIVLLAIFILLQGVSGRLFYMAIAQDRGNFSQSRALSYQQEQLADGWQTL
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
VMTRVTINRVAIRYLKQQNAGVAQLEIGSLLNAANASLDSAEGYFKNYRAAPRLPGQDAA
HHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHH
LAAEVEHRFTALYRLLRDSSHYLRAGDYPAYGKLETQEAQEAMAKIYAQWRAQNHGLLQQ
HHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
GIDANQRSFGRMVWTLAGIALAVVLLIILAGVAARGILLRPLAQLHAHLRRLTAGDLSAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LAGGRNELGSLAHSISEMQQALISIVGQVRNGADTLLHGSSDITVGNADLSSRTEQQAAA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCCCEECCCCHHHHHHHHHHH
LEETAASMEQLTATVRQNADNARQASQLASSASATANQGGAVVGQVVTAMDEIADSSRKI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
ASITGVIDSIAFQTNILALNAAVESARAGEQGRGFAVVAGEVRSLAQRSAQAAREIRTLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
EDSVRRIDTGSQQATQAGETMQSVVGAAQRVTGIIAEIAAASDEQSQGIAQVSQAVSEME
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QVTQQNAALVQQSAASATSLEERACSLSQAVALFTLPESQASRPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC
>Mature Secondary Structure
MFKNVRVITGIIVLLAIFILLQGVSGRLFYMAIAQDRGNFSQSRALSYQQEQLADGWQTL
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
VMTRVTINRVAIRYLKQQNAGVAQLEIGSLLNAANASLDSAEGYFKNYRAAPRLPGQDAA
HHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCHH
LAAEVEHRFTALYRLLRDSSHYLRAGDYPAYGKLETQEAQEAMAKIYAQWRAQNHGLLQQ
HHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHH
GIDANQRSFGRMVWTLAGIALAVVLLIILAGVAARGILLRPLAQLHAHLRRLTAGDLSAT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LAGGRNELGSLAHSISEMQQALISIVGQVRNGADTLLHGSSDITVGNADLSSRTEQQAAA
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCCCEECCCCHHHHHHHHHHH
LEETAASMEQLTATVRQNADNARQASQLASSASATANQGGAVVGQVVTAMDEIADSSRKI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHH
ASITGVIDSIAFQTNILALNAAVESARAGEQGRGFAVVAGEVRSLAQRSAQAAREIRTLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
EDSVRRIDTGSQQATQAGETMQSVVGAAQRVTGIIAEIAAASDEQSQGIAQVSQAVSEME
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
QVTQQNAALVQQSAASATSLEERACSLSQAVALFTLPESQASRPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]