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The map label for this gene is resE [H]

Identifier: 238921580

GI number: 238921580

Start: 3619334

End: 3620800

Strand: Reverse

Name: resE [H]

Synonym: NT01EI_3733

Alternate gene names: 238921580

Gene position: 3620800-3619334 (Counterclockwise)

Preceding gene: 238921581

Following gene: 238921577

Centisome position: 94.98

GC content: 65.37

Gene sequence:

>1467_bases
ATGAGCCGCCTGAGCCTGGCGCAGCGCCTGACGCTGGTGTTTGCCCTGCTGCTGCTGGTGTGCAGCGCCCTGACCGGTTG
GCTGCAGCTGCGCAGTAATACGCAGTATAGCCAGCAGGTAATCCAGCGTCTGTCCGCGAATCTGGCGCGTCATATCGCCG
AGCATAACCCGCTGCTGCAGGCCGACGGCCTGAATCCGGCGTCGGTAAAAAACCTGTTCGATCAACTGATGGCGGTGAAC
CCCAGCGTGGAGGTTTATCTGCTGGATGAGCAGGGGCGGATCATTGGCGATGCGGCGCCGCCGGGGCGTATCGTGCGCCA
TCAGGTCAGTCTGGCGCCGATCGCGGCGTTCCTGGCGGGAAAATCGCTGCCGCTGTACGGTGACGATCCGCGCAGCCCGG
ACGCCCGTAAGGTGTTTAGCGCCGCGCCGCTATCGCTGAACGGCCATACGCGCGGCTATCTGTATGTGGTGCTGCTGGGA
GAGAACTACAGCCGGCTGAGCGACAACGTCCGGTTCGGCTCCGCCTGGCGCATGGCCAGCTGGTCGATAACCCTGATCCT
GGTCTGCGGGCTGTTGGCCTGGCTGCTGGTCTACCGCTGGGTCACCCGCCCGGTTCACGCCCTGACGCGTCAGGTGGGGC
GTCTGGAGCACGAAGGGCTGGAGACCGTACAGCCTGCGACGCTGGCCGCACTGCAGCAGATCCGCGGCGAGGATGAGGTC
GCCCAGCTGCAGCGGGCGTTTGGCCGCATGGCGCGGCGGATCACCAAGCAGTGGCAGCGCCTGGCCGAGCAGGATCGCCA
GCGGCGCGAGTTTATCACCACCGTCTCTCACGATCTGCGCACGCCCCTGACGTCGTTGCATGGCTATCTGGAGACGCTGA
GCCTGAAGCGGGATACCCTGAGCGCCGCCGATCGACGGCGTTACCTGGATACGGCGCTGGCCCAAAGCCAGAAGGTCGGG
CATCTGGCACAGCAGCTGTTTGAGCTGGCGCGCCTGGAGTACGGTGCGGTGAAGCCGCAGCGCGAGCCTTTCTCTTTTAG
CGAGCTGCTGCAGGATGTGTTTCAAAAGTTTGAGCTGGCGGCCGAGGCCCGCGGCCTGACGCTGAGCGCCGACGTAGCGA
CTGGCCTACCGCTGATTTCGGCTGATATCCATATGATGGAGCGGGTACTGACCAACCTGCTGGATAACGCCGTGCGCCAT
ACGCCGCAGGAGGGGCGCATCGTCGTACGCCTATGGCAGGAGGGGCGGCAGTTGTGGGTTGAGTTGTGCGACAGCGGTCC
CGGGATTCCCGATGGACTGCGCAGCGCGCTGTTCCAGCGGCCGCTGTCATCCAGCGGGGCGCGTTACGGCGCCGGGGGGC
TGGGGCTGCTGATCGTGAAACGGATGCTGGAGCTGCACGGCGGGGATATCGCTCTGATCGCGCGGCAGCGACAGGGTGCC
TGTTTTCGACTGTCGCTGCCGCTGTAG

Upstream 100 bases:

>100_bases
ACCGCCTGCGTACCAAGATCGAGGCCGATCCCGCCGAGCCGGCGCTGATCCTGACCGTCTGGGGCGCCGGCTACAGGTTC
GCCGACGCCGGGGGGGCGGT

Downstream 100 bases:

>100_bases
GGCTGTGGACTACAGTACGCCCTGCGCCAGCATGGCGTCGGCGACCTTCACGAAGCCCGCGATGTTGGCGCCGCGCACGT
AGTGCACCGGTCCGCTCTGA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 487

Protein sequence:

>488_residues
MSRLSLAQRLTLVFALLLLVCSALTGWLQLRSNTQYSQQVIQRLSANLARHIAEHNPLLQADGLNPASVKNLFDQLMAVN
PSVEVYLLDEQGRIIGDAAPPGRIVRHQVSLAPIAAFLAGKSLPLYGDDPRSPDARKVFSAAPLSLNGHTRGYLYVVLLG
ENYSRLSDNVRFGSAWRMASWSITLILVCGLLAWLLVYRWVTRPVHALTRQVGRLEHEGLETVQPATLAALQQIRGEDEV
AQLQRAFGRMARRITKQWQRLAEQDRQRREFITTVSHDLRTPLTSLHGYLETLSLKRDTLSAADRRRYLDTALAQSQKVG
HLAQQLFELARLEYGAVKPQREPFSFSELLQDVFQKFELAAEARGLTLSADVATGLPLISADIHMMERVLTNLLDNAVRH
TPQEGRIVVRLWQEGRQLWVELCDSGPGIPDGLRSALFQRPLSSSGARYGAGGLGLLIVKRMLELHGGDIALIARQRQGA
CFRLSLPL

Sequences:

>Translated_488_residues
MSRLSLAQRLTLVFALLLLVCSALTGWLQLRSNTQYSQQVIQRLSANLARHIAEHNPLLQADGLNPASVKNLFDQLMAVN
PSVEVYLLDEQGRIIGDAAPPGRIVRHQVSLAPIAAFLAGKSLPLYGDDPRSPDARKVFSAAPLSLNGHTRGYLYVVLLG
ENYSRLSDNVRFGSAWRMASWSITLILVCGLLAWLLVYRWVTRPVHALTRQVGRLEHEGLETVQPATLAALQQIRGEDEV
AQLQRAFGRMARRITKQWQRLAEQDRQRREFITTVSHDLRTPLTSLHGYLETLSLKRDTLSAADRRRYLDTALAQSQKVG
HLAQQLFELARLEYGAVKPQREPFSFSELLQDVFQKFELAAEARGLTLSADVATGLPLISADIHMMERVLTNLLDNAVRH
TPQEGRIVVRLWQEGRQLWVELCDSGPGIPDGLRSALFQRPLSSSGARYGAGGLGLLIVKRMLELHGGDIALIARQRQGA
CFRLSLPL
>Mature_487_residues
SRLSLAQRLTLVFALLLLVCSALTGWLQLRSNTQYSQQVIQRLSANLARHIAEHNPLLQADGLNPASVKNLFDQLMAVNP
SVEVYLLDEQGRIIGDAAPPGRIVRHQVSLAPIAAFLAGKSLPLYGDDPRSPDARKVFSAAPLSLNGHTRGYLYVVLLGE
NYSRLSDNVRFGSAWRMASWSITLILVCGLLAWLLVYRWVTRPVHALTRQVGRLEHEGLETVQPATLAALQQIRGEDEVA
QLQRAFGRMARRITKQWQRLAEQDRQRREFITTVSHDLRTPLTSLHGYLETLSLKRDTLSAADRRRYLDTALAQSQKVGH
LAQQLFELARLEYGAVKPQREPFSFSELLQDVFQKFELAAEARGLTLSADVATGLPLISADIHMMERVLTNLLDNAVRHT
PQEGRIVVRLWQEGRQLWVELCDSGPGIPDGLRSALFQRPLSSSGARYGAGGLGLLIVKRMLELHGGDIALIARQRQGAC
FRLSLPL

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=279, Percent_Identity=30.4659498207885, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87081816, Length=334, Percent_Identity=28.4431137724551, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI48994928, Length=247, Percent_Identity=29.9595141700405, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=31.858407079646, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=28.3261802575107, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788393, Length=258, Percent_Identity=28.6821705426357, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788279, Length=307, Percent_Identity=25.0814332247557, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788549, Length=239, Percent_Identity=28.4518828451883, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI87082128, Length=310, Percent_Identity=24.5161290322581, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788713, Length=230, Percent_Identity=27.8260869565217, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790861, Length=416, Percent_Identity=25.4807692307692, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1786783, Length=314, Percent_Identity=26.7515923566879, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1787374, Length=308, Percent_Identity=25.974025974026, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI145693157, Length=234, Percent_Identity=28.2051282051282, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=24.6913580246914, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=313, Percent_Identity=28.1150159744409, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790551, Length=285, Percent_Identity=26.3157894736842, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787894, Length=265, Percent_Identity=30.188679245283, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54440; Mature: 54308

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLSLAQRLTLVFALLLLVCSALTGWLQLRSNTQYSQQVIQRLSANLARHIAEHNPLLQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
ADGLNPASVKNLFDQLMAVNPSVEVYLLDEQGRIIGDAAPPGRIVRHQVSLAPIAAFLAG
ECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHCC
KSLPLYGDDPRSPDARKVFSAAPLSLNGHTRGYLYVVLLGENYSRLSDNVRFGSAWRMAS
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHCCCCCCCCHHHHH
WSITLILVCGLLAWLLVYRWVTRPVHALTRQVGRLEHEGLETVQPATLAALQQIRGEDEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHCCCHHH
AQLQRAFGRMARRITKQWQRLAEQDRQRREFITTVSHDLRTPLTSLHGYLETLSLKRDTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAADRRRYLDTALAQSQKVGHLAQQLFELARLEYGAVKPQREPFSFSELLQDVFQKFELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
AEARGLTLSADVATGLPLISADIHMMERVLTNLLDNAVRHTPQEGRIVVRLWQEGRQLWV
HHHCCCEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHH
ELCDSGPGIPDGLRSALFQRPLSSSGARYGAGGLGLLIVKRMLELHGGDIALIARQRQGA
HHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCC
CFRLSLPL
EEEEECCC
>Mature Secondary Structure 
SRLSLAQRLTLVFALLLLVCSALTGWLQLRSNTQYSQQVIQRLSANLARHIAEHNPLLQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCEE
ADGLNPASVKNLFDQLMAVNPSVEVYLLDEQGRIIGDAAPPGRIVRHQVSLAPIAAFLAG
ECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHHHHCC
KSLPLYGDDPRSPDARKVFSAAPLSLNGHTRGYLYVVLLGENYSRLSDNVRFGSAWRMAS
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEEEEECCCHHHHHCCCCCCCCHHHHH
WSITLILVCGLLAWLLVYRWVTRPVHALTRQVGRLEHEGLETVQPATLAALQQIRGEDEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHCCCHHH
AQLQRAFGRMARRITKQWQRLAEQDRQRREFITTVSHDLRTPLTSLHGYLETLSLKRDTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAADRRRYLDTALAQSQKVGHLAQQLFELARLEYGAVKPQREPFSFSELLQDVFQKFELA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHH
AEARGLTLSADVATGLPLISADIHMMERVLTNLLDNAVRHTPQEGRIVVRLWQEGRQLWV
HHHCCCEEECHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHH
ELCDSGPGIPDGLRSALFQRPLSSSGARYGAGGLGLLIVKRMLELHGGDIALIARQRQGA
HHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCC
CFRLSLPL
EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]