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The map label for this gene is speB

Identifier: 238921230

GI number: 238921230

Start: 3260629

End: 3261543

Strand: Reverse

Name: speB

Synonym: NT01EI_3373

Alternate gene names: 238921230

Gene position: 3261543-3260629 (Counterclockwise)

Preceding gene: 238921231

Following gene: 238921227

Centisome position: 85.55

GC content: 61.64

Gene sequence:

>915_bases
ATGTGTACTCTGGGGCATAAGCCTGATAACTCTCTGGTATCCAACGCCTTTGGTTTCCTGCGTCTGCCGCTGGACTTCAT
GCCGTATGACGGCGACGCCGACTGGGTGATCACCGGAGTGCCGTTCGATATGGCGACCTCCGGCCGCGCCGGTGGCCGAC
ACGGGCCGGCGGCTATCCGTCAGGTTTCCACCAACCTGGCCTGGGAAGGCAAGCGCTGGCCGTGGAACTTCGATATGCGC
GACCGCCTGAAGGTGGTGGACTGCGGCGACGTGGTCTTCAGTTTCGGCGACGCCCAGGAGATGAGCGATAACCTGCAGGC
TCACGCCGAGCGTCTGTTGGCCAGCGGGAAACGCTGCCTGACCTTTGGCGGTGACCATTTTATCACCCTGCCGCTGCTGC
GCGCTCACGCCAAGCACTTCGGCAAAATGGCGCTGGTGCACTTCGACGCCCACACCGATACCTATGCGCACGGCAGCAAG
TTCGATCACGGCACCATGTTCTTCCATGCGCCGAACGAGGGGCTGATCGATCCGCAGCATTCGGTGCAGATCGGTATTCG
CACCGAGTACGATCATGACAACGGTTTTACCGTGCTGGATGCCGCCCAGGTGAACGATCGCAGCGTAGAGGATGTGCTGG
CCGAGGTTAAGCGTATCGTCGGTGATCTGCCGGTTTATCTGACTTTTGACATCGACTGCCTGGATCCGGCCCATGCCCCG
GGCACCGGCACACCGGTGATCGGCGGCCTGACCTCCGATCGCGCCCTGAAGCTGGTGCGTGGCCTGCAGGATCTGGATAT
TGTCGGCATGGACGTTGTCGAAGTCGCGCCGGCCTATGATCAGTCAGAGATCACCGCCCTGGCGGCGGCGACGCTGGCGC
TGGAGATGCTGTATATCCAGGCGGCGAAGAAGTAA

Upstream 100 bases:

>100_bases
CTCGTCGGGTTAACGACGCGGGAGGGATTTTTTTTTCATCGCGACTCCGTCAGCCTGGCCGACATGCGGCGCGGCGACGG
GATTTATAGGAGGAGTGAGT

Downstream 100 bases:

>100_bases
CGTCCGCTGAACGGGTAAGGCCGGGCAGACGCCCGGCCTTTTTCATGCATCGCGATCACACCCGCCGCCATACGAGGCGC
GGGCCTGCCGGTAGAGCGCC

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase; AUH

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MCTLGHKPDNSLVSNAFGFLRLPLDFMPYDGDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEGKRWPWNFDMR
DRLKVVDCGDVVFSFGDAQEMSDNLQAHAERLLASGKRCLTFGGDHFITLPLLRAHAKHFGKMALVHFDAHTDTYAHGSK
FDHGTMFFHAPNEGLIDPQHSVQIGIRTEYDHDNGFTVLDAAQVNDRSVEDVLAEVKRIVGDLPVYLTFDIDCLDPAHAP
GTGTPVIGGLTSDRALKLVRGLQDLDIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKK

Sequences:

>Translated_304_residues
MCTLGHKPDNSLVSNAFGFLRLPLDFMPYDGDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEGKRWPWNFDMR
DRLKVVDCGDVVFSFGDAQEMSDNLQAHAERLLASGKRCLTFGGDHFITLPLLRAHAKHFGKMALVHFDAHTDTYAHGSK
FDHGTMFFHAPNEGLIDPQHSVQIGIRTEYDHDNGFTVLDAAQVNDRSVEDVLAEVKRIVGDLPVYLTFDIDCLDPAHAP
GTGTPVIGGLTSDRALKLVRGLQDLDIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKK
>Mature_304_residues
MCTLGHKPDNSLVSNAFGFLRLPLDFMPYDGDADWVITGVPFDMATSGRAGGRHGPAAIRQVSTNLAWEGKRWPWNFDMR
DRLKVVDCGDVVFSFGDAQEMSDNLQAHAERLLASGKRCLTFGGDHFITLPLLRAHAKHFGKMALVHFDAHTDTYAHGSK
FDHGTMFFHAPNEGLIDPQHSVQIGIRTEYDHDNGFTVLDAAQVNDRSVEDVLAEVKRIVGDLPVYLTFDIDCLDPAHAP
GTGTPVIGGLTSDRALKLVRGLQDLDIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQAAKK

Specific function: Catalyzes the formation of putrescine from agmatine

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily

Homologues:

Organism=Homo sapiens, GI37537722, Length=306, Percent_Identity=42.156862745098, Blast_Score=212, Evalue=4e-55,
Organism=Escherichia coli, GI1789306, Length=304, Percent_Identity=86.1842105263158, Blast_Score=531, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI71996843, Length=295, Percent_Identity=22.3728813559322, Blast_Score=64, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPEB_EDWI9 (C5BAV1)

Other databases:

- EMBL:   CP001600
- RefSeq:   YP_002934745.1
- ProteinModelPortal:   C5BAV1
- GeneID:   7959672
- GenomeReviews:   CP001600_GR
- KEGG:   eic:NT01EI_3373
- OMA:   TNLAWEG
- ProtClustDB:   PRK02190
- HAMAP:   MF_01418
- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855
- Gene3D:   G3DSA:3.40.800.10
- PANTHER:   PTHR11358
- TIGRFAMs:   TIGR01230

Pfam domain/function: PF00491 Arginase

EC number: =3.5.3.11

Molecular weight: Translated: 33259; Mature: 33259

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS01053 ARGINASE_1; PS51409 ARGINASE_2; PS00147 ARGINASE_1 ; PS00148 ARGINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCTLGHKPDNSLVSNAFGFLRLPLDFMPYDGDADWVITGVPFDMATSGRAGGRHGPAAIR
CCCCCCCCCHHHHHHCCCEEECCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
QVSTNLAWEGKRWPWNFDMRDRLKVVDCGDVVFSFGDAQEMSDNLQAHAERLLASGKRCL
HHHHCCCCCCCCCCCCCCHHHCEEEEECCHHEEECCCHHHHHHHHHHHHHHHHHCCCEEE
TFGGDHFITLPLLRAHAKHFGKMALVHFDAHTDTYAHGSKFDHGTMFFHAPNEGLIDPQH
EECCCCEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
SVQIGIRTEYDHDNGFTVLDAAQVNDRSVEDVLAEVKRIVGDLPVYLTFDIDCLDPAHAP
CEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCC
GTGTPVIGGLTSDRALKLVRGLQDLDIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQ
CCCCCEECCCCCHHHHHHHHCCCCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AAKK
HCCC
>Mature Secondary Structure
MCTLGHKPDNSLVSNAFGFLRLPLDFMPYDGDADWVITGVPFDMATSGRAGGRHGPAAIR
CCCCCCCCCHHHHHHCCCEEECCCEECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHH
QVSTNLAWEGKRWPWNFDMRDRLKVVDCGDVVFSFGDAQEMSDNLQAHAERLLASGKRCL
HHHHCCCCCCCCCCCCCCHHHCEEEEECCHHEEECCCHHHHHHHHHHHHHHHHHCCCEEE
TFGGDHFITLPLLRAHAKHFGKMALVHFDAHTDTYAHGSKFDHGTMFFHAPNEGLIDPQH
EECCCCEEEHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
SVQIGIRTEYDHDNGFTVLDAAQVNDRSVEDVLAEVKRIVGDLPVYLTFDIDCLDPAHAP
CEEEEEEEECCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCC
GTGTPVIGGLTSDRALKLVRGLQDLDIVGMDVVEVAPAYDQSEITALAAATLALEMLYIQ
CCCCCEECCCCCHHHHHHHHCCCCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
AAKK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA