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The map label for this gene is pagC [H]

Identifier: 238921187

GI number: 238921187

Start: 3215973

End: 3216620

Strand: Reverse

Name: pagC [H]

Synonym: NT01EI_3328

Alternate gene names: 238921187

Gene position: 3216620-3215973 (Counterclockwise)

Preceding gene: 238921188

Following gene: 238921186

Centisome position: 84.37

GC content: 46.45

Gene sequence:

>648_bases
GTGCCGACGTTATCGAATGCTAATAGAAAAAGTGTATTTCCCTCATTTATTGAAAAAGGAAAAAAGATGAAAAAAATACT
GATAAGTCTGGCTCTGGTGAGCGGTGTAATGGCGAGCCCTGCCGCTTTAGCCGCCGAGCAAACGGCCAGCATAGGATATG
CCCATGCACAGCTTCAGGATGTTGGCAACCTTAATGGTTTCACGCTTCAGTACCGCTATGAGTGGGATACCCTCTGGAGT
GTGATTGGCGGCTTGAGCTATATGCAGGGAAGTAACAATAATGCCTATCAAGATGCTTGGGGAGATACATATAAAACTGA
TATTAATGCCAAATACACCTCCCTGCTGCTGGGGCCGGCATACCGTATAAATGATTATGTCAGCGTTTACGGTCTGTTGG
GTGCGGCTTATACCAAAATGGACGGTAGCTATGAATGGCGTAACAGTGTCGGTGCCGATACACCGAATGGTCATCTCAGT
ATCACCTCATCCAGCCAGGCGGTAAAACTGGCCTACGCCGCCGGTGTTGTTATTAATCCCATCAATACTCTTTCCATAAA
TATAGGTTATGAAGGCTCCCAGGCTGATCTGTATGGGGGGAATAAAACCATTAATGGATTCACGGTGGGGATAGGTTGGC
GTTTCTAA

Upstream 100 bases:

>100_bases
TGGCACCGGGGGGCTGAGCGCGGAAAGCGGGTGAAATGTTTTTGGGGCGATCGGGTTTCACAGGATGCGCTGCGTACCTG
GCGGCACAATTATCCACTCT

Downstream 100 bases:

>100_bases
TTTTGCCAATCACATCCCCGGCGCTGTCAATACCGTTTTTCCTGTTGGCCTGAAGTATAAGGATGAGTGTGCGTCGCAAT
GAATAAACATTTATATCGCA

Product: resistance to complement killing

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MPTLSNANRKSVFPSFIEKGKKMKKILISLALVSGVMASPAALAAEQTASIGYAHAQLQDVGNLNGFTLQYRYEWDTLWS
VIGGLSYMQGSNNNAYQDAWGDTYKTDINAKYTSLLLGPAYRINDYVSVYGLLGAAYTKMDGSYEWRNSVGADTPNGHLS
ITSSSQAVKLAYAAGVVINPINTLSINIGYEGSQADLYGGNKTINGFTVGIGWRF

Sequences:

>Translated_215_residues
MPTLSNANRKSVFPSFIEKGKKMKKILISLALVSGVMASPAALAAEQTASIGYAHAQLQDVGNLNGFTLQYRYEWDTLWS
VIGGLSYMQGSNNNAYQDAWGDTYKTDINAKYTSLLLGPAYRINDYVSVYGLLGAAYTKMDGSYEWRNSVGADTPNGHLS
ITSSSQAVKLAYAAGVVINPINTLSINIGYEGSQADLYGGNKTINGFTVGIGWRF
>Mature_214_residues
PTLSNANRKSVFPSFIEKGKKMKKILISLALVSGVMASPAALAAEQTASIGYAHAQLQDVGNLNGFTLQYRYEWDTLWSV
IGGLSYMQGSNNNAYQDAWGDTYKTDINAKYTSLLLGPAYRINDYVSVYGLLGAAYTKMDGSYEWRNSVGADTPNGHLSI
TSSSQAVKLAYAAGVVINPINTLSINIGYEGSQADLYGGNKTINGFTVGIGWRF

Specific function: Essential for full virulence and survival within macrophages [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ail/ompX/pagC/lom family [H]

Homologues:

Organism=Escherichia coli, GI1787034, Length=197, Percent_Identity=29.4416243654822, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000758
- InterPro:   IPR011250 [H]

Pfam domain/function: PF06316 Ail_Lom [H]

EC number: NA

Molecular weight: Translated: 23224; Mature: 23093

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLSNANRKSVFPSFIEKGKKMKKILISLALVSGVMASPAALAAEQTASIGYAHAQLQD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHH
VGNLNGFTLQYRYEWDTLWSVIGGLSYMQGSNNNAYQDAWGDTYKTDINAKYTSLLLGPA
CCCCCCEEEEEEECHHHHHHHHCCHHEECCCCCCCCCCCCCCCEECCCCCCEEEEEECCC
YRINDYVSVYGLLGAAYTKMDGSYEWRNSVGADTPNGHLSITSSSQAVKLAYAAGVVINP
HHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEEECCCCEEEEEEECCEEECC
INTLSINIGYEGSQADLYGGNKTINGFTVGIGWRF
CEEEEEEECCCCCCCEECCCCEEECEEEEEEEECC
>Mature Secondary Structure 
PTLSNANRKSVFPSFIEKGKKMKKILISLALVSGVMASPAALAAEQTASIGYAHAQLQD
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHH
VGNLNGFTLQYRYEWDTLWSVIGGLSYMQGSNNNAYQDAWGDTYKTDINAKYTSLLLGPA
CCCCCCEEEEEEECHHHHHHHHCCHHEECCCCCCCCCCCCCCCEECCCCCCEEEEEECCC
YRINDYVSVYGLLGAAYTKMDGSYEWRNSVGADTPNGHLSITSSSQAVKLAYAAGVVINP
HHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCEEEEECCCCEEEEEEECCEEECC
INTLSINIGYEGSQADLYGGNKTINGFTVGIGWRF
CEEEEEEECCCCCCCEECCCCEEECEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1846140; 11677609 [H]