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The map label for this gene is hpmA [H]

Identifier: 238921186

GI number: 238921186

Start: 3213543

End: 3215894

Strand: Reverse

Name: hpmA [H]

Synonym: NT01EI_3327

Alternate gene names: 238921186

Gene position: 3215894-3213543 (Counterclockwise)

Preceding gene: 238921187

Following gene: 238921185

Centisome position: 84.36

GC content: 56.97

Gene sequence:

>2352_bases
ATGAATAAACATTTATATCGCATTATTTTTAGCAAAGCGCGCGGCATGTTAATGGTAGTCGCGGAGATTACCCGCTCTCA
TCGGGCGGGTCCGGCGCACTCATCCAGGGTGATAAGGCATAACGATGTACGGCTGGCCGCCCGCCTTTCACCGTTAACCT
GGGGGGTATTCCTCGCCTTGGCCTGGGTCAATCCCGCCAGCGCCGGGATTGTTGCCGATGCCAGTGCGCCAGGCCGCCAA
CAGCCACACATTGTCAGCAGCGCCAACGGTACGCCCCAGGTAAATATCCAGTCACCGAGTGCCGGTGGGGTATCCAACAA
TCTCTACAGCCAGTTTGATGTGGATAAGCGCGGGGTCATTCTCAACAACAGCCATCAGAATACCCCGACCCATATCGCTG
GCATGGTGGCCGCAAATCCCAATTTGGCACGGGGTGAGGCGACGGTGATCCTCAACCAGGTTAACTCCCGAAACCTGAGT
CAACTGAATGGCTATATCGAGGTCGCCGGGCAAAAGGCGCAGATCGTTATTGCTAACCCCGCCGGGATCAGCTGTGATGG
CTGCGGCTTTATTAATGCCAATCGCGCTACGCTGACCACAGGAACACCACAGCTTCACCGTGGTACTCTGACCGGTTACC
GCGTGAATGGCGGAAATATCACCATTACAGGCCAGGGACTCGACAGCCGCGAGCAGGACTATACCCACATCATCGCCCGT
AGTGTGCAGGTGAATGCGGAGGTCCGGGCTAAAAGTCTGAGTATCACCACCGGGCGTAACCAGGTGGATACGGTACATCA
AACCATCACGGCACTGGCCGATGAGGGGAGCGAAAAACCCGTAATGGCCCTGGATGTCTCTGCACTGGGGGGAATGTATG
CGGGGAAAATCCGCCTGATGGGGACCGAGACGGGAGTGGGTGTCCATAACGCTGGCGATATTGGGGCAACGGCAGGCAAT
GTAGTTTTAACTGCAGACGGCCGCATTGAAAACAGCGGAAAAATCAGCAGCACCGGTGATACCGAATTGGCCAGTCAGCG
TGATATCCAGAACCGTGGGCGTATTTACAGTCAGCAGCGGCTCACGCTGGATAGCCATGGCACCATGAGCAACCAAGGCT
CTCTGGTGAGCGGGCGTACGCTGAGCGCCAACGCAGAAACATTCTCCGCTGCAGCCGGGAGCGTACTGGCCGCAGGCGTA
GACCGTCAGGGTAAGCTGACACAGTCCGGCGATATCCTCCTTACTACACGCGGTCAGCTGAGTGCGCATGGGAAGAATCT
TGCCAGTCGGCATATCCAGGCCAAAGGCCAGGGTATCGATTTCAGCGCCAGCCAGACCGCAGCCCAATCGATATCCCTGG
ATGCACAGCGCGGAGCGCTGTCTACCCGCCATGCCATCCTGGATGCAGCGCAAACCCTATCGGCTCACACCTCCTCCCAT
TTCAACAACGAAGGTGGTGCGTTGAGCGCCAAAACGCTCCAGATCTCTGCTCGTGAGGTCAATAACCGTATGGGCATCCT
CACCCAGTTGGGTACGGACGATTTCGAACTCTCCCCCGTAGGCACGCTGGATAATCAGGGGGGACATATCCGGAGTAACG
GTCAGGGCCTGCGCGTAAACACCGCCTCATTGGATAACCGCAGCGGAGAAATCACCCATGCCGGAACCGGCGAACTGCGC
CTCTCGGCGCTTCAGACCATCGAGAATGAGGGGGGCGTAATCCAAAGCGCCGGGCATATTACCACCCACACCACAGCGCT
CAACAATACTCACGGACAGTTAATTGCCTCACGCGCACTCCAGCTGACTGCAACAGCGCTCAATAACCAGGACGGCCTGA
CAAGCAGCGGGGAGGAGAGCGTTCTTCAACTGGCTGACTCGCTAAATAATCGCCAGGGGCGGGTAATCAGTACGGGCGAT
TTACACCTTACGACGACCGAACTGGATAACCGGCAAGGTGTACTCGCTACGCGCCAATCCCTCAAGCTGCAGACCTCCAG
CCTGGATAATCAGGCCGGTGCTATCAAGGCCGGAAAAAATGCGCAGCTGGCTATCACTCAGCAGCTTGATAATCGCCAGA
GGGGCATCATCGGTGCCACCGGTGATCTCACCCTACAGGCCGATCGTATCCTGAATCAGCAGGGTAAACTGATCACTAAC
GGCCATGGGCGGCTTACCGCTACCGATATCGATAACCGTCATGGGCAGATAGCTGGCGGCTCTTCTCTGCGGCTGCACAC
TCTTCGACTGAATAACAGCGATGACGGGCAGATACAAAGTGGCGGTGATATGGCGCTCCATGCCTCTTATCTCCTCAACC
GGGAAACAGTCGATAACGGGGGGGATCAGTAG

Upstream 100 bases:

>100_bases
GGGGATAGGTTGGCGTTTCTAATTTTGCCAATCACATCCCCGGCGCTGTCAATACCGTTTTTCCTGTTGGCCTGAAGTAT
AAGGATGAGTGTGCGTCGCA

Downstream 100 bases:

>100_bases
CAAGGGGCTGTTGGTGCTGGAGACCCCGTTGCTGGATAACCACCGCGGTCTGCTGCTGGCGGGAAAAAGCCTGACGCTGC
TCAATACGCTGCTGGATAAC

Product: filamentous hemagglutinin family outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 783; Mature: 783

Protein sequence:

>783_residues
MNKHLYRIIFSKARGMLMVVAEITRSHRAGPAHSSRVIRHNDVRLAARLSPLTWGVFLALAWVNPASAGIVADASAPGRQ
QPHIVSSANGTPQVNIQSPSAGGVSNNLYSQFDVDKRGVILNNSHQNTPTHIAGMVAANPNLARGEATVILNQVNSRNLS
QLNGYIEVAGQKAQIVIANPAGISCDGCGFINANRATLTTGTPQLHRGTLTGYRVNGGNITITGQGLDSREQDYTHIIAR
SVQVNAEVRAKSLSITTGRNQVDTVHQTITALADEGSEKPVMALDVSALGGMYAGKIRLMGTETGVGVHNAGDIGATAGN
VVLTADGRIENSGKISSTGDTELASQRDIQNRGRIYSQQRLTLDSHGTMSNQGSLVSGRTLSANAETFSAAAGSVLAAGV
DRQGKLTQSGDILLTTRGQLSAHGKNLASRHIQAKGQGIDFSASQTAAQSISLDAQRGALSTRHAILDAAQTLSAHTSSH
FNNEGGALSAKTLQISAREVNNRMGILTQLGTDDFELSPVGTLDNQGGHIRSNGQGLRVNTASLDNRSGEITHAGTGELR
LSALQTIENEGGVIQSAGHITTHTTALNNTHGQLIASRALQLTATALNNQDGLTSSGEESVLQLADSLNNRQGRVISTGD
LHLTTTELDNRQGVLATRQSLKLQTSSLDNQAGAIKAGKNAQLAITQQLDNRQRGIIGATGDLTLQADRILNQQGKLITN
GHGRLTATDIDNRHGQIAGGSSLRLHTLRLNNSDDGQIQSGGDMALHASYLLNRETVDNGGDQ

Sequences:

>Translated_783_residues
MNKHLYRIIFSKARGMLMVVAEITRSHRAGPAHSSRVIRHNDVRLAARLSPLTWGVFLALAWVNPASAGIVADASAPGRQ
QPHIVSSANGTPQVNIQSPSAGGVSNNLYSQFDVDKRGVILNNSHQNTPTHIAGMVAANPNLARGEATVILNQVNSRNLS
QLNGYIEVAGQKAQIVIANPAGISCDGCGFINANRATLTTGTPQLHRGTLTGYRVNGGNITITGQGLDSREQDYTHIIAR
SVQVNAEVRAKSLSITTGRNQVDTVHQTITALADEGSEKPVMALDVSALGGMYAGKIRLMGTETGVGVHNAGDIGATAGN
VVLTADGRIENSGKISSTGDTELASQRDIQNRGRIYSQQRLTLDSHGTMSNQGSLVSGRTLSANAETFSAAAGSVLAAGV
DRQGKLTQSGDILLTTRGQLSAHGKNLASRHIQAKGQGIDFSASQTAAQSISLDAQRGALSTRHAILDAAQTLSAHTSSH
FNNEGGALSAKTLQISAREVNNRMGILTQLGTDDFELSPVGTLDNQGGHIRSNGQGLRVNTASLDNRSGEITHAGTGELR
LSALQTIENEGGVIQSAGHITTHTTALNNTHGQLIASRALQLTATALNNQDGLTSSGEESVLQLADSLNNRQGRVISTGD
LHLTTTELDNRQGVLATRQSLKLQTSSLDNQAGAIKAGKNAQLAITQQLDNRQRGIIGATGDLTLQADRILNQQGKLITN
GHGRLTATDIDNRHGQIAGGSSLRLHTLRLNNSDDGQIQSGGDMALHASYLLNRETVDNGGDQ
>Mature_783_residues
MNKHLYRIIFSKARGMLMVVAEITRSHRAGPAHSSRVIRHNDVRLAARLSPLTWGVFLALAWVNPASAGIVADASAPGRQ
QPHIVSSANGTPQVNIQSPSAGGVSNNLYSQFDVDKRGVILNNSHQNTPTHIAGMVAANPNLARGEATVILNQVNSRNLS
QLNGYIEVAGQKAQIVIANPAGISCDGCGFINANRATLTTGTPQLHRGTLTGYRVNGGNITITGQGLDSREQDYTHIIAR
SVQVNAEVRAKSLSITTGRNQVDTVHQTITALADEGSEKPVMALDVSALGGMYAGKIRLMGTETGVGVHNAGDIGATAGN
VVLTADGRIENSGKISSTGDTELASQRDIQNRGRIYSQQRLTLDSHGTMSNQGSLVSGRTLSANAETFSAAAGSVLAAGV
DRQGKLTQSGDILLTTRGQLSAHGKNLASRHIQAKGQGIDFSASQTAAQSISLDAQRGALSTRHAILDAAQTLSAHTSSH
FNNEGGALSAKTLQISAREVNNRMGILTQLGTDDFELSPVGTLDNQGGHIRSNGQGLRVNTASLDNRSGEITHAGTGELR
LSALQTIENEGGVIQSAGHITTHTTALNNTHGQLIASRALQLTATALNNQDGLTSSGEESVLQLADSLNNRQGRVISTGD
LHLTTTELDNRQGVLATRQSLKLQTSSLDNQAGAIKAGKNAQLAITQQLDNRQRGIIGATGDLTLQADRILNQQGKLITN
GHGRLTATDIDNRHGQIAGGSSLRLHTLRLNNSDDGQIQSGGDMALHASYLLNRETVDNGGDQ

Specific function: Cell-bound hemolysin, which releases heme-iron from erythrocytes by interaction with the erythrocyte membrane. HpmA requires hpmB function [H]

COG id: COG3210

COG function: function code U; Large exoproteins involved in heme utilization or adhesion

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008638
- InterPro:   IPR012334
- InterPro:   IPR011050
- InterPro:   IPR011102 [H]

Pfam domain/function: PF05860 Haemagg_act [H]

EC number: NA

Molecular weight: Translated: 82234; Mature: 82234

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKHLYRIIFSKARGMLMVVAEITRSHRAGPAHSSRVIRHNDVRLAARLSPLTWGVFLAL
CCCCEEEHHHHHCCCEEEEEEHHHHHCCCCCCCCCCEEEECCEEEEEECCCHHHHHHHHH
AWVNPASAGIVADASAPGRQQPHIVSSANGTPQVNIQSPSAGGVSNNLYSQFDVDKRGVI
EECCCCCCCEEEECCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCHHCCCCCCCEE
LNNSHQNTPTHIAGMVAANPNLARGEATVILNQVNSRNLSQLNGYIEVAGQKAQIVIANP
EECCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHCCEEEECCCEEEEEEECC
AGISCDGCGFINANRATLTTGTPQLHRGTLTGYRVNGGNITITGQGLDSREQDYTHIIAR
CCCCCCCCCEEECCCEEEECCCCCCCCCCEEEEEEECCEEEEEECCCCCCCHHHHHHHHH
SVQVNAEVRAKSLSITTGRNQVDTVHQTITALADEGSEKPVMALDVSALGGMYAGKIRLM
EEEECCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCEEECEEEEE
GTETGVGVHNAGDIGATAGNVVLTADGRIENSGKISSTGDTELASQRDIQNRGRIYSQQR
ECCCCCCCCCCCCCCCCCCCEEEEECCEECCCCCCCCCCCCHHHHHHCHHHHCCEEECEE
LTLDSHGTMSNQGSLVSGRTLSANAETFSAAAGSVLAAGVDRQGKLTQSGDILLTTRGQL
EEECCCCCCCCCCCEEECCEEECCCCHHHHHCCCEEEECCCCCCCEECCCCEEEEECCCC
SAHGKNLASRHIQAKGQGIDFSASQTAAQSISLDAQRGALSTRHAILDAAQTLSAHTSSH
CCCCCHHHHHHHCCCCCCCCCCCCHHHHHHEECCHHCCCCHHHHHHHHHHHHHHHHHHHC
FNNEGGALSAKTLQISAREVNNRMGILTQLGTDDFELSPVGTLDNQGGHIRSNGQGLRVN
CCCCCCEEEEEEEEEEHHHHCCCCEEEEECCCCCEECCCCCCCCCCCCEEECCCCEEEEE
TASLDNRSGEITHAGTGELRLSALQTIENEGGVIQSAGHITTHTTALNNTHGQLIASRAL
ECCCCCCCCEEEECCCCCEEHHHHHHHHCCCCEEEECCCEEEEEEEECCCCHHHHHHHHH
QLTATALNNQDGLTSSGEESVLQLADSLNNRQGRVISTGDLHLTTTELDNRQGVLATRQS
EEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCEEEEEECCCCCCCEEEEHHH
LKLQTSSLDNQAGAIKAGKNAQLAITQQLDNRQRGIIGATGDLTLQADRILNQQGKLITN
HEEEECCCCCCCCCEECCCCCEEEEEECCCCCCCCEEECCCCEEEEHHHHHCCCCCEEEC
GHGRLTATDIDNRHGQIAGGSSLRLHTLRLNNSDDGQIQSGGDMALHASYLLNRETVDNG
CCCEEEEEECCCCCCEEECCCCEEEEEEEECCCCCCCEECCCCEEEEEEHHCCCCCCCCC
GDQ
CCC
>Mature Secondary Structure
MNKHLYRIIFSKARGMLMVVAEITRSHRAGPAHSSRVIRHNDVRLAARLSPLTWGVFLAL
CCCCEEEHHHHHCCCEEEEEEHHHHHCCCCCCCCCCEEEECCEEEEEECCCHHHHHHHHH
AWVNPASAGIVADASAPGRQQPHIVSSANGTPQVNIQSPSAGGVSNNLYSQFDVDKRGVI
EECCCCCCCEEEECCCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCHHCCCCCCCEE
LNNSHQNTPTHIAGMVAANPNLARGEATVILNQVNSRNLSQLNGYIEVAGQKAQIVIANP
EECCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCCCHHHHCCEEEECCCEEEEEEECC
AGISCDGCGFINANRATLTTGTPQLHRGTLTGYRVNGGNITITGQGLDSREQDYTHIIAR
CCCCCCCCCEEECCCEEEECCCCCCCCCCEEEEEEECCEEEEEECCCCCCCHHHHHHHHH
SVQVNAEVRAKSLSITTGRNQVDTVHQTITALADEGSEKPVMALDVSALGGMYAGKIRLM
EEEECCEEEEEEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEHHHHCCEEECEEEEE
GTETGVGVHNAGDIGATAGNVVLTADGRIENSGKISSTGDTELASQRDIQNRGRIYSQQR
ECCCCCCCCCCCCCCCCCCCEEEEECCEECCCCCCCCCCCCHHHHHHCHHHHCCEEECEE
LTLDSHGTMSNQGSLVSGRTLSANAETFSAAAGSVLAAGVDRQGKLTQSGDILLTTRGQL
EEECCCCCCCCCCCEEECCEEECCCCHHHHHCCCEEEECCCCCCCEECCCCEEEEECCCC
SAHGKNLASRHIQAKGQGIDFSASQTAAQSISLDAQRGALSTRHAILDAAQTLSAHTSSH
CCCCCHHHHHHHCCCCCCCCCCCCHHHHHHEECCHHCCCCHHHHHHHHHHHHHHHHHHHC
FNNEGGALSAKTLQISAREVNNRMGILTQLGTDDFELSPVGTLDNQGGHIRSNGQGLRVN
CCCCCCEEEEEEEEEEHHHHCCCCEEEEECCCCCEECCCCCCCCCCCCEEECCCCEEEEE
TASLDNRSGEITHAGTGELRLSALQTIENEGGVIQSAGHITTHTTALNNTHGQLIASRAL
ECCCCCCCCEEEECCCCCEEHHHHHHHHCCCCEEEECCCEEEEEEEECCCCHHHHHHHHH
QLTATALNNQDGLTSSGEESVLQLADSLNNRQGRVISTGDLHLTTTELDNRQGVLATRQS
EEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCEEEEEECCCCCCCEEEEHHH
LKLQTSSLDNQAGAIKAGKNAQLAITQQLDNRQRGIIGATGDLTLQADRILNQQGKLITN
HEEEECCCCCCCCCEECCCCCEEEEEECCCCCCCCEEECCCCEEEEHHHHHCCCCCEEEC
GHGRLTATDIDNRHGQIAGGSSLRLHTLRLNNSDDGQIQSGGDMALHASYLLNRETVDNG
CCCEEEEEECCCCCCEEECCCCEEEEEEEECCCCCCCEECCCCEEEEEEHHCCCCCCCCC
GDQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]