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The map label for this gene is hycD [H]

Identifier: 238921131

GI number: 238921131

Start: 3151151

End: 3152089

Strand: Direct

Name: hycD [H]

Synonym: NT01EI_3272

Alternate gene names: 238921131

Gene position: 3151151-3152089 (Clockwise)

Preceding gene: 238921130

Following gene: 238921132

Centisome position: 82.66

GC content: 64.0

Gene sequence:

>939_bases
ATGATGAGTGCACTTTCCATTTTCGCCCTGGCCTTGGGCCAGGCGCTGATCCTACTGGCGCTGGCGCCGCTGGCCAGCGG
TATCTCGCGCGTACTGCGGGCGCGCATGCACAGCCGACAAGGTCCCGGTCTCCTGCAGGAGTACCGCGATATCGCCAAGC
TGCTGCGACGCCAGAATATCGCGCCACAGTGCAGCGGTGCGCTGTTCCAGATGATGCCCTATATCATGGTCGGCACCATG
CTGACCATCGCCAGCGCCCTGCCGATGGTCACCCGCAGCACGCCGCTGCCGGGGCTGGGCGACGTCATTACCCTGGTCTA
TCTGTTCGCCGTCGCCCGCTTTTTCTTCATTCTGGCGGGGCTGGACACCGGCAGCCCGTTCAGCGCCATCGGTGCCAGCC
GTGAGTCTCTGCTGGGCATTCTGGTCGAACCGATCCTGATGCTCGGGCTGTGGGTAACTGCGCTGCTGGCCGGCTCCAGC
AACCTGGGGCTGATGGGTGATTATGTGTATGACTGGCATCAGCACGCCTCGCTGGCGCTGGGCCTGGCGCTGCTGGCCTG
CGCCTTCGCCACCTTTATTGAAATGGGCAAGCTGCCGTTCGATCTGGCCGAGGCCGAGCAGGAGCTGCAGGAGGGGCCGC
TGACGGAGTATGCCGGCTGCGCGCTGGGTGTCCTCAAGCTGGGCATCAGTCTAAAGCAGCTGGTGGTGCTGCAGCTGTTT
ATCGCGGTGTTCATCCCCTGGGGGCAGAGCACCACCCTGAGCGGTGGCGCCCTGCTGCTGGCACTGGCCATCGCGCTGAT
CAAGCTGCTGATCGGCATCGTCGTCATCTCCCTGCTGGAAAACAGCATGGCACGCCTGCGTTTCCTGAGGACTGGCTACA
CCACCTGGGCTGGCTTTGGCCTGGCGCTGCTGGCGTTCTTCTCTTGGCTGATCGCGTGA

Upstream 100 bases:

>100_bases
TGGACTGCTGAGCGAGGGCGCCCTGCGTGTCTACCCGGTACTGGCACTGTGCGAACTGGCGCTGCTGCTGGTTGCCGTGT
TCTCCTGAGGAGATGATGTG

Downstream 100 bases:

>100_bases
GGCGAACCATGACATCCATCGCCACGACGACCCGTTTTTCCTTTTTTGGCACAACCCATGAGGCCGCAAAGTAAAATGAC
ACAACACACCGGACAACACT

Product: hydrogenase-4 component C

Products: NA

Alternate protein names: FHL subunit 4; Hydrogenase 3 component D [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MMSALSIFALALGQALILLALAPLASGISRVLRARMHSRQGPGLLQEYRDIAKLLRRQNIAPQCSGALFQMMPYIMVGTM
LTIASALPMVTRSTPLPGLGDVITLVYLFAVARFFFILAGLDTGSPFSAIGASRESLLGILVEPILMLGLWVTALLAGSS
NLGLMGDYVYDWHQHASLALGLALLACAFATFIEMGKLPFDLAEAEQELQEGPLTEYAGCALGVLKLGISLKQLVVLQLF
IAVFIPWGQSTTLSGGALLLALAIALIKLLIGIVVISLLENSMARLRFLRTGYTTWAGFGLALLAFFSWLIA

Sequences:

>Translated_312_residues
MMSALSIFALALGQALILLALAPLASGISRVLRARMHSRQGPGLLQEYRDIAKLLRRQNIAPQCSGALFQMMPYIMVGTM
LTIASALPMVTRSTPLPGLGDVITLVYLFAVARFFFILAGLDTGSPFSAIGASRESLLGILVEPILMLGLWVTALLAGSS
NLGLMGDYVYDWHQHASLALGLALLACAFATFIEMGKLPFDLAEAEQELQEGPLTEYAGCALGVLKLGISLKQLVVLQLF
IAVFIPWGQSTTLSGGALLLALAIALIKLLIGIVVISLLENSMARLRFLRTGYTTWAGFGLALLAFFSWLIA
>Mature_312_residues
MMSALSIFALALGQALILLALAPLASGISRVLRARMHSRQGPGLLQEYRDIAKLLRRQNIAPQCSGALFQMMPYIMVGTM
LTIASALPMVTRSTPLPGLGDVITLVYLFAVARFFFILAGLDTGSPFSAIGASRESLLGILVEPILMLGLWVTALLAGSS
NLGLMGDYVYDWHQHASLALGLALLACAFATFIEMGKLPFDLAEAEQELQEGPLTEYAGCALGVLKLGISLKQLVVLQLF
IAVFIPWGQSTTLSGGALLLALAIALIKLLIGIVVISLLENSMARLRFLRTGYTTWAGFGLALLAFFSWLIA

Specific function: Hydrogen metabolism; FHL pathway. [C]

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI1789077, Length=299, Percent_Identity=67.5585284280936, Blast_Score=410, Evalue=1e-116,
Organism=Escherichia coli, GI87082115, Length=307, Percent_Identity=55.0488599348534, Blast_Score=293, Evalue=1e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: NA

Molecular weight: Translated: 33401; Mature: 33401

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00667 COMPLEX1_ND1_1 ; PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSALSIFALALGQALILLALAPLASGISRVLRARMHSRQGPGLLQEYRDIAKLLRRQNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
APQCSGALFQMMPYIMVGTMLTIASALPMVTRSTPLPGLGDVITLVYLFAVARFFFILAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
LDTGSPFSAIGASRESLLGILVEPILMLGLWVTALLAGSSNLGLMGDYVYDWHQHASLAL
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
GLALLACAFATFIEMGKLPFDLAEAEQELQEGPLTEYAGCALGVLKLGISLKQLVVLQLF
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IAVFIPWGQSTTLSGGALLLALAIALIKLLIGIVVISLLENSMARLRFLRTGYTTWAGFG
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LALLAFFSWLIA
HHHHHHHHHHHC
>Mature Secondary Structure
MMSALSIFALALGQALILLALAPLASGISRVLRARMHSRQGPGLLQEYRDIAKLLRRQNI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
APQCSGALFQMMPYIMVGTMLTIASALPMVTRSTPLPGLGDVITLVYLFAVARFFFILAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
LDTGSPFSAIGASRESLLGILVEPILMLGLWVTALLAGSSNLGLMGDYVYDWHQHASLAL
CCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
GLALLACAFATFIEMGKLPFDLAEAEQELQEGPLTEYAGCALGVLKLGISLKQLVVLQLF
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IAVFIPWGQSTTLSGGALLLALAIALIKLLIGIVVISLLENSMARLRFLRTGYTTWAGFG
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
LALLAFFSWLIA
HHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2187144; 9278503 [H]