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The map label for this gene is hycC [H]

Identifier: 238921130

GI number: 238921130

Start: 3149237

End: 3151138

Strand: Direct

Name: hycC [H]

Synonym: NT01EI_3271

Alternate gene names: 238921130

Gene position: 3149237-3151138 (Clockwise)

Preceding gene: 238921129

Following gene: 238921131

Centisome position: 82.61

GC content: 67.3

Gene sequence:

>1902_bases
ATGAGTATTCTGCAGCTGTTTAATCTGATGCTGGCGCTGTATCTGTGCAGCGCCATCATCGCGCTGGCATTCAGCGGTAT
CGGCCGACTGGGCGCCCACATCGCCGCTGTCGGCGGGCTACTGGCCGGCCTCTGCGGCAGCGTTGCCGCCGCCGCGCTCC
TACTGCAGTCGCCGCTGCTTCCGCCTACCGCACTGATCGTTAATCGCCTGCCGGTACTGTTCAGCCCGCTGAATAACCTG
ATGCTGCTGCTCACTTCGCTGATCAGTCTGCTGTGCGCGCTGTCCGCTTTTAGCGTCTCCCGGCACGACACCGGTAAAGC
CGCGCGCAGCGGCTGTCTGATGAACCTGCTGAGCGCTGCCATCAGTCTGCTGGTGGTATCGAACGATGCGCCGACCTTTA
TGGTGATGCTGGAGCTGATGAGCCTGAGCGCCGCGCTGCTGGTCTGCCAGGGCGGCAGCGCCAAGGCGCGCCGCGCCGCC
GGACTGTACTGGCTGATGTCCCGCCTGGGCTCGCTGGCGCTGCTGCTCTGCTTCTGGCTGCTGTGGCGTGCCAGCGGCAC
CCTGCTGCTGAGCGGGTTCCATCTGGCCAGCCTCAGCCACGCGCAACAGAGTATCGTCCTGCTGCTCGGCCTGCTCGGCT
TTGGCATCGTCACCGGTCTGGTGCCGCTGCACGGCTGGATCCCGGAGCTGCACGCCAACGCCCCGGCCCCGGCGGCCACG
CTATTCGCCAGCGTCATGCTCAAGATCGGCCTGTTCGGCCTGCTGAAACTCAGCATCGACTGGCTCGGTGTCCCACCGCT
GTGGTGGGGGCTGCTGCTGCTGTGCTGTGGCGCCCTCACCGCCTTTATCGGCGGACTATACGCTCTGGCGGAGCACGATC
TGCGCCGCCTGCTGGCCTATCACACCGTGGAAAACAGCGGCATCATCCTGCTCGGCCTGTCGGCCTGCGTCATCGGCGTC
GCGCTGGGCAGTCCGCTGCTGGCGGTGATGGGGCTGCTGGCCGGGCTGTTCCACCTGATCAACCACACCCTGTTTAAGGG
CGGGCTGTTCTTCGGCAACGGCGCCCTGATCCACGCCACCGGCCTGCACGACATCGATAAGATGGGGGGCCTGCTGCGCC
GTATGCCGCTACTGGGAGTGATGATGTTGCTGGCGCTGATGGCCATGGCGGCCCTGCCGCCGCTGAGCGGGTTTGTCAGT
GAATGGTACACCTACCAGTCCCTGTTCAGCCTGAGCCAGAACGGCGCCGGGGCCCTGCGTCTTCTGGCGCCGCTGGCGAT
GGTGGCATTGGCGATCGCCGGTGCGCTGGCGGTAATGTGCGTGGCCAAAATCTTCGGCATGACCTTCCTGGGGGCCCCGC
GCAGCGAGGCGGCGGCCAATCCGGGCACAGCGCCGTGGAACATGCTGCTGCCCCCCCTGCTGCTCAGCCTGTGCTGCGTG
CTGTTTGGGGTCGGCGCCCCCTGGGGCGTTCCCACGCTGCTGCGCCTCAGCGCGCAGGTGCTGCAGCTGGCCATCGGCAG
CGATGCGCTGACGATGGGCGCCATCATGTCGCCGGGCAGCAGTAACCTGACCCTGCTGTCGCCGCCACTGATGACCCTGC
TGTTGCTGGCCCTCCCGCTGCTGCCGCTGCTGCTGGCCACCCTGTACCGCGGCAGCCGCCTGCCGGCGCGCCGCCACGGC
GACGCCTGGACCTGCGGCTACGGCCATGAGGCGGGCATGGTGGTGACCGCCGGTGGTTTTGCCCAGCCGCTGCGCGTCCT
GTTCTCCCCGCTGTTTGCCCTGCGTCGGGTCTGCAATCCGGCACCGCTGTGCGGTGGACTGCTGAGCGAGGGCGCCCTGC
GTGTCTACCCGGTACTGGCACTGTGCGAACTGGCGCTGCTGCTGGTTGCCGTGTTCTCCTGA

Upstream 100 bases:

>100_bases
GCCTGGAGGATGCCAGCGCCGCCAAACGCCTGAACGTACTCGATGCCCAGCGCGCCGACCTGCTGGCTCTCGCTCGCTTA
TCCGGGGGAAATGACGCCCT

Downstream 100 bases:

>100_bases
GGAGATGATGTGATGATGAGTGCACTTTCCATTTTCGCCCTGGCCTTGGGCCAGGCGCTGATCCTACTGGCGCTGGCGCC
GCTGGCCAGCGGTATCTCGC

Product: hydrogenase-4 component B

Products: NA

Alternate protein names: FHL subunit 3; Hydrogenase-3 component C [H]

Number of amino acids: Translated: 633; Mature: 632

Protein sequence:

>633_residues
MSILQLFNLMLALYLCSAIIALAFSGIGRLGAHIAAVGGLLAGLCGSVAAAALLLQSPLLPPTALIVNRLPVLFSPLNNL
MLLLTSLISLLCALSAFSVSRHDTGKAARSGCLMNLLSAAISLLVVSNDAPTFMVMLELMSLSAALLVCQGGSAKARRAA
GLYWLMSRLGSLALLLCFWLLWRASGTLLLSGFHLASLSHAQQSIVLLLGLLGFGIVTGLVPLHGWIPELHANAPAPAAT
LFASVMLKIGLFGLLKLSIDWLGVPPLWWGLLLLCCGALTAFIGGLYALAEHDLRRLLAYHTVENSGIILLGLSACVIGV
ALGSPLLAVMGLLAGLFHLINHTLFKGGLFFGNGALIHATGLHDIDKMGGLLRRMPLLGVMMLLALMAMAALPPLSGFVS
EWYTYQSLFSLSQNGAGALRLLAPLAMVALAIAGALAVMCVAKIFGMTFLGAPRSEAAANPGTAPWNMLLPPLLLSLCCV
LFGVGAPWGVPTLLRLSAQVLQLAIGSDALTMGAIMSPGSSNLTLLSPPLMTLLLLALPLLPLLLATLYRGSRLPARRHG
DAWTCGYGHEAGMVVTAGGFAQPLRVLFSPLFALRRVCNPAPLCGGLLSEGALRVYPVLALCELALLLVAVFS

Sequences:

>Translated_633_residues
MSILQLFNLMLALYLCSAIIALAFSGIGRLGAHIAAVGGLLAGLCGSVAAAALLLQSPLLPPTALIVNRLPVLFSPLNNL
MLLLTSLISLLCALSAFSVSRHDTGKAARSGCLMNLLSAAISLLVVSNDAPTFMVMLELMSLSAALLVCQGGSAKARRAA
GLYWLMSRLGSLALLLCFWLLWRASGTLLLSGFHLASLSHAQQSIVLLLGLLGFGIVTGLVPLHGWIPELHANAPAPAAT
LFASVMLKIGLFGLLKLSIDWLGVPPLWWGLLLLCCGALTAFIGGLYALAEHDLRRLLAYHTVENSGIILLGLSACVIGV
ALGSPLLAVMGLLAGLFHLINHTLFKGGLFFGNGALIHATGLHDIDKMGGLLRRMPLLGVMMLLALMAMAALPPLSGFVS
EWYTYQSLFSLSQNGAGALRLLAPLAMVALAIAGALAVMCVAKIFGMTFLGAPRSEAAANPGTAPWNMLLPPLLLSLCCV
LFGVGAPWGVPTLLRLSAQVLQLAIGSDALTMGAIMSPGSSNLTLLSPPLMTLLLLALPLLPLLLATLYRGSRLPARRHG
DAWTCGYGHEAGMVVTAGGFAQPLRVLFSPLFALRRVCNPAPLCGGLLSEGALRVYPVLALCELALLLVAVFS
>Mature_632_residues
SILQLFNLMLALYLCSAIIALAFSGIGRLGAHIAAVGGLLAGLCGSVAAAALLLQSPLLPPTALIVNRLPVLFSPLNNLM
LLLTSLISLLCALSAFSVSRHDTGKAARSGCLMNLLSAAISLLVVSNDAPTFMVMLELMSLSAALLVCQGGSAKARRAAG
LYWLMSRLGSLALLLCFWLLWRASGTLLLSGFHLASLSHAQQSIVLLLGLLGFGIVTGLVPLHGWIPELHANAPAPAATL
FASVMLKIGLFGLLKLSIDWLGVPPLWWGLLLLCCGALTAFIGGLYALAEHDLRRLLAYHTVENSGIILLGLSACVIGVA
LGSPLLAVMGLLAGLFHLINHTLFKGGLFFGNGALIHATGLHDIDKMGGLLRRMPLLGVMMLLALMAMAALPPLSGFVSE
WYTYQSLFSLSQNGAGALRLLAPLAMVALAIAGALAVMCVAKIFGMTFLGAPRSEAAANPGTAPWNMLLPPLLLSLCCVL
FGVGAPWGVPTLLRLSAQVLQLAIGSDALTMGAIMSPGSSNLTLLSPPLMTLLLLALPLLPLLLATLYRGSRLPARRHGD
AWTCGYGHEAGMVVTAGGFAQPLRVLFSPLFALRRVCNPAPLCGGLLSEGALRVYPVLALCELALLLVAVFS

Specific function: Hydrogen metabolism; FHL pathway. [C]

COG id: COG0651

COG function: function code CP; Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 4 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=240, Percent_Identity=29.5833333333333, Blast_Score=86, Evalue=1e-16,
Organism=Escherichia coli, GI2367154, Length=633, Percent_Identity=43.7598736176935, Blast_Score=438, Evalue=1e-124,
Organism=Escherichia coli, GI1788827, Length=608, Percent_Identity=42.2697368421053, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI1788831, Length=355, Percent_Identity=28.169014084507, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788829, Length=373, Percent_Identity=28.1501340482574, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788613, Length=336, Percent_Identity=25.8928571428571, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788614, Length=329, Percent_Identity=26.7477203647416, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR003918 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: NA

Molecular weight: Translated: 66088; Mature: 65957

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILQLFNLMLALYLCSAIIALAFSGIGRLGAHIAAVGGLLAGLCGSVAAAALLLQSPLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PPTALIVNRLPVLFSPLNNLMLLLTSLISLLCALSAFSVSRHDTGKAARSGCLMNLLSAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ISLLVVSNDAPTFMVMLELMSLSAALLVCQGGSAKARRAAGLYWLMSRLGSLALLLCFWL
HHHHHCCCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LWRASGTLLLSGFHLASLSHAQQSIVLLLGLLGFGIVTGLVPLHGWIPELHANAPAPAAT
HHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHH
LFASVMLKIGLFGLLKLSIDWLGVPPLWWGLLLLCCGALTAFIGGLYALAEHDLRRLLAY
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTVENSGIILLGLSACVIGVALGSPLLAVMGLLAGLFHLINHTLFKGGLFFGNGALIHAT
HHCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEC
GLHDIDKMGGLLRRMPLLGVMMLLALMAMAALPPLSGFVSEWYTYQSLFSLSQNGAGALR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
LLAPLAMVALAIAGALAVMCVAKIFGMTFLGAPRSEAAANPGTAPWNMLLPPLLLSLCCV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LFGVGAPWGVPTLLRLSAQVLQLAIGSDALTMGAIMSPGSSNLTLLSPPLMTLLLLALPL
HHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHH
LPLLLATLYRGSRLPARRHGDAWTCGYGHEAGMVVTAGGFAQPLRVLFSPLFALRRVCNP
HHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCC
APLCGGLLSEGALRVYPVLALCELALLLVAVFS
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SILQLFNLMLALYLCSAIIALAFSGIGRLGAHIAAVGGLLAGLCGSVAAAALLLQSPLL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PPTALIVNRLPVLFSPLNNLMLLLTSLISLLCALSAFSVSRHDTGKAARSGCLMNLLSAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
ISLLVVSNDAPTFMVMLELMSLSAALLVCQGGSAKARRAAGLYWLMSRLGSLALLLCFWL
HHHHHCCCCCCHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LWRASGTLLLSGFHLASLSHAQQSIVLLLGLLGFGIVTGLVPLHGWIPELHANAPAPAAT
HHHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHH
LFASVMLKIGLFGLLKLSIDWLGVPPLWWGLLLLCCGALTAFIGGLYALAEHDLRRLLAY
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HTVENSGIILLGLSACVIGVALGSPLLAVMGLLAGLFHLINHTLFKGGLFFGNGALIHAT
HHCCCCCEEEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEEEC
GLHDIDKMGGLLRRMPLLGVMMLLALMAMAALPPLSGFVSEWYTYQSLFSLSQNGAGALR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHH
LLAPLAMVALAIAGALAVMCVAKIFGMTFLGAPRSEAAANPGTAPWNMLLPPLLLSLCCV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LFGVGAPWGVPTLLRLSAQVLQLAIGSDALTMGAIMSPGSSNLTLLSPPLMTLLLLALPL
HHCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHH
LPLLLATLYRGSRLPARRHGDAWTCGYGHEAGMVVTAGGFAQPLRVLFSPLFALRRVCNP
HHHHHHHHHCCCCCCCCCCCCCEECCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHCCC
APLCGGLLSEGALRVYPVLALCELALLLVAVFS
CCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2187144; 9278503 [H]