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The map label for this gene is uxaC

Identifier: 238916837

GI number: 238916837

Start: 915413

End: 916819

Strand: Reverse

Name: uxaC

Synonym: EUBELI_00905

Alternate gene names: 238916837

Gene position: 916819-915413 (Counterclockwise)

Preceding gene: 238916838

Following gene: 238916727

Centisome position: 42.76

GC content: 40.65

Gene sequence:

>1407_bases
ATGAAACAGTTCATGGACAAAGACTTTTTACTTTCAACTCCAACAGCTCAGCATTTATTCCACGATTATGCAGCTAAGAT
GCCAATACTTGACTATCACTGCCATATCAACCCTAGAGAAATCGCTGAAGACAGAAAGTTTGAGAACATCACACAGGTAT
GGCTTGGTGGCGATCATTACAAGTGGCGTCAGATGAGAACTAACGGTGTTGATGAGAAGTACATCACAGGTGATGCTTCT
GACCGCGAGAAGTTCCAGAAATGGGCTGAGACTCTTGAGATGGCTATTGGTAACCCACTTTATCACTGGAGCCACCTTGA
ACTTCAGAGATACTTCGGATACAACGGTATTCTCAACGGCGACACAGCTGAGGAAGTATGGAATCTCTGTAATGCAAAGC
TTCAGGAAGATTCTATGTCAGTTCGTAACCTTATCAAGCAGTCAAATGTTACATTAATCTGTACAACAGATGATCCTGTT
GACTCACTTGAGTGGCATCAGGTTCTTAAGGATGATAAGACATTTGACGTACAGGTACTTCCTGCATGGAGACCTGACAA
GGCTATGAACATTGAAAAGCCTGAATATCTTGATTATCTTGAGACATTATCTAATGTAAGCGGAATTAAAGTTAATTCAT
TTGCTTCATTAATAGATGCTCTTAAAAACCGTATGGATTTCTTTGCTTCTATGGGATGCTCAGTATCTGATCACGCTCTT
GAGTATGTAATGTACAAGCCATACACAGAAGAAGAAATCGAAGCAATCTTTGCTAAGAGATTCTCAGGTTCTGCTATCAC
TACAGAAGAGATGAACAAGTTCAAGACAGCATTCATGGTATCTGTAGGTAAAGAATACAACAAGCGTAACTGGGTAATGC
AGATACATTATGGTACAATACGTGATAACAACAGATTCCGTTATGACCAGTTAGGTCCAGATACTGGATTTGACTGCATT
AACACATATGACTGCTCTGCTGAGATGGCTCAGTTCCTTAACGCACTTAATGCTACAGATGAGCTTCCTAAGACAATCAT
TTACTCACTTAACCCTTCAGTTAACGCTGCTATCGGAACAGTTATCGGATGCTTCCAGGATTCTAAGGCTGTTGGCAAGA
TTCAGCAGGGTTCAGCTTGGTGGTTCAACGATCATAAGGTTGGTATGACTAACCAGATGACAAGCCTTGCTAACTTAAGT
CTTCTTGGTAACTTCATCGGAATGCTTACAGATTCAAGAAGCTTCCTCTCATACACAAGACATGAGTACTTCAGAAGAAT
CATGTGCGAGCTTATCGGTGGATGGGTAGAGAATGGTGAATATCCAGCAGATGAGAAGGCATTAAAGAAGATTGTTGAAG
GTATCTCATACAACAACGCTGTAAGATACTTTGGATTTGATCTTTAA

Upstream 100 bases:

>100_bases
GGTTTTATCCGGTGAAGATGCTGATAATCACAGTATCATCGCCGCTGATATAATAAAACGCAACACAACAATATTTTAAT
TCACAGGAGGATTATGAATC

Downstream 100 bases:

>100_bases
TTAGTACCCGAAAAGATAAAAGCCGCTGCCACAATATTTGTGGTAACGGCTTTTTATTATATCTCTTATTACTTTTTATT
CCTTGTCTTTTCCATTACAT

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MKQFMDKDFLLSTPTAQHLFHDYAAKMPILDYHCHINPREIAEDRKFENITQVWLGGDHYKWRQMRTNGVDEKYITGDAS
DREKFQKWAETLEMAIGNPLYHWSHLELQRYFGYNGILNGDTAEEVWNLCNAKLQEDSMSVRNLIKQSNVTLICTTDDPV
DSLEWHQVLKDDKTFDVQVLPAWRPDKAMNIEKPEYLDYLETLSNVSGIKVNSFASLIDALKNRMDFFASMGCSVSDHAL
EYVMYKPYTEEEIEAIFAKRFSGSAITTEEMNKFKTAFMVSVGKEYNKRNWVMQIHYGTIRDNNRFRYDQLGPDTGFDCI
NTYDCSAEMAQFLNALNATDELPKTIIYSLNPSVNAAIGTVIGCFQDSKAVGKIQQGSAWWFNDHKVGMTNQMTSLANLS
LLGNFIGMLTDSRSFLSYTRHEYFRRIMCELIGGWVENGEYPADEKALKKIVEGISYNNAVRYFGFDL

Sequences:

>Translated_468_residues
MKQFMDKDFLLSTPTAQHLFHDYAAKMPILDYHCHINPREIAEDRKFENITQVWLGGDHYKWRQMRTNGVDEKYITGDAS
DREKFQKWAETLEMAIGNPLYHWSHLELQRYFGYNGILNGDTAEEVWNLCNAKLQEDSMSVRNLIKQSNVTLICTTDDPV
DSLEWHQVLKDDKTFDVQVLPAWRPDKAMNIEKPEYLDYLETLSNVSGIKVNSFASLIDALKNRMDFFASMGCSVSDHAL
EYVMYKPYTEEEIEAIFAKRFSGSAITTEEMNKFKTAFMVSVGKEYNKRNWVMQIHYGTIRDNNRFRYDQLGPDTGFDCI
NTYDCSAEMAQFLNALNATDELPKTIIYSLNPSVNAAIGTVIGCFQDSKAVGKIQQGSAWWFNDHKVGMTNQMTSLANLS
LLGNFIGMLTDSRSFLSYTRHEYFRRIMCELIGGWVENGEYPADEKALKKIVEGISYNNAVRYFGFDL
>Mature_468_residues
MKQFMDKDFLLSTPTAQHLFHDYAAKMPILDYHCHINPREIAEDRKFENITQVWLGGDHYKWRQMRTNGVDEKYITGDAS
DREKFQKWAETLEMAIGNPLYHWSHLELQRYFGYNGILNGDTAEEVWNLCNAKLQEDSMSVRNLIKQSNVTLICTTDDPV
DSLEWHQVLKDDKTFDVQVLPAWRPDKAMNIEKPEYLDYLETLSNVSGIKVNSFASLIDALKNRMDFFASMGCSVSDHAL
EYVMYKPYTEEEIEAIFAKRFSGSAITTEEMNKFKTAFMVSVGKEYNKRNWVMQIHYGTIRDNNRFRYDQLGPDTGFDCI
NTYDCSAEMAQFLNALNATDELPKTIIYSLNPSVNAAIGTVIGCFQDSKAVGKIQQGSAWWFNDHKVGMTNQMTSLANLS
LLGNFIGMLTDSRSFLSYTRHEYFRRIMCELIGGWVENGEYPADEKALKKIVEGISYNNAVRYFGFDL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family

Homologues:

Organism=Escherichia coli, GI2367192, Length=469, Percent_Identity=53.5181236673774, Blast_Score=540, Evalue=1e-155,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UXAC_EUBE2 (C4Z5P8)

Other databases:

- EMBL:   CP001104
- RefSeq:   YP_002930354.1
- GeneID:   7958399
- GenomeReviews:   CP001104_GR
- KEGG:   eel:EUBELI_00905
- OMA:   DYHCHIN
- ProtClustDB:   CLSK2540985
- HAMAP:   MF_00675
- InterPro:   IPR003766
- InterPro:   IPR023177
- Gene3D:   G3DSA:1.10.2020.10

Pfam domain/function: PF02614 UxaC

EC number: =5.3.1.12

Molecular weight: Translated: 53930; Mature: 53930

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQFMDKDFLLSTPTAQHLFHDYAAKMPILDYHCHINPREIAEDRKFENITQVWLGGDHY
CCCCCCCCCEECCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHEECCCCH
KWRQMRTNGVDEKYITGDASDREKFQKWAETLEMAIGNPLYHWSHLELQRYFGYNGILNG
HHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCC
DTAEEVWNLCNAKLQEDSMSVRNLIKQSNVTLICTTDDPVDSLEWHQVLKDDKTFDVQVL
CCHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEE
PAWRPDKAMNIEKPEYLDYLETLSNVSGIKVNSFASLIDALKNRMDFFASMGCSVSDHAL
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
EYVMYKPYTEEEIEAIFAKRFSGSAITTEEMNKFKTAFMVSVGKEYNKRNWVMQIHYGTI
HHEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEE
RDNNRFRYDQLGPDTGFDCINTYDCSAEMAQFLNALNATDELPKTIIYSLNPSVNAAIGT
ECCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHCCHHEEEECCCCCHHHHHH
VIGCFQDSKAVGKIQQGSAWWFNDHKVGMTNQMTSLANLSLLGNFIGMLTDSRSFLSYTR
HHHHHCCCHHHCCEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HEYFRRIMCELIGGWVENGEYPADEKALKKIVEGISYNNAVRYFGFDL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCC
>Mature Secondary Structure
MKQFMDKDFLLSTPTAQHLFHDYAAKMPILDYHCHINPREIAEDRKFENITQVWLGGDHY
CCCCCCCCCEECCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHEECCCCH
KWRQMRTNGVDEKYITGDASDREKFQKWAETLEMAIGNPLYHWSHLELQRYFGYNGILNG
HHHHHHCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCC
DTAEEVWNLCNAKLQEDSMSVRNLIKQSNVTLICTTDDPVDSLEWHQVLKDDKTFDVQVL
CCHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHCCCCCEEEEEE
PAWRPDKAMNIEKPEYLDYLETLSNVSGIKVNSFASLIDALKNRMDFFASMGCSVSDHAL
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
EYVMYKPYTEEEIEAIFAKRFSGSAITTEEMNKFKTAFMVSVGKEYNKRNWVMQIHYGTI
HHEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEE
RDNNRFRYDQLGPDTGFDCINTYDCSAEMAQFLNALNATDELPKTIIYSLNPSVNAAIGT
ECCCCEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHCCHHEEEECCCCCHHHHHH
VIGCFQDSKAVGKIQQGSAWWFNDHKVGMTNQMTSLANLSLLGNFIGMLTDSRSFLSYTR
HHHHHCCCHHHCCEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
HEYFRRIMCELIGGWVENGEYPADEKALKKIVEGISYNNAVRYFGFDL
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA