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The map label for this gene is ccpA [H]

Identifier: 238916838

GI number: 238916838

Start: 916841

End: 917851

Strand: Reverse

Name: ccpA [H]

Synonym: EUBELI_00906

Alternate gene names: 238916838

Gene position: 917851-916841 (Counterclockwise)

Preceding gene: 238916844

Following gene: 238916837

Centisome position: 42.81

GC content: 36.89

Gene sequence:

>1011_bases
ATGAATATTAATATATATGATGTTTCTAAAAAAGCTGGTGTGTCCATAGCAACTGTCTCAAGAGTACTTAACGGCAACGC
CAAAGTTTCCGAGAAGACAAGAGACAAGGTTATTAATGCAATGAAAGAATTAGACTACACTCCTAATGTATTTGCAAGAG
GATTAGGTCTTAATACTATGAAGACAATTGGCATTATGTGCATAGATTCATCTGATATATACCTTGCCAACGCTGTTTAC
TACCTTGAACAGGAGCTTCGTAAATACAACTACGATTCTATTCTTTGCTGCACCGGTAAAGATTACAATAATAAGAAGAA
TTATCTCGAACTTCTTTTAAGTAAAAGAGTTGACGGAATTATTCTTGCCGGTTCACAGTTTGTAGAAAATACCAGTGAAC
ATAACAACGACTACATTATTAATGCAGCTAAAGATGTTCCTATAGTTCTGGTCAACGGCTATCTGGACGCTGACAACATT
TATTCAGTAATGTGCAATGATGAAGAAGCTGTATACAATGCAACAAAACTCTTGATAAATAATTCACATCGTAATATAGT
TTACTTATATACTAGTACTTCATACAGTGGCATGAATAAGTACCGCGGCTATCTTAAAGCAATTAATGAAGCCGGTATTA
CTCTCCCGGATGAATTCCATCATCTGTGTGGCAAGAACATATCTCATGCCAGAGATTATCTTACATATCTGTATGATAAA
GGTATGAAGTTTGATGCCGTTATGACATCTGATGACTCTATCGCTGCCGGTGCTGTCAAGTTTGCACATACCCACGGAAC
CAGAATTCCTGAGGATTTAGAGGTTATTGGATATAATAACTCTGTTCTTTCATTATGTACAGAACCTGAGCTTACCTCTA
TTGACAGCAAGGTTGAGGAACTATCCTCATGCGCGGTAAGCGTGCTTATGAAGGTTTTATCCGGTGAAGATGCTGATAAT
CACAGTATCATCGCCGCTGATATAATAAAACGCAACACAACAATATTTTAA

Upstream 100 bases:

>100_bases
GTATAATTCATTTATCAATATGTAAGCGCTTACATTTATTTATTTTTTATCAATTTCAGTTAAGCGTTACATTTACAATC
GTCAAGAGATGAGGTCGCAC

Downstream 100 bases:

>100_bases
TTCACAGGAGGATTATGAATCATGAAACAGTTCATGGACAAAGACTTTTTACTTTCAACTCCAACAGCTCAGCATTTATT
CCACGATTATGCAGCTAAGA

Product: alanine racemase

Products: NA

Alternate protein names: Glucose-resistance amylase regulator [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MNINIYDVSKKAGVSIATVSRVLNGNAKVSEKTRDKVINAMKELDYTPNVFARGLGLNTMKTIGIMCIDSSDIYLANAVY
YLEQELRKYNYDSILCCTGKDYNNKKNYLELLLSKRVDGIILAGSQFVENTSEHNNDYIINAAKDVPIVLVNGYLDADNI
YSVMCNDEEAVYNATKLLINNSHRNIVYLYTSTSYSGMNKYRGYLKAINEAGITLPDEFHHLCGKNISHARDYLTYLYDK
GMKFDAVMTSDDSIAAGAVKFAHTHGTRIPEDLEVIGYNNSVLSLCTEPELTSIDSKVEELSSCAVSVLMKVLSGEDADN
HSIIAADIIKRNTTIF

Sequences:

>Translated_336_residues
MNINIYDVSKKAGVSIATVSRVLNGNAKVSEKTRDKVINAMKELDYTPNVFARGLGLNTMKTIGIMCIDSSDIYLANAVY
YLEQELRKYNYDSILCCTGKDYNNKKNYLELLLSKRVDGIILAGSQFVENTSEHNNDYIINAAKDVPIVLVNGYLDADNI
YSVMCNDEEAVYNATKLLINNSHRNIVYLYTSTSYSGMNKYRGYLKAINEAGITLPDEFHHLCGKNISHARDYLTYLYDK
GMKFDAVMTSDDSIAAGAVKFAHTHGTRIPEDLEVIGYNNSVLSLCTEPELTSIDSKVEELSSCAVSVLMKVLSGEDADN
HSIIAADIIKRNTTIF
>Mature_336_residues
MNINIYDVSKKAGVSIATVSRVLNGNAKVSEKTRDKVINAMKELDYTPNVFARGLGLNTMKTIGIMCIDSSDIYLANAVY
YLEQELRKYNYDSILCCTGKDYNNKKNYLELLLSKRVDGIILAGSQFVENTSEHNNDYIINAAKDVPIVLVNGYLDADNI
YSVMCNDEEAVYNATKLLINNSHRNIVYLYTSTSYSGMNKYRGYLKAINEAGITLPDEFHHLCGKNISHARDYLTYLYDK
GMKFDAVMTSDDSIAAGAVKFAHTHGTRIPEDLEVIGYNNSVLSLCTEPELTSIDSKVEELSSCAVSVLMKVLSGEDADN
HSIIAADIIKRNTTIF

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (AmyE) and the acetyl-coenzyme A synthetase (AcsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789068, Length=338, Percent_Identity=28.9940828402367, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1787948, Length=334, Percent_Identity=29.0419161676647, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1788474, Length=322, Percent_Identity=28.2608695652174, Blast_Score=135, Evalue=4e-33,
Organism=Escherichia coli, GI1790194, Length=308, Percent_Identity=30.1948051948052, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1789202, Length=295, Percent_Identity=30.5084745762712, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790369, Length=332, Percent_Identity=25.9036144578313, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787580, Length=333, Percent_Identity=25.2252252252252, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI48994940, Length=313, Percent_Identity=25.8785942492013, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI1786540, Length=345, Percent_Identity=25.5072463768116, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1786268, Length=335, Percent_Identity=25.9701492537313, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787906, Length=258, Percent_Identity=26.7441860465116, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1790689, Length=331, Percent_Identity=23.8670694864048, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790715, Length=323, Percent_Identity=21.3622291021672, Blast_Score=75, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37384; Mature: 37384

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINIYDVSKKAGVSIATVSRVLNGNAKVSEKTRDKVINAMKELDYTPNVFARGLGLNTM
CCEEEEECCHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCH
KTIGIMCIDSSDIYLANAVYYLEQELRKYNYDSILCCTGKDYNNKKNYLELLLSKRVDGI
HEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEE
ILAGSQFVENTSEHNNDYIINAAKDVPIVLVNGYLDADNIYSVMCNDEEAVYNATKLLIN
EEECHHHHHCCCCCCCCEEEEECCCCCEEEEECEECCCCEEEEEECCCHHHHHHEEEEEE
NSHRNIVYLYTSTSYSGMNKYRGYLKAINEAGITLPDEFHHLCGKNISHARDYLTYLYDK
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHC
GMKFDAVMTSDDSIAAGAVKFAHTHGTRIPEDLEVIGYNNSVLSLCTEPELTSIDSKVEE
CCEEEEEEECCCCCHHHEEEEEECCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHH
LSSCAVSVLMKVLSGEDADNHSIIAADIIKRNTTIF
HHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCCC
>Mature Secondary Structure
MNINIYDVSKKAGVSIATVSRVLNGNAKVSEKTRDKVINAMKELDYTPNVFARGLGLNTM
CCEEEEECCHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCH
KTIGIMCIDSSDIYLANAVYYLEQELRKYNYDSILCCTGKDYNNKKNYLELLLSKRVDGI
HEEEEEEECCCCEEEHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHCCCEE
ILAGSQFVENTSEHNNDYIINAAKDVPIVLVNGYLDADNIYSVMCNDEEAVYNATKLLIN
EEECHHHHHCCCCCCCCEEEEECCCCCEEEEECEECCCCEEEEEECCCHHHHHHEEEEEE
NSHRNIVYLYTSTSYSGMNKYRGYLKAINEAGITLPDEFHHLCGKNISHARDYLTYLYDK
CCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHC
GMKFDAVMTSDDSIAAGAVKFAHTHGTRIPEDLEVIGYNNSVLSLCTEPELTSIDSKVEE
CCEEEEEEECCCCCHHHEEEEEECCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHH
LSSCAVSVLMKVLSGEDADNHSIIAADIIKRNTTIF
HHHHHHHHHHHHHCCCCCCCCCEEEEEHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1904524; 9387221; 9384377 [H]