Click here to switch to the map view.

The map label for this gene is allB [H]

Identifier: 238893473

GI number: 238893473

Start: 1319299

End: 1320660

Strand: Direct

Name: allB [H]

Synonym: KP1_1367

Alternate gene names: 238893473

Gene position: 1319299-1320660 (Clockwise)

Preceding gene: 238893472

Following gene: 238893474

Centisome position: 25.14

GC content: 56.09

Gene sequence:

>1362_bases
ATGTCTTTTGATTTAATCATTAAAAACGGCACTGTTATTCTGGAAAACGAATCCCGGGTAGTCGATATCGCGGTGAACGA
CGGTAAAATCGCTGCTATTGGTGAGCACCTGGGCGAGGCGAAGCAGGTCATGGATGCCACGGGTCTGATCGTTTCGCCGG
GCATGGTCGATGCGCATACGCATATCTCTGAACCTGGTCGTACCCACTGGGAAGGTTACGAAACCGGGACTCGCGCGGCG
GCAAAAGGCGGCATCACCACGATGATTGAAATGCCGCTGAATCAGCTACCGGCCACCGTTGACCGGCAGACCATTGAGCT
GAAATTCGACGCGGCGAAAGGCAAACTGACCATCGATGCCGCGCAGCTTGGCGGCCTGGTCTCTTATAACCTCGACCGAC
TGCATGAGCTGGATGAAGTGGGAGTGGTGGGATTCAAATGCTTCGTCGCCACCTGCGGTGACCGCGGGATCGATAACGAC
TTCCGCGACGTCAACGATTGGCAGTTCTTCAAAGGCATACAAAAGCTGGCCGAAATGAAGCAGACCGTGCTGGTGCACTG
CGAAAACGCGCTGATCTGCGACGAGCTAGGCGAAGAGGCGAAAAGGGAAGGCCGCGTGACGGCGCATGATTATGTAGCCT
CTCGGCCGGTCTTCACCGAAGTGGAAGCCATTCGCCGCGTTCTGTATCTGGCGAAAGTCGCCGGTTGCCGCTTGCATGTG
TGTCATGTCAGCAGCCCGGAAGGGGTAGCCGAAGTGACCCGCGCCCGTCAGGAAGGGCAGGATGTGACTTGTGAATCTTG
CCCGCACTACTTTGTACTGGATACCGATCAGTTTGCAGAGATCGGTACCTTGGCGAAGTGCTCTCCGCCGATCCGCGATG
CGGAAAACCAGAAAGGCATGTGGGAAAAGCTGTTCAACGGAGAAATCGACTGCCTGGTCTCCGACCATTCGCCGTGCCCA
CCGGAAATGAAGGCTGGCAATATCATGCAGGCCTGGGGCGGGATTGCCGGTCTGCAAAACTGCATGGACGTGATGTTCGA
TGAAGCGGTGCAGAAACGCGGTATGTCTCTGCCGCAGTTTGCCCGTCTGATGGCGACCAACGCCGCCGATATTTTCGGCC
TGAAGCATAAGGGCCGCATTGCCCCGGGTAAAGACGCCGACCTGGTGTTTATTCAGCCGAACAGCAGCTACGTTTTACGG
GCAGAAGACCTCGAATATCGCCACAAAGTCAGCCCTTACGTGGGTCGCAAGATTGGCGCTCGGATTGCTAAAACCATTCT
GCGCGGCGAGGTGATCTATGACATCGAACAGGGCTTCCCGCGCGAGCCGAAGGGGAAATTTATCCTTAAGCATCAGCAGT
AA

Upstream 100 bases:

>100_bases
TGGATGAAGCATTACCGGCCAAAGCCATTGTTATTGCGGCACGCAATGTCGCAGCAGAAGTATGGCGGCTGACCCATCTG
TACACATACAAGGAGTTATT

Downstream 100 bases:

>100_bases
CGGGCGAATAAAAAGTTGGGGATGGTTTGCTCCCTCTCTCTTTGGGAGAGGGCCGGGGTGAGGGCATTGGTGGGTACATT
TCCCCTCACCCTATCCCTCT

Product: allantoinase

Products: NA

Alternate protein names: Allantoin-utilizing enzyme [H]

Number of amino acids: Translated: 453; Mature: 452

Protein sequence:

>453_residues
MSFDLIIKNGTVILENESRVVDIAVNDGKIAAIGEHLGEAKQVMDATGLIVSPGMVDAHTHISEPGRTHWEGYETGTRAA
AKGGITTMIEMPLNQLPATVDRQTIELKFDAAKGKLTIDAAQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDND
FRDVNDWQFFKGIQKLAEMKQTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
CHVSSPEGVAEVTRARQEGQDVTCESCPHYFVLDTDQFAEIGTLAKCSPPIRDAENQKGMWEKLFNGEIDCLVSDHSPCP
PEMKAGNIMQAWGGIAGLQNCMDVMFDEAVQKRGMSLPQFARLMATNAADIFGLKHKGRIAPGKDADLVFIQPNSSYVLR
AEDLEYRHKVSPYVGRKIGARIAKTILRGEVIYDIEQGFPREPKGKFILKHQQ

Sequences:

>Translated_453_residues
MSFDLIIKNGTVILENESRVVDIAVNDGKIAAIGEHLGEAKQVMDATGLIVSPGMVDAHTHISEPGRTHWEGYETGTRAA
AKGGITTMIEMPLNQLPATVDRQTIELKFDAAKGKLTIDAAQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDND
FRDVNDWQFFKGIQKLAEMKQTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
CHVSSPEGVAEVTRARQEGQDVTCESCPHYFVLDTDQFAEIGTLAKCSPPIRDAENQKGMWEKLFNGEIDCLVSDHSPCP
PEMKAGNIMQAWGGIAGLQNCMDVMFDEAVQKRGMSLPQFARLMATNAADIFGLKHKGRIAPGKDADLVFIQPNSSYVLR
AEDLEYRHKVSPYVGRKIGARIAKTILRGEVIYDIEQGFPREPKGKFILKHQQ
>Mature_452_residues
SFDLIIKNGTVILENESRVVDIAVNDGKIAAIGEHLGEAKQVMDATGLIVSPGMVDAHTHISEPGRTHWEGYETGTRAAA
KGGITTMIEMPLNQLPATVDRQTIELKFDAAKGKLTIDAAQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDNDF
RDVNDWQFFKGIQKLAEMKQTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHVC
HVSSPEGVAEVTRARQEGQDVTCESCPHYFVLDTDQFAEIGTLAKCSPPIRDAENQKGMWEKLFNGEIDCLVSDHSPCPP
EMKAGNIMQAWGGIAGLQNCMDVMFDEAVQKRGMSLPQFARLMATNAADIFGLKHKGRIAPGKDADLVFIQPNSSYVLRA
EDLEYRHKVSPYVGRKIGARIAKTILRGEVIYDIEQGFPREPKGKFILKHQQ

Specific function: Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring [H]

COG id: COG0044

COG function: function code F; Dihydroorotase and related cyclic amidohydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHOase family. Allantoinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI4503375, Length=477, Percent_Identity=26.8343815513627, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI4503379, Length=462, Percent_Identity=26.4069264069264, Blast_Score=129, Evalue=4e-30,
Organism=Homo sapiens, GI4503051, Length=455, Percent_Identity=27.4725274725275, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI62422571, Length=455, Percent_Identity=27.9120879120879, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI19923821, Length=473, Percent_Identity=26.8498942917548, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI190194363, Length=467, Percent_Identity=27.6231263383298, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI4503377, Length=482, Percent_Identity=26.7634854771784, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI18105007, Length=421, Percent_Identity=24.4655581947743, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1786722, Length=453, Percent_Identity=91.6114790286976, Blast_Score=870, Evalue=0.0,
Organism=Escherichia coli, GI87082175, Length=460, Percent_Identity=28.9130434782609, Blast_Score=170, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17539558, Length=468, Percent_Identity=26.0683760683761, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71989490, Length=470, Percent_Identity=25.9574468085106, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI193204318, Length=380, Percent_Identity=25.5263157894737, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI86575075, Length=439, Percent_Identity=23.6902050113895, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322218, Length=469, Percent_Identity=33.2622601279318, Blast_Score=261, Evalue=2e-70,
Organism=Drosophila melanogaster, GI18859883, Length=430, Percent_Identity=34.8837209302326, Blast_Score=215, Evalue=4e-56,
Organism=Drosophila melanogaster, GI221377917, Length=471, Percent_Identity=26.1146496815287, Blast_Score=133, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24642586, Length=397, Percent_Identity=24.1813602015113, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI17137462, Length=466, Percent_Identity=25.5364806866953, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24644287, Length=318, Percent_Identity=26.7295597484277, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24644289, Length=238, Percent_Identity=26.4705882352941, Blast_Score=73, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017593
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.5 [H]

Molecular weight: Translated: 49996; Mature: 49865

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFDLIIKNGTVILENESRVVDIAVNDGKIAAIGEHLGEAKQVMDATGLIVSPGMVDAHT
CCEEEEEECCEEEEECCCEEEEEEECCCEEEEHHHHHHHHHHHHHHCCEEECCCCCCCCC
HISEPGRTHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRQTIELKFDAAKGKLTIDA
CCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCHHHCCCCCCCEEEEEEEECCCCEEEEEH
AQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGIQKLAEMK
HHHCCCCCCCHHHHHHHHHCCCCHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
HHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEE
CHVSSPEGVAEVTRARQEGQDVTCESCPHYFVLDTDQFAEIGTLAKCSPPIRDAENQKGM
EECCCCCHHHHHHHHHHCCCCCCHHCCCCEEEECCHHHHHHCCHHCCCCCCCCCCCCCCH
WEKLFNGEIDCLVSDHSPCPPEMKAGNIMQAWGGIAGLQNCMDVMFDEAVQKRGMSLPQF
HHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ARLMATNAADIFGLKHKGRIAPGKDADLVFIQPNSSYVLRAEDLEYRHKVSPYVGRKIGA
HHHHHCCCHHHEEECCCCCCCCCCCCCEEEECCCCCEEEEECCCCHHHHCCHHHHHHHHH
RIAKTILRGEVIYDIEQGFPREPKGKFILKHQQ
HHHHHHHHCCEEEEHHCCCCCCCCCCEEEECCC
>Mature Secondary Structure 
SFDLIIKNGTVILENESRVVDIAVNDGKIAAIGEHLGEAKQVMDATGLIVSPGMVDAHT
CEEEEEECCEEEEECCCEEEEEEECCCEEEEHHHHHHHHHHHHHHCCEEECCCCCCCCC
HISEPGRTHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRQTIELKFDAAKGKLTIDA
CCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCHHHCCCCCCCEEEEEEEECCCCEEEEEH
AQLGGLVSYNLDRLHELDEVGVVGFKCFVATCGDRGIDNDFRDVNDWQFFKGIQKLAEMK
HHHCCCCCCCHHHHHHHHHCCCCHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
QTVLVHCENALICDELGEEAKREGRVTAHDYVASRPVFTEVEAIRRVLYLAKVAGCRLHV
HHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEE
CHVSSPEGVAEVTRARQEGQDVTCESCPHYFVLDTDQFAEIGTLAKCSPPIRDAENQKGM
EECCCCCHHHHHHHHHHCCCCCCHHCCCCEEEECCHHHHHHCCHHCCCCCCCCCCCCCCH
WEKLFNGEIDCLVSDHSPCPPEMKAGNIMQAWGGIAGLQNCMDVMFDEAVQKRGMSLPQF
HHHHHCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
ARLMATNAADIFGLKHKGRIAPGKDADLVFIQPNSSYVLRAEDLEYRHKVSPYVGRKIGA
HHHHHCCCHHHEEECCCCCCCCCCCCCEEEECCCCCEEEEECCCCHHHHCCHHHHHHHHH
RIAKTILRGEVIYDIEQGFPREPKGKFILKHQQ
HHHHHHHHCCEEEEHHCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA