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The map label for this gene is aroE [H]

Identifier: 238893051

GI number: 238893051

Start: 872573

End: 873451

Strand: Reverse

Name: aroE [H]

Synonym: KP1_0890

Alternate gene names: 238893051

Gene position: 873451-872573 (Counterclockwise)

Preceding gene: 238893052

Following gene: 238893050

Centisome position: 16.64

GC content: 57.68

Gene sequence:

>879_bases
TTGAGGATTTTTGTCATGGCAGAACGTATTACTGGACACACTGAGCTGATTGGCCTGATCGCCACCCCGATTCGTCACAG
CATGTCGCCCACCATGCACAACGAGGCTTTCGCCTATCTCGGGCTGGACTACGTCTATCTCGCTTTTGAAGTCGGTAACC
AGGAGCTAAAAGACGTGGTGCAGGGCTTCCGGGCGATGAAGCTGCGCGGCTTTAACGTCTCTATGCCGAACAAAACCGAG
ATTTGCCAGTATCTCGATAAACTGTCGCCGGCGGCACAGCTGGTCGGGGCGGTCAATACCGTGGTCAACGACGACGGCGT
ACTGACCGGACATATCACCGATGGCACCGGCTACATGCGCGCCCTTAGCGAAGCCGGTATCGATATCATCGGCAAGAAGA
TGACCGTACTCGGCGCCGGCGGCGCGGCAACGGCGCTCTGCGTCCAGGCAGCACTGGATGGCGTGAAGGCGATCTCCATC
TTCAACCGCCGCGATAAATTCTTCGCCAACGCAGAAGAAACCGTGGCCAAGATCCGCCACAACACCGACTGCGAGATCCA
TCTGTTCGATCTCGACGATCATGACAAGCTGCGCGCCGAAATTGACAGCAGCGTGATCCTGACCAATGCCACCGGGGTCG
GCATGAAGCCGTTCGAAGGCCAGATGCTGCTACCTGACGACAGCTTCCTGCGTCCGGACCTGATCGTCTCCGACGTCGTC
TACAACCCGCGCAAAACCCACCTGCTGGAAGTGGCCGAGAAAAAAGGCTGCCGCACGCTGAACGGCCTGGGGATGATGCT
GTGGCAAGGCGCGCGCGCGTTCGAAATCTGGACGGGCAAACAGATGCCGGTTGATTACATCAAGAGCATTCTGTTCTAA

Upstream 100 bases:

>100_bases
TTATCGATGGCGTCCGCGAAGGCCGCAACGTACTGGATGCACTGGAAGACATGGGTGCGCTGGGCAGCCGCGAAGCACAA
CGAATTCCCTTTCTAACTTA

Downstream 100 bases:

>100_bases
GAGGCGAATGATGAAAAATAAATACATCCCTACTGCGGCAGGGCTGTACCTCAACTACCTGATCCACGGTATGGGGGTGC
TGTTAATCACCCTCAACATG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MRIFVMAERITGHTELIGLIATPIRHSMSPTMHNEAFAYLGLDYVYLAFEVGNQELKDVVQGFRAMKLRGFNVSMPNKTE
ICQYLDKLSPAAQLVGAVNTVVNDDGVLTGHITDGTGYMRALSEAGIDIIGKKMTVLGAGGAATALCVQAALDGVKAISI
FNRRDKFFANAEETVAKIRHNTDCEIHLFDLDDHDKLRAEIDSSVILTNATGVGMKPFEGQMLLPDDSFLRPDLIVSDVV
YNPRKTHLLEVAEKKGCRTLNGLGMMLWQGARAFEIWTGKQMPVDYIKSILF

Sequences:

>Translated_292_residues
MRIFVMAERITGHTELIGLIATPIRHSMSPTMHNEAFAYLGLDYVYLAFEVGNQELKDVVQGFRAMKLRGFNVSMPNKTE
ICQYLDKLSPAAQLVGAVNTVVNDDGVLTGHITDGTGYMRALSEAGIDIIGKKMTVLGAGGAATALCVQAALDGVKAISI
FNRRDKFFANAEETVAKIRHNTDCEIHLFDLDDHDKLRAEIDSSVILTNATGVGMKPFEGQMLLPDDSFLRPDLIVSDVV
YNPRKTHLLEVAEKKGCRTLNGLGMMLWQGARAFEIWTGKQMPVDYIKSILF
>Mature_292_residues
MRIFVMAERITGHTELIGLIATPIRHSMSPTMHNEAFAYLGLDYVYLAFEVGNQELKDVVQGFRAMKLRGFNVSMPNKTE
ICQYLDKLSPAAQLVGAVNTVVNDDGVLTGHITDGTGYMRALSEAGIDIIGKKMTVLGAGGAATALCVQAALDGVKAISI
FNRRDKFFANAEETVAKIRHNTDCEIHLFDLDDHDKLRAEIDSSVILTNATGVGMKPFEGQMLLPDDSFLRPDLIVSDVV
YNPRKTHLLEVAEKKGCRTLNGLGMMLWQGARAFEIWTGKQMPVDYIKSILF

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=282, Percent_Identity=51.063829787234, Blast_Score=318, Evalue=3e-88,
Organism=Escherichia coli, GI1789675, Length=269, Percent_Identity=29.7397769516729, Blast_Score=97, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6320332, Length=286, Percent_Identity=27.972027972028, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 32184; Mature: 32184

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFVMAERITGHTELIGLIATPIRHSMSPTMHNEAFAYLGLDYVYLAFEVGNQELKDVV
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEEEEEECCCHHHHHHH
QGFRAMKLRGFNVSMPNKTEICQYLDKLSPAAQLVGAVNTVVNDDGVLTGHITDGTGYMR
HHHHHHEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEECCHHHHH
ALSEAGIDIIGKKMTVLGAGGAATALCVQAALDGVKAISIFNRRDKFFANAEETVAKIRH
HHHHCCCEEECCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHC
NTDCEIHLFDLDDHDKLRAEIDSSVILTNATGVGMKPFEGQMLLPDDSFLRPDLIVSDVV
CCCCEEEEEECCCCHHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCCCCCCCHHHHHHH
YNPRKTHLLEVAEKKGCRTLNGLGMMLWQGARAFEIWTGKQMPVDYIKSILF
CCCCHHHHHHHHHHCCCCCHHCCHHHHHCCCCEEEEECCCCCCHHHHHHHCC
>Mature Secondary Structure
MRIFVMAERITGHTELIGLIATPIRHSMSPTMHNEAFAYLGLDYVYLAFEVGNQELKDVV
CEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCEEEEEEEECCCHHHHHHH
QGFRAMKLRGFNVSMPNKTEICQYLDKLSPAAQLVGAVNTVVNDDGVLTGHITDGTGYMR
HHHHHHEEECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEEEEECCHHHHH
ALSEAGIDIIGKKMTVLGAGGAATALCVQAALDGVKAISIFNRRDKFFANAEETVAKIRH
HHHHCCCEEECCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHC
NTDCEIHLFDLDDHDKLRAEIDSSVILTNATGVGMKPFEGQMLLPDDSFLRPDLIVSDVV
CCCCEEEEEECCCCHHHHHHCCCCEEEEECCCCCCCCCCCCEECCCCCCCCCCHHHHHHH
YNPRKTHLLEVAEKKGCRTLNGLGMMLWQGARAFEIWTGKQMPVDYIKSILF
CCCCHHHHHHHHHHCCCCCHHCCHHHHHCCCCEEEEECCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]