Definition Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome.
Accession NC_012731
Length 5,248,520

Click here to switch to the map view.

The map label for this gene is 238892925

Identifier: 238892925

GI number: 238892925

Start: 733339

End: 734559

Strand: Reverse

Name: 238892925

Synonym: KP1_0750

Alternate gene names: NA

Gene position: 734559-733339 (Counterclockwise)

Preceding gene: 238892931

Following gene: 238892920

Centisome position: 14.0

GC content: 61.92

Gene sequence:

>1221_bases
ATGAAATACCATTCAGCACCGCTCATCCCGCACAAATCCGCCCTCATGTCCGCGCCGGCTAATCTGCTGGCGGAAGAGGT
CTGTCTACCCGCCGCGCTGCTAAAAAAGTCGGCGCTGGAAAATAATATTTCATGGATGCAGCGCTACGCCGACGCCCGCG
GCGTATCGCTGGCGCCGCATGGTAAAACGACAATGACGCCATGGATATTTCAGGCGCAGCAGCGAGCGGGGGCGTGGGGG
ATCGGCGTGGGCAGCGCCTGGCAGGCTAGCGCGGCAATGGCCAGCGGCATCCAACGCGTCCTGATGGTCAATCAGCTGGT
CGGCAAAGCCAATATGCAGGTGGTCGCGCAGCTAAAAGCCCACTATCGGGCGGTGGATTTTATCTGCTGCGTCGATAGCG
AGGTCAACGTGCGCGCCCTCTCCGCATTCTTCGCAGACCAGGGACAAACGCTGGATGTGCTGATTGAACTTGGCGTGCCT
GGCGGGCGCTGCGGCTGTCGTAGCGTTGATGACGCGCTGGCGCTGGCGCAGCGGGTAAGCGACCTGCCGGGGTTACGGCT
ACGCGGACTGGAACTGTATGAAGGGGTGCTGCACGGCGACGATCCGCAGCCGCAGGTGGAAGCGCTGTTACAGCAGGCCG
CGGCGCTTGCCTGCCGCATGGAGCCGCTGGTTGACGGCGAATTTATTCTCACCGGCGCGGGCACCGTCTGGTATGACGTG
GTATGCAACATCTGGCTGGCGGCGGCAAAACCGCGCCGCTGCCGTATCGTCATCCGCCCTGGCTGTTATATCACCCACGA
TCGCGGGATCTACGATCTCGCCCAACAAGAGCTGATCGCCCGCGATCCGATTGCCTGCGATCTCGCCGGCGATCTCACTT
CAGCGCTGGAGCTGATGGCGATGGTGCAATCGGTGCCGGAGGCGGATCGCGCGGTAGTGAATTTCGGCAAGCGCGACTGC
GCTTTCGACGCCGGGCTGCCGCAACCGATCGCCCATTATCGTAATGGCCAGCAGTTAGCGCTGCGCGCGGAGTCGATCGT
CAGCACCGGCATCATGGATCAGCATTGTATGCTGCGCCTGGCGCCGGGCAGCGATGTGCAGGTCGGCGATATTCTGCTGT
TCGGCACCTCGCACCCGTGTCTGACCTTTGATAAGTGGAAGACGTTGCTGCTGGTCGATGACGACTACAACGTGCTGGAC
GAGCTCGACACGCTGTTTTGA

Upstream 100 bases:

>100_bases
TTCAAAACGAATAACATCATTATATTAAAAACATATTTATCAAATATTTATAAATGATACCCAGCGACTAACCGATTATA
AACCCTGAAAGGATAGTGTT

Downstream 100 bases:

>100_bases
CAGGCATCCGGGTAGCGGCGCTTCGCGCCTTACCCGCCCCGGCGCAAGGCGCAAATCTCATCATGCAATGAACGACTGAT
AATGACCCCCTGCCGTTCAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MKYHSAPLIPHKSALMSAPANLLAEEVCLPAALLKKSALENNISWMQRYADARGVSLAPHGKTTMTPWIFQAQQRAGAWG
IGVGSAWQASAAMASGIQRVLMVNQLVGKANMQVVAQLKAHYRAVDFICCVDSEVNVRALSAFFADQGQTLDVLIELGVP
GGRCGCRSVDDALALAQRVSDLPGLRLRGLELYEGVLHGDDPQPQVEALLQQAAALACRMEPLVDGEFILTGAGTVWYDV
VCNIWLAAAKPRRCRIVIRPGCYITHDRGIYDLAQQELIARDPIACDLAGDLTSALELMAMVQSVPEADRAVVNFGKRDC
AFDAGLPQPIAHYRNGQQLALRAESIVSTGIMDQHCMLRLAPGSDVQVGDILLFGTSHPCLTFDKWKTLLLVDDDYNVLD
ELDTLF

Sequences:

>Translated_406_residues
MKYHSAPLIPHKSALMSAPANLLAEEVCLPAALLKKSALENNISWMQRYADARGVSLAPHGKTTMTPWIFQAQQRAGAWG
IGVGSAWQASAAMASGIQRVLMVNQLVGKANMQVVAQLKAHYRAVDFICCVDSEVNVRALSAFFADQGQTLDVLIELGVP
GGRCGCRSVDDALALAQRVSDLPGLRLRGLELYEGVLHGDDPQPQVEALLQQAAALACRMEPLVDGEFILTGAGTVWYDV
VCNIWLAAAKPRRCRIVIRPGCYITHDRGIYDLAQQELIARDPIACDLAGDLTSALELMAMVQSVPEADRAVVNFGKRDC
AFDAGLPQPIAHYRNGQQLALRAESIVSTGIMDQHCMLRLAPGSDVQVGDILLFGTSHPCLTFDKWKTLLLVDDDYNVLD
ELDTLF
>Mature_406_residues
MKYHSAPLIPHKSALMSAPANLLAEEVCLPAALLKKSALENNISWMQRYADARGVSLAPHGKTTMTPWIFQAQQRAGAWG
IGVGSAWQASAAMASGIQRVLMVNQLVGKANMQVVAQLKAHYRAVDFICCVDSEVNVRALSAFFADQGQTLDVLIELGVP
GGRCGCRSVDDALALAQRVSDLPGLRLRGLELYEGVLHGDDPQPQVEALLQQAAALACRMEPLVDGEFILTGAGTVWYDV
VCNIWLAAAKPRRCRIVIRPGCYITHDRGIYDLAQQELIARDPIACDLAGDLTSALELMAMVQSVPEADRAVVNFGKRDC
AFDAGLPQPIAHYRNGQQLALRAESIVSTGIMDQHCMLRLAPGSDVQVGDILLFGTSHPCLTFDKWKTLLLVDDDYNVLD
ELDTLF

Specific function: Catalyzes the reversible cleavage of D-theronine or D- allothreonine into glycine and acetaldehyde. Can also cleave D- beta-phenylserine, D-beta-hydroxy-alpha-aminovaleric acid, D-beta- 3,4-dihydroxyphenylserine and D-beta-3,4- methylenedioxyphenylserine

COG id: COG3616

COG function: function code E; Predicted amino acid aldolase or racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DSD1 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001608 [H]

Pfam domain/function: PF01168 Ala_racemase_N [H]

EC number: =4.1.2.42 [H]

Molecular weight: Translated: 44106; Mature: 44106

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYHSAPLIPHKSALMSAPANLLAEEVCLPAALLKKSALENNISWMQRYADARGVSLAPH
CCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCC
GKTTMTPWIFQAQQRAGAWGIGVGSAWQASAAMASGIQRVLMVNQLVGKANMQVVAQLKA
CCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HYRAVDFICCVDSEVNVRALSAFFADQGQTLDVLIELGVPGGRCGCRSVDDALALAQRVS
HHHHEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
DLPGLRLRGLELYEGVLHGDDPQPQVEALLQQAAALACRMEPLVDGEFILTGAGTVWYDV
CCCCCEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHH
VCNIWLAAAKPRRCRIVIRPGCYITHDRGIYDLAQQELIARDPIACDLAGDLTSALELMA
HHHHHHHCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHH
MVQSVPEADRAVVNFGKRDCAFDAGLPQPIAHYRNGQQLALRAESIVSTGIMDQHCMLRL
HHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCEEEHHHHHHHHHCCCCCCEEEEE
APGSDVQVGDILLFGTSHPCLTFDKWKTLLLVDDDYNVLDELDTLF
CCCCCCEECEEEEEECCCCCEECCCCEEEEEEECCCHHHHHHHHCC
>Mature Secondary Structure
MKYHSAPLIPHKSALMSAPANLLAEEVCLPAALLKKSALENNISWMQRYADARGVSLAPH
CCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCC
GKTTMTPWIFQAQQRAGAWGIGVGSAWQASAAMASGIQRVLMVNQLVGKANMQVVAQLKA
CCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
HYRAVDFICCVDSEVNVRALSAFFADQGQTLDVLIELGVPGGRCGCRSVDDALALAQRVS
HHHHEEEEEEECCCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHH
DLPGLRLRGLELYEGVLHGDDPQPQVEALLQQAAALACRMEPLVDGEFILTGAGTVWYDV
CCCCCEEECHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHH
VCNIWLAAAKPRRCRIVIRPGCYITHDRGIYDLAQQELIARDPIACDLAGDLTSALELMA
HHHHHHHCCCCCEEEEEECCCEEEECCCCHHHHHHHHHHHCCCCEEECHHHHHHHHHHHH
MVQSVPEADRAVVNFGKRDCAFDAGLPQPIAHYRNGQQLALRAESIVSTGIMDQHCMLRL
HHHHCCHHHHHHHHCCCCCCCCCCCCCCHHHHHCCCCEEEHHHHHHHHHCCCCCCEEEEE
APGSDVQVGDILLFGTSHPCLTFDKWKTLLLVDDDYNVLDELDTLF
CCCCCCEECEEEEEECCCCCEECCCCEEEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9642221 [H]