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The map label for this gene is hflX [H]

Identifier: 238892657

GI number: 238892657

Start: 446532

End: 447812

Strand: Direct

Name: hflX [H]

Synonym: KP1_0442

Alternate gene names: 238892657

Gene position: 446532-447812 (Clockwise)

Preceding gene: 238892656

Following gene: 238892658

Centisome position: 8.51

GC content: 56.36

Gene sequence:

>1281_bases
TTGTTTGACCGTTATGACGCCGGTGAGCAGGCGGTACTGGTACACATCTATTTTTCGCAAGACAAAGATATGGAAGATCT
CCAGGAGTTTGAAACTCTGGCCTCTTCCGCCGGTGTCGAAGCAATGCAGGTGATTACCGGTAGCCGTAAAGCACCGCACC
CGAAGTATTTTGTTGGTGAAGGTAAGGCAGTCGAAATTGCGGAAGCCGTTAAAGCGACCGGCGCTTCGGTCGTGCTCTTC
GATCATGCCCTGAGTCCGGCGCAAGAACGTAACCTGGAACGCCTGTGCGAATGCCGGGTTATCGATCGCACCGGTCTTAT
TTTAGATATTTTCGCCCAGCGCGCGCGCACCCATGAAGGGAAATTGCAGGTCGAGCTGGCGCAGCTGCGCCATATGGCGA
CTCGCCTTGTCCGCGGTTGGACCCACCTTGAAAGACAGAAGGGCGGGATTGGTTTGCGTGGCCCGGGTGAAACCCAGCTC
GAAACCGACCGCCGTTTATTGCGTAACCGTATCATGCAGATCCTGTCGCGGCTGGAAAAAGTCGAGAAACAGCGCGAGCA
GGGGCGGCGGTCGCGTGCGAAAGCCGATATTCCTACCGTGTCGCTGGTGGGCTATACCAACGCCGGAAAATCAACGCTCT
TTAATCAGATCACTGCCGCCGAGGTCTATGCCGCGAACCAGCTGTTCGCCACCCTGGACCCGACGCTGCGCCGCATTGAC
GTCCCTGACGTCGGCGAAACGGTGCTGGCCGATACCGTGGGCTTTATTCGCCATCTGCCGCACGATCTGGTAGCCGCGTT
TAAAGCGACGTTGCAGGAGACGCGTCAGGCGACGCTGCTGCTGCATGTGATTGACGCGGCGGATGTCCGCGTGCAGGAAA
ACATTGATGCGGTAAATACGGTTCTCGCTGAAATTGAGGCCGATGAGATCCCGGCGCTGCTGGTGATGAACAAAATCGAC
ATGCTTGACGATTTTGAACCGCGCATCGATCGCGACGATGAAAATAAACCGATTCGGGTCTGGCTTTCAGCCCAGACCGG
GGTTGGCGTACCACTGCTTTTTCAGGCATTAACGGAGCGTCTTTCCGGTGAAGTGGCCCAGCATACGCTGCGCTTACCGC
CGAAAGAAGGGCGACTGAGAAGCCGTTTCTATCAGCTTCAGGCGATAGAAAAAGAGTGGATGGAGGATGACGGCAGCGTG
AGTCTGCAGGTGCGCATGCCGATCGTTGACTGGCGGCGCCTCTGTAAGCAAGAGCCAACGCTTGTTGACTATGTGGTTTA
A

Upstream 100 bases:

>100_bases
ACAAGACAGCGACGACGCCGAATAAGGCCAGTGCTGTTTTTCCACGCCGGGGAGCCAGGTTTTCTGCGTTCCCCGCTGGT
ATTTTATAAGGGGTTTACGC

Downstream 100 bases:

>100_bases
CCTTGCAGCTTGCCTGAAGATATTGACCCCTGTGGGGATATCAAAAACAAATATGGAGCATATACATGGCGTGGAATCAG
CCCGGTAATAACGGACAGGA

Product: putative GTPase HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MFDRYDAGEQAVLVHIYFSQDKDMEDLQEFETLASSAGVEAMQVITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLF
DHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHMATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRNRIMQILSRLEKVEKQREQGRRSRAKADIPTVSLVGYTNAGKSTLFNQITAAEVYAANQLFATLDPTLRRID
VPDVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIDAVNTVLAEIEADEIPALLVMNKID
MLDDFEPRIDRDDENKPIRVWLSAQTGVGVPLLFQALTERLSGEVAQHTLRLPPKEGRLRSRFYQLQAIEKEWMEDDGSV
SLQVRMPIVDWRRLCKQEPTLVDYVV

Sequences:

>Translated_426_residues
MFDRYDAGEQAVLVHIYFSQDKDMEDLQEFETLASSAGVEAMQVITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLF
DHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHMATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRNRIMQILSRLEKVEKQREQGRRSRAKADIPTVSLVGYTNAGKSTLFNQITAAEVYAANQLFATLDPTLRRID
VPDVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIDAVNTVLAEIEADEIPALLVMNKID
MLDDFEPRIDRDDENKPIRVWLSAQTGVGVPLLFQALTERLSGEVAQHTLRLPPKEGRLRSRFYQLQAIEKEWMEDDGSV
SLQVRMPIVDWRRLCKQEPTLVDYVV
>Mature_426_residues
MFDRYDAGEQAVLVHIYFSQDKDMEDLQEFETLASSAGVEAMQVITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLF
DHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEGKLQVELAQLRHMATRLVRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRNRIMQILSRLEKVEKQREQGRRSRAKADIPTVSLVGYTNAGKSTLFNQITAAEVYAANQLFATLDPTLRRID
VPDVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIDAVNTVLAEIEADEIPALLVMNKID
MLDDFEPRIDRDDENKPIRVWLSAQTGVGVPLLFQALTERLSGEVAQHTLRLPPKEGRLRSRFYQLQAIEKEWMEDDGSV
SLQVRMPIVDWRRLCKQEPTLVDYVV

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=227, Percent_Identity=33.0396475770925, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI310133116, Length=245, Percent_Identity=33.0612244897959, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI310124269, Length=227, Percent_Identity=33.4801762114537, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI310124267, Length=227, Percent_Identity=33.4801762114537, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI310124171, Length=227, Percent_Identity=33.4801762114537, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI310124169, Length=227, Percent_Identity=33.4801762114537, Blast_Score=111, Evalue=2e-24,
Organism=Escherichia coli, GI1790615, Length=426, Percent_Identity=92.2535211267606, Blast_Score=812, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17561038, Length=299, Percent_Identity=29.0969899665552, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24650079, Length=285, Percent_Identity=30.8771929824561, Blast_Score=99, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48071; Mature: 48071

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYDAGEQAVLVHIYFSQDKDMEDLQEFETLASSAGVEAMQVITGSRKAPHPKYFVGE
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEECC
GKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEG
CCEEHHHHHHHHCCCEEEEEECCCCCHHHHCHHHHHHHEEECCCCHHHHHHHHHHHCCCC
KLQVELAQLRHMATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRNRIMQILSRLEK
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VEKQREQGRRSRAKADIPTVSLVGYTNAGKSTLFNQITAAEVYAANQLFATLDPTLRRID
HHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
VPDVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIDAVNT
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHH
VLAEIEADEIPALLVMNKIDMLDDFEPRIDRDDENKPIRVWLSAQTGVGVPLLFQALTER
HHHHHCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
LSGEVAQHTLRLPPKEGRLRSRFYQLQAIEKEWMEDDGSVSLQVRMPIVDWRRLCKQEPT
HCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCC
LVDYVV
EEEECC
>Mature Secondary Structure
MFDRYDAGEQAVLVHIYFSQDKDMEDLQEFETLASSAGVEAMQVITGSRKAPHPKYFVGE
CCCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCEEECC
GKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVIDRTGLILDIFAQRARTHEG
CCEEHHHHHHHHCCCEEEEEECCCCCHHHHCHHHHHHHEEECCCCHHHHHHHHHHHCCCC
KLQVELAQLRHMATRLVRGWTHLERQKGGIGLRGPGETQLETDRRLLRNRIMQILSRLEK
CEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VEKQREQGRRSRAKADIPTVSLVGYTNAGKSTLFNQITAAEVYAANQLFATLDPTLRRID
HHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
VPDVGETVLADTVGFIRHLPHDLVAAFKATLQETRQATLLLHVIDAADVRVQENIDAVNT
CCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHH
VLAEIEADEIPALLVMNKIDMLDDFEPRIDRDDENKPIRVWLSAQTGVGVPLLFQALTER
HHHHHCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHH
LSGEVAQHTLRLPPKEGRLRSRFYQLQAIEKEWMEDDGSVSLQVRMPIVDWRRLCKQEPT
HCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCC
LVDYVV
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]