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The map label for this gene is hfq [H]

Identifier: 238892656

GI number: 238892656

Start: 446148

End: 446456

Strand: Direct

Name: hfq [H]

Synonym: KP1_0441

Alternate gene names: 238892656

Gene position: 446148-446456 (Clockwise)

Preceding gene: 238892655

Following gene: 238892657

Centisome position: 8.5

GC content: 51.78

Gene sequence:

>309_bases
ATGGCTAAGGGGCAATCTTTACAAGATCCGTTCCTGAACGCTTTGCGTCGGGAACGCGTTCCGGTTTCTATTTATTTGGT
GAATGGTATCAAGCTGCAAGGGCAAATTGAGTCTTTCGATCAGTTCGTGATCCTGTTGAAGAACACGGTCAGCCAGATGG
TCTATAAGCACGCAATTTCTACTGTTGTCCCGTCTCGCCCGGTGTCTCACCACAGCAACAATGCTGGCGGCGGTTCCAGT
AACTATCACCACGGTGGTAGCGCGCAGGGTTCTTCTGCGCCGCAACAAGACAGCGACGACGCCGAATAA

Upstream 100 bases:

>100_bases
AGAACTGAACGTGTACAATTAAACGGTATCGTGCGTAATTTTTTTTGAGAATCGTAAGGTTCTGAGTACAAAACAAGCAT
ACATATAAGGAAAAGAGAGA

Downstream 100 bases:

>100_bases
GGCCAGTGCTGTTTTTCCACGCCGGGGAGCCAGGTTTTCTGCGTTCCCCGCTGGTATTTTATAAGGGGTTTACGCTTGTT
TGACCGTTATGACGCCGGTG

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: HF-1; Host factor-I protein; HF-I [H]

Number of amino acids: Translated: 102; Mature: 101

Protein sequence:

>102_residues
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGSS
NYHHGGSAQGSSAPQQDSDDAE

Sequences:

>Translated_102_residues
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGSS
NYHHGGSAQGSSAPQQDSDDAE
>Mature_101_residues
AKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGSSN
YHHGGSAQGSSAPQQDSDDAE

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=103, Percent_Identity=92.2330097087379, Blast_Score=188, Evalue=5e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 11003; Mature: 10872

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAIS
CCCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPSRPVSHHSNNAGGGSSNYHHGGSAQGSSAPQQDSDDAE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVILLKNTVSQMVYKHAIS
CCCCCCCCHHHHHHHHCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVVPSRPVSHHSNNAGGGSSNYHHGGSAQGSSAPQQDSDDAE
HHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA