Click here to switch to the map view.

The map label for this gene is frdD [H]

Identifier: 238892638

GI number: 238892638

Start: 424597

End: 424986

Strand: Reverse

Name: frdD [H]

Synonym: KP1_0422

Alternate gene names: 238892638

Gene position: 424986-424597 (Counterclockwise)

Preceding gene: 238892639

Following gene: 238892637

Centisome position: 8.1

GC content: 57.69

Gene sequence:

>390_bases
TTGTCGCCCTGTTCTGGTAAGGAGGCTGAGATGATTAATCCCAATCCGAAACGTTCCGATGAACCCGTATTCTGGGGGCT
GTTTGGCGCAGGCGGCATGTGGGGCGCGATCGTCGCGCCGGTGATGGTGCTGCTGGTCGGCATCCTGCTGCCGCTGGGGC
TCGCTCCGGCCGACGCCTTCAGCTATGAGCGTGTGCTGGCCTTTGCCCAAAGCTTTATCGGCCGCGCATTCATCTTTCTG
ATGATTGTCCTGCCGCTGTGGTGTGGGTTGCATCGTATTCACCACGCCATGCACGATCTGAAAATCCATGTGCCAAACGG
TAAATGGGTCTTCTACGGCCTGGCGGCAATCCTCAGCGTCATCACCCTCGTTGGCGTACTGTTTATCTGA

Upstream 100 bases:

>100_bases
AAAGCCGCCAACGTCATCATCAAAGGCGAAAAAATGGGGCCAGAGCCGGTCATTAAAGGGCTCTGGGTGGTGACGGCGGT
GGTCACCGTGGTGATCCTGT

Downstream 100 bases:

>100_bases
TCCTGCAAGAGCCCGGTCGCATTTCTGCTACCGGGCTCGCTTCATAGAAAAATCTTGCCGCCTTTTCCCTGCTGGACTCT
ACACTTAGCTTAAAAGCCAG

Product: fumarate reductase subunit D

Products: fumarate; reduced acceptor

Alternate protein names: Fumarate reductase 13 kDa hydrophobic protein [H]

Number of amino acids: Translated: 129; Mature: 128

Protein sequence:

>129_residues
MSPCSGKEAEMINPNPKRSDEPVFWGLFGAGGMWGAIVAPVMVLLVGILLPLGLAPADAFSYERVLAFAQSFIGRAFIFL
MIVLPLWCGLHRIHHAMHDLKIHVPNGKWVFYGLAAILSVITLVGVLFI

Sequences:

>Translated_129_residues
MSPCSGKEAEMINPNPKRSDEPVFWGLFGAGGMWGAIVAPVMVLLVGILLPLGLAPADAFSYERVLAFAQSFIGRAFIFL
MIVLPLWCGLHRIHHAMHDLKIHVPNGKWVFYGLAAILSVITLVGVLFI
>Mature_128_residues
SPCSGKEAEMINPNPKRSDEPVFWGLFGAGGMWGAIVAPVMVLLVGILLPLGLAPADAFSYERVLAFAQSFIGRAFIFLM
IVLPLWCGLHRIHHAMHDLKIHVPNGKWVFYGLAAILSVITLVGVLFI

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane [H]

COG id: COG3080

COG function: function code C; Fumarate reductase subunit D

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdD family [H]

Homologues:

Organism=Escherichia coli, GI1790594, Length=119, Percent_Identity=87.3949579831933, Blast_Score=215, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003418
- ProDom:   PD015693 [H]

Pfam domain/function: PF02313 Fumarate_red_D [H]

EC number: 1.3.99.1

Molecular weight: Translated: 14084; Mature: 13953

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPCSGKEAEMINPNPKRSDEPVFWGLFGAGGMWGAIVAPVMVLLVGILLPLGLAPADAF
CCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
SYERVLAFAQSFIGRAFIFLMIVLPLWCGLHRIHHAMHDLKIHVPNGKWVFYGLAAILSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHH
ITLVGVLFI
HHHHHHHHC
>Mature Secondary Structure 
SPCSGKEAEMINPNPKRSDEPVFWGLFGAGGMWGAIVAPVMVLLVGILLPLGLAPADAF
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHH
SYERVLAFAQSFIGRAFIFLMIVLPLWCGLHRIHHAMHDLKIHVPNGKWVFYGLAAILSV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHHHHH
ITLVGVLFI
HHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA