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The map label for this gene is frdC

Identifier: 238892639

GI number: 238892639

Start: 424967

End: 425362

Strand: Reverse

Name: frdC

Synonym: KP1_0423

Alternate gene names: 238892639

Gene position: 425362-424967 (Counterclockwise)

Preceding gene: 238892640

Following gene: 238892638

Centisome position: 8.1

GC content: 55.81

Gene sequence:

>396_bases
ATGACGACGAAACGCAAACCCTACGTGCGACCAATGACCTCCACCTGGTGGAAAAAGCTGCCGTTTTATCGCTTCTACAT
GGTACGGGAAGGCACAGCGGTACCGACGGTATGGTTTAGCATTGTGCTGATTTATGGGCTGTTTGCCCTCAAGCACGGCG
CCGAGAGCTGGGCGGGATATATCGGATTCCTGCAAAACCCGGTGGTGGTAATCCTCAACCTGATTACTCTGGCGGCGGCG
CTGCTGCACACCAAAACCTGGTTTGAGCTGGCGCCGAAAGCCGCCAACGTCATCATCAAAGGCGAAAAAATGGGGCCAGA
GCCGGTCATTAAAGGGCTCTGGGTGGTGACGGCGGTGGTCACCGTGGTGATCCTGTTTGTCGCCCTGTTCTGGTAA

Upstream 100 bases:

>100_bases
CCGAAGCACGTCGACCCGGCGGCCGCGATCCAGCAGGGCAAGGTGGAAAGCTCGAAAGACTTTCTTATCGCCACCCTGAA
ACCACGCTAAGGAGTGCATT

Downstream 100 bases:

>100_bases
GGAGGCTGAGATGATTAATCCCAATCCGAAACGTTCCGATGAACCCGTATTCTGGGGGCTGTTTGGCGCAGGCGGCATGT
GGGGCGCGATCGTCGCGCCG

Product: fumarate reductase subunit C

Products: fumarate; reduced acceptor

Alternate protein names: Fumarate reductase 15 kDa hydrophobic protein

Number of amino acids: Translated: 131; Mature: 130

Protein sequence:

>131_residues
MTTKRKPYVRPMTSTWWKKLPFYRFYMVREGTAVPTVWFSIVLIYGLFALKHGAESWAGYIGFLQNPVVVILNLITLAAA
LLHTKTWFELAPKAANVIIKGEKMGPEPVIKGLWVVTAVVTVVILFVALFW

Sequences:

>Translated_131_residues
MTTKRKPYVRPMTSTWWKKLPFYRFYMVREGTAVPTVWFSIVLIYGLFALKHGAESWAGYIGFLQNPVVVILNLITLAAA
LLHTKTWFELAPKAANVIIKGEKMGPEPVIKGLWVVTAVVTVVILFVALFW
>Mature_130_residues
TTKRKPYVRPMTSTWWKKLPFYRFYMVREGTAVPTVWFSIVLIYGLFALKHGAESWAGYIGFLQNPVVVILNLITLAAAL
LHTKTWFELAPKAANVIIKGEKMGPEPVIKGLWVVTAVVTVVILFVALFW

Specific function: Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane

COG id: COG3029

COG function: function code C; Fumarate reductase subunit C

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the frdC family

Homologues:

Organism=Escherichia coli, GI1790595, Length=131, Percent_Identity=83.206106870229, Blast_Score=230, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FRDC_KLEP3 (B5Y348)

Other databases:

- EMBL:   CP000964
- RefSeq:   YP_002240889.1
- GeneID:   6938537
- GenomeReviews:   CP000964_GR
- KEGG:   kpe:KPK_5117
- HOGENOM:   HBG554089
- OMA:   KMGPEPV
- ProtClustDB:   PRK04987
- HAMAP:   MF_00708
- InterPro:   IPR003510
- ProDom:   PD015900

Pfam domain/function: PF02300 Fumarate_red_C

EC number: 1.3.99.1

Molecular weight: Translated: 14884; Mature: 14753

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x18faa404)-; HASH(0x18ddf9e8)-; HASH(0x19315560)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKRKPYVRPMTSTWWKKLPFYRFYMVREGTAVPTVWFSIVLIYGLFALKHGAESWAGY
CCCCCCCCCCCCHHHHHHHCCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHHH
IGFLQNPVVVILNLITLAAALLHTKTWFELAPKAANVIIKGEKMGPEPVIKGLWVVTAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCEEEECCCCCHHHHHHHHHHHHHHH
TVVILFVALFW
HHHHHHHHHHH
>Mature Secondary Structure 
TTKRKPYVRPMTSTWWKKLPFYRFYMVREGTAVPTVWFSIVLIYGLFALKHGAESWAGY
CCCCCCCCCCCHHHHHHHCCHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHCHHHHHHH
IGFLQNPVVVILNLITLAAALLHTKTWFELAPKAANVIIKGEKMGPEPVIKGLWVVTAVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCEEEECCCCCHHHHHHHHHHHHHHH
TVVILFVALFW
HHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA