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The map label for this gene is hmuV [H]

Identifier: 238028359

GI number: 238028359

Start: 3199432

End: 3201300

Strand: Reverse

Name: hmuV [H]

Synonym: bglu_1g28200

Alternate gene names: 238028359

Gene position: 3201300-3199432 (Counterclockwise)

Preceding gene: 238028360

Following gene: 238028358

Centisome position: 81.95

GC content: 77.42

Gene sequence:

>1869_bases
TTGCGCGGCGCCGCGATGACGCCCGGCCGGGCCGCGGCGATCTGGGCCGCGCTCGCGGTCGCGGCCGGGCTCGTGCTGGT
CGCGTCGCTCGCGCTCGGCAGCGTGCCGATCACGCCGTGGCAGGCGCTGTGCGCGCTGTTCGCGCCGGGCCGCGATGCGC
TCGCGGGCGAGATCGTCACCACGCTGCGCCTGCCGCGCGCACTGGCCGGCTTCGGCTGCGGCGCGCTGCTGGCGCTGGCC
GGGGCGCTGCTGCAGGTGCTGCTGCGCAATCCGCTCGCCGAGCCCTACGTGCTCGGCGTGTCGGGCGGCGCGGCCGGCTT
CGCGCTGGCGGCGATGATCGCGGGCGCCGCCTGGTGGCTCGTCGACGCGGCCTCGTTCGTCGGCGCGCTGCTGTCGACCG
CGCTGGTGCTGGGCCTGACCTATCGGCCGCTGGTGCGCGGCGCGTGGCGCGCCGGCCCGGGGGACGCGCGCGATGCGTCG
CCCAGGCTGCTGCTGACCGGCGTGGTGATCGCGGCCGGCTGGGGCGCGCTCGTCACGCTGATGCTGTCGATCGCGCCCGA
CGATCGCCTGCGCGGCATCCTGTTCTGGCTCGCGGGCGACCTCGGCAGCGCGGCGCCGCCGTGGTTCGCGCTCGGTGCGC
TGGCCTGCGCCGCGGCGGCCGCGCTGCCGGTCGCGCCACAACTGAACGTGCTGCTGCGCGGCGATACCGCGGCGGCCGCG
CTCGGCGTGCCGGTCGCGCGGCTGCGGCTGCGGATCGTGCTGATCGCCTCGCTGGCCGCCGCCCGCCGCGCTCACCGCGG
CGGGCACCATCGGTTTCGTCGGCCTGGTCGTGCGGCATGCCTTGCGGCTCGCGTTCGGCAACGACCAGCGCATGCTGCTG
CCCGCCTCGCTGCTGGCGGGCGGCGCCGTCGTGATGGGCGCCGATCTGGTGGGGCGCACCGTGATCGCGCCGGCGCAGTT
GCCGGTCGGTGCGATGACGGCGCTGCTCGGCGTACCGGTGTTCCTGTGGATGCTGCTGCGCCGGCCCGCGCCATGAGCGG
CGGGGCGAACCGCGCCGCTGGCGCCGGCGGCTGGCGCGCCTGCGGGCTGCGGCTCGCGGCCGGCTCGCGCACGCTCGTCG
AGGCCCTGTCGCTCGCGTTCGGCGCCGGCGAACTGTGGTGCATCGCCGGCCCGAACGGTGCCGGCAAGACCACCCTGATC
TCGGTGCTGGCGGGGCTCGCCGAGCCGGCCGCGGGACACGTCGAAGCCGACGGCAGACCGCTCGCCGCATGGCGGCCCGA
GTCGCTCGCGCGGCGCCGCGCGCTGATGGCGCAGACGCGCCACGACGCGTTCGCCGCGAGCGTGTTCGACACGGTGCTGG
CGCATCGCTTTCCGCATCTGGGCGGCTGGGGCTGGGAGCGCGAGGCCGATCGCGCCGCCGCGCGCGAGGCGCTGGCCAGG
CTCGATCTGGCGGCGCTCGCGCCGCGCAACGTGCTGACGCTGTCGGGCGGCGAGCGCCAGCGCGTCGCGCTGGCCGGCGT
GCTGTGCCAGGGCGCGCCGCTGCTGCTGCTCGACGAGCCGCTCGCGCACCTGGACCTGCACCATCAGGCCGATTGCCTCG
ACGCGCTCGCGCGCTGGTTGCAGGACGGTGCGCCGCGCAGCGTGATTTTCTCGTGCCACGATCTGAACCTCGCGCGCCGT
TTCGCGACCCACGCGCTGCTGCTCGACGGCCGCGGCGGCGCGCTGGCCGGCCCCGCGCGCGAGGTGCTGACGGCCGAGGC
CGCGAGCGCCGCGTTCGGCTACCCGCTGGTGCTGATCGAGCGCGACGGCCACGAGGCGCTGGTGCCGGCCTGGCCGGCGC
AGCCGCAGCGGGGGCGCACGGCGCCATGA

Upstream 100 bases:

>100_bases
CAACACGCCGCGCCGCGGCGCCTACGTCACGATCGGCTGGCGGCAGCCGTAGGGCGTCGATCATGCCGCGCGCGCCGCGC
GCCGCATGCGGGGGGCGCGG

Downstream 100 bases:

>100_bases
CGGCGGCCACGCCACCGACCCACTTACCGAGGCCGGCGCGATCCACGCGCGGGCCGCTATTCGAAACGAATCCGGCATGA
ACGATACCTACCTGGTCCCG

Product: cobalamin/Fe3+-siderophores ABC transporter ATPase

Products: ADP; phosphate; ferric enterobactin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 622; Mature: 622

Protein sequence:

>622_residues
MRGAAMTPGRAAAIWAALAVAAGLVLVASLALGSVPITPWQALCALFAPGRDALAGEIVTTLRLPRALAGFGCGALLALA
GALLQVLLRNPLAEPYVLGVSGGAAGFALAAMIAGAAWWLVDAASFVGALLSTALVLGLTYRPLVRGAWRAGPGDARDAS
PRLLLTGVVIAAGWGALVTLMLSIAPDDRLRGILFWLAGDLGSAAPPWFALGALACAAAAALPVAPQLNVLLRGDTAAAA
LGVPVARLRLRIVLIASLAAARRAHRGGHHRFRRPGRAACLAARVRQRPAHAAARLAAGGRRRRDGRRSGGAHRDRAGAV
AGRCDDGAARRTGVPVDAAAPARAMSGGANRAAGAGGWRACGLRLAAGSRTLVEALSLAFGAGELWCIAGPNGAGKTTLI
SVLAGLAEPAAGHVEADGRPLAAWRPESLARRRALMAQTRHDAFAASVFDTVLAHRFPHLGGWGWEREADRAAAREALAR
LDLAALAPRNVLTLSGGERQRVALAGVLCQGAPLLLLDEPLAHLDLHHQADCLDALARWLQDGAPRSVIFSCHDLNLARR
FATHALLLDGRGGALAGPAREVLTAEAASAAFGYPLVLIERDGHEALVPAWPAQPQRGRTAP

Sequences:

>Translated_622_residues
MRGAAMTPGRAAAIWAALAVAAGLVLVASLALGSVPITPWQALCALFAPGRDALAGEIVTTLRLPRALAGFGCGALLALA
GALLQVLLRNPLAEPYVLGVSGGAAGFALAAMIAGAAWWLVDAASFVGALLSTALVLGLTYRPLVRGAWRAGPGDARDAS
PRLLLTGVVIAAGWGALVTLMLSIAPDDRLRGILFWLAGDLGSAAPPWFALGALACAAAAALPVAPQLNVLLRGDTAAAA
LGVPVARLRLRIVLIASLAAARRAHRGGHHRFRRPGRAACLAARVRQRPAHAAARLAAGGRRRRDGRRSGGAHRDRAGAV
AGRCDDGAARRTGVPVDAAAPARAMSGGANRAAGAGGWRACGLRLAAGSRTLVEALSLAFGAGELWCIAGPNGAGKTTLI
SVLAGLAEPAAGHVEADGRPLAAWRPESLARRRALMAQTRHDAFAASVFDTVLAHRFPHLGGWGWEREADRAAAREALAR
LDLAALAPRNVLTLSGGERQRVALAGVLCQGAPLLLLDEPLAHLDLHHQADCLDALARWLQDGAPRSVIFSCHDLNLARR
FATHALLLDGRGGALAGPAREVLTAEAASAAFGYPLVLIERDGHEALVPAWPAQPQRGRTAP
>Mature_622_residues
MRGAAMTPGRAAAIWAALAVAAGLVLVASLALGSVPITPWQALCALFAPGRDALAGEIVTTLRLPRALAGFGCGALLALA
GALLQVLLRNPLAEPYVLGVSGGAAGFALAAMIAGAAWWLVDAASFVGALLSTALVLGLTYRPLVRGAWRAGPGDARDAS
PRLLLTGVVIAAGWGALVTLMLSIAPDDRLRGILFWLAGDLGSAAPPWFALGALACAAAAALPVAPQLNVLLRGDTAAAA
LGVPVARLRLRIVLIASLAAARRAHRGGHHRFRRPGRAACLAARVRQRPAHAAARLAAGGRRRRDGRRSGGAHRDRAGAV
AGRCDDGAARRTGVPVDAAAPARAMSGGANRAAGAGGWRACGLRLAAGSRTLVEALSLAFGAGELWCIAGPNGAGKTTLI
SVLAGLAEPAAGHVEADGRPLAAWRPESLARRRALMAQTRHDAFAASVFDTVLAHRFPHLGGWGWEREADRAAAREALAR
LDLAALAPRNVLTLSGGERQRVALAGVLCQGAPLLLLDEPLAHLDLHHQADCLDALARWLQDGAPRSVIFSCHDLNLARR
FATHALLLDGRGGALAGPAREVLTAEAASAAFGYPLVLIERDGHEALVPAWPAQPQRGRTAP

Specific function: Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system [H]

COG id: COG1120

COG function: function code PH; ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27881501, Length=212, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI30795238, Length=212, Percent_Identity=26.4150943396226, Blast_Score=73, Evalue=8e-13,
Organism=Homo sapiens, GI215820660, Length=200, Percent_Identity=30, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI20143975, Length=200, Percent_Identity=30, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI31657092, Length=208, Percent_Identity=27.8846153846154, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI9665248, Length=219, Percent_Identity=26.9406392694064, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1786803, Length=267, Percent_Identity=35.5805243445693, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1786345, Length=252, Percent_Identity=34.1269841269841, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1790739, Length=235, Percent_Identity=31.4893617021277, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1788002, Length=234, Percent_Identity=35.4700854700855, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87081709, Length=212, Percent_Identity=30.6603773584906, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788225, Length=212, Percent_Identity=30.6603773584906, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1786698, Length=192, Percent_Identity=29.1666666666667, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1789032, Length=212, Percent_Identity=31.6037735849057, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1788761, Length=222, Percent_Identity=31.0810810810811, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1787712, Length=185, Percent_Identity=31.8918918918919, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1789891, Length=204, Percent_Identity=32.3529411764706, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786253, Length=219, Percent_Identity=31.9634703196347, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081834, Length=204, Percent_Identity=31.8627450980392, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787029, Length=214, Percent_Identity=28.0373831775701, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786563, Length=213, Percent_Identity=30.9859154929577, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790544, Length=208, Percent_Identity=29.8076923076923, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081791, Length=180, Percent_Identity=33.3333333333333, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1787143, Length=161, Percent_Identity=29.8136645962733, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1786872, Length=193, Percent_Identity=30.0518134715026, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789873, Length=206, Percent_Identity=28.1553398058252, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787105, Length=193, Percent_Identity=30.0518134715026, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788506, Length=233, Percent_Identity=30.4721030042918, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1788004, Length=200, Percent_Identity=32.5, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786319, Length=217, Percent_Identity=26.7281105990783, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787112, Length=212, Percent_Identity=29.7169811320755, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1786653, Length=187, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788540, Length=222, Percent_Identity=30.6306306306306, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788450, Length=206, Percent_Identity=28.1553398058252, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786703, Length=200, Percent_Identity=30.5, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789751, Length=206, Percent_Identity=30.0970873786408, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI115533592, Length=224, Percent_Identity=29.9107142857143, Blast_Score=76, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR015863
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 63965; Mature: 63965

Theoretical pI: Translated: 11.80; Mature: 11.80

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGAAMTPGRAAAIWAALAVAAGLVLVASLALGSVPITPWQALCALFAPGRDALAGEIVT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHH
TLRLPRALAGFGCGALLALAGALLQVLLRNPLAEPYVLGVSGGAAGFALAAMIAGAAWWL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
VDAASFVGALLSTALVLGLTYRPLVRGAWRAGPGDARDASPRLLLTGVVIAAGWGALVTL
HHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
MLSIAPDDRLRGILFWLAGDLGSAAPPWFALGALACAAAAALPVAPQLNVLLRGDTAAAA
HHHCCCCHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHH
LGVPVARLRLRIVLIASLAAARRAHRGGHHRFRRPGRAACLAARVRQRPAHAAARLAAGG
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCC
RRRRDGRRSGGAHRDRAGAVAGRCDDGAARRTGVPVDAAAPARAMSGGANRAAGAGGWRA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHH
CGLRLAAGSRTLVEALSLAFGAGELWCIAGPNGAGKTTLISVLAGLAEPAAGHVEADGRP
HCEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
LAAWRPESLARRRALMAQTRHDAFAASVFDTVLAHRFPHLGGWGWEREADRAAAREALAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LDLAALAPRNVLTLSGGERQRVALAGVLCQGAPLLLLDEPLAHLDLHHQADCLDALARWL
HHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEEEECCCHHHHCCHHHHHHHHHHHHHH
QDGAPRSVIFSCHDLNLARRFATHALLLDGRGGALAGPAREVLTAEAASAAFGYPLVLIE
HCCCCCEEEEEEHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEE
RDGHEALVPAWPAQPQRGRTAP
CCCCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MRGAAMTPGRAAAIWAALAVAAGLVLVASLALGSVPITPWQALCALFAPGRDALAGEIVT
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHH
TLRLPRALAGFGCGALLALAGALLQVLLRNPLAEPYVLGVSGGAAGFALAAMIAGAAWWL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
VDAASFVGALLSTALVLGLTYRPLVRGAWRAGPGDARDASPRLLLTGVVIAAGWGALVTL
HHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
MLSIAPDDRLRGILFWLAGDLGSAAPPWFALGALACAAAAALPVAPQLNVLLRGDTAAAA
HHHCCCCHHHHHHHEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHH
LGVPVARLRLRIVLIASLAAARRAHRGGHHRFRRPGRAACLAARVRQRPAHAAARLAAGG
HCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHCHHHHHHHHHCCC
RRRRDGRRSGGAHRDRAGAVAGRCDDGAARRTGVPVDAAAPARAMSGGANRAAGAGGWRA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHH
CGLRLAAGSRTLVEALSLAFGAGELWCIAGPNGAGKTTLISVLAGLAEPAAGHVEADGRP
HCEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCC
LAAWRPESLARRRALMAQTRHDAFAASVFDTVLAHRFPHLGGWGWEREADRAAAREALAR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
LDLAALAPRNVLTLSGGERQRVALAGVLCQGAPLLLLDEPLAHLDLHHQADCLDALARWL
HHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEEEECCCHHHHCCHHHHHHHHHHHHHH
QDGAPRSVIFSCHDLNLARRFATHALLLDGRGGALAGPAREVLTAEAASAAFGYPLVLIE
HCCCCCEEEEEEHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEEE
RDGHEALVPAWPAQPQRGRTAP
CCCCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; ferric enterobactin [Periplasm]; H2O [C]

Specific reaction: ATP + ferric enterobactin [Periplasm] + H2O = ADP + phosphate + ferric enterobactin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA