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The map label for this gene is hisQ [H]

Identifier: 238028317

GI number: 238028317

Start: 3147392

End: 3148081

Strand: Direct

Name: hisQ [H]

Synonym: bglu_1g27780

Alternate gene names: 238028317

Gene position: 3147392-3148081 (Clockwise)

Preceding gene: 238028316

Following gene: 238028318

Centisome position: 80.57

GC content: 64.06

Gene sequence:

>690_bases
ATGTTTCTTCAAGGCTACGGCCCGCTGATACTTTCCGGCACCTGGCAGACCATCAAGCTCGCCGTGCTGTCGCTCGCCTT
CGCGTTCGTGCTCGGCCTGCTCGGCGCGGCCGCGAAACTCTCGCGCAACCGGATCACGAACGGGCTCGGCACGCTCTACA
CCACGCTGATCCGCGGCGTGCCCGATCTGGTGCTGATGCTGCTGCTGTTCTACAGCCTGCAGATCTGGCTCAACCAATTC
ACCGACATGATGAACTGGGATCAGATCGACATCGACCCGTTCGCGGCCGGCGTGCTGGTGCTCGGCTTCATCTACGGCGC
CTACTTCACCGAAACCTTCCGCGGCGCGTTCCTGTCGGTGCCGCGCGGCCAGCTCGAGGCGGGCGCCGCCTACGGGATGT
CGAACTGGCGGGTGTTCTCGCGCGTGATGTTCCCGCAGATGATGCGCTTCGCGCTGCCCGGCATCGGCAACAACTGGCAG
GTGCTCGTCAAGTCCACCGCGCTGGTGTCGATCATCGGCCTGGCCGACGTGGTCAAGGCCTCGCAGGACGCCGGCAAGGG
CACGCTGCGTTTCTTCTTCTTCACGCTGCTCGCGGGGGCCATCTACCTCGCGATCACGACGATCTCGAACTTCGTGCTGA
TGTGGCTGGAAAAGCGCTACTCCACGGGCGTCCGCAAGGCTGACCTATGA

Upstream 100 bases:

>100_bases
CGGAATCACCGGGCAGCCCGACCCACATGCACGGGGCGTGCCGCCCGACCCGCGGCACGCGTCTTTCTCGGCGCCCGCGT
TGCGCCGTCAAGGACTTCAT

Downstream 100 bases:

>100_bases
TCGAACTGATTCAGGAATACTGGCGCAACTACCTCTACACCGACGGCTATCACATCACCGGCGTGGCGATCACCCTGTGG
CTGCTGGTGGTGTCGATCGG

Product: amino acid ABC transporter permease

Products: ADP; phosphate; L-histidine [Cytoplasm]; ADP; L-ornithine [Cytoplasm]; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MFLQGYGPLILSGTWQTIKLAVLSLAFAFVLGLLGAAAKLSRNRITNGLGTLYTTLIRGVPDLVLMLLLFYSLQIWLNQF
TDMMNWDQIDIDPFAAGVLVLGFIYGAYFTETFRGAFLSVPRGQLEAGAAYGMSNWRVFSRVMFPQMMRFALPGIGNNWQ
VLVKSTALVSIIGLADVVKASQDAGKGTLRFFFFTLLAGAIYLAITTISNFVLMWLEKRYSTGVRKADL

Sequences:

>Translated_229_residues
MFLQGYGPLILSGTWQTIKLAVLSLAFAFVLGLLGAAAKLSRNRITNGLGTLYTTLIRGVPDLVLMLLLFYSLQIWLNQF
TDMMNWDQIDIDPFAAGVLVLGFIYGAYFTETFRGAFLSVPRGQLEAGAAYGMSNWRVFSRVMFPQMMRFALPGIGNNWQ
VLVKSTALVSIIGLADVVKASQDAGKGTLRFFFFTLLAGAIYLAITTISNFVLMWLEKRYSTGVRKADL
>Mature_229_residues
MFLQGYGPLILSGTWQTIKLAVLSLAFAFVLGLLGAAAKLSRNRITNGLGTLYTTLIRGVPDLVLMLLLFYSLQIWLNQF
TDMMNWDQIDIDPFAAGVLVLGFIYGAYFTETFRGAFLSVPRGQLEAGAAYGMSNWRVFSRVMFPQMMRFALPGIGNNWQ
VLVKSTALVSIIGLADVVKASQDAGKGTLRFFFFTLLAGAIYLAITTISNFVLMWLEKRYSTGVRKADL

Specific function: Part of the binding-protein-dependent transport system for histidine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4215

COG function: function code E; ABC-type arginine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788646, Length=227, Percent_Identity=60.352422907489, Blast_Score=283, Evalue=7e-78,
Organism=Escherichia coli, GI1787087, Length=225, Percent_Identity=34.2222222222222, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1787030, Length=212, Percent_Identity=33.4905660377358, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI1788226, Length=221, Percent_Identity=28.9592760180996, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788645, Length=217, Percent_Identity=30.4147465437788, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1786874, Length=181, Percent_Identity=32.5966850828729, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082239, Length=214, Percent_Identity=27.1028037383178, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1786873, Length=212, Percent_Identity=25, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1787086, Length=217, Percent_Identity=26.2672811059908, Blast_Score=64, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25354; Mature: 25354

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLQGYGPLILSGTWQTIKLAVLSLAFAFVLGLLGAAAKLSRNRITNGLGTLYTTLIRGV
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDLVLMLLLFYSLQIWLNQFTDMMNWDQIDIDPFAAGVLVLGFIYGAYFTETFRGAFLSV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRGQLEAGAAYGMSNWRVFSRVMFPQMMRFALPGIGNNWQVLVKSTALVSIIGLADVVKA
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SQDAGKGTLRFFFFTLLAGAIYLAITTISNFVLMWLEKRYSTGVRKADL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFLQGYGPLILSGTWQTIKLAVLSLAFAFVLGLLGAAAKLSRNRITNGLGTLYTTLIRGV
CCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PDLVLMLLLFYSLQIWLNQFTDMMNWDQIDIDPFAAGVLVLGFIYGAYFTETFRGAFLSV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRGQLEAGAAYGMSNWRVFSRVMFPQMMRFALPGIGNNWQVLVKSTALVSIIGLADVVKA
CCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SQDAGKGTLRFFFFTLLAGAIYLAITTISNFVLMWLEKRYSTGVRKADL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O; ATP; L-ornithine [Periplasm]; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [P

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]