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The map label for this gene is arnA [H]

Identifier: 238027029

GI number: 238027029

Start: 1548857

End: 1549912

Strand: Reverse

Name: arnA [H]

Synonym: bglu_1g14070

Alternate gene names: 238027029

Gene position: 1549912-1548857 (Counterclockwise)

Preceding gene: 238027030

Following gene: 238027028

Centisome position: 39.68

GC content: 61.55

Gene sequence:

>1056_bases
ATGAAAGCAAAAAAAGTCCTGATCCTGGGTGTGAACGGCTTCATCGGCCATCACCTGTCCAAACGCATTCTTGAAACCAC
CGATTGGGAAGTATTCGGGATGGACATGCAGACCGACCGGCTTGGCGACCTCGTCAACCACCCGCGGATGCATTTCTTCG
AAGGCGACATCACGATCAACAAGGAATGGGTGGAATACCACGTCAAGAAGTGCGACGTGATCCTGCCGCTGGTCGCGATC
GCCACGCCCGCCACCTATGTGCAGCAGCCGCTGCGCGTGTTCGAGCTCGATTTCGAGGCGAACCTGCCGATCGTGCGTTC
GGCCGTGAAATACGGCAAGCATCTGGTGTTTCCGTCGACTTCCGAGGTCTACGGCATGTGCTCGGACGAGCAGTTCGATC
CGGACGCTTCCGCGCTCACCTATGGCCCGATCAACAAGCCGCGCTGGATCTACGCCTGCTCGAAGCAGTTGATGGATCGC
GTGATCTGGGGCTACGGCATGGAGGGCCTGAACTTCACGCTGTTCCGCCCGTTCAACTGGATCGGCCCGGGCCTCGACTC
GATCTACACGCCCAAGGAAGGCAGCTCGCGCGTGGTCACGCAGTTCCTCGGCCACATCGTGCGCGGCGAGAACATCAGCC
TCGTCGACGGCGGCTCGCAGAAGCGCGCGTTCACCTATGTCGACGACGGCATCAGCGCGCTGATGAAGATCATCGAGAAC
CGCGACGGCGTGGCCACCGGCAAGATCTACAACATCGGCAACCCGAGCAACAACTACTCGGTGCGCGAGCTCGCGCACAA
GATGCTCGAACTGGCGGCCGAATTCCCCGAGTACGCCGATTCGGCGAAGAACGTGCAGCTCGTCGAGACCACCTCGGGCG
CCTACTACGGCAACGGCTACCAGGACGTGCAGAACCGCGTGCCGAAGATCGACAATACGATGCAAGAGCTCGGCTGGGCA
CCGGAGACGACGTTCGACGACGCGCTGCGCAACATCTTCGAGGCGTACCGCGGCCACGTGGCCGACGCGCGCGCGCTGGT
CGAGCAGCAAGGCTGA

Upstream 100 bases:

>100_bases
CCGTCCTCGAGTTGCGCGAAGCGCGCAACGGCGGCCCGGATTCCGGCCCGGTCGTCTCTCCCGCTCAATTCGCGCAGTTC
ATTGATTCTTCCCGCCAGTC

Downstream 100 bases:

>100_bases
CGCGTTGGCCCGCATCGTCCTCAAGATCGACGTCGACACGCTGCGCGGCACGCGCGAGGGTGTGCCGAACCTCGCGCGGA
TCTTCGATCGCTACGCCGCG

Product: NAD-dependent epimerase/dehydratase family protein

Products: NA

Alternate protein names: UDP-4-amino-4-deoxy-L-arabinose formyltransferase; ArnAFT; UDP-L-Ara4N formyltransferase; UDP-glucuronic acid oxidase, UDP-4-keto-hexauronic acid decarboxylating; ArnADH; UDP-GlcUA decarboxylase; UDP-glucuronic acid dehydrogenase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MKAKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVNHPRMHFFEGDITINKEWVEYHVKKCDVILPLVAI
ATPATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDR
VIWGYGMEGLNFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTYVDDGISALMKIIEN
RDGVATGKIYNIGNPSNNYSVRELAHKMLELAAEFPEYADSAKNVQLVETTSGAYYGNGYQDVQNRVPKIDNTMQELGWA
PETTFDDALRNIFEAYRGHVADARALVEQQG

Sequences:

>Translated_351_residues
MKAKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVNHPRMHFFEGDITINKEWVEYHVKKCDVILPLVAI
ATPATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDR
VIWGYGMEGLNFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTYVDDGISALMKIIEN
RDGVATGKIYNIGNPSNNYSVRELAHKMLELAAEFPEYADSAKNVQLVETTSGAYYGNGYQDVQNRVPKIDNTMQELGWA
PETTFDDALRNIFEAYRGHVADARALVEQQG
>Mature_351_residues
MKAKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVNHPRMHFFEGDITINKEWVEYHVKKCDVILPLVAI
ATPATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPSTSEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDR
VIWGYGMEGLNFTLFRPFNWIGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTYVDDGISALMKIIEN
RDGVATGKIYNIGNPSNNYSVRELAHKMLELAAEFPEYADSAKNVQLVETTSGAYYGNGYQDVQNRVPKIDNTMQELGWA
PETTFDDALRNIFEAYRGHVADARALVEQQG

Specific function: Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabin

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the sugar epimerase family. UDP-glucuronic acid decarboxylase subfamily [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=337, Percent_Identity=26.1127596439169, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI7657641, Length=349, Percent_Identity=23.4957020057307, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1788589, Length=339, Percent_Identity=55.1622418879056, Blast_Score=381, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17539532, Length=344, Percent_Identity=24.4186046511628, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356223, Length=346, Percent_Identity=23.4104046242775, Blast_Score=82, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021168
- InterPro:   IPR001509
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase; PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.13; =1.1.1.305 [H]

Molecular weight: Translated: 39546; Mature: 39546

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVNHPRMHFFEGDITIN
CCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCEEEEECCEEEC
KEWVEYHVKKCDVILPLVAIATPATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPST
HHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHEEEECCCCCCHHHHHHHHHCCEEECCCC
SEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDRVIWGYGMEGLNFTLFRPFNW
HHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
IGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTYVDDGISALMKIIEN
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHC
RDGVATGKIYNIGNPSNNYSVRELAHKMLELAAEFPEYADSAKNVQLVETTSGAYYGNGY
CCCCEECEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCCCEEEEEECCCCCCCCCH
QDVQNRVPKIDNTMQELGWAPETTFDDALRNIFEAYRGHVADARALVEQQG
HHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCC
>Mature Secondary Structure
MKAKKVLILGVNGFIGHHLSKRILETTDWEVFGMDMQTDRLGDLVNHPRMHFFEGDITIN
CCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHCCCCEEEEECCEEEC
KEWVEYHVKKCDVILPLVAIATPATYVQQPLRVFELDFEANLPIVRSAVKYGKHLVFPST
HHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHEEEECCCCCCHHHHHHHHHCCEEECCCC
SEVYGMCSDEQFDPDASALTYGPINKPRWIYACSKQLMDRVIWGYGMEGLNFTLFRPFNW
HHHHCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCC
IGPGLDSIYTPKEGSSRVVTQFLGHIVRGENISLVDGGSQKRAFTYVDDGISALMKIIEN
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHC
RDGVATGKIYNIGNPSNNYSVRELAHKMLELAAEFPEYADSAKNVQLVETTSGAYYGNGY
CCCCEECEEEECCCCCCCCHHHHHHHHHHHHHHHCHHHHCCCCCEEEEEECCCCCCCCCH
QDVQNRVPKIDNTMQELGWAPETTFDDALRNIFEAYRGHVADARALVEQQG
HHHHHCCCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA