Click here to switch to the map view.

The map label for this gene is alkK [H]

Identifier: 238026992

GI number: 238026992

Start: 1510143

End: 1511840

Strand: Direct

Name: alkK [H]

Synonym: bglu_1g13700

Alternate gene names: 238026992

Gene position: 1510143-1511840 (Clockwise)

Preceding gene: 238026986

Following gene: 238026993

Centisome position: 38.66

GC content: 69.79

Gene sequence:

>1698_bases
ATGAGCATCACGATGAACCCGCCTTTGCTGGGCCAGATGATGGAGGTGCCGCTGCTGGTGTCGTCGCTGATCACGCATGC
GGCGCGGCATGCCGGCGGCGTGGAGATCGTGTCGCGCCGGATCGAAGGCGATCTGCACCGCTACACCTATCGCGACTGCG
AACGGCGCGCCAAGCAGCTCGCGCAGGCGCTCACGCGGGCCGGCGTCGCGCCGGGCGAGCGCGTCGGCACGCTGGCCTGG
AACGGCTACCGCCACCTGGAGGCGTATTTCGGCATCGCCGGGATGGGCGCCGTCAGCCATACGATCAACCCGCGCCTGTT
TCTCGAGCAACTCGTCTATATCGTCAACCATGCCGACGATCGTTTCATCCTGTTCGATCTCAACTTCGCGCCGCTGATCG
ACCAGCTCGCGCCGCAGTGCCCGAACGTGCGCGGCTGGATCGCGCTGACCGACGCGGCGCACCTGCCCGCGGCGGCCACG
CCGCTGATCGCGTATGAAACGCTGCTCGACGCGGAGGATGGCGATTACGACTGGCCGCGCCTCGACGAGCGCCAGGCCTC
GTCGCTCTGCTACACGTCGGGCACCACCGGCCATCCGAAGGGCGCGCTCTACTCGCACCGCTCGACGGTGCTGCACGCCT
ACGCGGCCGCACTGCCCGACGCGATGGCGCTGTCGATGCTCGACGCGGTGCTGCCGGTGGTGCCGATGTTCCACGTCAAC
GCCTGGGGCCTGCCCTACGCGGTGCCGCTCACCGGCGCGAAGCTGGTGCTGCCCGGCAAGGATCTGGACGGCAAGTCGGT
CTACGAGCTGATGGAAGCGGAGCGCGTGACCTGCTCGGCCGGCGTGCCGACCGTCTGGCTCGGCCTGCTCAACTACATGC
GCGAGGCCGGGGTGCGCTTCTCGACGCTCCGACGCACCGTGATCGGCGGCTCCGCATGCCCGCCCAGCATGCTGCGCGCG
TTCGAGGACGATTACGGCGTGCAGGTGATCCACGCCTGGGGCATGACCGAGCTGTCGCCGCTCGGCACGCTGGCGCGGCC
GACCTGGGCGCAGATGCAGCGGCCCGAGGCCGAGCGGCGCCAGTCGCTCGAAAAACAGGGCCGCGTGGTCTGCGGCATCG
ACATGCGCATCGTCGGCGAGGACGGCAGCGAGCTGCCCTGGGACGGCGTCGCGTTCGGCGAGCTGCAGGTGCGCGGGCCG
TGGGTGATCGACGGCTATTTCCAGGGCGAGGGCTCGCCGCTCGTCGACGGCTGGTTCCCGACCGGCGACGTCGCCACCAT
CGATCGCGACGGCTTCCTGCAGATCACCGATCGCAGCAAGGACGTGATCAAGTCGGGCGGCGAATGGATCAGCTCGATCG
ACCTGGAGAACATCGCCGTCGCGCACCCGGGCGTGGCCGAGGCGGCCTGCATCGCCTGCGCGCATCCGAAATGGACGGAA
CGGCCGCTGCTCGTGGTGGTGCGCCGGCCCGGCAGCGACCTGACGCGCGAGGCGCTGCTCGCGTTCTACGAGGGCAAGGT
CGCGAAATGGTGGATACCCGACGACGTGGTGTTCGTCGAGGCGCTGCCGCACACGGCCACCGGCAAGCTGCAAAAGCTCA
GGCTGCGCGAGATGTTCCGCGAGCACGTGCTGCCCACCGCCGTCGCCGGCGATAGCCCGCGCGAAAGCGTGCCGGCGCGA
TCGGCCGGGCGGGGCTGA

Upstream 100 bases:

>100_bases
GCACAAGCCGATATTGTAAATCCGCGCCGCGCGGGCCGCTTGCGGCCGCGGACCCGACCACGATCGGGGCTCGAGACAAT
CCAACCGGGAGAGCTGGACG

Downstream 100 bases:

>100_bases
GGGCTGAGGGCCGTGGGCCGTCGCGCCGGGCCGCCGCGATCGGCGGAGGGCCGGGTTGCGTCGGGGCCGGGCGGCGGCCG
TGTCGGGCCTCGTCGAGTGT

Product: long-chain-fatty-acid--CoA ligase

Products: NA

Alternate protein names: Medium-chain acyl-CoA synthetase [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MSITMNPPLLGQMMEVPLLVSSLITHAARHAGGVEIVSRRIEGDLHRYTYRDCERRAKQLAQALTRAGVAPGERVGTLAW
NGYRHLEAYFGIAGMGAVSHTINPRLFLEQLVYIVNHADDRFILFDLNFAPLIDQLAPQCPNVRGWIALTDAAHLPAAAT
PLIAYETLLDAEDGDYDWPRLDERQASSLCYTSGTTGHPKGALYSHRSTVLHAYAAALPDAMALSMLDAVLPVVPMFHVN
AWGLPYAVPLTGAKLVLPGKDLDGKSVYELMEAERVTCSAGVPTVWLGLLNYMREAGVRFSTLRRTVIGGSACPPSMLRA
FEDDYGVQVIHAWGMTELSPLGTLARPTWAQMQRPEAERRQSLEKQGRVVCGIDMRIVGEDGSELPWDGVAFGELQVRGP
WVIDGYFQGEGSPLVDGWFPTGDVATIDRDGFLQITDRSKDVIKSGGEWISSIDLENIAVAHPGVAEAACIACAHPKWTE
RPLLVVVRRPGSDLTREALLAFYEGKVAKWWIPDDVVFVEALPHTATGKLQKLRLREMFREHVLPTAVAGDSPRESVPAR
SAGRG

Sequences:

>Translated_565_residues
MSITMNPPLLGQMMEVPLLVSSLITHAARHAGGVEIVSRRIEGDLHRYTYRDCERRAKQLAQALTRAGVAPGERVGTLAW
NGYRHLEAYFGIAGMGAVSHTINPRLFLEQLVYIVNHADDRFILFDLNFAPLIDQLAPQCPNVRGWIALTDAAHLPAAAT
PLIAYETLLDAEDGDYDWPRLDERQASSLCYTSGTTGHPKGALYSHRSTVLHAYAAALPDAMALSMLDAVLPVVPMFHVN
AWGLPYAVPLTGAKLVLPGKDLDGKSVYELMEAERVTCSAGVPTVWLGLLNYMREAGVRFSTLRRTVIGGSACPPSMLRA
FEDDYGVQVIHAWGMTELSPLGTLARPTWAQMQRPEAERRQSLEKQGRVVCGIDMRIVGEDGSELPWDGVAFGELQVRGP
WVIDGYFQGEGSPLVDGWFPTGDVATIDRDGFLQITDRSKDVIKSGGEWISSIDLENIAVAHPGVAEAACIACAHPKWTE
RPLLVVVRRPGSDLTREALLAFYEGKVAKWWIPDDVVFVEALPHTATGKLQKLRLREMFREHVLPTAVAGDSPRESVPAR
SAGRG
>Mature_564_residues
SITMNPPLLGQMMEVPLLVSSLITHAARHAGGVEIVSRRIEGDLHRYTYRDCERRAKQLAQALTRAGVAPGERVGTLAWN
GYRHLEAYFGIAGMGAVSHTINPRLFLEQLVYIVNHADDRFILFDLNFAPLIDQLAPQCPNVRGWIALTDAAHLPAAATP
LIAYETLLDAEDGDYDWPRLDERQASSLCYTSGTTGHPKGALYSHRSTVLHAYAAALPDAMALSMLDAVLPVVPMFHVNA
WGLPYAVPLTGAKLVLPGKDLDGKSVYELMEAERVTCSAGVPTVWLGLLNYMREAGVRFSTLRRTVIGGSACPPSMLRAF
EDDYGVQVIHAWGMTELSPLGTLARPTWAQMQRPEAERRQSLEKQGRVVCGIDMRIVGEDGSELPWDGVAFGELQVRGPW
VIDGYFQGEGSPLVDGWFPTGDVATIDRDGFLQITDRSKDVIKSGGEWISSIDLENIAVAHPGVAEAACIACAHPKWTER
PLLVVVRRPGSDLTREALLAFYEGKVAKWWIPDDVVFVEALPHTATGKLQKLRLREMFREHVLPTAVAGDSPRESVPARS
AGRG

Specific function: Unknown

COG id: COG0318

COG function: function code IQ; Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family [H]

Homologues:

Organism=Homo sapiens, GI156151445, Length=527, Percent_Identity=28.4629981024668, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI187761345, Length=530, Percent_Identity=27.3584905660377, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI187761343, Length=530, Percent_Identity=27.3584905660377, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI38505220, Length=504, Percent_Identity=23.4126984126984, Blast_Score=106, Evalue=7e-23,
Organism=Homo sapiens, GI28416953, Length=576, Percent_Identity=25.3472222222222, Blast_Score=102, Evalue=9e-22,
Organism=Homo sapiens, GI122937307, Length=510, Percent_Identity=21.3725490196078, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI115511026, Length=512, Percent_Identity=20.5078125, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI58082049, Length=512, Percent_Identity=21.875, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI157311624, Length=511, Percent_Identity=21.7221135029354, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI157311622, Length=511, Percent_Identity=21.7221135029354, Blast_Score=85, Evalue=2e-16,
Organism=Homo sapiens, GI42544132, Length=454, Percent_Identity=21.5859030837004, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI145693145, Length=520, Percent_Identity=26.9230769230769, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI221142682, Length=515, Percent_Identity=24.8543689320388, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788107, Length=532, Percent_Identity=27.2556390977444, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1789201, Length=537, Percent_Identity=25.1396648044693, Blast_Score=123, Evalue=3e-29,
Organism=Escherichia coli, GI1786810, Length=539, Percent_Identity=25.2319109461967, Blast_Score=116, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71994703, Length=534, Percent_Identity=25.2808988764045, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71994694, Length=534, Percent_Identity=25.2808988764045, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI71994690, Length=534, Percent_Identity=25.2808988764045, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17531443, Length=538, Percent_Identity=23.6059479553903, Blast_Score=137, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17558820, Length=520, Percent_Identity=25.3846153846154, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI32563687, Length=514, Percent_Identity=27.431906614786, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17560308, Length=535, Percent_Identity=25.0467289719626, Blast_Score=129, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17557194, Length=540, Percent_Identity=23.5185185185185, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17538037, Length=532, Percent_Identity=22.5563909774436, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17559526, Length=364, Percent_Identity=27.1978021978022, Blast_Score=119, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71996755, Length=355, Percent_Identity=22.8169014084507, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71985884, Length=383, Percent_Identity=23.2375979112272, Blast_Score=80, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319699, Length=360, Percent_Identity=28.8888888888889, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24581924, Length=567, Percent_Identity=25.7495590828924, Blast_Score=155, Evalue=5e-38,
Organism=Drosophila melanogaster, GI18859661, Length=365, Percent_Identity=28.7671232876712, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21355181, Length=495, Percent_Identity=23.4343434343434, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI19922652, Length=501, Percent_Identity=21.1576846307385, Blast_Score=84, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24648260, Length=375, Percent_Identity=25.6, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI21356441, Length=373, Percent_Identity=23.5924932975871, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648257, Length=483, Percent_Identity=22.7743271221532, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648253, Length=367, Percent_Identity=21.5258855585831, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20130357, Length=366, Percent_Identity=22.4043715846995, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24648255, Length=381, Percent_Identity=21.259842519685, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24656500, Length=504, Percent_Identity=23.015873015873, Blast_Score=74, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281365686, Length=250, Percent_Identity=22.4, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24653035, Length=518, Percent_Identity=20.2702702702703, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020845
- InterPro:   IPR000873 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: NA

Molecular weight: Translated: 61926; Mature: 61794

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSITMNPPLLGQMMEVPLLVSSLITHAARHAGGVEIVSRRIEGDLHRYTYRDCERRAKQL
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHH
AQALTRAGVAPGERVGTLAWNGYRHLEAYFGIAGMGAVSHTINPRLFLEQLVYIVNHADD
HHHHHHCCCCCCCCEEEEEECCHHHHHHHHCHHCCCHHHHCCCHHHHHHHHHHHHHCCCC
RFILFDLNFAPLIDQLAPQCPNVRGWIALTDAAHLPAAATPLIAYETLLDAEDGDYDWPR
EEEEEECCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
LDERQASSLCYTSGTTGHPKGALYSHRSTVLHAYAAALPDAMALSMLDAVLPVVPMFHVN
CCHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
AWGLPYAVPLTGAKLVLPGKDLDGKSVYELMEAERVTCSAGVPTVWLGLLNYMREAGVRF
CCCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHCEECCCCHHHHHHHHHHHHHCCCHH
STLRRTVIGGSACPPSMLRAFEDDYGVQVIHAWGMTELSPLGTLARPTWAQMQRPEAERR
HHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCHHHHH
QSLEKQGRVVCGIDMRIVGEDGSELPWDGVAFGELQVRGPWVIDGYFQGEGSPLVDGWFP
HHHHHCCCEEEEEEEEEECCCCCCCCCCCEEECEEEECCCEEEEEEEECCCCEEECCCCC
TGDVATIDRDGFLQITDRSKDVIKSGGEWISSIDLENIAVAHPGVAEAACIACAHPKWTE
CCCEEEECCCCCEEEECCCHHHHHCCCHHHHHCCCCCEEECCCCHHHHHHHEECCCCCCC
RPLLVVVRRPGSDLTREALLAFYEGKVAKWWIPDDVVFVEALPHTATGKLQKLRLREMFR
CCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHH
EHVLPTAVAGDSPRESVPARSAGRG
HHCCCEEECCCCCHHCCCCCCCCCC
>Mature Secondary Structure 
SITMNPPLLGQMMEVPLLVSSLITHAARHAGGVEIVSRRIEGDLHRYTYRDCERRAKQL
EEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCHHHHHHHHHHHHHHHHH
AQALTRAGVAPGERVGTLAWNGYRHLEAYFGIAGMGAVSHTINPRLFLEQLVYIVNHADD
HHHHHHCCCCCCCCEEEEEECCHHHHHHHHCHHCCCHHHHCCCHHHHHHHHHHHHHCCCC
RFILFDLNFAPLIDQLAPQCPNVRGWIALTDAAHLPAAATPLIAYETLLDAEDGDYDWPR
EEEEEECCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCCCC
LDERQASSLCYTSGTTGHPKGALYSHRSTVLHAYAAALPDAMALSMLDAVLPVVPMFHVN
CCHHHHCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCC
AWGLPYAVPLTGAKLVLPGKDLDGKSVYELMEAERVTCSAGVPTVWLGLLNYMREAGVRF
CCCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHCEECCCCHHHHHHHHHHHHHCCCHH
STLRRTVIGGSACPPSMLRAFEDDYGVQVIHAWGMTELSPLGTLARPTWAQMQRPEAERR
HHHHHHHHCCCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCHHHHH
QSLEKQGRVVCGIDMRIVGEDGSELPWDGVAFGELQVRGPWVIDGYFQGEGSPLVDGWFP
HHHHHCCCEEEEEEEEEECCCCCCCCCCCEEECEEEECCCEEEEEEEECCCCEEECCCCC
TGDVATIDRDGFLQITDRSKDVIKSGGEWISSIDLENIAVAHPGVAEAACIACAHPKWTE
CCCEEEECCCCCEEEECCCHHHHHCCCHHHHHCCCCCEEECCCCHHHHHHHEECCCCCCC
RPLLVVVRRPGSDLTREALLAFYEGKVAKWWIPDDVVFVEALPHTATGKLQKLRLREMFR
CCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHH
EHVLPTAVAGDSPRESVPARSAGRG
HHCCCEEECCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1453953 [H]