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The map label for this gene is hisQ [H]

Identifier: 238026653

GI number: 238026653

Start: 1084857

End: 1085546

Strand: Direct

Name: hisQ [H]

Synonym: bglu_1g10060

Alternate gene names: 238026653

Gene position: 1084857-1085546 (Clockwise)

Preceding gene: 238026652

Following gene: 238026654

Centisome position: 27.77

GC content: 66.52

Gene sequence:

>690_bases
GTGTTCCTATACGGATTCGGCCCCCTCATCTGGGCGGGCACCGTGCAGACCATCGAGCTGTCGGTGCTCTCGCTCGCCGC
GGCGGTCGCGCTCGGCCTGGCCGGCGCGGTCGCGAAGCTGTCGACTCACCGCGTGCTGCGCGCGCTCGCCACGGCCTACA
CCACGCTGATCCGCTCGGTGCCGGACCTGGTGCTGATGCTGCTGCTGTTCTACAGCATCCAGATCTGGCTGAACCAGATC
ACCGACCTGCTCGGCTGGGACCAGATCGACATCGACCCGTTCGTGGCCGGCGTGCTGACGCTCGGCTTCATCTACGGCGC
CTACTTCACCGAGACGTTTCGCGGCGCGTTCCTGTCGGTGCCGCGCGGCCAGCTCGAGGCGGGCGCGGCCTACGGCATGA
GCGGGATGCGCGTGTTTACGCGCATCCTGTTCCCGCAGATGATGCGCTTCGCGCTGCCCGGCATCGGCAACAACTGGCAG
GTGCTCGTGAAGGCCACGGCGCTGGTCTCCATCATTGGCCTCGCCGACGTCGTGAAGGCCGCGCAGGACGCGGGCAAGAG
CACCTTCAAGATGTTTTTCTTCATCCTCGTCGCGGCGCTGGTCTATCTGGCGATCACGACGCTTTCCAACCTGGTGCTGC
GGCAGCTGGAGCGGCGCTACTCGCTCGGCGTGAGGCACGCGGAACTATGA

Upstream 100 bases:

>100_bases
GAGCCGGTTTTTTTCGCGAGCCACCATCCGCCGCATCCCCTGGCCGCTTCCCGAGAAGAAGCCGCCGCCCCGACCCGCCA
CCGTCCACCCGGAGACACGC

Downstream 100 bases:

>100_bases
TCGAGATCCTGCAGGAATTCGGCCGTGCGTTCCTCTACCACGACGGCCAGCGTTTCTCGGGCCTCGTGGTCACGCTGTGG
CTGCTGGCGGCGTCGATCGG

Product: histidine ABC transporter permease HisQ

Products: ADP; phosphate; L-histidine [Cytoplasm]; ADP; L-ornithine [Cytoplasm]; L-arginine [Cytoplasm]; L-lysine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MFLYGFGPLIWAGTVQTIELSVLSLAAAVALGLAGAVAKLSTHRVLRALATAYTTLIRSVPDLVLMLLLFYSIQIWLNQI
TDLLGWDQIDIDPFVAGVLTLGFIYGAYFTETFRGAFLSVPRGQLEAGAAYGMSGMRVFTRILFPQMMRFALPGIGNNWQ
VLVKATALVSIIGLADVVKAAQDAGKSTFKMFFFILVAALVYLAITTLSNLVLRQLERRYSLGVRHAEL

Sequences:

>Translated_229_residues
MFLYGFGPLIWAGTVQTIELSVLSLAAAVALGLAGAVAKLSTHRVLRALATAYTTLIRSVPDLVLMLLLFYSIQIWLNQI
TDLLGWDQIDIDPFVAGVLTLGFIYGAYFTETFRGAFLSVPRGQLEAGAAYGMSGMRVFTRILFPQMMRFALPGIGNNWQ
VLVKATALVSIIGLADVVKAAQDAGKSTFKMFFFILVAALVYLAITTLSNLVLRQLERRYSLGVRHAEL
>Mature_229_residues
MFLYGFGPLIWAGTVQTIELSVLSLAAAVALGLAGAVAKLSTHRVLRALATAYTTLIRSVPDLVLMLLLFYSIQIWLNQI
TDLLGWDQIDIDPFVAGVLTLGFIYGAYFTETFRGAFLSVPRGQLEAGAAYGMSGMRVFTRILFPQMMRFALPGIGNNWQ
VLVKATALVSIIGLADVVKAAQDAGKSTFKMFFFILVAALVYLAITTLSNLVLRQLERRYSLGVRHAEL

Specific function: Part of the binding-protein-dependent transport system for histidine; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4215

COG function: function code E; ABC-type arginine transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788646, Length=227, Percent_Identity=60.352422907489, Blast_Score=276, Evalue=6e-76,
Organism=Escherichia coli, GI1787087, Length=216, Percent_Identity=34.7222222222222, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1787030, Length=215, Percent_Identity=30.6976744186047, Blast_Score=109, Evalue=1e-25,
Organism=Escherichia coli, GI1788226, Length=218, Percent_Identity=29.8165137614679, Blast_Score=91, Evalue=5e-20,
Organism=Escherichia coli, GI1788645, Length=224, Percent_Identity=29.9107142857143, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1786873, Length=212, Percent_Identity=29.7169811320755, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786874, Length=225, Percent_Identity=29.7777777777778, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082239, Length=220, Percent_Identity=26.8181818181818, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787086, Length=219, Percent_Identity=27.3972602739726, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 25043; Mature: 25043

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLYGFGPLIWAGTVQTIELSVLSLAAAVALGLAGAVAKLSTHRVLRALATAYTTLIRSV
CCEECCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PDLVLMLLLFYSIQIWLNQITDLLGWDQIDIDPFVAGVLTLGFIYGAYFTETFRGAFLSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRGQLEAGAAYGMSGMRVFTRILFPQMMRFALPGIGNNWQVLVKATALVSIIGLADVVKA
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AQDAGKSTFKMFFFILVAALVYLAITTLSNLVLRQLERRYSLGVRHAEL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MFLYGFGPLIWAGTVQTIELSVLSLAAAVALGLAGAVAKLSTHRVLRALATAYTTLIRSV
CCEECCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PDLVLMLLLFYSIQIWLNQITDLLGWDQIDIDPFVAGVLTLGFIYGAYFTETFRGAFLSV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PRGQLEAGAAYGMSGMRVFTRILFPQMMRFALPGIGNNWQVLVKATALVSIIGLADVVKA
CCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AQDAGKSTFKMFFFILVAALVYLAITTLSNLVLRQLERRYSLGVRHAEL
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-histidine [Periplasm]; H2O; ATP; L-ornithine [Periplasm]; L-arginine [Periplasm]; L-lysine [Periplasm] [C]

Specific reaction: ATP + L-histidine [Periplasm] + H2O = ADP + phosphate + L-histidine [Cytoplasm] ATP + L-ornithine [Periplasm] + H2O = ADP + phosphate + L-ornithine [Cytoplasm] ATP + L-arginine [Periplasm] + H2O = ADP + phosphate + L-arginine [Cytoplasm] ATP + L-lysine [P

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]