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The map label for this gene is tcp [H]

Identifier: 238025381

GI number: 238025381

Start: 2553542

End: 2555179

Strand: Reverse

Name: tcp [H]

Synonym: bglu_2g20620

Alternate gene names: 238025381

Gene position: 2555179-2553542 (Counterclockwise)

Preceding gene: 238025382

Following gene: 238025378

Centisome position: 90.37

GC content: 63.06

Gene sequence:

>1638_bases
ATGAACATCTCGAATATGAAGGTTAAGTTCAAGCTGACTTTCTCCTTCGGTATACTAATCATTCTCGTTCTGGCGGTGTC
GGGCTTCGCACTTAGCTCGCTCAACGCGGCAAACGCCAGATTCGAGGGGTTTGTAAAAGGTGTCAACGCTCGCGCCAAAC
TGGCCGAGCAGATCCGAACCTCCGTCGACCGCCGCGCGATCGCCGCGCGGGACATTCTGTTCGTCACCTCGCCAGCCGAA
ATCGAGTCGGAGAAGGTCAAGGCGATGAAGGCCCACGAGGAAGTTCACGAGAAGCTGACGCAACTGCAACAGATGCTGGC
CGGCGCCTCGGACTCCAGCGAGAAAGCGAAGGAACTGGTCGCGAACATCGCGAGCGTCGAAGAAAAGTACGGGCCGGTTG
CGCTTGCGATCGTTCAGGCTGGCACCGGAAACCGCCGTGACGAGGCCGTGAAGATGATTGACGAGCAGTGCCGTCCGCTT
CTTACCGCGCTGATCAGCGCCACCAATGCCTACGGCGAATACACCCAGTCGCACGCGGAGGAAATGATCAAGCAGGCATC
GGAGAATTTCTCCCTGCAACGCACGCTGCTCATCATGATCAGTCTTGCGTCCGGCTTGGCGGCCGTGGTCGCCGGCGTGT
TGATCACGAGGAGCCTGACCCGGGCGCTGGGCGCCGAACCCGCACAGCTGGGCGCGATTACACGTCGGGTTGCCGACGGC
GATCTGCGGCCGGTGGAGGACGCCGCGCATGCGCCGAAGGGGAGTGTCCTCGCCTCGCTCGGAGAAATGCAAGGCAGCCT
GGTCAAGCTGGTCGGCCAGATCCGAGCCTCGGCCGACAACATCGCCACCGGCGCGAGCGAGATTGCGTCGGGCAATCAGG
ATCTCTCCTCGCGTACCGAACAGCAGGCGTCGTCGCTCCAGGAAACTGCCTCGAGCATGGAGGAACTGACGTCGACCGTG
AAGCAGAACGCTGAAAATGCGCAGCAGGCCAGCGGACTGGCCGCCAACGCGTCGGAGGTGGCGCATAAGGGCAGCGCGGT
GGTCGGACAGGTCGTCGGCACCATGACCGAGATCAGCCAGAGTTCGACGAAGGTCGCCGATATCACCGGCATTATCGAAA
GCATCGCGTTCCAGACCAATATTCTCGCACTGAACGCAGCGGTGGAAGCGGCGCGCGCCGGCGAACAGGGGCGCGGCTTC
GCCGTGGTGGCGAGCGAAGTCCGCAATCTCGCGCAGCGCTCGTCCAGCGCGGCCAAGGAGATCAAGGACCTGATCGGCGC
GTCGGTGCAGAAAATTCAGGACGGTGCCGCATTGGCCGGCGAGGCTGGCAAGACGATGTCGGAAGTCACGCAAGCCGTTG
CCCGCGTGACGGACATCATGGGGGAAATTGCAGCGGCATCGGGCGAGCAGAGCCGGGGAATCGAACAGGTGAACCTGGCT
ATCACGCAGATGGATCAGGTCACGCAGCAGAATGCGGCACTGGTGGAGGAAGCGGCGGCAGCCTCGCAGTCGCTCGAGGG
GCAGGGACGCCAGCTGACGCAGGCGATCGCGTTCTTCCGCGTCAGTGACACCATGTCGGCCACGCCGACATGGAGGGATT
CGGACGGGCTGCGCCGGGCGGCTTTGCCGCGTCCCTGA

Upstream 100 bases:

>100_bases
GAGATTCTTTATTCAAGCAACTCGCGTGTCTTCCGTAGTAACGGTTAAGGCATGCAAGACATGACTGGGTGTAGAAAAGG
ACCAACAAAAAGGAAATCGT

Downstream 100 bases:

>100_bases
TCCAAGGCCGTTTTTCCGACACCTCGTCGGCGAGTCGGAGCCCGGGCCGGGGCCGAGGCCGATAACCGGCACGCTTGCTG
AGCCACCGCCGGCTACTTAC

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 545; Mature: 545

Protein sequence:

>545_residues
MNISNMKVKFKLTFSFGILIILVLAVSGFALSSLNAANARFEGFVKGVNARAKLAEQIRTSVDRRAIAARDILFVTSPAE
IESEKVKAMKAHEEVHEKLTQLQQMLAGASDSSEKAKELVANIASVEEKYGPVALAIVQAGTGNRRDEAVKMIDEQCRPL
LTALISATNAYGEYTQSHAEEMIKQASENFSLQRTLLIMISLASGLAAVVAGVLITRSLTRALGAEPAQLGAITRRVADG
DLRPVEDAAHAPKGSVLASLGEMQGSLVKLVGQIRASADNIATGASEIASGNQDLSSRTEQQASSLQETASSMEELTSTV
KQNAENAQQASGLAANASEVAHKGSAVVGQVVGTMTEISQSSTKVADITGIIESIAFQTNILALNAAVEAARAGEQGRGF
AVVASEVRNLAQRSSSAAKEIKDLIGASVQKIQDGAALAGEAGKTMSEVTQAVARVTDIMGEIAAASGEQSRGIEQVNLA
ITQMDQVTQQNAALVEEAAAASQSLEGQGRQLTQAIAFFRVSDTMSATPTWRDSDGLRRAALPRP

Sequences:

>Translated_545_residues
MNISNMKVKFKLTFSFGILIILVLAVSGFALSSLNAANARFEGFVKGVNARAKLAEQIRTSVDRRAIAARDILFVTSPAE
IESEKVKAMKAHEEVHEKLTQLQQMLAGASDSSEKAKELVANIASVEEKYGPVALAIVQAGTGNRRDEAVKMIDEQCRPL
LTALISATNAYGEYTQSHAEEMIKQASENFSLQRTLLIMISLASGLAAVVAGVLITRSLTRALGAEPAQLGAITRRVADG
DLRPVEDAAHAPKGSVLASLGEMQGSLVKLVGQIRASADNIATGASEIASGNQDLSSRTEQQASSLQETASSMEELTSTV
KQNAENAQQASGLAANASEVAHKGSAVVGQVVGTMTEISQSSTKVADITGIIESIAFQTNILALNAAVEAARAGEQGRGF
AVVASEVRNLAQRSSSAAKEIKDLIGASVQKIQDGAALAGEAGKTMSEVTQAVARVTDIMGEIAAASGEQSRGIEQVNLA
ITQMDQVTQQNAALVEEAAAASQSLEGQGRQLTQAIAFFRVSDTMSATPTWRDSDGLRRAALPRP
>Mature_545_residues
MNISNMKVKFKLTFSFGILIILVLAVSGFALSSLNAANARFEGFVKGVNARAKLAEQIRTSVDRRAIAARDILFVTSPAE
IESEKVKAMKAHEEVHEKLTQLQQMLAGASDSSEKAKELVANIASVEEKYGPVALAIVQAGTGNRRDEAVKMIDEQCRPL
LTALISATNAYGEYTQSHAEEMIKQASENFSLQRTLLIMISLASGLAAVVAGVLITRSLTRALGAEPAQLGAITRRVADG
DLRPVEDAAHAPKGSVLASLGEMQGSLVKLVGQIRASADNIATGASEIASGNQDLSSRTEQQASSLQETASSMEELTSTV
KQNAENAQQASGLAANASEVAHKGSAVVGQVVGTMTEISQSSTKVADITGIIESIAFQTNILALNAAVEAARAGEQGRGF
AVVASEVRNLAQRSSSAAKEIKDLIGASVQKIQDGAALAGEAGKTMSEVTQAVARVTDIMGEIAAASGEQSRGIEQVNLA
ITQMDQVTQQNAALVEEAAAASQSLEGQGRQLTQAIAFFRVSDTMSATPTWRDSDGLRRAALPRP

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=334, Percent_Identity=58.3832335329341, Blast_Score=320, Evalue=2e-88,
Organism=Escherichia coli, GI1788195, Length=305, Percent_Identity=58.0327868852459, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1787690, Length=378, Percent_Identity=51.3227513227513, Blast_Score=298, Evalue=8e-82,
Organism=Escherichia coli, GI1788194, Length=343, Percent_Identity=51.3119533527697, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI1789453, Length=286, Percent_Identity=37.4125874125874, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57143; Mature: 57143

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNISNMKVKFKLTFSFGILIILVLAVSGFALSSLNAANARFEGFVKGVNARAKLAEQIRT
CCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHH
SVDRRAIAARDILFVTSPAEIESEKVKAMKAHEEVHEKLTQLQQMLAGASDSSEKAKELV
HHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ANIASVEEKYGPVALAIVQAGTGNRRDEAVKMIDEQCRPLLTALISATNAYGEYTQSHAE
HHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMIKQASENFSLQRTLLIMISLASGLAAVVAGVLITRSLTRALGAEPAQLGAITRRVADG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
DLRPVEDAAHAPKGSVLASLGEMQGSLVKLVGQIRASADNIATGASEIASGNQDLSSRTE
CCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHH
QQASSLQETASSMEELTSTVKQNAENAQQASGLAANASEVAHKGSAVVGQVVGTMTEISQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHH
SSTKVADITGIIESIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSSSAAKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IKDLIGASVQKIQDGAALAGEAGKTMSEVTQAVARVTDIMGEIAAASGEQSRGIEQVNLA
HHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHH
ITQMDQVTQQNAALVEEAAAASQSLEGQGRQLTQAIAFFRVSDTMSATPTWRDSDGLRRA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ALPRP
CCCCC
>Mature Secondary Structure
MNISNMKVKFKLTFSFGILIILVLAVSGFALSSLNAANARFEGFVKGVNARAKLAEQIRT
CCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHH
SVDRRAIAARDILFVTSPAEIESEKVKAMKAHEEVHEKLTQLQQMLAGASDSSEKAKELV
HHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
ANIASVEEKYGPVALAIVQAGTGNRRDEAVKMIDEQCRPLLTALISATNAYGEYTQSHAE
HHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMIKQASENFSLQRTLLIMISLASGLAAVVAGVLITRSLTRALGAEPAQLGAITRRVADG
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
DLRPVEDAAHAPKGSVLASLGEMQGSLVKLVGQIRASADNIATGASEIASGNQDLSSRTE
CCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHH
QQASSLQETASSMEELTSTVKQNAENAQQASGLAANASEVAHKGSAVVGQVVGTMTEISQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCHHHHHHHHHHHHHHHH
SSTKVADITGIIESIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRNLAQRSSSAAKE
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IKDLIGASVQKIQDGAALAGEAGKTMSEVTQAVARVTDIMGEIAAASGEQSRGIEQVNLA
HHHHHHHHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHH
ITQMDQVTQQNAALVEEAAAASQSLEGQGRQLTQAIAFFRVSDTMSATPTWRDSDGLRRA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ALPRP
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]