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The map label for this gene is luxQ [H]

Identifier: 238025378

GI number: 238025378

Start: 2546174

End: 2547841

Strand: Reverse

Name: luxQ [H]

Synonym: bglu_2g20560

Alternate gene names: 238025378

Gene position: 2547841-2546174 (Counterclockwise)

Preceding gene: 238025381

Following gene: 238025377

Centisome position: 90.11

GC content: 69.12

Gene sequence:

>1668_bases
ATGGCCCTGGACGCGCTGCAAATACTTAATACATTTCCGGAAGAAGCCTACGACCGCATCGTGCGGCGCGTCAGCCAATT
CTTCTCGGTGCCCATCTGCGTGATCTCGTTCATGGATCACGACGCTCAATGGTTCAAGGCGAAAGTCGGCGTGGAGATTC
AATCGACGCCGCGCGAATGGTCGTTCTCCCAGGCCGCGCTCGAAACGGACGGCGTGTTCGCCGTGGAGGACACGCACCAC
TGCGCGCGTTTCGCTCAGCATCCGGCAGTGCGCGGCGAGCCGGGCATCCGCTTCTATGCGGGCATAGCGCTCGCGATAGA
GCGTGACCAGAGGATCGGGGTGCTGTGCCTGGTGGACACGCGCCCGCGTGCGTTTGACAGCGCGGCGCGCGAAGCGTTGA
AGGATTTCGCGGCGATCGCCGTGGACGAGCTGCATTTGCGCTTGCGCACGCGCCGTCTCGAGACGGAACTGGCCGCGCGG
CGGGAAGCCGAGGCGGCCGCGTTGCAGGCGCAGAAGGAGCGCGCCGATTTTCTCGCGATGGTCACGCACGAAGTGCGCAC
GCCGCTTGCCGCGGTGGCGGGCATCGCCTCGCTGATGTGCCACGGCGGCGAGCTGCCTAATGCGCTCAGTGCGACGGCAC
TGCTGGAGTCGACCGAACATCTGGCGCGCCTGCTCAACGAGGTGCTCGATCTGGCGCGCATCGAGGCCAACGGCTTCACG
TTCCGCCGCGAGCCCTTCGATCTGCTCCGGGAGCTGCGTTGCGCGCTCGACGTCTTTAGGCCGCAAGCCGCGGCCAAGGG
CGTGGAGTTGCGGCTGCACGTCGATCCCGCCATGCCGCCGGCGGTTCTCGGCGATCGCACGCGCGTCGCGCAGATCATGC
TGAACCTGTTGTCGAATGCCCTGAAATTCACCGAGCGCGGCCAGATCGAGGTGACGGCCGCCGTTCATCCGGGGCGCGAC
GCAGGCGCCGAAATCGCCATCGAGGTTCGCGACACCGGGATCGGCATGGAGCCGGCCGCCGCGCGCGCGCTGTTTTCCAG
GTTCCGCCAGGCCGCCCCGGCGATTCGCTCCAGCTATGGCGGCACCGGGCTCGGCCTCGCCATTTGCCAGCGATTGATTC
ACGGCATGGGCGGAACCATCGGCGTCGAGAGCGAGCCGGGGGCCGGTACGCGGGTCCGCCTCCGCTTGCCGTGCGCGATC
GCCCCCCGCGTCGAGGCCGCCGCCGCGCAAGCGCCGGCGGCGCGGGCCGCGATGCGGCGCGGCGACTATCTGGTGCTGGT
GGCGGACGACGACACGGTCGGCAGGAAGATCGTGAGCGCGATGCTGAGCCGCCTCGGCTACCGCGTGGAAGCGTTCGCCA
GCGGCCGCGCGGCACTGGCCGCGCTGCGCGAGCGGCCGTTCGACGTGGCGATCGTGGACCTGCAGATGCCCGATCTCGAC
GGCGTCTCGCTGGCCCGCGAGCTGCACACGCAGTCGGAGTTCGGCGCGACGGTGCCGCTGATCGCGCTGACGGGGCAGCC
GAGGCCCGACGACGCGCTCGTCGAGCGCCTGTTCAACGGCTATCTCGTCAAGCCCGCCAGCGCCGCGGCATTGGACGAGG
CGATCACGGAGATCCTGTCGCGGCGTGACTGCGCGACGCCCTGCACGCTCGCGGAGCGGGTCGCATGA

Upstream 100 bases:

>100_bases
ATCAGTGATCGGGGATCGGACAACGCTCGTCTGCGACGGGCAAGCCAACAGTCCTGGTACGGCGAATGCCGACGTGCGCG
CGCGGGAATCGAAGCGCCTC

Downstream 100 bases:

>100_bases
CGATCCCGACCAATCCGGCTGCGGGGCCCGCCGCGGCGCGGCCCTACCGGCGCCGCATCGGCTGGCTCGGCACCACGGCG
CTAGCCGTGGGCGGCAGCAA

Product: GAF sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MALDALQILNTFPEEAYDRIVRRVSQFFSVPICVISFMDHDAQWFKAKVGVEIQSTPREWSFSQAALETDGVFAVEDTHH
CARFAQHPAVRGEPGIRFYAGIALAIERDQRIGVLCLVDTRPRAFDSAAREALKDFAAIAVDELHLRLRTRRLETELAAR
REAEAAALQAQKERADFLAMVTHEVRTPLAAVAGIASLMCHGGELPNALSATALLESTEHLARLLNEVLDLARIEANGFT
FRREPFDLLRELRCALDVFRPQAAAKGVELRLHVDPAMPPAVLGDRTRVAQIMLNLLSNALKFTERGQIEVTAAVHPGRD
AGAEIAIEVRDTGIGMEPAAARALFSRFRQAAPAIRSSYGGTGLGLAICQRLIHGMGGTIGVESEPGAGTRVRLRLPCAI
APRVEAAAAQAPAARAAMRRGDYLVLVADDDTVGRKIVSAMLSRLGYRVEAFASGRAALAALRERPFDVAIVDLQMPDLD
GVSLARELHTQSEFGATVPLIALTGQPRPDDALVERLFNGYLVKPASAAALDEAITEILSRRDCATPCTLAERVA

Sequences:

>Translated_555_residues
MALDALQILNTFPEEAYDRIVRRVSQFFSVPICVISFMDHDAQWFKAKVGVEIQSTPREWSFSQAALETDGVFAVEDTHH
CARFAQHPAVRGEPGIRFYAGIALAIERDQRIGVLCLVDTRPRAFDSAAREALKDFAAIAVDELHLRLRTRRLETELAAR
REAEAAALQAQKERADFLAMVTHEVRTPLAAVAGIASLMCHGGELPNALSATALLESTEHLARLLNEVLDLARIEANGFT
FRREPFDLLRELRCALDVFRPQAAAKGVELRLHVDPAMPPAVLGDRTRVAQIMLNLLSNALKFTERGQIEVTAAVHPGRD
AGAEIAIEVRDTGIGMEPAAARALFSRFRQAAPAIRSSYGGTGLGLAICQRLIHGMGGTIGVESEPGAGTRVRLRLPCAI
APRVEAAAAQAPAARAAMRRGDYLVLVADDDTVGRKIVSAMLSRLGYRVEAFASGRAALAALRERPFDVAIVDLQMPDLD
GVSLARELHTQSEFGATVPLIALTGQPRPDDALVERLFNGYLVKPASAAALDEAITEILSRRDCATPCTLAERVA
>Mature_554_residues
ALDALQILNTFPEEAYDRIVRRVSQFFSVPICVISFMDHDAQWFKAKVGVEIQSTPREWSFSQAALETDGVFAVEDTHHC
ARFAQHPAVRGEPGIRFYAGIALAIERDQRIGVLCLVDTRPRAFDSAAREALKDFAAIAVDELHLRLRTRRLETELAARR
EAEAAALQAQKERADFLAMVTHEVRTPLAAVAGIASLMCHGGELPNALSATALLESTEHLARLLNEVLDLARIEANGFTF
RREPFDLLRELRCALDVFRPQAAAKGVELRLHVDPAMPPAVLGDRTRVAQIMLNLLSNALKFTERGQIEVTAAVHPGRDA
GAEIAIEVRDTGIGMEPAAARALFSRFRQAAPAIRSSYGGTGLGLAICQRLIHGMGGTIGVESEPGAGTRVRLRLPCAIA
PRVEAAAAQAPAARAAMRRGDYLVLVADDDTVGRKIVSAMLSRLGYRVEAFASGRAALAALRERPFDVAIVDLQMPDLDG
VSLARELHTQSEFGATVPLIALTGQPRPDDALVERLFNGYLVKPASAAALDEAITEILSRRDCATPCTLAERVA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=405, Percent_Identity=32.5925925925926, Blast_Score=175, Evalue=8e-45,
Organism=Escherichia coli, GI48994928, Length=411, Percent_Identity=28.7104622871046, Blast_Score=165, Evalue=8e-42,
Organism=Escherichia coli, GI1788713, Length=365, Percent_Identity=29.5890410958904, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1789149, Length=272, Percent_Identity=33.0882352941176, Blast_Score=158, Evalue=9e-40,
Organism=Escherichia coli, GI145693157, Length=250, Percent_Identity=34.8, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1786912, Length=255, Percent_Identity=29.4117647058824, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1788393, Length=231, Percent_Identity=28.1385281385281, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=28.6821705426357, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786783, Length=229, Percent_Identity=27.9475982532751, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788549, Length=252, Percent_Identity=26.1904761904762, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=29.6137339055794, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082128, Length=236, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=88, Percent_Identity=38.6363636363636, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60207; Mature: 60076

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDALQILNTFPEEAYDRIVRRVSQFFSVPICVISFMDHDAQWFKAKVGVEIQSTPREW
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHCCEEEECCCCCC
SFSQAALETDGVFAVEDTHHCARFAQHPAVRGEPGIRFYAGIALAIERDQRIGVLCLVDT
CCHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCEEEEEEECC
RPRAFDSAAREALKDFAAIAVDELHLRLRTRRLETELAARREAEAAALQAQKERADFLAM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTHEVRTPLAAVAGIASLMCHGGELPNALSATALLESTEHLARLLNEVLDLARIEANGFT
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
FRREPFDLLRELRCALDVFRPQAAAKGVELRLHVDPAMPPAVLGDRTRVAQIMLNLLSNA
EECCHHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHH
LKFTERGQIEVTAAVHPGRDAGAEIAIEVRDTGIGMEPAAARALFSRFRQAAPAIRSSYG
HHHCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GTGLGLAICQRLIHGMGGTIGVESEPGAGTRVRLRLPCAIAPRVEAAAAQAPAARAAMRR
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEECCCHHHHHHCCHHHHHHHHC
GDYLVLVADDDTVGRKIVSAMLSRLGYRVEAFASGRAALAALRERPFDVAIVDLQMPDLD
CCEEEEEECCCHHHHHHHHHHHHHHCCEEEHHHCCHHHHHHHHHCCCEEEEEEEECCCCC
GVSLARELHTQSEFGATVPLIALTGQPRPDDALVERLFNGYLVKPASAAALDEAITEILS
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCEEECCCHHHHHHHHHHHHHH
RRDCATPCTLAERVA
CCCCCCCHHHHHHCC
>Mature Secondary Structure 
ALDALQILNTFPEEAYDRIVRRVSQFFSVPICVISFMDHDAQWFKAKVGVEIQSTPREW
CCHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHCCEEEECCCCCC
SFSQAALETDGVFAVEDTHHCARFAQHPAVRGEPGIRFYAGIALAIERDQRIGVLCLVDT
CCHHHHHCCCCEEEECCCHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCEEEEEEECC
RPRAFDSAAREALKDFAAIAVDELHLRLRTRRLETELAARREAEAAALQAQKERADFLAM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VTHEVRTPLAAVAGIASLMCHGGELPNALSATALLESTEHLARLLNEVLDLARIEANGFT
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
FRREPFDLLRELRCALDVFRPQAAAKGVELRLHVDPAMPPAVLGDRTRVAQIMLNLLSNA
EECCHHHHHHHHHHHHHHHCCHHHCCCEEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHH
LKFTERGQIEVTAAVHPGRDAGAEIAIEVRDTGIGMEPAAARALFSRFRQAAPAIRSSYG
HHHCCCCCEEEEEEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GTGLGLAICQRLIHGMGGTIGVESEPGAGTRVRLRLPCAIAPRVEAAAAQAPAARAAMRR
CCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCEECCCHHHHHHCCHHHHHHHHC
GDYLVLVADDDTVGRKIVSAMLSRLGYRVEAFASGRAALAALRERPFDVAIVDLQMPDLD
CCEEEEEECCCHHHHHHHHHHHHHHCCEEEHHHCCHHHHHHHHHCCCEEEEEEEECCCCC
GVSLARELHTQSEFGATVPLIALTGQPRPDDALVERLFNGYLVKPASAAALDEAITEILS
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHCCEEECCCHHHHHHHHHHHHHH
RRDCATPCTLAERVA
CCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA