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The map label for this gene is bla [H]

Identifier: 238024897

GI number: 238024897

Start: 1949836

End: 1950732

Strand: Reverse

Name: bla [H]

Synonym: bglu_2g15400

Alternate gene names: 238024897

Gene position: 1950732-1949836 (Counterclockwise)

Preceding gene: 238024898

Following gene: 238024893

Centisome position: 69.0

GC content: 74.8

Gene sequence:

>897_bases
ATGCTGCCATCGCATTCCCCGCGCCCCTGGCCGGCGCGCGCGGGTCTGCCCCGTGTCGACACGGCCCGCGCGCTCGCCGC
GCTGACGCTGCTTGCCGCGGCGCTGGCGAGCCCGCCCGCCGGCGCCGACACGCGCACGCTCTGCACGATCGTGGCCGACG
CGGCCTCGGGCCGGGTGCTCGCCGAACGCGGCGAGGGGTGCGCCACGCGCGTCACGCCCGCCTCGACCTTCAAGATCGCC
CTGAGCCTGATGGGCTTCGATGCCGGCGTGCTGACGGACGCGCACGCGCCCGTGCTGCCGTTTCGTGCCGGCTACCCCGA
CTGGGGCGGCGACGCGTGGCGCCAGCCGACCGATCCGGCGCGCTGGATGCGCTATTCGGTGTTCTGGTATTCGCAGCAGC
TCACGCAGCGCCTCGGCCAGGCGCGCTTCGCGAGCTACACGCAGCGCTTCGGCTACGGCAACGCGGACGTGGCGCCCGGC
CCAGGCGAGTTCGCCGGCATGAAGGGCGCCTGGAACTCGGGATCGCTGCGCATCGCGCCGCGCGAGCAGATCGCGTTTCT
GCGCGCGATCGTGAACCGCACGCTGCCGGTGAGCGCGCATGCGTTCGAGATGACCGACCGGATCACGCTGATCGACGCGC
AGCCGGACGGCTGGATCGTGCACGGCAAGACCGGCACCAGCTCGCCGGGCGACGACGGCCGCTTCGATCGCGCGCGGGCC
TATGGCTGGTTCGTCGGCTGGGCGGCGCGCGGCACGCGCGCCGTGGTGTTCGCGCACCTGATTCAGGACGACGCGCCGCA
CGACGTGAGCGCCGGCCTGCGCGCGCGCGACGCGCTGCTGGCCGAACTGCCGGCGCTGGCGCTGCCGGCTGCCGGGGCGG
TGCCGCCCGCGCGTTGA

Upstream 100 bases:

>100_bases
CTGAACGGCGCCGGCTGCCGCGCTTTCCGGTTGCCGGCTCGCCGCGACGGGCTGCCGGCTGCCTGCCTCCCCGCCACGAT
ACCAACCAGAGAGAATCTTG

Downstream 100 bases:

>100_bases
GCGCCGTCGCCTGCCTCGACGGCAGGCGCCGCGCCCTCGAACCGCCGGCGCGCGCAACGCGGCGTGCCGCGGCGGCGGGG
GCCGATCGATCGCGCGACGG

Product: beta-lactamase

Products: NA

Alternate protein names: Oxacillinase; Penicillinase [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MLPSHSPRPWPARAGLPRVDTARALAALTLLAAALASPPAGADTRTLCTIVADAASGRVLAERGEGCATRVTPASTFKIA
LSLMGFDAGVLTDAHAPVLPFRAGYPDWGGDAWRQPTDPARWMRYSVFWYSQQLTQRLGQARFASYTQRFGYGNADVAPG
PGEFAGMKGAWNSGSLRIAPREQIAFLRAIVNRTLPVSAHAFEMTDRITLIDAQPDGWIVHGKTGTSSPGDDGRFDRARA
YGWFVGWAARGTRAVVFAHLIQDDAPHDVSAGLRARDALLAELPALALPAAGAVPPAR

Sequences:

>Translated_298_residues
MLPSHSPRPWPARAGLPRVDTARALAALTLLAAALASPPAGADTRTLCTIVADAASGRVLAERGEGCATRVTPASTFKIA
LSLMGFDAGVLTDAHAPVLPFRAGYPDWGGDAWRQPTDPARWMRYSVFWYSQQLTQRLGQARFASYTQRFGYGNADVAPG
PGEFAGMKGAWNSGSLRIAPREQIAFLRAIVNRTLPVSAHAFEMTDRITLIDAQPDGWIVHGKTGTSSPGDDGRFDRARA
YGWFVGWAARGTRAVVFAHLIQDDAPHDVSAGLRARDALLAELPALALPAAGAVPPAR
>Mature_298_residues
MLPSHSPRPWPARAGLPRVDTARALAALTLLAAALASPPAGADTRTLCTIVADAASGRVLAERGEGCATRVTPASTFKIA
LSLMGFDAGVLTDAHAPVLPFRAGYPDWGGDAWRQPTDPARWMRYSVFWYSQQLTQRLGQARFASYTQRFGYGNADVAPG
PGEFAGMKGAWNSGSLRIAPREQIAFLRAIVNRTLPVSAHAFEMTDRITLIDAQPDGWIVHGKTGTSSPGDDGRFDRARA
YGWFVGWAARGTRAVVFAHLIQDDAPHDVSAGLRARDALLAELPALALPAAGAVPPAR

Specific function: Oxacillin-hydrolyzing beta-lactamase. Confers resistance to beta-lactam antibiotics but at a significantly lower level than the TEM bla gene product [H]

COG id: COG2602

COG function: function code V; Beta-lactamase class D

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-D beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR002137
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00905 Transpeptidase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 31778; Mature: 31778

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS00337 BETA_LACTAMASE_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSHSPRPWPARAGLPRVDTARALAALTLLAAALASPPAGADTRTLCTIVADAASGRVL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCCCCEE
AERGEGCATRVTPASTFKIALSLMGFDAGVLTDAHAPVLPFRAGYPDWGGDAWRQPTDPA
EECCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
RWMRYSVFWYSQQLTQRLGQARFASYTQRFGYGNADVAPGPGEFAGMKGAWNSGSLRIAP
HHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
REQIAFLRAIVNRTLPVSAHAFEMTDRITLIDAQPDGWIVHGKTGTSSPGDDGRFDRARA
HHHHHHHHHHHHCCCCCCCCEEEECCEEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHH
YGWFVGWAARGTRAVVFAHLIQDDAPHDVSAGLRARDALLAELPALALPAAGAVPPAR
HEEEEEECCCCCHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MLPSHSPRPWPARAGLPRVDTARALAALTLLAAALASPPAGADTRTLCTIVADAASGRVL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHEEEEEECCCCCCEE
AERGEGCATRVTPASTFKIALSLMGFDAGVLTDAHAPVLPFRAGYPDWGGDAWRQPTDPA
EECCCCCEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHH
RWMRYSVFWYSQQLTQRLGQARFASYTQRFGYGNADVAPGPGEFAGMKGAWNSGSLRIAP
HHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEECC
REQIAFLRAIVNRTLPVSAHAFEMTDRITLIDAQPDGWIVHGKTGTSSPGDDGRFDRARA
HHHHHHHHHHHHCCCCCCCCEEEECCEEEEEECCCCCEEEECCCCCCCCCCCCCCHHHHH
YGWFVGWAARGTRAVVFAHLIQDDAPHDVSAGLRARDALLAELPALALPAAGAVPPAR
HEEEEEECCCCCHHHHHHHHHHCCCCCHHHHCHHHHHHHHHHCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9756755 [H]