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The map label for this gene is lrp [H]

Identifier: 238024737

GI number: 238024737

Start: 1760803

End: 1761318

Strand: Direct

Name: lrp [H]

Synonym: bglu_2g13740

Alternate gene names: 238024737

Gene position: 1760803-1761318 (Clockwise)

Preceding gene: 238024732

Following gene: 238024742

Centisome position: 62.28

GC content: 66.67

Gene sequence:

>516_bases
ATGTGCGCAATAAAAAAAACCACCAGCCGGGCCACCGCCGCAGCCGCAGCCGCCGGGGCGGAGCTCGACCGCGTCGATCG
CGCGATCCTGCGCGCGCTGCAGCGCGACGCGTCGATCTCCAACGTGGCGCTGGCCGCGCGCGTGAACCTGAGCCCGCCCG
CCTGCCTGCGCCGCGTGGAGAAGCTCAGGGAGGCCGGACTGATACGCGGCATCGTCGCGCTGCTCGAGCCGAAGGCGTTG
AACGCGGGCATGCTGGTGATGATCGGCGTGGTGCTGGACCGCTCGACGCCCGAGTCGTTCGCCGCGTTCGAGAAGGCCGC
ACAGAAGGTGTCCGGCTGCATGGAATGCCACGTGGTGACAGGCGAATTCGACGCCTTCATGCTGGTGCGCACACGCGACA
GCGAGACCTTCAACCGGCTGCACGCGGAACAGCTGCTCTACCTGCCGGGGGTTCGGCAGATCCGCACCTTCGTGGTGTTG
AAGGAAATCCTCTCGACGACGCAATTTCCGGTTTGA

Upstream 100 bases:

>100_bases
GAAACGACTGTACGAATCAGGGTTGCAAATCGATGGCTGTTTTTCGGTGATTCGAAGGCTCGGTTCACGGATGGATTAAT
TTCGAAAGGATTCTTGGCCG

Downstream 100 bases:

>100_bases
ACGGCGCAGCCGCCGGGCGTGGCGAGGATGGCGGCCCAGGCGATGCGGGCCGCGAAGCAAGGCCGTGCGCCGCACCGGCA
GCGGCCGTTTCCGGATGCTC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MCAIKKTTSRATAAAAAAGAELDRVDRAILRALQRDASISNVALAARVNLSPPACLRRVEKLREAGLIRGIVALLEPKAL
NAGMLVMIGVVLDRSTPESFAAFEKAAQKVSGCMECHVVTGEFDAFMLVRTRDSETFNRLHAEQLLYLPGVRQIRTFVVL
KEILSTTQFPV

Sequences:

>Translated_171_residues
MCAIKKTTSRATAAAAAAGAELDRVDRAILRALQRDASISNVALAARVNLSPPACLRRVEKLREAGLIRGIVALLEPKAL
NAGMLVMIGVVLDRSTPESFAAFEKAAQKVSGCMECHVVTGEFDAFMLVRTRDSETFNRLHAEQLLYLPGVRQIRTFVVL
KEILSTTQFPV
>Mature_171_residues
MCAIKKTTSRATAAAAAAGAELDRVDRAILRALQRDASISNVALAARVNLSPPACLRRVEKLREAGLIRGIVALLEPKAL
NAGMLVMIGVVLDRSTPESFAAFEKAAQKVSGCMECHVVTGEFDAFMLVRTRDSETFNRLHAEQLLYLPGVRQIRTFVVL
KEILSTTQFPV

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=151, Percent_Identity=44.3708609271523, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=26.6666666666667, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI1790182, Length=151, Percent_Identity=26.4900662251656, Blast_Score=61, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18595; Mature: 18595

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCAIKKTTSRATAAAAAAGAELDRVDRAILRALQRDASISNVALAARVNLSPPACLRRVE
CCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCHHHHHHHH
KLREAGLIRGIVALLEPKALNAGMLVMIGVVLDRSTPESFAAFEKAAQKVSGCMECHVVT
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEEE
GEFDAFMLVRTRDSETFNRLHAEQLLYLPGVRQIRTFVVLKEILSTTQFPV
CCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MCAIKKTTSRATAAAAAAGAELDRVDRAILRALQRDASISNVALAARVNLSPPACLRRVE
CCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHEEEEEEECCCCHHHHHHHH
KLREAGLIRGIVALLEPKALNAGMLVMIGVVLDRSTPESFAAFEKAAQKVSGCMECHVVT
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEEE
GEFDAFMLVRTRDSETFNRLHAEQLLYLPGVRQIRTFVVLKEILSTTQFPV
CCCCEEEEEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]