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The map label for this gene is ahpC [H]

Identifier: 238024730

GI number: 238024730

Start: 1753282

End: 1753845

Strand: Direct

Name: ahpC [H]

Synonym: bglu_2g13670

Alternate gene names: 238024730

Gene position: 1753282-1753845 (Clockwise)

Preceding gene: 238024728

Following gene: 238024731

Centisome position: 62.01

GC content: 62.41

Gene sequence:

>564_bases
ATGCCGATCATCAACAGCCAGATCAAACCGTTCAAGGCAACCGCATATCACAACGGCGACTTCGTTCCCGTCAGCGACGA
ATCGCTGAAGGGCAAGTGGTCGGTCGTCGTGTTCTATCCGGCGGACTTCACGTTCGTGTGCCCGACGGAGCTGGGCGACC
TGGCCGATCGTTACGAAGAATTCCAGAAGCTGGGCGTCGAGATCTACGGCGTGTCGACCGATACGCACTTCACGCACAAG
GCATGGCACGACACCTCGGACACGATCGCGAAGATCAAGTACCCGCTGGTCGGCGACCCGACGGCCACGCTGGCACGCGC
GTTCGACGTGCTGATCGAGGAAGAAGGCCTGGCGCTGCGCGGCACGTTCGTGATCAACCCGGAAGGCGAGATCAAGATCG
CTGAAATCCACGACAACGGCATCGGCCGCGACGCAGGCGAACTGCTGCGCAAGGTGCAGGCCGCTCAATACGTCGCCTCG
CACCCGGGTGAAGTCTGCCCCGCGAAGTGGACGCCGGGCGCCGAAACGCTGACCCCGTCGCTCGACCTGGTCGGCAAGAT
CTAA

Upstream 100 bases:

>100_bases
AAATCTCGATCCCCGTCATTGAAACAAGCAATTTCACATTCGCTCCCCCAATCGTCATACTGGCCGCTCCTGATCACTCA
CTGACCAAAGGAAGACCCAA

Downstream 100 bases:

>100_bases
GCGTCGTTCGCATCAGACGGACCGGGGCGCCGCGAGGCGCTCCGCCGTGCGGCCCTCGCGCCGCACGCCCCCTCGCCCGC
CGGCGAGGTGCCAAAAACAT

Product: Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MPIINSQIKPFKATAYHNGDFVPVSDESLKGKWSVVVFYPADFTFVCPTELGDLADRYEEFQKLGVEIYGVSTDTHFTHK
AWHDTSDTIAKIKYPLVGDPTATLARAFDVLIEEEGLALRGTFVINPEGEIKIAEIHDNGIGRDAGELLRKVQAAQYVAS
HPGEVCPAKWTPGAETLTPSLDLVGKI

Sequences:

>Translated_187_residues
MPIINSQIKPFKATAYHNGDFVPVSDESLKGKWSVVVFYPADFTFVCPTELGDLADRYEEFQKLGVEIYGVSTDTHFTHK
AWHDTSDTIAKIKYPLVGDPTATLARAFDVLIEEEGLALRGTFVINPEGEIKIAEIHDNGIGRDAGELLRKVQAAQYVAS
HPGEVCPAKWTPGAETLTPSLDLVGKI
>Mature_186_residues
PIINSQIKPFKATAYHNGDFVPVSDESLKGKWSVVVFYPADFTFVCPTELGDLADRYEEFQKLGVEIYGVSTDTHFTHKA
WHDTSDTIAKIKYPLVGDPTATLARAFDVLIEEEGLALRGTFVINPEGEIKIAEIHDNGIGRDAGELLRKVQAAQYVASH
PGEVCPAKWTPGAETLTPSLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=179, Percent_Identity=45.8100558659218, Blast_Score=161, Evalue=3e-40,
Organism=Homo sapiens, GI5802974, Length=182, Percent_Identity=44.5054945054945, Blast_Score=160, Evalue=4e-40,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=45.7142857142857, Blast_Score=156, Evalue=8e-39,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=44.5714285714286, Blast_Score=154, Evalue=4e-38,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=44.5714285714286, Blast_Score=154, Evalue=4e-38,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=44.5714285714286, Blast_Score=154, Evalue=4e-38,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=41.1111111111111, Blast_Score=141, Evalue=3e-34,
Organism=Homo sapiens, GI33188454, Length=74, Percent_Identity=54.0540540540541, Blast_Score=88, Evalue=4e-18,
Organism=Homo sapiens, GI4758638, Length=161, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=66.3101604278075, Blast_Score=275, Evalue=9e-76,
Organism=Caenorhabditis elegans, GI193204376, Length=174, Percent_Identity=43.1034482758621, Blast_Score=151, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI32565831, Length=174, Percent_Identity=43.1034482758621, Blast_Score=151, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17554494, Length=179, Percent_Identity=41.8994413407821, Blast_Score=150, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=27.4390243902439, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=39.2265193370166, Blast_Score=138, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6323613, Length=182, Percent_Identity=39.5604395604396, Blast_Score=135, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6319407, Length=163, Percent_Identity=31.2883435582822, Blast_Score=88, Evalue=7e-19,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=41.2429378531073, Blast_Score=156, Evalue=1e-38,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=41.3612565445026, Blast_Score=153, Evalue=6e-38,
Organism=Drosophila melanogaster, GI24656348, Length=181, Percent_Identity=42.5414364640884, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI17864676, Length=181, Percent_Identity=42.5414364640884, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI17157991, Length=180, Percent_Identity=40.5555555555556, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24641739, Length=180, Percent_Identity=40.5555555555556, Blast_Score=143, Evalue=8e-35,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=31.0126582278481, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24652436, Length=158, Percent_Identity=31.0126582278481, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=31.0126582278481, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24581278, Length=158, Percent_Identity=31.0126582278481, Blast_Score=85, Evalue=2e-17,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20516; Mature: 20385

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIINSQIKPFKATAYHNGDFVPVSDESLKGKWSVVVFYPADFTFVCPTELGDLADRYEE
CCCCCCCCCCEEEEEEECCCEEECCCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKLGVEIYGVSTDTHFTHKAWHDTSDTIAKIKYPLVGDPTATLARAFDVLIEEEGLALR
HHHCCEEEEEECCCCCEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEE
GTFVINPEGEIKIAEIHDNGIGRDAGELLRKVQAAQYVASHPGEVCPAKWTPGAETLTPS
EEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LDLVGKI
HHEEECC
>Mature Secondary Structure 
PIINSQIKPFKATAYHNGDFVPVSDESLKGKWSVVVFYPADFTFVCPTELGDLADRYEE
CCCCCCCCCEEEEEEECCCEEECCCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKLGVEIYGVSTDTHFTHKAWHDTSDTIAKIKYPLVGDPTATLARAFDVLIEEEGLALR
HHHCCEEEEEECCCCCEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCCEEE
GTFVINPEGEIKIAEIHDNGIGRDAGELLRKVQAAQYVASHPGEVCPAKWTPGAETLTPS
EEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
LDLVGKI
HHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]