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The map label for this gene is ccpA [H]

Identifier: 23100865

GI number: 23100865

Start: 3547926

End: 3548885

Strand: Reverse

Name: ccpA [H]

Synonym: OB3410

Alternate gene names: 23100865

Gene position: 3548885-3547926 (Counterclockwise)

Preceding gene: 23100868

Following gene: 23100861

Centisome position: 97.75

GC content: 36.88

Gene sequence:

>960_bases
ATGGCCGTAACATTAAAGGATATAGCGATAGAATGTGGAGTGAGCTATTCAACGGTGAGTAAGGCACTTAAAAACTCTCC
GCTCGTGACGGAAGCAACGAAAAGAAAGATTAAAGAGAAAGCAGAAGAAATGAATTATATCCCAAATAATTCTGCACGAT
CTTTGGTTTCTAATAAAAGTAATACCGTTGGCTTAATATGGCCTGCAGTAGATAGAGTAGCTGTCACCACACTTGCTTCT
CAAATAAATGAGGCAGTAAAAAAAGCGGGTTATTTTATGGTAGTGTCAATTGATGATCCGATAACTGCTGCAGGGAAATT
TTTGGAGTTGCGTTTTGATGGAGTGATCGTTTTTGATGAAGGGGAAGAAACGCGACTGCCTGCTAAAATATCAAATAATA
TTCCTGTAGTTGCCTATGGTGTAGAGCAAAAACTAGATTATCCAATCATTAATGTTAATCACGATAAATCTATGCAACTA
GCGGTAGACACCCTAATAGACAAAGGGAATAGAGAAATAGATTATATCGGTGATCTTGAAACGAAGGATATCCGACAAAT
TATAAAGAAAGAAACGTTCATTCGCTATTGTGAAGAAAAGAAAATCAATTATCGACTAATCGATTCAGAAGGGTTGTCCG
AAGAGGTAACGAGCAACTCGTTAAGGAAATTTCTCATGAAGAATACGCTTAAAAAAGGAATTATATGTGGTAGTTATGAT
ATTACGATGGGTTTACTACATCATATGGATAAACAAGCGGAAAAGCCAATGATTGTTTCTTACGATAATATTAAAAAATT
TGATGCGATTGATACGCCAGTACATACAGTTGGAGTTCCTTCTGAAAAAATCGCAGAGAGTTTAGTTCAAATGCTGATGA
AACATATCGAAGCGGAAGGCGTAGTAGAAGATCAAGTGATGCAATTATACCCCGAAGTTACGTTTCCCGAAGATGAGTGA

Upstream 100 bases:

>100_bases
CAACGTTGTTATTTTTTAGTTTGAAATATTCATAACAGTTAATTATTATGATATAATTATCTGACAGATAAATCAATAGA
GAATTTTAAGGAGTTATAAA

Downstream 100 bases:

>100_bases
TTTTGAATTGCTTACAGAAAAATAACAGGACGGTTGGTAGGATAAAACAAGTCTATTCACAAACTAACAGAAAATAAGAA
ATGTTTTGGTGTTCTAAAAC

Product: transcriptional regulator

Products: NA

Alternate protein names: Glucose-resistance amylase regulator [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MAVTLKDIAIECGVSYSTVSKALKNSPLVTEATKRKIKEKAEEMNYIPNNSARSLVSNKSNTVGLIWPAVDRVAVTTLAS
QINEAVKKAGYFMVVSIDDPITAAGKFLELRFDGVIVFDEGEETRLPAKISNNIPVVAYGVEQKLDYPIINVNHDKSMQL
AVDTLIDKGNREIDYIGDLETKDIRQIIKKETFIRYCEEKKINYRLIDSEGLSEEVTSNSLRKFLMKNTLKKGIICGSYD
ITMGLLHHMDKQAEKPMIVSYDNIKKFDAIDTPVHTVGVPSEKIAESLVQMLMKHIEAEGVVEDQVMQLYPEVTFPEDE

Sequences:

>Translated_319_residues
MAVTLKDIAIECGVSYSTVSKALKNSPLVTEATKRKIKEKAEEMNYIPNNSARSLVSNKSNTVGLIWPAVDRVAVTTLAS
QINEAVKKAGYFMVVSIDDPITAAGKFLELRFDGVIVFDEGEETRLPAKISNNIPVVAYGVEQKLDYPIINVNHDKSMQL
AVDTLIDKGNREIDYIGDLETKDIRQIIKKETFIRYCEEKKINYRLIDSEGLSEEVTSNSLRKFLMKNTLKKGIICGSYD
ITMGLLHHMDKQAEKPMIVSYDNIKKFDAIDTPVHTVGVPSEKIAESLVQMLMKHIEAEGVVEDQVMQLYPEVTFPEDE
>Mature_318_residues
AVTLKDIAIECGVSYSTVSKALKNSPLVTEATKRKIKEKAEEMNYIPNNSARSLVSNKSNTVGLIWPAVDRVAVTTLASQ
INEAVKKAGYFMVVSIDDPITAAGKFLELRFDGVIVFDEGEETRLPAKISNNIPVVAYGVEQKLDYPIINVNHDKSMQLA
VDTLIDKGNREIDYIGDLETKDIRQIIKKETFIRYCEEKKINYRLIDSEGLSEEVTSNSLRKFLMKNTLKKGIICGSYDI
TMGLLHHMDKQAEKPMIVSYDNIKKFDAIDTPVHTVGVPSEKIAESLVQMLMKHIEAEGVVEDQVMQLYPEVTFPEDE

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (AmyE) and the acetyl-coenzyme A synthetase (AcsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=317, Percent_Identity=23.0283911671924, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790194, Length=328, Percent_Identity=24.390243902439, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787948, Length=329, Percent_Identity=23.1003039513678, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786540, Length=211, Percent_Identity=25.1184834123223, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790715, Length=261, Percent_Identity=24.5210727969349, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 35782; Mature: 35650

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVTLKDIAIECGVSYSTVSKALKNSPLVTEATKRKIKEKAEEMNYIPNNSARSLVSNKS
CEEEHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCC
NTVGLIWPAVDRVAVTTLASQINEAVKKAGYFMVVSIDDPITAAGKFLELRFDGVIVFDE
CEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEECEEEEEEC
GEETRLPAKISNNIPVVAYGVEQKLDYPIINVNHDKSMQLAVDTLIDKGNREIDYIGDLE
CCCCCCCHHHCCCCCEEEECCHHCCCCCEEECCCCCCHHHHHHHHHHCCCCCEEEECCCC
TKDIRQIIKKETFIRYCEEKKINYRLIDSEGLSEEVTSNSLRKFLMKNTLKKGIICGSYD
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCEEECCHH
ITMGLLHHMDKQAEKPMIVSYDNIKKFDAIDTPVHTVGVPSEKIAESLVQMLMKHIEAEG
HHHHHHHHHHHHHCCCEEEEECCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
VVEDQVMQLYPEVTFPEDE
CHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
AVTLKDIAIECGVSYSTVSKALKNSPLVTEATKRKIKEKAEEMNYIPNNSARSLVSNKS
EEEHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCC
NTVGLIWPAVDRVAVTTLASQINEAVKKAGYFMVVSIDDPITAAGKFLELRFDGVIVFDE
CEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCEEEEEECEEEEEEC
GEETRLPAKISNNIPVVAYGVEQKLDYPIINVNHDKSMQLAVDTLIDKGNREIDYIGDLE
CCCCCCCHHHCCCCCEEEECCHHCCCCCEEECCCCCCHHHHHHHHHHCCCCCEEEECCCC
TKDIRQIIKKETFIRYCEEKKINYRLIDSEGLSEEVTSNSLRKFLMKNTLKKGIICGSYD
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCEEECCHH
ITMGLLHHMDKQAEKPMIVSYDNIKKFDAIDTPVHTVGVPSEKIAESLVQMLMKHIEAEG
HHHHHHHHHHHHHCCCEEEEECCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
VVEDQVMQLYPEVTFPEDE
CHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1904524; 9387221; 9384377 [H]