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The map label for this gene is gfo [H]

Identifier: 23100716

GI number: 23100716

Start: 3397537

End: 3398511

Strand: Reverse

Name: gfo [H]

Synonym: OB3261

Alternate gene names: 23100716

Gene position: 3398511-3397537 (Counterclockwise)

Preceding gene: 23100718

Following gene: 23100715

Centisome position: 93.61

GC content: 43.59

Gene sequence:

>975_bases
ATGAAGTATAAGAAGGTGCGTTGGGGTATTATTGGTTGCGGTGATGTAACGGAGGTAAAAAGTGGACCGGCATTTCAAAA
GGTAGATCATTCTGAGCTAGTGGCAGTCATGCGAAGAACAGGGGAACTTGCTAAGGACTATGCAAAAAGGCATAACGTGC
CAACCTGGTATGATGATGCGGATGCTTTAATCAACGATGCGAATGTAGATGCCGTGTATATCGCGACGCCACCAGGTTCC
CATAAAGAGTATACTCTGAAGGTAGCTCAGGCAGGGAAACCTGTATATGTCGAAAAACCAATGGCATTGAACGAAGCAGA
ATGCCAGCAAATGATCCAGGCGTGTAAGGATGCAGGCGTTCCGCTGTATGTCGCATATTATCGCAGAGCACAACCTAGAT
TTAAAAAAGTGAAGGAATTACTTGATGCCAAGACAATAGGCGACGTGCGTTTTGTCTCAACGACGCAATATCAAAAAGTC
TCAGAAGATATAAAGGCATCATCACTACCATGGAGATTACAACCCGAAATATCGGGCGGAGGACTGTTTTTTGACCTTGC
CAGCCATACATTAGATATTCTTGATTTCTTACTTGGGCCAATTGAAGAGGTGCATGGAATGAAGTCCAATCAAGCGGAAT
ACTATGAAGCAGAAGATATTGTTACTGGCACTTATCGATTCCAATCTGGCGTGCATGGAGTTGGGAATTGGTGTTTCACT
GCTTTTGAGAATATAGATAAAAATGAAATTGTTGGCAGTAAGGGGAAGATAACCTTTTCTACCTTTGGGGATGATCCTAT
CATTCTGACAACTGCCGATGGACAGGAAGAATGGACATTTGAACGTCCAAAACATGTCCATCAACCGCTAATTGAATCGA
TCGTGAAGGATCTAACCTCAGATTCTAAACAAGCCCCAAGCACTGGTGAAAGTGGCGCTAGGACAAATTGGGTGATGGAT
CAGTTAACGGAATGA

Upstream 100 bases:

>100_bases
AGTTGATCGCTTAATAAGACAAAACTCATATCCGAAAGCGCGTATTAGTGGTACACTACACATAAACTGAACATGCGTTT
AAAGGGGAGTGGGATAACGA

Downstream 100 bases:

>100_bases
CAGATAGTAAAATAACGTTAATCCGAATGATTAGGTGTTAAAAAATCAAGTCAAAAATTTACTTCGCTTATTCTAAAGCG
GCAGGCGAGCCTTCTGATGC

Product: oxidoreductase

Products: NA

Alternate protein names: GFOR [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKYKKVRWGIIGCGDVTEVKSGPAFQKVDHSELVAVMRRTGELAKDYAKRHNVPTWYDDADALINDANVDAVYIATPPGS
HKEYTLKVAQAGKPVYVEKPMALNEAECQQMIQACKDAGVPLYVAYYRRAQPRFKKVKELLDAKTIGDVRFVSTTQYQKV
SEDIKASSLPWRLQPEISGGGLFFDLASHTLDILDFLLGPIEEVHGMKSNQAEYYEAEDIVTGTYRFQSGVHGVGNWCFT
AFENIDKNEIVGSKGKITFSTFGDDPIILTTADGQEEWTFERPKHVHQPLIESIVKDLTSDSKQAPSTGESGARTNWVMD
QLTE

Sequences:

>Translated_324_residues
MKYKKVRWGIIGCGDVTEVKSGPAFQKVDHSELVAVMRRTGELAKDYAKRHNVPTWYDDADALINDANVDAVYIATPPGS
HKEYTLKVAQAGKPVYVEKPMALNEAECQQMIQACKDAGVPLYVAYYRRAQPRFKKVKELLDAKTIGDVRFVSTTQYQKV
SEDIKASSLPWRLQPEISGGGLFFDLASHTLDILDFLLGPIEEVHGMKSNQAEYYEAEDIVTGTYRFQSGVHGVGNWCFT
AFENIDKNEIVGSKGKITFSTFGDDPIILTTADGQEEWTFERPKHVHQPLIESIVKDLTSDSKQAPSTGESGARTNWVMD
QLTE
>Mature_324_residues
MKYKKVRWGIIGCGDVTEVKSGPAFQKVDHSELVAVMRRTGELAKDYAKRHNVPTWYDDADALINDANVDAVYIATPPGS
HKEYTLKVAQAGKPVYVEKPMALNEAECQQMIQACKDAGVPLYVAYYRRAQPRFKKVKELLDAKTIGDVRFVSTTQYQKV
SEDIKASSLPWRLQPEISGGGLFFDLASHTLDILDFLLGPIEEVHGMKSNQAEYYEAEDIVTGTYRFQSGVHGVGNWCFT
AFENIDKNEIVGSKGKITFSTFGDDPIILTTADGQEEWTFERPKHVHQPLIESIVKDLTSDSKQAPSTGESGARTNWVMD
QLTE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Homo sapiens, GI7657212, Length=256, Percent_Identity=25, Blast_Score=82, Evalue=4e-16,
Organism=Escherichia coli, GI87082405, Length=203, Percent_Identity=32.0197044334975, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787574, Length=271, Percent_Identity=24.3542435424354, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI145693182, Length=290, Percent_Identity=23.448275862069, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081947, Length=195, Percent_Identity=28.7179487179487, Blast_Score=64, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323975, Length=278, Percent_Identity=27.3381294964029, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24581117, Length=285, Percent_Identity=28.4210526315789, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24581115, Length=284, Percent_Identity=26.056338028169, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008354
- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.99.28 [H]

Molecular weight: Translated: 36206; Mature: 36206

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYKKVRWGIIGCGDVTEVKSGPAFQKVDHSELVAVMRRTGELAKDYAKRHNVPTWYDDA
CCCCEEEEEEEECCCHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
DALINDANVDAVYIATPPGSHKEYTLKVAQAGKPVYVEKPMALNEAECQQMIQACKDAGV
HHHCCCCCCCEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCC
PLYVAYYRRAQPRFKKVKELLDAKTIGDVRFVSTTQYQKVSEDIKASSLPWRLQPEISGG
CEEEEHHHHCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCCCEEECCCCCCC
GLFFDLASHTLDILDFLLGPIEEVHGMKSNQAEYYEAEDIVTGTYRFQSGVHGVGNWCFT
EEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEEEHHHCCCCHHHHHHHH
AFENIDKNEIVGSKGKITFSTFGDDPIILTTADGQEEWTFERPKHVHQPLIESIVKDLTS
HHHCCCHHHCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCC
DSKQAPSTGESGARTNWVMDQLTE
CCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MKYKKVRWGIIGCGDVTEVKSGPAFQKVDHSELVAVMRRTGELAKDYAKRHNVPTWYDDA
CCCCEEEEEEEECCCHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
DALINDANVDAVYIATPPGSHKEYTLKVAQAGKPVYVEKPMALNEAECQQMIQACKDAGV
HHHCCCCCCCEEEEECCCCCCCEEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHCCC
PLYVAYYRRAQPRFKKVKELLDAKTIGDVRFVSTTQYQKVSEDIKASSLPWRLQPEISGG
CEEEEHHHHCCHHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCCCEEECCCCCCC
GLFFDLASHTLDILDFLLGPIEEVHGMKSNQAEYYEAEDIVTGTYRFQSGVHGVGNWCFT
EEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEECCCEEEEEEHHHCCCCHHHHHHHH
AFENIDKNEIVGSKGKITFSTFGDDPIILTTADGQEEWTFERPKHVHQPLIESIVKDLTS
HHHCCCHHHCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCC
DSKQAPSTGESGARTNWVMDQLTE
CCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1537789; 8472911; 8994968 [H]