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The map label for this gene is sdhB [H]

Identifier: 229918344

GI number: 229918344

Start: 2595651

End: 2596451

Strand: Direct

Name: sdhB [H]

Synonym: EAT1b_2629

Alternate gene names: 229918344

Gene position: 2595651-2596451 (Clockwise)

Preceding gene: 229918343

Following gene: 229918345

Centisome position: 86.52

GC content: 53.43

Gene sequence:

>801_bases
ATGACGACGCCAATGCAATCTGAACAAAAAGACATCCGCTTCATCATTGAACGCCAAGATGGACCGGATCAAGCGACGTA
TACGGAAGAATTCACGGTACCATACCGTCCAAACATGAACGTCATCTCGGCATTGATGGAAATCCGCCGTAACCCGGTCA
ACGCGAACGGGGACAAGACGACACCGATCAACTGGGACATGAACTGTCTTGAAGAAGTATGTGGTGCCTGTTCGATGATC
ATCAACGGGAAGCCGCGCCAATCGTGTACGGCACTCGTCGATAAACTCGAGCAACCGATCCGTCTTGCGCCGATGAAGAC
GTTCCCGGTCATCCGTGACCTTCAAGTCGACCGTCAACGCATGTTCGACGCGTTGAAAAAAGTGAAGGCATGGGTCCCGA
TCGATGGCACATACGACCTCGGTCCAGGACCGCGTATGCCGGAGAACAAACGTCAATGGGCGTACGAATTATCGAAATGT
ATGACGTGTGGCGTTTGTCTTGAAGCGTGTCCGAACGTGAACGACAAATCGGACTTCATCGGTCCAGCGGCGATTTCGCA
AGTCCGACTCTTCAACTCACACCCAACAGGTGCCTTCCACGCCGAAGACCGCCTCGAGGCACTTATGGAAGACGGTGGCA
TCATGCAGTGCGGAAACGCACAAAACTGTGTCGAAGTTTGTCCGAAGGGCATCCCGCTCACGACGTCGATCGCTTCGATG
AACCGTCAAACGACGCTTCACTCGTTCAAACAGTTCTTCGGTAGTGACAAAGGTCGCACCGGTTCTGCGGTCGAGGCGTA
A

Upstream 100 bases:

>100_bases
GTTACAAAGATGGGGAAGTCGATATCTCGTATGAAGACATCGATGTTTCGTTAATCCCGCCACGTAAACGGGATTACTCG
AAGAAAGGGGCGAAGACGAA

Downstream 100 bases:

>100_bases
GCGAGCCGATGACCAAGTACTTTCGAGAGCCAGGTTGGGAAACACGTGTCAAAAGAGGGATCGCGCTCGATGTGAAAGTT
CGCTTTTCGGAGTGCGACCC

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MTTPMQSEQKDIRFIIERQDGPDQATYTEEFTVPYRPNMNVISALMEIRRNPVNANGDKTTPINWDMNCLEEVCGACSMI
INGKPRQSCTALVDKLEQPIRLAPMKTFPVIRDLQVDRQRMFDALKKVKAWVPIDGTYDLGPGPRMPENKRQWAYELSKC
MTCGVCLEACPNVNDKSDFIGPAAISQVRLFNSHPTGAFHAEDRLEALMEDGGIMQCGNAQNCVEVCPKGIPLTTSIASM
NRQTTLHSFKQFFGSDKGRTGSAVEA

Sequences:

>Translated_266_residues
MTTPMQSEQKDIRFIIERQDGPDQATYTEEFTVPYRPNMNVISALMEIRRNPVNANGDKTTPINWDMNCLEEVCGACSMI
INGKPRQSCTALVDKLEQPIRLAPMKTFPVIRDLQVDRQRMFDALKKVKAWVPIDGTYDLGPGPRMPENKRQWAYELSKC
MTCGVCLEACPNVNDKSDFIGPAAISQVRLFNSHPTGAFHAEDRLEALMEDGGIMQCGNAQNCVEVCPKGIPLTTSIASM
NRQTTLHSFKQFFGSDKGRTGSAVEA
>Mature_265_residues
TTPMQSEQKDIRFIIERQDGPDQATYTEEFTVPYRPNMNVISALMEIRRNPVNANGDKTTPINWDMNCLEEVCGACSMII
NGKPRQSCTALVDKLEQPIRLAPMKTFPVIRDLQVDRQRMFDALKKVKAWVPIDGTYDLGPGPRMPENKRQWAYELSKCM
TCGVCLEACPNVNDKSDFIGPAAISQVRLFNSHPTGAFHAEDRLEALMEDGGIMQCGNAQNCVEVCPKGIPLTTSIASMN
RQTTLHSFKQFFGSDKGRTGSAVEA

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=247, Percent_Identity=25.5060728744939, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1790596, Length=250, Percent_Identity=26, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786943, Length=246, Percent_Identity=29.2682926829268, Blast_Score=89, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17533915, Length=209, Percent_Identity=22.488038277512, Blast_Score=64, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322987, Length=211, Percent_Identity=23.2227488151659, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24643156, Length=197, Percent_Identity=24.8730964467005, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17137106, Length=249, Percent_Identity=23.2931726907631, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29670; Mature: 29539

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
9.0 %Cys+Met (Translated Protein)
4.2 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
8.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPMQSEQKDIRFIIERQDGPDQATYTEEFTVPYRPNMNVISALMEIRRNPVNANGDKT
CCCCCCCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
TPINWDMNCLEEVCGACSMIINGKPRQSCTALVDKLEQPIRLAPMKTFPVIRDLQVDRQR
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHH
MFDALKKVKAWVPIDGTYDLGPGPRMPENKRQWAYELSKCMTCGVCLEACPNVNDKSDFI
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCC
GPAAISQVRLFNSHPTGAFHAEDRLEALMEDGGIMQCGNAQNCVEVCPKGIPLTTSIASM
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHCCCCCCCHHHHHHH
NRQTTLHSFKQFFGSDKGRTGSAVEA
HHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TTPMQSEQKDIRFIIERQDGPDQATYTEEFTVPYRPNMNVISALMEIRRNPVNANGDKT
CCCCCCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCC
TPINWDMNCLEEVCGACSMIINGKPRQSCTALVDKLEQPIRLAPMKTFPVIRDLQVDRQR
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHH
MFDALKKVKAWVPIDGTYDLGPGPRMPENKRQWAYELSKCMTCGVCLEACPNVNDKSDFI
HHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCC
GPAAISQVRLFNSHPTGAFHAEDRLEALMEDGGIMQCGNAQNCVEVCPKGIPLTTSIASM
CHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHCCCCCCCHHHHHHH
NRQTTLHSFKQFFGSDKGRTGSAVEA
HHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3027051; 8969504; 9384377; 3114423 [H]