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The map label for this gene is resE [H]

Identifier: 229917679

GI number: 229917679

Start: 1916108

End: 1918063

Strand: Reverse

Name: resE [H]

Synonym: EAT1b_1956

Alternate gene names: 229917679

Gene position: 1918063-1916108 (Counterclockwise)

Preceding gene: 229917682

Following gene: 229917677

Centisome position: 63.94

GC content: 48.42

Gene sequence:

>1956_bases
ATGAAGTCATGGATTGACCAACGGATCGGGAGACAATTTTTATTCGTCTTCTACTTATTCATCGGACTGATCCTCCTCAC
GTCGCTTGCCGTATATGTGTATACGGAAAACCAAATCGAACAGACGACGTCATCGCTCGAGAACATCAGTGAACGACGCA
CAAATGCGACCGAGTTGTTCGAGACATGGCAGTCGATGCAATATGAAATGCGCGGATATGTCCTCCTTGGGGATGACGCG
ATGTTAGAACGTGTGCAAGATAAACAAGTTTTGATTGACGAACAGACCTTTTGGTTCGAACAGAACGCAGTGACTGAGAA
AGAAAAAACGTACGCGAGCGATGCGCGCACACTGTTTGTTGCGTATCAGGAACGTGTCATGCCGAGCCTTGAACGTTATG
TAGCAGGAAAACGGGACGGGAGTGTGACCGAACCCTTCTTAAAGATGCCGACACTCGGGAAAGTGAATCCTCAAAAAGAC
CCACCGGCAGATCGTAAATTCAAAATCAATTCGAAAAGTGCGGCAGATATGAGTGCGAGCATCGTCGATATGGAAAGCGT
CTTCACGGAATACCGGAACTCACTGAACGCAGAAGAGGATGCGCTCCGTGCTCAGCTTGCGACCCATACGAAGTGGGCAC
AAGCTCTTTGGCTCCTCTCATTACTTGGCGTCCTCTTCATTCTCTTCATCGTCGCCCGTCCATATGTGAGACGCTTAACG
GGTCAACTGCAGGAGTTAATCGAAAACAGTAAGCGCCTTGCCGGAGAACGACAGCCAATCACACCGGCGGCAGCCCAATC
TAAAAATGAAGTCGGTCAATTGACAACATCGTTCCGACAGATGGCTACATCTCTCACGACACAACGCTATCGGATTGAAG
AAGAACGTGAGAAGACAGCGCGCCTTCTGCACTCGATTCGCGATGCCGTCATCTATGTCGAACACGCAACAAGCGAAAAA
GTAGCGAACCAAGCGTTGTTCGTCTTATTCAATCAACCGATCACGAAACGAAATGAAGTCGATTTATATCGTTTAGACGC
TAGCCTTGAGGAGCTTGGACTGCAGGTCGACCAAAAGGATGCCTTTTTCGCGTTCATGGAACGATCATTCGATGGACAGT
GTAAAGAAGAGAGCGTCACATTCTCGATGAATCAGGAGGAGCGCTTCATTCAAATGTATGCGGAGAAGATTTACTTGCGA
GGAACACGTCATGGAACGATGCTCGTTTTCCGTGACGTGACGCATGAGACCGAAGTCGACCGTCTGAAAACCGAACTCGT
TTCGACCGTCTCTCACGAACTCCGGACTCCGCTCACAAGTATTATCGGATTCACTGAACTTCTTCGTTTCCGAAAGCTTT
CAGCCGAACGTTCCGAAAAGTATTTAGGAATGATTCATCAAGAGACATTGCGTCTTGAAGACTTGATTTCAAACTTGCTC
GATGTACAACGGATGGAGTCTGGACAACAGACGTACCATAACGAACCGGAGCGTCTATCCGCCATTCTTGAACAAGCGAT
CGCGGTACATCAAGGCTCAAGCCAACATCATCACATCACGTTTGATTGCACGGAAGACGTCTATGTATACGGAGACCGGA
CGCGACTCAATCAACTCTTCATGAACCTCCTGCACAACGCTGTGAAGTATTCGCCTCGCGGTGGCGAAATCAATGTCCGT
GTCGCATGTGAACGACCGGATTGGATTGACATTTCAATTGAAGATCACGGTATCGGGATTCCCCAAACCGCGCTACCAAA
ATTGTTTGACAAGTTTTATCGCGTCGACAACTCCGCCAGTCGAAAAATCGGAGGGACCGGTCTCGGTCTCGCGATTTGTA
AAGAAATCGCCGAAGGTCACGGTGGAACGATTCACGCTACCTCAAACATCGGCAAAGGCTCTATGTTCACTGTCAGCCTT
CCCAAGTTGGATATGACCAATCAAATAAGTAGCTAA

Upstream 100 bases:

>100_bases
TCTAGCATCTGAAGAGTTGAATCTGTACAATGAAAGAACGACACTCGTAGGATATTAGTCACAGTCGGAATGTTCATCAT
TCTAGGAAGGAACGGTCTTT

Downstream 100 bases:

>100_bases
ACGAAAAGAGGGTGCATCAGCGCACCCTCTTGTTTATTGGACTTTGTTCTCTGGACCAAATGACGGATAGAGCGAAAGCC
CACCGTCCGCAAAGATGGTT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 651; Mature: 651

Protein sequence:

>651_residues
MKSWIDQRIGRQFLFVFYLFIGLILLTSLAVYVYTENQIEQTTSSLENISERRTNATELFETWQSMQYEMRGYVLLGDDA
MLERVQDKQVLIDEQTFWFEQNAVTEKEKTYASDARTLFVAYQERVMPSLERYVAGKRDGSVTEPFLKMPTLGKVNPQKD
PPADRKFKINSKSAADMSASIVDMESVFTEYRNSLNAEEDALRAQLATHTKWAQALWLLSLLGVLFILFIVARPYVRRLT
GQLQELIENSKRLAGERQPITPAAAQSKNEVGQLTTSFRQMATSLTTQRYRIEEEREKTARLLHSIRDAVIYVEHATSEK
VANQALFVLFNQPITKRNEVDLYRLDASLEELGLQVDQKDAFFAFMERSFDGQCKEESVTFSMNQEERFIQMYAEKIYLR
GTRHGTMLVFRDVTHETEVDRLKTELVSTVSHELRTPLTSIIGFTELLRFRKLSAERSEKYLGMIHQETLRLEDLISNLL
DVQRMESGQQTYHNEPERLSAILEQAIAVHQGSSQHHHITFDCTEDVYVYGDRTRLNQLFMNLLHNAVKYSPRGGEINVR
VACERPDWIDISIEDHGIGIPQTALPKLFDKFYRVDNSASRKIGGTGLGLAICKEIAEGHGGTIHATSNIGKGSMFTVSL
PKLDMTNQISS

Sequences:

>Translated_651_residues
MKSWIDQRIGRQFLFVFYLFIGLILLTSLAVYVYTENQIEQTTSSLENISERRTNATELFETWQSMQYEMRGYVLLGDDA
MLERVQDKQVLIDEQTFWFEQNAVTEKEKTYASDARTLFVAYQERVMPSLERYVAGKRDGSVTEPFLKMPTLGKVNPQKD
PPADRKFKINSKSAADMSASIVDMESVFTEYRNSLNAEEDALRAQLATHTKWAQALWLLSLLGVLFILFIVARPYVRRLT
GQLQELIENSKRLAGERQPITPAAAQSKNEVGQLTTSFRQMATSLTTQRYRIEEEREKTARLLHSIRDAVIYVEHATSEK
VANQALFVLFNQPITKRNEVDLYRLDASLEELGLQVDQKDAFFAFMERSFDGQCKEESVTFSMNQEERFIQMYAEKIYLR
GTRHGTMLVFRDVTHETEVDRLKTELVSTVSHELRTPLTSIIGFTELLRFRKLSAERSEKYLGMIHQETLRLEDLISNLL
DVQRMESGQQTYHNEPERLSAILEQAIAVHQGSSQHHHITFDCTEDVYVYGDRTRLNQLFMNLLHNAVKYSPRGGEINVR
VACERPDWIDISIEDHGIGIPQTALPKLFDKFYRVDNSASRKIGGTGLGLAICKEIAEGHGGTIHATSNIGKGSMFTVSL
PKLDMTNQISS
>Mature_651_residues
MKSWIDQRIGRQFLFVFYLFIGLILLTSLAVYVYTENQIEQTTSSLENISERRTNATELFETWQSMQYEMRGYVLLGDDA
MLERVQDKQVLIDEQTFWFEQNAVTEKEKTYASDARTLFVAYQERVMPSLERYVAGKRDGSVTEPFLKMPTLGKVNPQKD
PPADRKFKINSKSAADMSASIVDMESVFTEYRNSLNAEEDALRAQLATHTKWAQALWLLSLLGVLFILFIVARPYVRRLT
GQLQELIENSKRLAGERQPITPAAAQSKNEVGQLTTSFRQMATSLTTQRYRIEEEREKTARLLHSIRDAVIYVEHATSEK
VANQALFVLFNQPITKRNEVDLYRLDASLEELGLQVDQKDAFFAFMERSFDGQCKEESVTFSMNQEERFIQMYAEKIYLR
GTRHGTMLVFRDVTHETEVDRLKTELVSTVSHELRTPLTSIIGFTELLRFRKLSAERSEKYLGMIHQETLRLEDLISNLL
DVQRMESGQQTYHNEPERLSAILEQAIAVHQGSSQHHHITFDCTEDVYVYGDRTRLNQLFMNLLHNAVKYSPRGGEINVR
VACERPDWIDISIEDHGIGIPQTALPKLFDKFYRVDNSASRKIGGTGLGLAICKEIAEGHGGTIHATSNIGKGSMFTVSL
PKLDMTNQISS

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=252, Percent_Identity=36.1111111111111, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI1786600, Length=241, Percent_Identity=34.0248962655602, Blast_Score=139, Evalue=5e-34,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=33.6244541484716, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI1788393, Length=225, Percent_Identity=33.3333333333333, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=35.8407079646018, Blast_Score=119, Evalue=8e-28,
Organism=Escherichia coli, GI1788549, Length=437, Percent_Identity=27.4599542334096, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=31.8777292576419, Blast_Score=108, Evalue=9e-25,
Organism=Escherichia coli, GI1786783, Length=218, Percent_Identity=33.0275229357798, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1788713, Length=257, Percent_Identity=28.4046692607004, Blast_Score=105, Evalue=9e-24,
Organism=Escherichia coli, GI87081816, Length=226, Percent_Identity=31.858407079646, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=30.4545454545455, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790346, Length=231, Percent_Identity=31.1688311688312, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1787894, Length=236, Percent_Identity=30.9322033898305, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1788279, Length=220, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=236, Percent_Identity=26.271186440678, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1790551, Length=202, Percent_Identity=26.7326732673267, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1789403, Length=200, Percent_Identity=28, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=220, Percent_Identity=29.5454545454545, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082128, Length=217, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1787374, Length=221, Percent_Identity=27.6018099547511, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=99, Percent_Identity=42.4242424242424, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 74590; Mature: 74590

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSWIDQRIGRQFLFVFYLFIGLILLTSLAVYVYTENQIEQTTSSLENISERRTNATELF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHCCCHHHHH
ETWQSMQYEMRGYVLLGDDAMLERVQDKQVLIDEQTFWFEQNAVTEKEKTYASDARTLFV
HHHHHHHHHHCCEEEECCHHHHHHHCCCCEEECCHHHEEECCCCCHHHHHHHHHHHHHHH
AYQERVMPSLERYVAGKRDGSVTEPFLKMPTLGKVNPQKDPPADRKFKINSKSAADMSAS
HHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHH
IVDMESVFTEYRNSLNAEEDALRAQLATHTKWAQALWLLSLLGVLFILFIVARPYVRRLT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
GQLQELIENSKRLAGERQPITPAAAQSKNEVGQLTTSFRQMATSLTTQRYRIEEEREKTA
HHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLHSIRDAVIYVEHATSEKVANQALFVLFNQPITKRNEVDLYRLDASLEELGLQVDQKD
HHHHHHHHHEEEEECCCHHHHHHHHEEEEECCCCCCCCCCEEEEECCCHHHHCCCCCCCH
AFFAFMERSFDGQCKEESVTFSMNQEERFIQMYAEKIYLRGTRHGTMLVFRDVTHETEVD
HHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHEECCCCEEEEEECCCCHHHHH
RLKTELVSTVSHELRTPLTSIIGFTELLRFRKLSAERSEKYLGMIHQETLRLEDLISNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVQRMESGQQTYHNEPERLSAILEQAIAVHQGSSQHHHITFDCTEDVYVYGDRTRLNQLF
HHHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCHHHHHHHH
MNLLHNAVKYSPRGGEINVRVACERPDWIDISIEDHGIGIPQTALPKLFDKFYRVDNSAS
HHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCC
RKIGGTGLGLAICKEIAEGHGGTIHATSNIGKGSMFTVSLPKLDMTNQISS
CCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCHHCCCC
>Mature Secondary Structure
MKSWIDQRIGRQFLFVFYLFIGLILLTSLAVYVYTENQIEQTTSSLENISERRTNATELF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHHHCCCHHHHH
ETWQSMQYEMRGYVLLGDDAMLERVQDKQVLIDEQTFWFEQNAVTEKEKTYASDARTLFV
HHHHHHHHHHCCEEEECCHHHHHHHCCCCEEECCHHHEEECCCCCHHHHHHHHHHHHHHH
AYQERVMPSLERYVAGKRDGSVTEPFLKMPTLGKVNPQKDPPADRKFKINSKSAADMSAS
HHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCCCCCCHHHH
IVDMESVFTEYRNSLNAEEDALRAQLATHTKWAQALWLLSLLGVLFILFIVARPYVRRLT
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
GQLQELIENSKRLAGERQPITPAAAQSKNEVGQLTTSFRQMATSLTTQRYRIEEEREKTA
HHHHHHHHHHHHHCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLLHSIRDAVIYVEHATSEKVANQALFVLFNQPITKRNEVDLYRLDASLEELGLQVDQKD
HHHHHHHHHEEEEECCCHHHHHHHHEEEEECCCCCCCCCCEEEEECCCHHHHCCCCCCCH
AFFAFMERSFDGQCKEESVTFSMNQEERFIQMYAEKIYLRGTRHGTMLVFRDVTHETEVD
HHHHHHHHCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHEECCCCEEEEEECCCCHHHHH
RLKTELVSTVSHELRTPLTSIIGFTELLRFRKLSAERSEKYLGMIHQETLRLEDLISNLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVQRMESGQQTYHNEPERLSAILEQAIAVHQGSSQHHHITFDCTEDVYVYGDRTRLNQLF
HHHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCHHHHHHHH
MNLLHNAVKYSPRGGEINVRVACERPDWIDISIEDHGIGIPQTALPKLFDKFYRVDNSAS
HHHHHHHHHCCCCCCEEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCC
RKIGGTGLGLAICKEIAEGHGGTIHATSNIGKGSMFTVSLPKLDMTNQISS
CCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]