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The map label for this gene is putA [H]

Identifier: 229597115

GI number: 229597115

Start: 1788776

End: 1792381

Strand: Direct

Name: putA [H]

Synonym: NMCC_1744

Alternate gene names: 229597115

Gene position: 1788776-1792381 (Clockwise)

Preceding gene: 161870671

Following gene: 161870678

Centisome position: 83.07

GC content: 59.18

Gene sequence:

>3606_bases
ATGTTTCATTTTGCATTTCCGGCACAAACTGCCCTGCGCCAAGCGATAACCGATGCCTACCGCCGTAATGAAATCGAAGC
CGTACAGGATATGTTGCAACGTGCACAGATGAGCGACGAAGAGCGCAACGCCGCCTCCGAGCTTGCCCGCCGTTTGGTTA
CCCAAGTCCGCGCCGGCCGCACCAAAGCCGGCGGCGTGGATGCGCTGATGCACGAGTTTTCACTCTCCAGCGAAGAAGGC
ATCGCGCTGATGTGTCTGGCAGAAGCCCTGCTGCGTATCCCCGACAACGCCACGCGCGACCGCCTGATTGCCGACAAGAT
TTCAGACGGCAACTGGAAAAGCCATTTGAACAACAGCCCTTCCCTCTTCGTCAACGCCGCCGCCTGGGGCCTGCTGATTA
CCGGCAAACTGACCGCCACAAACGACAGACAAATGAGTTCCGCACTCAGCCGCCTGATCAGCAAAGGCGGCGCACCGCTC
ATCCGCCAAGGCGTAAATTACGCCATGCGCCTGTTGGGCAAACAGTTCGTAACCGGACAGACCATTGAAGAAGCCCTGCA
AAACGGCAAAGAACGCGAAAAAATGGGCTACCGCTTCTCCTTCGATATGTTGGGCGAAGCCGCCTACACCCAAGCCGATG
CCGACCGCTACTACCGCGACTATGTCGAAGCCATCCACGCCATCGGCAAAGATGCGGCAGGACAAGGCGTTTACGAAGGC
AACGGCATTTCCGTCAAACTTTCCGCCATCCATCCGCGCTACTCGCGCGCCCAACACGGCCGTGTGATGGGCGAACTGTT
GCCGCGCCTGAAAGAGCTGTTCCTTTTGGGTAAAAAATACGATATCGGTATCAACATCGATGCCGAAGAAGCCAACCGTC
TGGAGCTGTCTTTGGATTTGATGGAGGCTTTGGTTTCAGACCCTGACTTGGCTGGCTACAAAGGTATCGGTTTCGTTGTC
CAAGCCTACCAAAAACGTTGTCCGTTCGTTATCGACTACCTGATTGACCTAGCCCGCCGCAACAACCAAAAACTGATGAT
CCGCCTCGTCAAAGGCGCGTATTGGGACAGCGAAATCAAATGGGCGCAAGTGGACGGCTTGAACGGCTATCCGACCTACA
CCCGCAAAGTCCACACCGACATCTCCTACCTCGCCTGCGCGCGCAAACTGCTTTCCGCGCAAGACGCGGTATTCCCGCAA
TTTGCCACGCACAACGCCTACACCTTAGGCGCAATCTACCAAATGGGCAAAGGCAAAGACTTTGAACACCAATGCCTGCA
CGGCATGGGCGAAACCCTGTACGACCAAGTCGTCGGCCCGCAAAACTTAGGCCGCCGCGTGCGCGTGTACGCCCCGGTCG
GCACACACGAAACCCTGCTCGCCTACTTGGTGCGCCGCCTGTTGGAAAACGGCGCGAACTCGTCTTTCGTCAACCAAATC
GTCGATGAAAACATCAGCATCGACACGCTCATCCGCAGCCCGTTCGACACCATCGCCGAACAAGGCATCCACCTGCACAA
CGCCCTGCCGCTGCCGCGCGATTTGTACGGCAAATGCCGTCTGAACTCGCAAGGCGTGGACTTGAGCAACGAAAACGTAT
TGCAGCAGCTTCAAGAACAGATGAACAAAGCCGCCGCGCAAGACTTCCACGCCGCATCCATCGTCAACGGCAAAGCCCGC
GATGTCGGCGAAGCGCAACCGATTAAAAACCCTGCCGACCACGACGACATCGTCGGCACAGTCAGCTTTGCCGATGCCGC
GCTTGCCCAAGAAGCGGTTGGCGCAGCCGTTGCCGCGTTCCCCGAATGGAGTGCGACACCAGCCGCCGAACGCGCCGCCT
GCCTGCGCCGTTTCGCCGACCTGCTCGAACAGCACACCCCCGCGCTGATGATGCTTGCCGTGCGCGAAGCGGGCAAAACG
CTGAACAACGCCATTGCCGAAGTGCGCGAAGCCGTCGATTTCTGCCGCTACTATGCAAACGAAGCCGAACACACCCTGCC
TCAAGACGCAAAAGCCGTCGGCGCGATTGTCGCCATCAGCCCGTGGAACTTCCCGCTCGCCATCTTTACCGGCGAAGTCG
TTTCCGCATTAGCGGCAGGCAACACCGTTATCGCCAAACCTGCCGAACAAACCGGCCTGATTGCCGGTTACGCCGTTTCC
CTGATGCACGAAGCCGGCATCCTGACTTCCGCCCTGCAACTCGTCCTCGGCGCAGGCGACGTGGGTGCGGCATTGACCAA
CGATGCCCGCATCGGCGGCGTAATTTTCACCGGCTCAACCGAAGTGGCGCGCCTGATCAACAAAGCCCTTGCCAAACGCG
GCGACAATCCCGTCCTGATTGCCGAAACCGGCGGACAAAACGCCATGATTGTCGATTCCACCGCACTTGCCGAACAAGTC
TGCGCCGACGTATTGAACTCCGCCTTCGACAGCGCGGGACAACGCTGCTCCGCCCTGCGTATCTTGTGCGTCCAAGAAGA
CGTTGCCGACCGTATGCTCGACATGATCAAAGGCGCGATGGACGAACTCGTCGTCGGCAAACCGATTCAGCTCACTACCG
ATGTCGGCCCCGTCATCGATGCCGAAGCACAGCAAAACCTGTTGAACCACATCAACAAAATGAAAGGCGTTGCCAAGTCT
TACCACGAAGTCAAAACCGCTGCCGATGTCGATTCCGAAAAATCCACGTTCGTCCGCCCCATCCTGTTTGAATTGAACAA
CCTCAACGAACTGCAACGCGAAGTCTTCGGTCCCGTCCTGCACGTCGTCCGCTACCGCGCCGACGAACTCGACAACGTCA
TCGACCAAATCAACAGCAAAGGCTACGCCCTGACCCACGGCGTACACAGCCGCATCGAAGGCACGGTACGCCACATCCGC
AGCCGCATCGAAGCCGGCAACGTTTACGTCAACCGCAACATCGTCGGCGCAGTCGTCGGCGTACAGCCCTTCGGCGGACA
CGGTCTGTCCGGCACAGGCCCCAAAGCAGGCGGTTCGTTCTACCTGCAAAAACTGACCCGCGCCGGCGAATGGGTTGCCC
CGACCCTGAGCCAAATCGGACAGGCGGACGAAGCCGCACTCAAACGCCTCGAAGCACTGGTTCACAAACTGCCGTTCAAC
GCCGAAGAGAAAAAAGCCGCAGCGGCCGCTTTGGGACACGCCCGCATCCGCACCCTGCGCCGTGCCGAAACCGTCCTTAC
CGGACCGACCGGCGAGCGCAACAGCATCTCATGGCACGCGCCAAAACGAGTTTGGATACACGGCGGCAGCACGGTTCAAG
CCTTTGCCGCACTGACCGAACTTGCCGCCTCCGGCGTACAGGCAGTGGTCGAACCCGACAGCCCGCTGGCTTCCTACACC
GCCGACTTGGAAGGTCTGCTGCTGGTCAACGGCAAACCCGAAACCGTCGGCATCAGCCACGTTGCCGCCCTGTCGCCTTT
GGACAGCGCGCGCAAACAGGAACTTGCCGCCCACGACGGCGCACTCATCCGCGTCCTCCCTTCGGAAAACGGACTCGACA
TCCTGCAAGTTTTTGAAGAAATCTCTTGCAGCGTCAACACCACAGCCGCCGGCGGCAACGCCAGCCTGATGGCGGTTGCC
GACTGA

Upstream 100 bases:

>100_bases
GAAGCCTTGTATTTCATCTGCGGATTTATTACGATATTACCGTATTCAGACCGCACCGATGCCGTCTGAACCCCCCGAAA
AACTTTGGAGAATCCAAAAA

Downstream 100 bases:

>100_bases
TTTTGCCAAAACCGCCCGAGCGCGGCCCGTGAACCAATGCCGTCTGAAAACCTTTCAGACGGCATTTTTATAGTGGATTA
ACAAAAATCAGGACAAGACG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1201; Mature: 1201

Protein sequence:

>1201_residues
MFHFAFPAQTALRQAITDAYRRNEIEAVQDMLQRAQMSDEERNAASELARRLVTQVRAGRTKAGGVDALMHEFSLSSEEG
IALMCLAEALLRIPDNATRDRLIADKISDGNWKSHLNNSPSLFVNAAAWGLLITGKLTATNDRQMSSALSRLISKGGAPL
IRQGVNYAMRLLGKQFVTGQTIEEALQNGKEREKMGYRFSFDMLGEAAYTQADADRYYRDYVEAIHAIGKDAAGQGVYEG
NGISVKLSAIHPRYSRAQHGRVMGELLPRLKELFLLGKKYDIGINIDAEEANRLELSLDLMEALVSDPDLAGYKGIGFVV
QAYQKRCPFVIDYLIDLARRNNQKLMIRLVKGAYWDSEIKWAQVDGLNGYPTYTRKVHTDISYLACARKLLSAQDAVFPQ
FATHNAYTLGAIYQMGKGKDFEHQCLHGMGETLYDQVVGPQNLGRRVRVYAPVGTHETLLAYLVRRLLENGANSSFVNQI
VDENISIDTLIRSPFDTIAEQGIHLHNALPLPRDLYGKCRLNSQGVDLSNENVLQQLQEQMNKAAAQDFHAASIVNGKAR
DVGEAQPIKNPADHDDIVGTVSFADAALAQEAVGAAVAAFPEWSATPAAERAACLRRFADLLEQHTPALMMLAVREAGKT
LNNAIAEVREAVDFCRYYANEAEHTLPQDAKAVGAIVAISPWNFPLAIFTGEVVSALAAGNTVIAKPAEQTGLIAGYAVS
LMHEAGILTSALQLVLGAGDVGAALTNDARIGGVIFTGSTEVARLINKALAKRGDNPVLIAETGGQNAMIVDSTALAEQV
CADVLNSAFDSAGQRCSALRILCVQEDVADRMLDMIKGAMDELVVGKPIQLTTDVGPVIDAEAQQNLLNHINKMKGVAKS
YHEVKTAADVDSEKSTFVRPILFELNNLNELQREVFGPVLHVVRYRADELDNVIDQINSKGYALTHGVHSRIEGTVRHIR
SRIEAGNVYVNRNIVGAVVGVQPFGGHGLSGTGPKAGGSFYLQKLTRAGEWVAPTLSQIGQADEAALKRLEALVHKLPFN
AEEKKAAAAALGHARIRTLRRAETVLTGPTGERNSISWHAPKRVWIHGGSTVQAFAALTELAASGVQAVVEPDSPLASYT
ADLEGLLLVNGKPETVGISHVAALSPLDSARKQELAAHDGALIRVLPSENGLDILQVFEEISCSVNTTAAGGNASLMAVA
D

Sequences:

>Translated_1201_residues
MFHFAFPAQTALRQAITDAYRRNEIEAVQDMLQRAQMSDEERNAASELARRLVTQVRAGRTKAGGVDALMHEFSLSSEEG
IALMCLAEALLRIPDNATRDRLIADKISDGNWKSHLNNSPSLFVNAAAWGLLITGKLTATNDRQMSSALSRLISKGGAPL
IRQGVNYAMRLLGKQFVTGQTIEEALQNGKEREKMGYRFSFDMLGEAAYTQADADRYYRDYVEAIHAIGKDAAGQGVYEG
NGISVKLSAIHPRYSRAQHGRVMGELLPRLKELFLLGKKYDIGINIDAEEANRLELSLDLMEALVSDPDLAGYKGIGFVV
QAYQKRCPFVIDYLIDLARRNNQKLMIRLVKGAYWDSEIKWAQVDGLNGYPTYTRKVHTDISYLACARKLLSAQDAVFPQ
FATHNAYTLGAIYQMGKGKDFEHQCLHGMGETLYDQVVGPQNLGRRVRVYAPVGTHETLLAYLVRRLLENGANSSFVNQI
VDENISIDTLIRSPFDTIAEQGIHLHNALPLPRDLYGKCRLNSQGVDLSNENVLQQLQEQMNKAAAQDFHAASIVNGKAR
DVGEAQPIKNPADHDDIVGTVSFADAALAQEAVGAAVAAFPEWSATPAAERAACLRRFADLLEQHTPALMMLAVREAGKT
LNNAIAEVREAVDFCRYYANEAEHTLPQDAKAVGAIVAISPWNFPLAIFTGEVVSALAAGNTVIAKPAEQTGLIAGYAVS
LMHEAGILTSALQLVLGAGDVGAALTNDARIGGVIFTGSTEVARLINKALAKRGDNPVLIAETGGQNAMIVDSTALAEQV
CADVLNSAFDSAGQRCSALRILCVQEDVADRMLDMIKGAMDELVVGKPIQLTTDVGPVIDAEAQQNLLNHINKMKGVAKS
YHEVKTAADVDSEKSTFVRPILFELNNLNELQREVFGPVLHVVRYRADELDNVIDQINSKGYALTHGVHSRIEGTVRHIR
SRIEAGNVYVNRNIVGAVVGVQPFGGHGLSGTGPKAGGSFYLQKLTRAGEWVAPTLSQIGQADEAALKRLEALVHKLPFN
AEEKKAAAAALGHARIRTLRRAETVLTGPTGERNSISWHAPKRVWIHGGSTVQAFAALTELAASGVQAVVEPDSPLASYT
ADLEGLLLVNGKPETVGISHVAALSPLDSARKQELAAHDGALIRVLPSENGLDILQVFEEISCSVNTTAAGGNASLMAVA
D
>Mature_1201_residues
MFHFAFPAQTALRQAITDAYRRNEIEAVQDMLQRAQMSDEERNAASELARRLVTQVRAGRTKAGGVDALMHEFSLSSEEG
IALMCLAEALLRIPDNATRDRLIADKISDGNWKSHLNNSPSLFVNAAAWGLLITGKLTATNDRQMSSALSRLISKGGAPL
IRQGVNYAMRLLGKQFVTGQTIEEALQNGKEREKMGYRFSFDMLGEAAYTQADADRYYRDYVEAIHAIGKDAAGQGVYEG
NGISVKLSAIHPRYSRAQHGRVMGELLPRLKELFLLGKKYDIGINIDAEEANRLELSLDLMEALVSDPDLAGYKGIGFVV
QAYQKRCPFVIDYLIDLARRNNQKLMIRLVKGAYWDSEIKWAQVDGLNGYPTYTRKVHTDISYLACARKLLSAQDAVFPQ
FATHNAYTLGAIYQMGKGKDFEHQCLHGMGETLYDQVVGPQNLGRRVRVYAPVGTHETLLAYLVRRLLENGANSSFVNQI
VDENISIDTLIRSPFDTIAEQGIHLHNALPLPRDLYGKCRLNSQGVDLSNENVLQQLQEQMNKAAAQDFHAASIVNGKAR
DVGEAQPIKNPADHDDIVGTVSFADAALAQEAVGAAVAAFPEWSATPAAERAACLRRFADLLEQHTPALMMLAVREAGKT
LNNAIAEVREAVDFCRYYANEAEHTLPQDAKAVGAIVAISPWNFPLAIFTGEVVSALAAGNTVIAKPAEQTGLIAGYAVS
LMHEAGILTSALQLVLGAGDVGAALTNDARIGGVIFTGSTEVARLINKALAKRGDNPVLIAETGGQNAMIVDSTALAEQV
CADVLNSAFDSAGQRCSALRILCVQEDVADRMLDMIKGAMDELVVGKPIQLTTDVGPVIDAEAQQNLLNHINKMKGVAKS
YHEVKTAADVDSEKSTFVRPILFELNNLNELQREVFGPVLHVVRYRADELDNVIDQINSKGYALTHGVHSRIEGTVRHIR
SRIEAGNVYVNRNIVGAVVGVQPFGGHGLSGTGPKAGGSFYLQKLTRAGEWVAPTLSQIGQADEAALKRLEALVHKLPFN
AEEKKAAAAALGHARIRTLRRAETVLTGPTGERNSISWHAPKRVWIHGGSTVQAFAALTELAASGVQAVVEPDSPLASYT
ADLEGLLLVNGKPETVGISHVAALSPLDSARKQELAAHDGALIRVLPSENGLDILQVFEEISCSVNTTAAGGNASLMAVA
D

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=455, Percent_Identity=31.4285714285714, Blast_Score=186, Evalue=8e-47,
Organism=Homo sapiens, GI153266822, Length=447, Percent_Identity=30.8724832214765, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI25777724, Length=454, Percent_Identity=30.6167400881057, Blast_Score=179, Evalue=1e-44,
Organism=Homo sapiens, GI25777730, Length=451, Percent_Identity=31.2638580931264, Blast_Score=179, Evalue=2e-44,
Organism=Homo sapiens, GI25777736, Length=471, Percent_Identity=32.484076433121, Blast_Score=175, Evalue=3e-43,
Organism=Homo sapiens, GI25777734, Length=471, Percent_Identity=32.484076433121, Blast_Score=175, Evalue=3e-43,
Organism=Homo sapiens, GI238859541, Length=471, Percent_Identity=32.484076433121, Blast_Score=174, Evalue=6e-43,
Organism=Homo sapiens, GI25777732, Length=460, Percent_Identity=29.5652173913043, Blast_Score=172, Evalue=2e-42,
Organism=Homo sapiens, GI25777728, Length=406, Percent_Identity=30.2955665024631, Blast_Score=167, Evalue=7e-41,
Organism=Homo sapiens, GI238814322, Length=509, Percent_Identity=27.7013752455796, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI21614513, Length=456, Percent_Identity=28.9473684210526, Blast_Score=150, Evalue=5e-36,
Organism=Homo sapiens, GI12007648, Length=434, Percent_Identity=28.110599078341, Blast_Score=147, Evalue=8e-35,
Organism=Homo sapiens, GI310128103, Length=477, Percent_Identity=26.8343815513627, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI188035924, Length=477, Percent_Identity=26.8343815513627, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI25777726, Length=453, Percent_Identity=27.5938189845475, Blast_Score=144, Evalue=6e-34,
Organism=Homo sapiens, GI310128093, Length=472, Percent_Identity=26.9067796610169, Blast_Score=142, Evalue=1e-33,
Organism=Homo sapiens, GI4507229, Length=478, Percent_Identity=29.2887029288703, Blast_Score=140, Evalue=1e-32,
Organism=Homo sapiens, GI25777721, Length=491, Percent_Identity=28.7169042769857, Blast_Score=131, Evalue=5e-30,
Organism=Homo sapiens, GI25952152, Length=423, Percent_Identity=27.4231678486998, Blast_Score=124, Evalue=7e-28,
Organism=Homo sapiens, GI115387104, Length=438, Percent_Identity=24.4292237442922, Blast_Score=124, Evalue=8e-28,
Organism=Homo sapiens, GI310128091, Length=390, Percent_Identity=26.6666666666667, Blast_Score=119, Evalue=3e-26,
Organism=Homo sapiens, GI11095441, Length=465, Percent_Identity=25.1612903225806, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI206597441, Length=454, Percent_Identity=24.8898678414097, Blast_Score=109, Evalue=2e-23,
Organism=Homo sapiens, GI206597439, Length=454, Percent_Identity=24.8898678414097, Blast_Score=109, Evalue=2e-23,
Organism=Homo sapiens, GI22907049, Length=454, Percent_Identity=24.8898678414097, Blast_Score=109, Evalue=2e-23,
Organism=Homo sapiens, GI310128087, Length=287, Percent_Identity=29.616724738676, Blast_Score=108, Evalue=4e-23,
Organism=Homo sapiens, GI4502043, Length=324, Percent_Identity=25.6172839506173, Blast_Score=103, Evalue=9e-22,
Organism=Homo sapiens, GI238814371, Length=324, Percent_Identity=25.6172839506173, Blast_Score=103, Evalue=9e-22,
Organism=Homo sapiens, GI71773324, Length=324, Percent_Identity=25.6172839506173, Blast_Score=103, Evalue=1e-21,
Organism=Homo sapiens, GI4557303, Length=329, Percent_Identity=24.6200607902736, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI73466520, Length=329, Percent_Identity=24.6200607902736, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI310128089, Length=333, Percent_Identity=26.7267267267267, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI73695881, Length=325, Percent_Identity=24.6153846153846, Blast_Score=89, Evalue=4e-17,
Organism=Homo sapiens, GI73695879, Length=325, Percent_Identity=24.6153846153846, Blast_Score=89, Evalue=4e-17,
Organism=Homo sapiens, GI310128101, Length=238, Percent_Identity=28.1512605042017, Blast_Score=89, Evalue=4e-17,
Organism=Homo sapiens, GI310128099, Length=238, Percent_Identity=28.1512605042017, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI310128095, Length=316, Percent_Identity=25.6329113924051, Blast_Score=81, Evalue=5e-15,
Organism=Homo sapiens, GI310128097, Length=263, Percent_Identity=26.2357414448669, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI223972651, Length=384, Percent_Identity=25, Blast_Score=70, Evalue=2e-11,
Organism=Escherichia coli, GI1787250, Length=1243, Percent_Identity=52.4537409493162, Blast_Score=1167, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=476, Percent_Identity=32.1428571428571, Blast_Score=180, Evalue=4e-46,
Organism=Escherichia coli, GI1788042, Length=423, Percent_Identity=30.0236406619385, Blast_Score=157, Evalue=3e-39,
Organism=Escherichia coli, GI87081896, Length=451, Percent_Identity=30.1552106430155, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1787558, Length=422, Percent_Identity=30.0947867298578, Blast_Score=149, Evalue=2e-36,
Organism=Escherichia coli, GI1787715, Length=461, Percent_Identity=29.2841648590022, Blast_Score=146, Evalue=7e-36,
Organism=Escherichia coli, GI1787684, Length=453, Percent_Identity=27.1523178807947, Blast_Score=139, Evalue=2e-33,
Organism=Escherichia coli, GI87082295, Length=432, Percent_Identity=28.9351851851852, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1786504, Length=458, Percent_Identity=25.764192139738, Blast_Score=117, Evalue=6e-27,
Organism=Escherichia coli, GI87081926, Length=428, Percent_Identity=25.4672897196262, Blast_Score=114, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17534447, Length=511, Percent_Identity=29.7455968688845, Blast_Score=167, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI25144435, Length=448, Percent_Identity=30.8035714285714, Blast_Score=166, Evalue=7e-41,
Organism=Caenorhabditis elegans, GI17562198, Length=431, Percent_Identity=30.8584686774942, Blast_Score=161, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI32564736, Length=407, Percent_Identity=30.7125307125307, Blast_Score=158, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI115534176, Length=483, Percent_Identity=28.5714285714286, Blast_Score=156, Evalue=7e-38,
Organism=Caenorhabditis elegans, GI133930964, Length=477, Percent_Identity=28.3018867924528, Blast_Score=151, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI115532534, Length=382, Percent_Identity=30.6282722513089, Blast_Score=142, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI25143874, Length=422, Percent_Identity=27.4881516587678, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI25143876, Length=422, Percent_Identity=27.4881516587678, Blast_Score=134, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI17551164, Length=437, Percent_Identity=28.3752860411899, Blast_Score=128, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI32564151, Length=459, Percent_Identity=28.1045751633987, Blast_Score=128, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17534119, Length=473, Percent_Identity=24.7357293868922, Blast_Score=124, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71986308, Length=478, Percent_Identity=26.1506276150628, Blast_Score=120, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI71995606, Length=440, Percent_Identity=25.4545454545455, Blast_Score=115, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71990744, Length=351, Percent_Identity=28.7749287749288, Blast_Score=104, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71995613, Length=397, Percent_Identity=24.6851385390428, Blast_Score=103, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25146391, Length=321, Percent_Identity=24.9221183800623, Blast_Score=97, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=321, Percent_Identity=24.9221183800623, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=321, Percent_Identity=24.9221183800623, Blast_Score=96, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=436, Percent_Identity=24.0825688073394, Blast_Score=93, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6325196, Length=463, Percent_Identity=30.0215982721382, Blast_Score=170, Evalue=1e-42,
Organism=Saccharomyces cerevisiae, GI6324950, Length=424, Percent_Identity=29.2452830188679, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6320917, Length=447, Percent_Identity=30.4250559284116, Blast_Score=160, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6323821, Length=453, Percent_Identity=30.0220750551876, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6323822, Length=461, Percent_Identity=30.1518438177874, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6321826, Length=523, Percent_Identity=28.1070745697897, Blast_Score=148, Evalue=7e-36,
Organism=Saccharomyces cerevisiae, GI6319478, Length=472, Percent_Identity=25.635593220339, Blast_Score=134, Evalue=6e-32,
Organism=Saccharomyces cerevisiae, GI6323757, Length=325, Percent_Identity=26.4615384615385, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI20129399, Length=450, Percent_Identity=30.2222222222222, Blast_Score=175, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24668425, Length=525, Percent_Identity=28, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24668417, Length=525, Percent_Identity=28, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24668413, Length=525, Percent_Identity=28, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281362580, Length=453, Percent_Identity=29.5805739514349, Blast_Score=161, Evalue=3e-39,
Organism=Drosophila melanogaster, GI62472918, Length=453, Percent_Identity=29.5805739514349, Blast_Score=161, Evalue=3e-39,
Organism=Drosophila melanogaster, GI62472926, Length=453, Percent_Identity=29.5805739514349, Blast_Score=161, Evalue=3e-39,
Organism=Drosophila melanogaster, GI62472936, Length=453, Percent_Identity=29.5805739514349, Blast_Score=161, Evalue=3e-39,
Organism=Drosophila melanogaster, GI21356737, Length=453, Percent_Identity=29.5805739514349, Blast_Score=161, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24650465, Length=445, Percent_Identity=28.9887640449438, Blast_Score=154, Evalue=3e-37,
Organism=Drosophila melanogaster, GI24666674, Length=441, Percent_Identity=26.984126984127, Blast_Score=152, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24585660, Length=473, Percent_Identity=26.0042283298097, Blast_Score=149, Evalue=2e-35,
Organism=Drosophila melanogaster, GI28574525, Length=470, Percent_Identity=25.1063829787234, Blast_Score=137, Evalue=3e-32,
Organism=Drosophila melanogaster, GI28571802, Length=487, Percent_Identity=23.6139630390144, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28571800, Length=487, Percent_Identity=23.6139630390144, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28571806, Length=487, Percent_Identity=23.6139630390144, Blast_Score=117, Evalue=4e-26,
Organism=Drosophila melanogaster, GI28571798, Length=487, Percent_Identity=23.6139630390144, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28571796, Length=487, Percent_Identity=23.6139630390144, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28571794, Length=487, Percent_Identity=23.6139630390144, Blast_Score=117, Evalue=5e-26,
Organism=Drosophila melanogaster, GI45552499, Length=355, Percent_Identity=27.0422535211268, Blast_Score=113, Evalue=8e-25,
Organism=Drosophila melanogaster, GI281360303, Length=355, Percent_Identity=27.0422535211268, Blast_Score=113, Evalue=9e-25,
Organism=Drosophila melanogaster, GI281360299, Length=355, Percent_Identity=25.6338028169014, Blast_Score=107, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281360297, Length=355, Percent_Identity=25.6338028169014, Blast_Score=107, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281360295, Length=355, Percent_Identity=25.6338028169014, Blast_Score=107, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24586250, Length=355, Percent_Identity=25.6338028169014, Blast_Score=107, Evalue=5e-23,
Organism=Drosophila melanogaster, GI281360301, Length=355, Percent_Identity=25.6338028169014, Blast_Score=107, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24638878, Length=467, Percent_Identity=26.1241970021413, Blast_Score=99, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24638876, Length=467, Percent_Identity=26.1241970021413, Blast_Score=99, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 129937; Mature: 129937

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHFAFPAQTALRQAITDAYRRNEIEAVQDMLQRAQMSDEERNAASELARRLVTQVRAGR
CCEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
TKAGGVDALMHEFSLSSEEGIALMCLAEALLRIPDNATRDRLIADKISDGNWKSHLNNSP
CCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHCCCCC
SLFVNAAAWGLLITGKLTATNDRQMSSALSRLISKGGAPLIRQGVNYAMRLLGKQFVTGQ
CEEEEEEEEEEEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCH
TIEEALQNGKEREKMGYRFSFDMLGEAAYTQADADRYYRDYVEAIHAIGKDAAGQGVYEG
HHHHHHHCCHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEC
NGISVKLSAIHPRYSRAQHGRVMGELLPRLKELFLLGKKYDIGINIDAEEANRLELSLDL
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHH
MEALVSDPDLAGYKGIGFVVQAYQKRCPFVIDYLIDLARRNNQKLMIRLVKGAYWDSEIK
HHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHEEHHHHHCCCCCCCCC
WAQVDGLNGYPTYTRKVHTDISYLACARKLLSAQDAVFPQFATHNAYTLGAIYQMGKGKD
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEHHHHHHCCCCCC
FEHQCLHGMGETLYDQVVGPQNLGRRVRVYAPVGTHETLLAYLVRRLLENGANSSFVNQI
HHHHHHHHHHHHHHHHHCCCHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHH
VDENISIDTLIRSPFDTIAEQGIHLHNALPLPRDLYGKCRLNSQGVDLSNENVLQQLQEQ
HHCCCCHHHHHCCHHHHHHHCCCEECCCCCCCHHHCCCEEECCCCCCCCCHHHHHHHHHH
MNKAAAQDFHAASIVNGKARDVGEAQPIKNPADHDDIVGTVSFADAALAQEAVGAAVAAF
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHCC
PEWSATPAAERAACLRRFADLLEQHTPALMMLAVREAGKTLNNAIAEVREAVDFCRYYAN
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EAEHTLPQDAKAVGAIVAISPWNFPLAIFTGEVVSALAAGNTVIAKPAEQTGLIAGYAVS
CHHHCCCCCHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHCHHHHHHHH
LMHEAGILTSALQLVLGAGDVGAALTNDARIGGVIFTGSTEVARLINKALAKRGDNPVLI
HHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEE
AETGGQNAMIVDSTALAEQVCADVLNSAFDSAGQRCSALRILCVQEDVADRMLDMIKGAM
EECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEHHHHHHHHHHHHHHHHHH
DELVVGKPIQLTTDVGPVIDAEAQQNLLNHINKMKGVAKSYHEVKTAADVDSEKSTFVRP
HHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ILFELNNLNELQREVFGPVLHVVRYRADELDNVIDQINSKGYALTHGVHSRIEGTVRHIR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
SRIEAGNVYVNRNIVGAVVGVQPFGGHGLSGTGPKAGGSFYLQKLTRAGEWVAPTLSQIG
HHHCCCCEEEECCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCC
QADEAALKRLEALVHKLPFNAEEKKAAAAALGHARIRTLRRAETVLTGPTGERNSISWHA
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEECC
PKRVWIHGGSTVQAFAALTELAASGVQAVVEPDSPLASYTADLEGLLLVNGKPETVGISH
CCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCCEEEECCCCCEECHHH
VAALSPLDSARKQELAAHDGALIRVLPSENGLDILQVFEEISCSVNTTAAGGNASLMAVA
HHHHCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
D
C
>Mature Secondary Structure
MFHFAFPAQTALRQAITDAYRRNEIEAVQDMLQRAQMSDEERNAASELARRLVTQVRAGR
CCEECCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
TKAGGVDALMHEFSLSSEEGIALMCLAEALLRIPDNATRDRLIADKISDGNWKSHLNNSP
CCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHCCCCC
SLFVNAAAWGLLITGKLTATNDRQMSSALSRLISKGGAPLIRQGVNYAMRLLGKQFVTGQ
CEEEEEEEEEEEEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCH
TIEEALQNGKEREKMGYRFSFDMLGEAAYTQADADRYYRDYVEAIHAIGKDAAGQGVYEG
HHHHHHHCCHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEC
NGISVKLSAIHPRYSRAQHGRVMGELLPRLKELFLLGKKYDIGINIDAEEANRLELSLDL
CCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHH
MEALVSDPDLAGYKGIGFVVQAYQKRCPFVIDYLIDLARRNNQKLMIRLVKGAYWDSEIK
HHHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHEEHHHHHCCCCCCCCC
WAQVDGLNGYPTYTRKVHTDISYLACARKLLSAQDAVFPQFATHNAYTLGAIYQMGKGKD
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEEHHHHHHCCCCCC
FEHQCLHGMGETLYDQVVGPQNLGRRVRVYAPVGTHETLLAYLVRRLLENGANSSFVNQI
HHHHHHHHHHHHHHHHHCCCHHCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHH
VDENISIDTLIRSPFDTIAEQGIHLHNALPLPRDLYGKCRLNSQGVDLSNENVLQQLQEQ
HHCCCCHHHHHCCHHHHHHHCCCEECCCCCCCHHHCCCEEECCCCCCCCCHHHHHHHHHH
MNKAAAQDFHAASIVNGKARDVGEAQPIKNPADHDDIVGTVSFADAALAQEAVGAAVAAF
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHEEEHHHHHHHHHHHHHHHHHHCC
PEWSATPAAERAACLRRFADLLEQHTPALMMLAVREAGKTLNNAIAEVREAVDFCRYYAN
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EAEHTLPQDAKAVGAIVAISPWNFPLAIFTGEVVSALAAGNTVIAKPAEQTGLIAGYAVS
CHHHCCCCCHHHHEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEECCCHHHCHHHHHHHH
LMHEAGILTSALQLVLGAGDVGAALTNDARIGGVIFTGSTEVARLINKALAKRGDNPVLI
HHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEE
AETGGQNAMIVDSTALAEQVCADVLNSAFDSAGQRCSALRILCVQEDVADRMLDMIKGAM
EECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEHHHHHHHHHHHHHHHHHH
DELVVGKPIQLTTDVGPVIDAEAQQNLLNHINKMKGVAKSYHEVKTAADVDSEKSTFVRP
HHHHCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
ILFELNNLNELQREVFGPVLHVVRYRADELDNVIDQINSKGYALTHGVHSRIEGTVRHIR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHH
SRIEAGNVYVNRNIVGAVVGVQPFGGHGLSGTGPKAGGSFYLQKLTRAGEWVAPTLSQIG
HHHCCCCEEEECCEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCC
QADEAALKRLEALVHKLPFNAEEKKAAAAALGHARIRTLRRAETVLTGPTGERNSISWHA
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCEEECC
PKRVWIHGGSTVQAFAALTELAASGVQAVVEPDSPLASYTADLEGLLLVNGKPETVGISH
CCEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHCCCCCEEEECCCCCEECHHH
VAALSPLDSARKQELAAHDGALIRVLPSENGLDILQVFEEISCSVNTTAAGGNASLMAVA
HHHHCCHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEE
D
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]