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The map label for this gene is nadA [H]

Identifier: 161870678

GI number: 161870678

Start: 1798710

End: 1799822

Strand: Direct

Name: nadA [H]

Synonym: NMCC_1750

Alternate gene names: 161870678

Gene position: 1798710-1799822 (Clockwise)

Preceding gene: 229597115

Following gene: 161870679

Centisome position: 83.53

GC content: 59.03

Gene sequence:

>1113_bases
ATGCAAACCGCCGCCCGCCGCTCGTTCGACTACGATATGCCACTCATCCAAACGCCGACTTCCGCCTGCCAAATCCGTCA
GGCGTGGGCGAAGGTTGCCGACACGCCCGACCGCGAGACGGCAGATCGTCTGAAAGACGAAATCAAGGCTTTGCTGAAGG
AGAAAAACGCGGTCTTGGTGGCGCATTATTATGTTGATCCGCTGATTCAGGATTTGGCTTTGGAAACGGGCGGATGCGTG
GGCGATTCTCTGGAAATGGCACGCTTCGGCGCGGAACACGAAGCCGGTACGCTGGTGGTGGCGGGCGTGCGTTTCATGGG
AGAGAGCGCGAAAATCCTCTGCCCTGAAAAAACGGTGCTGATGCCTGATTTGGAAGCGGAATGTTCTTTGGATTTGGGTT
GCCCGGAAGAGGCGTTTTCGGCGTTTTGCGACCAACACCCCGACCGCACGGTGGTGGTGTACGCCAACACTTCCGCCGCC
GTGAAAGCGCGTGCCGATTGGGTGGTAACGTCTTCGGTGGCGTTGGAAATCGTGTCGTATCTGAAATCGCGCGGCGAGAA
GCTGATTTGGGGGCCCGACCGCCACCTCGGCGACTACATCCGCCGCGAAACGGGCGCGGATATGCTGTTGTGGCAGGGTT
CGTGCATCGTCCACAACGAATTTAAAGGGCAGGAGCTGGCGGCGTTGAAGGCGGAACACCCCGATGCGGTGGTGCTGGTT
CATCCCGAATCGCCACAAAGCGTCATCGAACTGGGCGACGTGGTCGGCTCGACCAGCAAACTGCTGAAAGCTGCCGTATC
ACGCCCCGAAAAAAAATTCATCGTGGCGACCGATTTGGGCATCCTGCACGAAATGCAAAAGCAGGCGCCCGACAAAGAAT
TTATCGCCGCGCCGACGGCGGGCAACGGCGGAAGTTGCAAAAGCTGCGCGTTCTGCCCGTGGATGGCGATGAATTCGCTG
GGCGGCATCAAATACGCCCTGACAAGCGGACGTAACGAAATCCTGTTGGACAGGAAGCTGGGCGAAGCCGCCAAACTGCC
TTTGCAGCGTATGCTCGACTTCGCGGCAGGACTCAAACGCGGGGATGTGTTCAACGGCATGGGGCCCGCCTGA

Upstream 100 bases:

>100_bases
CCTTGCTTATTATACTCAATTTGAGCATAATATAAAAATATTTCAAAATATAAACGGCAAATCTTTATGCCGTCTGAAAA
ACCAGCCATAAGGAAGTCTC

Downstream 100 bases:

>100_bases
TTTGCCGTCCATATTGCCGTTTCAGACGACCTCTCCAACAAGGACAACACCATGCAAACCGATTGCGACGTATTGATTGC
CGGAAACGGGCTGGCGGCAC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETADRLKDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCV
GDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAA
VKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYIRRETGADMLLWQGSCIVHNEFKGQELAALKAEHPDAVVLV
HPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKEFIAAPTAGNGGSCKSCAFCPWMAMNSL
GGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKRGDVFNGMGPA

Sequences:

>Translated_370_residues
MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETADRLKDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCV
GDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAA
VKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYIRRETGADMLLWQGSCIVHNEFKGQELAALKAEHPDAVVLV
HPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKEFIAAPTAGNGGSCKSCAFCPWMAMNSL
GGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKRGDVFNGMGPA
>Mature_370_residues
MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETADRLKDEIKALLKEKNAVLVAHYYVDPLIQDLALETGGCV
GDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVLMPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAA
VKARADWVVTSSVALEIVSYLKSRGEKLIWGPDRHLGDYIRRETGADMLLWQGSCIVHNEFKGQELAALKAEHPDAVVLV
HPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKEFIAAPTAGNGGSCKSCAFCPWMAMNSL
GGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKRGDVFNGMGPA

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=317, Percent_Identity=64.9842271293375, Blast_Score=447, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 40162; Mature: 40162

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETADRLKDEIKALLKEKNAVLV
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEE
AHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVL
EEHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCEEEEEEHHHCCCCCEEECCCCEEE
MPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSVALEIVSY
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHH
LKSRGEKLIWGPDRHLGDYIRRETGADMLLWQGSCIVHNEFKGQELAALKAEHPDAVVLV
HHHCCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCHHHHEECCCCCEEEEE
HPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKEFIAAPTA
CCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCCCCEEECCCC
GNGGSCKSCAFCPWMAMNSLGGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKR
CCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHCCCHHHHHHHHHCCCC
GDVFNGMGPA
CCCCCCCCCC
>Mature Secondary Structure
MQTAARRSFDYDMPLIQTPTSACQIRQAWAKVADTPDRETADRLKDEIKALLKEKNAVLV
CCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEE
AHYYVDPLIQDLALETGGCVGDSLEMARFGAEHEAGTLVVAGVRFMGESAKILCPEKTVL
EEHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCEEEEEEHHHCCCCCEEECCCCEEE
MPDLEAECSLDLGCPEEAFSAFCDQHPDRTVVVYANTSAAVKARADWVVTSSVALEIVSY
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHH
LKSRGEKLIWGPDRHLGDYIRRETGADMLLWQGSCIVHNEFKGQELAALKAEHPDAVVLV
HHHCCCEEEECCCHHHHHHHHHHCCCCEEEECCCEEEECCCCCCHHHHEECCCCCEEEEE
HPESPQSVIELGDVVGSTSKLLKAAVSRPEKKFIVATDLGILHEMQKQAPDKEFIAAPTA
CCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHCCCCCEEECCCC
GNGGSCKSCAFCPWMAMNSLGGIKYALTSGRNEILLDRKLGEAAKLPLQRMLDFAAGLKR
CCCCCCCCCCCCHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHCCCHHHHHHHHHCCCC
GDVFNGMGPA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA