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The map label for this gene is iroN [H]

Identifier: 229220624

GI number: 229220624

Start: 2762521

End: 2764695

Strand: Reverse

Name: iroN [H]

Synonym: t2672

Alternate gene names: 229220624

Gene position: 2764695-2762521 (Counterclockwise)

Preceding gene: 29143043

Following gene: 29143036

Centisome position: 57.69

GC content: 50.85

Gene sequence:

>2175_bases
ATGAGAGTTAAGAAGTTCATCTGGTTAATAACCGTGGTTTCTACAGGGATTAATAGTCCATTATCAGCAGCAGAATCTAC
AGACGACAACGGCGAAACGATAGTGGTTGAATCCACTGCCGAGCAAGTATTAAAGCAACAGCCGGGCGTTTCGATTATTA
CTCGTGACGATATTCAGAAGAATCCTCCCGTTAACGATCTTGCCGATATTATTCGTAAGATGCCTGGGGTTAATCTTACC
AGCAATAGCGCCTCGGGGACGCGCGGAAATAACCGACAAATTGATATTCGTGGTATGGGGCCGGAAAATACCTTAGTGCT
GATTGACGGCGTGCCGGTGACGTCGCGAAATTCGGTTCGCTATAGCTGGCGCGGAGAACGCGACACCCGTGGCGATACGA
ACTGGGTGCCGCCGGAGATGGTAGAACGTATTGAAATGATCCGTGGGCCCGCCGCCGCGCGCTATGGCTCCGGTGCCGCA
GGCGGGGTGGTGAACATCATCACCAAACGCCCCACTAACGACTGGCATGGCTCGCTGTCGCTTTATACCAACTACCCGGA
AAGCAGCAAAGAAGGTGACACCCGGCGGGGTAACTTTAGCCTTAGCGGCCCGTTGGCTGGTGATACGTTGACGATGCGCC
TGTACGGTAATCTCAACAGAACCGATGCCGACAGCTGGGATATTAACTCCTCCGCCGGTACCAAAAATGCCGCCGGACGG
GAGGGGGTCACCAATAAAGATATTAATAGCGTCTTCTCATGGAAAATGACCCCGCAGCAAATCCTTGATTTTGAAGCGGG
ATACAGTCGGCAGGGGAATATCTATGCCGGCGATACGCAAAACAGTAATTCAAACGCGGTTACCAAAAGTCTGGCGCAGT
CCGGGCGGGAGACCAATCGCCTGTACCGGCAGAATTACGGTCTAACTCATAACGGCATCTGGGGCTGGGGGCAAAGCCGC
CTGGGGTTCTACTATGAAAAAACCGATAATACCCGCATGAATGAGGGACTCTCCGGCGGCGGCGAGGGGCGTATTACCAA
CGACCAGACGTTCACCACTAACCGCCTGACCTCGTATCGCACCAGCGGCGAGGTGAATGTCCCGGTGATATGGCTATTTG
AGCAAACGCTCACCGTCGGCGCGGAGTGGAACCGCGATGAGCTGAACGATCCTTCCTCTACCAGTCTGACGGTTAAGGAT
AGCAATATCGCCGGGATTCCCGGTTCGGCGGCTAACCGTAGCAGTAAAAATAAATCGGAAATCAGTGCGCTGTACGTTGA
AGATAATATCGAACCCATGGCCGGTACCAATATTATTCCGGGTCTGCGTTTTGACTATTTGAGCGAATCCGGGAGTAATT
TTAGTCCCAGTCTTAACCTTTCCCAGGAGTTAGGTGAATTCGTCAAGGTGAAAGCCGGTATTGCCCGGGCCTTTAAGGCA
CCGAACTTGTATCAAACCAGTGAGGGGTATTTACTCTATTCGAAAGGCAACGGTTGTCCAAAAGATATTACGTCGGGCGG
CTGTTACCTGGTTGGTAATAAGAACCTCGATCCTGAAATTAGTATCAATAAAGAGATTGGGCTGGAATTTACCGTAGACG
ATTATCACGCAAGCGTAACGTATTTCCGTAACGATTATCAGAATAAGATTGTCGCAGGTGATCAGATTATTGGCAGAAGC
GCATCTGGCGCTTATGTATTGCAGTGGCAGAACGGCGGTAAAGCGCTGATTGAAGGTATTGAAGCCAGCATGGCTGTTCC
GCTGATGCCGGACCGTCTGAACTGGAATACCAATGCGACTTATATGATCACTTCTGAGCAAAAAGATACCGGTAATCCCT
TATCGATAATCCCGAAATATACGGTGAATACCTTCCTCGACTGGACTATCACCAACGCGCTCTCCGCTAACGTCAACTGG
ACGTTATACGGCAAGCAAAAACCGCGAACACATGCGGAGTCGCGTAGTGAAGAGACCAAAGGATTGTCCGGGAAAGCGCT
GGGGGCTTACTCACTGGTCGGCGCTAACGTTAACTACGATATCAATAAGAACCTGCGTCTTAATGTCGGTATCAGCAATA
TCTTCGATAAACAGATCTATCGCTCCGCCGAAGGGGCAAATACCTATAACGAACCGGGTCGGGCTTATTATGCCGGTGTG
ACGGCCTCGTTTTGA

Upstream 100 bases:

>100_bases
ATCATTAGCATATGATAATAATTACTATATAGCCGTAACCTGGCAAGGATGTGAGCTTGAGGGCAACAGCGCTACTTTAG
ACATTATTTAGGGAATGGGT

Downstream 100 bases:

>100_bases
TGGGTTATGCCCGCCGCTGGCGGGCATATTCTGGCGACGGGTTAATGGCAGCGTGGTTCTTAGCTTGCCGGTTCGCGACT
GATACCCAGCAATGCACTAC

Product: outer membrane receptor FepA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 724; Mature: 724

Protein sequence:

>724_residues
MRVKKFIWLITVVSTGINSPLSAAESTDDNGETIVVESTAEQVLKQQPGVSIITRDDIQKNPPVNDLADIIRKMPGVNLT
SNSASGTRGNNRQIDIRGMGPENTLVLIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEMVERIEMIRGPAAARYGSGAA
GGVVNIITKRPTNDWHGSLSLYTNYPESSKEGDTRRGNFSLSGPLAGDTLTMRLYGNLNRTDADSWDINSSAGTKNAAGR
EGVTNKDINSVFSWKMTPQQILDFEAGYSRQGNIYAGDTQNSNSNAVTKSLAQSGRETNRLYRQNYGLTHNGIWGWGQSR
LGFYYEKTDNTRMNEGLSGGGEGRITNDQTFTTNRLTSYRTSGEVNVPVIWLFEQTLTVGAEWNRDELNDPSSTSLTVKD
SNIAGIPGSAANRSSKNKSEISALYVEDNIEPMAGTNIIPGLRFDYLSESGSNFSPSLNLSQELGEFVKVKAGIARAFKA
PNLYQTSEGYLLYSKGNGCPKDITSGGCYLVGNKNLDPEISINKEIGLEFTVDDYHASVTYFRNDYQNKIVAGDQIIGRS
ASGAYVLQWQNGGKALIEGIEASMAVPLMPDRLNWNTNATYMITSEQKDTGNPLSIIPKYTVNTFLDWTITNALSANVNW
TLYGKQKPRTHAESRSEETKGLSGKALGAYSLVGANVNYDINKNLRLNVGISNIFDKQIYRSAEGANTYNEPGRAYYAGV
TASF

Sequences:

>Translated_724_residues
MRVKKFIWLITVVSTGINSPLSAAESTDDNGETIVVESTAEQVLKQQPGVSIITRDDIQKNPPVNDLADIIRKMPGVNLT
SNSASGTRGNNRQIDIRGMGPENTLVLIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEMVERIEMIRGPAAARYGSGAA
GGVVNIITKRPTNDWHGSLSLYTNYPESSKEGDTRRGNFSLSGPLAGDTLTMRLYGNLNRTDADSWDINSSAGTKNAAGR
EGVTNKDINSVFSWKMTPQQILDFEAGYSRQGNIYAGDTQNSNSNAVTKSLAQSGRETNRLYRQNYGLTHNGIWGWGQSR
LGFYYEKTDNTRMNEGLSGGGEGRITNDQTFTTNRLTSYRTSGEVNVPVIWLFEQTLTVGAEWNRDELNDPSSTSLTVKD
SNIAGIPGSAANRSSKNKSEISALYVEDNIEPMAGTNIIPGLRFDYLSESGSNFSPSLNLSQELGEFVKVKAGIARAFKA
PNLYQTSEGYLLYSKGNGCPKDITSGGCYLVGNKNLDPEISINKEIGLEFTVDDYHASVTYFRNDYQNKIVAGDQIIGRS
ASGAYVLQWQNGGKALIEGIEASMAVPLMPDRLNWNTNATYMITSEQKDTGNPLSIIPKYTVNTFLDWTITNALSANVNW
TLYGKQKPRTHAESRSEETKGLSGKALGAYSLVGANVNYDINKNLRLNVGISNIFDKQIYRSAEGANTYNEPGRAYYAGV
TASF
>Mature_724_residues
MRVKKFIWLITVVSTGINSPLSAAESTDDNGETIVVESTAEQVLKQQPGVSIITRDDIQKNPPVNDLADIIRKMPGVNLT
SNSASGTRGNNRQIDIRGMGPENTLVLIDGVPVTSRNSVRYSWRGERDTRGDTNWVPPEMVERIEMIRGPAAARYGSGAA
GGVVNIITKRPTNDWHGSLSLYTNYPESSKEGDTRRGNFSLSGPLAGDTLTMRLYGNLNRTDADSWDINSSAGTKNAAGR
EGVTNKDINSVFSWKMTPQQILDFEAGYSRQGNIYAGDTQNSNSNAVTKSLAQSGRETNRLYRQNYGLTHNGIWGWGQSR
LGFYYEKTDNTRMNEGLSGGGEGRITNDQTFTTNRLTSYRTSGEVNVPVIWLFEQTLTVGAEWNRDELNDPSSTSLTVKD
SNIAGIPGSAANRSSKNKSEISALYVEDNIEPMAGTNIIPGLRFDYLSESGSNFSPSLNLSQELGEFVKVKAGIARAFKA
PNLYQTSEGYLLYSKGNGCPKDITSGGCYLVGNKNLDPEISINKEIGLEFTVDDYHASVTYFRNDYQNKIVAGDQIIGRS
ASGAYVLQWQNGGKALIEGIEASMAVPLMPDRLNWNTNATYMITSEQKDTGNPLSIIPKYTVNTFLDWTITNALSANVNW
TLYGKQKPRTHAESRSEETKGLSGKALGAYSLVGANVNYDINKNLRLNVGISNIFDKQIYRSAEGANTYNEPGRAYYAGV
TASF

Specific function: Specific receptor for the siderophore ferric enterobactin [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786798, Length=753, Percent_Identity=52.058432934927, Blast_Score=710, Evalue=0.0,
Organism=Escherichia coli, GI1788478, Length=731, Percent_Identity=33.515731874145, Blast_Score=309, Evalue=4e-85,
Organism=Escherichia coli, GI1790405, Length=720, Percent_Identity=25, Blast_Score=100, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79275; Mature: 79275

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00449 ATPASE_A ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVKKFIWLITVVSTGINSPLSAAESTDDNGETIVVESTAEQVLKQQPGVSIITRDDIQK
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHCCCCEEEECCCCCC
NPPVNDLADIIRKMPGVNLTSNSASGTRGNNRQIDIRGMGPENTLVLIDGVPVTSRNSVR
CCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCEE
YSWRGERDTRGDTNWVPPEMVERIEMIRGPAAARYGSGAAGGVVNIITKRPTNDWHGSLS
EEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEECCCCCCCCCEEE
LYTNYPESSKEGDTRRGNFSLSGPLAGDTLTMRLYGNLNRTDADSWDINSSAGTKNAAGR
EEECCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
EGVTNKDINSVFSWKMTPQQILDFEAGYSRQGNIYAGDTQNSNSNAVTKSLAQSGRETNR
CCCCCCCCHHHEEECCCHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCHHHHH
LYRQNYGLTHNGIWGWGQSRLGFYYEKTDNTRMNEGLSGGGEGRITNDQTFTTNRLTSYR
HHHHCCCCCCCCEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEE
TSGEVNVPVIWLFEQTLTVGAEWNRDELNDPSSTSLTVKDSNIAGIPGSAANRSSKNKSE
CCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
ISALYVEDNIEPMAGTNIIPGLRFDYLSESGSNFSPSLNLSQELGEFVKVKAGIARAFKA
EEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
PNLYQTSEGYLLYSKGNGCPKDITSGGCYLVGNKNLDPEISINKEIGLEFTVDDYHASVT
CCCEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCEEEECCCEEEEE
YFRNDYQNKIVAGDQIIGRSASGAYVLQWQNGGKALIEGIEASMAVPLMPDRLNWNTNAT
EEECCCCCCEEECCCEECCCCCCEEEEEECCCCHHHHHHHHHCEECCCCCCCCCCCCCEE
YMITSEQKDTGNPLSIIPKYTVNTFLDWTITNALSANVNWTLYGKQKPRTHAESRSEETK
EEEECCCCCCCCCEEEEECCEEEEEEEEEEECEEECCEEEEEEECCCCCCHHHHCHHHHC
GLSGKALGAYSLVGANVNYDINKNLRLNVGISNIFDKQIYRSAEGANTYNEPGRAYYAGV
CCCCCCCCEEEEEECCEEEECCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
TASF
EECC
>Mature Secondary Structure
MRVKKFIWLITVVSTGINSPLSAAESTDDNGETIVVESTAEQVLKQQPGVSIITRDDIQK
CCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHCCCCEEEECCCCCC
NPPVNDLADIIRKMPGVNLTSNSASGTRGNNRQIDIRGMGPENTLVLIDGVPVTSRNSVR
CCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCEEEEEECCCCCCEEEEECCCCCCCCCEE
YSWRGERDTRGDTNWVPPEMVERIEMIRGPAAARYGSGAAGGVVNIITKRPTNDWHGSLS
EEECCCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEECCCCCCCCCEEE
LYTNYPESSKEGDTRRGNFSLSGPLAGDTLTMRLYGNLNRTDADSWDINSSAGTKNAAGR
EEECCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCCC
EGVTNKDINSVFSWKMTPQQILDFEAGYSRQGNIYAGDTQNSNSNAVTKSLAQSGRETNR
CCCCCCCCHHHEEECCCHHHHHCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHCCHHHHH
LYRQNYGLTHNGIWGWGQSRLGFYYEKTDNTRMNEGLSGGGEGRITNDQTFTTNRLTSYR
HHHHCCCCCCCCEECCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEE
TSGEVNVPVIWLFEQTLTVGAEWNRDELNDPSSTSLTVKDSNIAGIPGSAANRSSKNKSE
CCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCC
ISALYVEDNIEPMAGTNIIPGLRFDYLSESGSNFSPSLNLSQELGEFVKVKAGIARAFKA
EEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCC
PNLYQTSEGYLLYSKGNGCPKDITSGGCYLVGNKNLDPEISINKEIGLEFTVDDYHASVT
CCCEECCCCEEEEECCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCEEEECCCEEEEE
YFRNDYQNKIVAGDQIIGRSASGAYVLQWQNGGKALIEGIEASMAVPLMPDRLNWNTNAT
EEECCCCCCEEECCCEECCCCCCEEEEEECCCCHHHHHHHHHCEECCCCCCCCCCCCCEE
YMITSEQKDTGNPLSIIPKYTVNTFLDWTITNALSANVNWTLYGKQKPRTHAESRSEETK
EEEECCCCCCCCCEEEEECCEEEEEEEEEEECEEECCEEEEEEECCCCCCHHHHCHHHHC
GLSGKALGAYSLVGANVNYDINKNLRLNVGISNIFDKQIYRSAEGANTYNEPGRAYYAGV
CCCCCCCCEEEEEECCEEEECCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
TASF
EECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419284; 10984043 [H]